Regulog Lysine - Staphylococcaceae

Properties
Regulator type:	RNA regulatory element
Name:	Lysine
RFAM:	RF00168
Regulation mode:
Biological process:	Lysine biosynthesis
Effector:	Lysine
Phylum:	Firmicutes

Member of regulog collections

By taxonomy - Staphylococcaceae
By RNA motif - Lysine
By effector - Lysine
By pathway - Lysine biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Staphylococcus aureus subsp. aureus N315	9	2
Staphylococcus capitis SK14	9	2
Staphylococcus epidermidis ATCC 12228	9	2
Staphylococcus carnosus subsp. carnosus TM300	9	2
Staphylococcus haemolyticus JCSC1435	9	2
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	9	2
Macrococcus caseolyticus JCSC5402	9	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes								Function

CRON 1.
lysC	* Staphylococcus aureus subsp. aureus N315 Site: position = -256 score = 87.03 sequence = TATTTTGATGAGGCG... Gene: SA1225: Aspartokinase (EC 2.7.2.4)	* Staphylococcus capitis SK14 Site: position = -261 score = 92.6 sequence = GATTTTGATGAGGAG... Gene: STACA0001_1639: Aspartokinase (EC 2.7.2.4)	* Staphylococcus epidermidis ATCC 12228 Site: position = -232 score = 98.39 sequence = GATTTTGATGAGGCG... Gene: SE1073: Aspartokinase (EC 2.7.2.4)	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -261 score = 98.14 sequence = TATTTTGATGAGGCG... Gene: Sca_1037: Aspartokinase (EC 2.7.2.4)	* Staphylococcus haemolyticus JCSC1435 Site: position = -259 score = 103.18 sequence = AAGAAATTGATGAGG... Gene: SH1518: Aspartokinase (EC 2.7.2.4)	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -262 score = 99.65 sequence = AAGGTTTTGATGAGG... Gene: SSP1357: Aspartokinase (EC 2.7.2.4)	* Macrococcus caseolyticus JCSC5402 Site: position = -244 score = 88.74 sequence = GAAACAGATGAGGCG... Gene: MCCL_1048: Aspartokinase (EC 2.7.2.4)	Aspartokinase (EC 2.7.2.4)
asd	Staphylococcus aureus subsp. aureus N315 Gene: SA1226: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)	Staphylococcus capitis SK14 Gene: STACA0001_1640: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)	Staphylococcus epidermidis ATCC 12228 Gene: SE1074: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1038: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)	Staphylococcus haemolyticus JCSC1435 Gene: SH1517: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1356: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1049: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)	Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)
dapA	Staphylococcus aureus subsp. aureus N315 Gene: SA1227: Dihydrodipicolinate synthase (EC 4.2.1.52)	Staphylococcus capitis SK14 Gene: STACA0001_1641: Dihydrodipicolinate synthase (EC 4.2.1.52)	Staphylococcus epidermidis ATCC 12228 Gene: SE1075: Dihydrodipicolinate synthase (EC 4.2.1.52)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1039: Dihydrodipicolinate synthase (EC 4.2.1.52)	Staphylococcus haemolyticus JCSC1435 Gene: SH1516: Dihydrodipicolinate synthase (EC 4.2.1.52)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1355: Dihydrodipicolinate synthase (EC 4.2.1.52)	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1050: Dihydrodipicolinate synthase (EC 4.2.1.52)	Dihydrodipicolinate synthase (EC 4.2.1.52)
dapB	Staphylococcus aureus subsp. aureus N315 Gene: SA1228: Dihydrodipicolinate reductase (EC 1.3.1.26)	Staphylococcus capitis SK14 Gene: STACA0001_1642: Dihydrodipicolinate reductase (EC 1.3.1.26)	Staphylococcus epidermidis ATCC 12228 Gene: SE1076: Dihydrodipicolinate reductase (EC 1.3.1.26)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1040: Dihydrodipicolinate reductase (EC 1.3.1.26)	Staphylococcus haemolyticus JCSC1435 Gene: SH1515: Dihydrodipicolinate reductase (EC 1.3.1.26)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1354: Dihydrodipicolinate reductase (EC 1.3.1.26)	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1051: Dihydrodipicolinate reductase (EC 1.3.1.26)	Dihydrodipicolinate reductase (EC 1.3.1.26)
dapD	Staphylococcus aureus subsp. aureus N315 Gene: SA1229: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89)	Staphylococcus capitis SK14 Gene: STACA0001_1643: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89)	Staphylococcus epidermidis ATCC 12228 Gene: SE1077: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1041: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89)	Staphylococcus haemolyticus JCSC1435 Gene: SH1514: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1353: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89)	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1052: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89)	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89)
dapL	Staphylococcus aureus subsp. aureus N315 Gene: SA1230: N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)	Staphylococcus capitis SK14 Gene: STACA0001_1644: N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)	Staphylococcus epidermidis ATCC 12228 Gene: SE1078: N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1042: N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)	Staphylococcus haemolyticus JCSC1435 Gene: SH1513: N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1352: N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1053: N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)	N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)
dapX	Staphylococcus aureus subsp. aureus N315 Gene: SA1231: Diaminopimelate epimerase alternative form predicted for S.aureus (EC 5.1.1.7)	Staphylococcus capitis SK14 Gene: STACA0001_1645: Diaminopimelate epimerase alternative form predicted for S.aureus (EC 5.1.1.7)	Staphylococcus epidermidis ATCC 12228 Gene: SE1079: Diaminopimelate epimerase alternative form predicted for S.aureus (EC 5.1.1.7)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1043: Diaminopimelate epimerase alternative form predicted for S.aureus (EC 5.1.1.7)	Staphylococcus haemolyticus JCSC1435 Gene: SH1512: Diaminopimelate epimerase alternative form predicted for S.aureus (EC 5.1.1.7)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1351: Diaminopimelate epimerase alternative form predicted for S.aureus (EC 5.1.1.7)	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1054: Diaminopimelate epimerase alternative form predicted for S.aureus (EC 5.1.1.7)	Diaminopimelate epimerase alternative form predicted for S.aureus (EC 5.1.1.7)
lysA	Staphylococcus aureus subsp. aureus N315 Gene: SA1232: Diaminopimelate decarboxylase (EC 4.1.1.20)	Staphylococcus capitis SK14 Gene: STACA0001_1646: Diaminopimelate decarboxylase (EC 4.1.1.20)	Staphylococcus epidermidis ATCC 12228 Gene: SE1080: Diaminopimelate decarboxylase (EC 4.1.1.20)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1044: Diaminopimelate decarboxylase (EC 4.1.1.20)	Staphylococcus haemolyticus JCSC1435 Gene: SH1511: Diaminopimelate decarboxylase (EC 4.1.1.20)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1350: Diaminopimelate decarboxylase (EC 4.1.1.20)	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1055: Diaminopimelate decarboxylase (EC 4.1.1.20)	Diaminopimelate decarboxylase (EC 4.1.1.20)

CRON 2.
lysP	* Staphylococcus aureus subsp. aureus N315 Site: position = -321 score = 112.83 sequence = AAATTGAGTTAGAGG... Gene: SA1505: Lysine-specific permease	* Staphylococcus capitis SK14 Site: position = -395 score = 113.15 sequence = TTAGAGTTAGAGGTT... Gene: STACA0001_2345: Lysine-specific permease	* Staphylococcus epidermidis ATCC 12228 Site: position = -382 score = 111.56 sequence = AAATAGAGTTAGAGG... Gene: SE1356: Lysine-specific permease	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -269 score = 105.87 sequence = AAAAAGTGTTAGAGG... Gene: Sca_1287: Lysine-specific permease	* Staphylococcus haemolyticus JCSC1435 Site: position = -334 score = 112.62 sequence = AAAGAGTTAGAGGTT... Gene: SH1244: Lysine-specific permease	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -383 score = 103.84 sequence = TTTGAGTTAGAGGTT... Gene: SSP1083: Lysine-specific permease	* Macrococcus caseolyticus JCSC5402 Site: position = -171 score = 101.62 sequence = TCGTTGAGGTAGAGG... Site: position = -171 score = 101.62 sequence = TCGTTGAGGTAGAGG... Gene: MCCL_1346: Lysine-specific permease	Lysine-specific permease

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Lysine - Staphylococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --