Regulog AgrA - Staphylococcaceae

Properties
Regulator type:	Transcription factor
Regulator family:	LytTR
Regulation mode:	activator
Biological process:	Virulence; Quorum sensing
Effector:
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 7 sites [see more]

Member of regulog collections

By taxonomy - Staphylococcaceae
By TF family - LytTR
By pathway - Virulence
By pathway - Quorum sensing

Statistics of regulated genes
Genome	Genes	Operons
Staphylococcus aureus subsp. aureus N315	5	2
Staphylococcus capitis SK14	4	1
Staphylococcus epidermidis ATCC 12228	4	1
Staphylococcus carnosus subsp. carnosus TM300	5	1
Staphylococcus haemolyticus JCSC1435	4	1
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	4	1
Macrococcus caseolyticus JCSC5402

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes								Function

CRON 1.
hld	* Staphylococcus aureus subsp. aureus N315 Site: position = -103 score = 8.30067 sequence = ACAGTTAAG-(12)-CTAGTTAAG Gene: SAS065: delta-hemolysin	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228 Gene: SE1634: delta-haemolysin	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	delta-hemolysin

CRON 2.
agrB	* Staphylococcus aureus subsp. aureus N315 Site: position = -91 score = 8.98067 sequence = ACAGTTAAG-(12)-ACAGTTAGG Gene: SA1842: quorum sensig autoregualated system, secretory protein for the AgrD export and processing	Staphylococcus capitis SK14	* Staphylococcus epidermidis ATCC 12228 Site: position = -92 score = 8.69906 sequence = ACACTTAGG-(12)-ACAGTTAGG Gene: SE1635: quorum sensig autoregualated system, secretory protein for the AgrD export and processing	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -88 score = 8.50078 sequence = ACAGTTAGG-(12)-ACAGTTGGG Gene: Sca_1545: quorum sensig autoregualated system, secretory protein for the AgrD export and processing	* Staphylococcus haemolyticus JCSC1435 Site: position = -91 score = 8.96067 sequence = ACAGTTAAG-(12)-ACAGTTAAG Gene: SH0996: quorum sensig autoregualated system, secretory protein for the AgrD export and processing	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -89 score = 8.98079 sequence = ACAGTTAGG-(12)-ACAGTTAAG Gene: SSP0842: quorum sensig autoregualated system, secretory protein for the AgrD export and processing	Macrococcus caseolyticus JCSC5402	quorum sensig autoregualated system, secretory protein for the AgrD export and processing
agrD	Staphylococcus aureus subsp. aureus N315 Gene: SAS066: quorum sensig autoregualated system, signaling peptide	Staphylococcus capitis SK14 Gene: STACA0001_2129: quorum sensig autoregualated system, signaling peptide	Staphylococcus epidermidis ATCC 12228 Gene: SE1636: quorum sensig autoregualated system, signaling peptide	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1546: quorum sensig autoregualated system, signaling peptide	Staphylococcus haemolyticus JCSC1435 Gene: SH0995: quorum sensig autoregualated system, signaling peptide	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0841: quorum sensig autoregualated system, signaling peptide	Macrococcus caseolyticus JCSC5402	quorum sensig autoregualated system, signaling peptide
agrC	Staphylococcus aureus subsp. aureus N315 Gene: SA1843: quorum sensig autoregualated system, two-component system sensor kinase	Staphylococcus capitis SK14 Gene: STACA0001_2128: quorum sensig autoregualated system, two-component system sensor kinase	Staphylococcus epidermidis ATCC 12228 Gene: SE1637: quorum sensig autoregualated system, two-component system sensor kinase	2 Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1548: quorum sensig autoregualated system, two-component system sensor kinase, C-terminal domain Gene: Sca_1547: quorum sensig autoregualated system, two-component system sensor kinase, N-terminal domain	Staphylococcus haemolyticus JCSC1435 Gene: SH0994: quorum sensig autoregualated system, two-component system sensor kinase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0840: quorum sensig autoregualated system, two-component system sensor kinase	Macrococcus caseolyticus JCSC5402	quorum sensig autoregualated system, two-component system sensor kinase
agrA	Staphylococcus aureus subsp. aureus N315 Gene: SA1844: quorum sensig autoregualated system, response regulator	Staphylococcus capitis SK14 Gene: STACA0001_2127: quorum sensig autoregualated system, response regulator	Staphylococcus epidermidis ATCC 12228 Gene: SE1638: quorum sensig autoregualated system, response regulator	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1549: quorum sensig autoregualated system, response regulator	Staphylococcus haemolyticus JCSC1435 Gene: SH0993: quorum sensig autoregualated system, response regulator	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0839: quorum sensig autoregualated system, response regulator	Macrococcus caseolyticus JCSC5402	quorum sensig autoregualated system, response regulator
agrB	Staphylococcus aureus subsp. aureus N315	* Staphylococcus capitis SK14 Site: position = -92 score = 8.69906 sequence = ACACTTAGG-(12)-ACAGTTAGG Gene: STACA0001_2130: quorum sensig autoregualated system, secretory protein for the AgrD export and processing	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	quorum sensig autoregualated system, secretory protein for the AgrD export and processing

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog AgrA - Staphylococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --