Regulog FapR - Staphylococcaceae

Properties
Regulator type:	Transcription factor
Regulator family:	FapR
Regulation mode:	repressor
Biological process:	Fatty acid biosynthesis
Effector:	Malonyl-CoA; Malonyl-ACP
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 30 sites [see more]

Member of regulog collections

By taxonomy - Staphylococcaceae
By TF family - FapR
By effector - Malonyl-CoA
By effector - Malonyl-ACP
By pathway - Fatty acid biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Staphylococcus aureus subsp. aureus N315	8	4
Staphylococcus capitis SK14	10	5
Staphylococcus epidermidis ATCC 12228	8	4
Staphylococcus carnosus subsp. carnosus TM300	7	3
Staphylococcus haemolyticus JCSC1435	10	5
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	9	4
Macrococcus caseolyticus JCSC5402	10	5

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes								Function

CRON 1.
scoA	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -46 score = 6.06791 sequence = ATTAGTACTAGGTATTAAA Gene: SSP2200: succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A	Macrococcus caseolyticus JCSC5402	succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A
scoB	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP2199: succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B	Macrococcus caseolyticus JCSC5402	succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B

CRON 2.
perR	* Staphylococcus aureus subsp. aureus N315 Site: position = -49 score = 4.75387 sequence = ATTTATAGTAAGTAATAAT Gene: SA1678: peroxide-responsive repressor PerR	* Staphylococcus capitis SK14 Site: position = -48 score = 5.35521 sequence = ATTAATATTAAGTAATAAT Gene: STACA0001_1914: peroxide-responsive repressor PerR	* Staphylococcus epidermidis ATCC 12228 Site: position = -48 score = 5.35521 sequence = ATTAATATTAAGTAATAAT Gene: SE1545: peroxide-responsive repressor PerR	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -48 score = 4.75387 sequence = ATTTATAGTAAGTAATAAT Gene: Sca_1434: peroxide-responsive repressor PerR	* Staphylococcus haemolyticus JCSC1435 Site: position = -47 score = 5.51485 sequence = ATTAATATCAAGTAATAAT Gene: SH1102: peroxide-responsive repressor PerR	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -48 score = 5.35521 sequence = ATTAATATTAAGTAATAAT Gene: SSP0932: peroxide-responsive repressor PerR	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1591: peroxide-responsive repressor PerR	peroxide-responsive repressor PerR

CRON 3.
fapR	* Staphylococcus aureus subsp. aureus N315 Site: position = -36 score = 5.96857 sequence = TTTAAGACTAGGTACTAAA Gene: SA1071: transcriptional regulator of fatty acid biosynthesis	* Staphylococcus capitis SK14 Site: position = -34 score = 5.96857 sequence = TTTAAGACTTGGTACTAAA Gene: STACA0001_2225: transcriptional regulator of fatty acid biosynthesis	* Staphylococcus epidermidis ATCC 12228 Site: position = 17 score = 5.96857 sequence = TTTAAGACTTGGTACTAAA Gene: SE0903: transcriptional regulator of fatty acid biosynthesis	Staphylococcus carnosus subsp. carnosus TM300	* Staphylococcus haemolyticus JCSC1435 Site: position = -42 score = 5.88983 sequence = TTTAAGACTTGGTACTAAT Gene: SH1686: transcriptional regulator of fatty acid biosynthesis	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -39 score = 5.96857 sequence = TTTAAGACTTGGTACTAAA Gene: SSP1541: transcriptional regulator of fatty acid biosynthesis	* Macrococcus caseolyticus JCSC5402 Site: position = -34 score = 5.45574 sequence = ATTAAGACCAACTACTAAT Gene: MCCL_0813: transcriptional regulator of fatty acid biosynthesis	transcriptional regulator of fatty acid biosynthesis
plsX	Staphylococcus aureus subsp. aureus N315 Gene: SA1072: fatty acid/phospholipid synthesis protein PlsX	Staphylococcus capitis SK14 Gene: STACA0001_2226: fatty acid/phospholipid synthesis protein PlsX	Staphylococcus epidermidis ATCC 12228 Gene: SE0904: fatty acid/phospholipid synthesis protein PlsX	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0852: fatty acid/phospholipid synthesis protein PlsX	Staphylococcus haemolyticus JCSC1435 Gene: SH1685: fatty acid/phospholipid synthesis protein PlsX	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1540: fatty acid phospholipid synthesis protein PlsX	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0814: fatty acid/phospholipid synthesis protein PlsX	fatty acid/phospholipid synthesis protein PlsX
fabD	Staphylococcus aureus subsp. aureus N315 Gene: SA1073: malonyl CoA-acyl carrier protein transacylase	Staphylococcus capitis SK14 Gene: STACA0001_2227: malonyl CoA-acyl carrier protein transacylase	Staphylococcus epidermidis ATCC 12228 Gene: SE0905: malonyl CoA-acyl carrier protein transacylase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0853: malonyl CoA-acyl carrier protein transacylase	Staphylococcus haemolyticus JCSC1435 Gene: SH1684: malonyl CoA-acyl carrier protein transacylase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1539: malonyl CoA-acyl carrier protein transacylase	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0815: malonyl CoA-acyl carrier protein transacylase	malonyl CoA-acyl carrier protein transacylase
fabG	Staphylococcus aureus subsp. aureus N315 Gene: SA1074: 3-oxoacyl-(acyl-carrier protein) reductase	Staphylococcus capitis SK14 Gene: STACA0001_2228: 3-oxoacyl-(acyl-carrier protein) reductase	Staphylococcus epidermidis ATCC 12228 Gene: SE0906: 3-oxoacyl-(acyl-carrier protein) reductase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0854: 3-oxoacyl-(acyl-carrier protein) reductase	Staphylococcus haemolyticus JCSC1435 Gene: SH1683: 3-oxoacyl-(acyl-carrier protein) reductase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1538: 3-oxoacyl-(acyl-carrier protein) reductase	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0816: 3-oxoacyl-(acyl-carrier protein) reductase	3-oxoacyl-(acyl-carrier protein) reductase
fapR	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -36 score = 5.55185 sequence = CTTAAGACTTGGTACTAAA Gene: Sca_0851: transcriptional regulator of fatty acid biosynthesis	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	transcriptional regulator of fatty acid biosynthesis

CRON 4.
fabI	* Staphylococcus aureus subsp. aureus N315 Site: position = -111 score = 4.70365 sequence = TTTATTAAAAAGTCATAAT Gene: SA0869: enoyl-(acyl carrier protein) reductase	* Staphylococcus capitis SK14 Site: position = -112 score = 5.79128 sequence = TTTATTATCAGGTACTAAA Gene: STACA0001_0124: enoyl-(acyl carrier protein) reductase	* Staphylococcus epidermidis ATCC 12228 Site: position = -109 score = 5.79128 sequence = TTTATTATCAGGTACTAAA Gene: SE0712: enoyl-(acyl carrier protein) reductase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0612: enoyl-(acyl carrier protein) reductase	* Staphylococcus haemolyticus JCSC1435 Site: position = -131 score = 5.28643 sequence = TATATGACCAGGTAATAAT Gene: SH1947: enoyl-(acyl carrier protein) reductase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1774: enoyl-(acyl carrier protein) reductase	* Macrococcus caseolyticus JCSC5402 Site: position = -45 score = 5.26621 sequence = TTTAGTAGTAGGTACTAGA Gene: MCCL_0625: enoyl-[acyl-carrier-protein] reductase	enoyl-(acyl carrier protein) reductase

CRON 5.
fabH	* Staphylococcus aureus subsp. aureus N315 Site: position = -44 score = 6.26824 sequence = ATTAATACCTGGTATTAAA Gene: SA0842: 3-oxoacyl-[acyl-carrier-protein] synthase III	* Staphylococcus capitis SK14 Site: position = -44 score = 6.26824 sequence = ATTAATACCTGGTATTAAA Gene: STACA0001_0149: 3-oxoacyl-[acyl-carrier-protein] synthase III	* Staphylococcus epidermidis ATCC 12228 Site: position = -43 score = 6.26824 sequence = ATTAATACCTGGTATTAAA Gene: SE0677: 3-oxoacyl-[acyl-carrier-protein] synthase III	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -44 score = 6.26824 sequence = ATTAATACCTGGTATTAAA Gene: Sca_0584: putative 3-oxoacyl-[acyl-carrier-protein] synthase III	* Staphylococcus haemolyticus JCSC1435 Site: position = -44 score = 6.26824 sequence = ATTAATACCTGGTATTAAA Gene: SH1973: 3-oxoacyl-[acyl-carrier-protein] synthase III	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -44 score = 6.26824 sequence = ATTAATACCTGGTATTAAA Gene: SSP1798: 3-oxoacyl-[acyl-carrier-protein] synthase III	* Macrococcus caseolyticus JCSC5402 Site: position = -42 score = 5.83151 sequence = ATTAGTACCAGATACTAAA Gene: MCCL_0603: 3-oxoacyl-[acyl-carrier-protein] synthase III	3-oxoacyl-[acyl-carrier-protein] synthase III
fabF	Staphylococcus aureus subsp. aureus N315 Gene: SA0843: 3-oxoacyl-[acyl-carrier-protein] synthase II	Staphylococcus capitis SK14 Gene: STACA0001_0148: 3-oxoacyl-[acyl-carrier-protein] synthase II	Staphylococcus epidermidis ATCC 12228 Gene: SE0678: 3-oxoacyl-[acyl-carrier-protein] synthase II	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0585: 3-oxoacyl-[acyl-carrier-protein] synthase II	Staphylococcus haemolyticus JCSC1435 Gene: SH1972: 3-oxoacyl-[acyl-carrier-protein] synthase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1797: 3-oxoacyl-[acyl-carrier-protein] synthase II	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0604: 3-oxoacyl-[acyl-carrier-protein] synthase II	3-oxoacyl-[acyl-carrier-protein] synthase II

CRON 6.
desA	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	* Macrococcus caseolyticus JCSC5402 Site: position = -100 score = 5.82951 sequence = ATTAGTACTAGGTAATAAT Gene: MCCL_0154: Omega-6 fatty acid desaturase	Omega-6 fatty acid desaturase

CRON 7.
accB	Staphylococcus aureus subsp. aureus N315 Gene: SA1358: acetyl-CoA carboxylase biotin carboxyl carrier subunit	* Staphylococcus capitis SK14 Site: position = -164 score = 4.48303 sequence = ATTAATAATCATTACTAAA Gene: STACA0001_1765: acetyl-CoA carboxylase biotin carboxyl carrier subunit	Staphylococcus epidermidis ATCC 12228 Gene: SE1208: acetyl-CoA carboxylase biotin carboxyl carrier subunit	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1151: acetyl-CoA carboxylase biotin carboxyl carrier subunit	* Staphylococcus haemolyticus JCSC1435 Site: position = -121 score = 4.39831 sequence = AATAATAATAAGCATTAAA Gene: SH1388: acetyl-CoA carboxylase biotin carboxyl carrier subunit	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1227: acetyl-CoA carboxylase biotin carboxyl carrier subunit	* Macrococcus caseolyticus JCSC5402 Site: position = -41 score = 5.53448 sequence = ATTAGTAGCTAGTCTTAAA Gene: MCCL_1173: acetyl-CoA carboxylase biotin carboxyl carrier subunit	acetyl-CoA carboxylase biotin carboxyl carrier subunit
accC	Staphylococcus aureus subsp. aureus N315 Gene: SA1357: biotin carboxylase subunit of acetyl-CoA carboxylase	Staphylococcus capitis SK14 Gene: STACA0001_1764: biotin carboxylase subunit of acetyl-CoA carboxylase	Staphylococcus epidermidis ATCC 12228 Gene: SE1207: biotin carboxylase subunit of acetyl-CoA carboxylase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1150: biotin carboxylase subunit of acetyl-CoA carboxylase	Staphylococcus haemolyticus JCSC1435 Gene: SH1389: biotin carboxylase subunit of acetyl-CoA carboxylase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1228: biotin carboxylase subunit of acetyl-CoA carboxylase	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1172: biotin carboxylase subunit of acetyl-CoA carboxylase	biotin carboxylase subunit of acetyl-CoA carboxylase

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog FapR - Staphylococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --