Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of PurR regulog to Geobacillus thermodenitrificans NG80-2

Reference regulog properties
Source regulog: PurR - Bacillales
Regulator type: Transcription factor
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Phylum: Firmicutes
Propagated regulon:
Target genome Geobacillus thermodenitrificans NG80-2
Orthologous TF(s) GTNG_0040
Regulated genes 6
Built upon 102 sites [see more]
Predicted regulatory interactions in Geobacillus thermodenitrificans NG80-2
Locus tag Position Score Sequence
Position: -281
Score: 8.8
Sequence: AAAAACGAATGAAA-(17)-GAATGTTCGTTTGT
Locus tag: GTNG_0234
GTNG_0234 -281 8.8 AAAAACGAATGAAA-(17)-GAATGTTCGTTTGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pbuG
Ortholog function: Hypoxanthine/guanine permease PbuG
Bacillus subtilis subsp. subtilis str. 168 BSU06370 -320 8.9 TATTACGAACAAAA-(16)-TATTGTTCGCTTTT
Bacillus amyloliquefaciens FZB42 RBAM_006790 -316 8.8 ATTAACGAATAAAC-(16)-GATTGTTCGTTTTT
Bacillus pumilus SAFR-032 BPUM_0592 -329 8.5 TAAGACGAATGAAG-(16)-AAATGTTCGCTTTT
Bacillus licheniformis DSM 13 BLi00688 -317 8.5 AACAACGAACGAAG-(16)-GAATGTTCGTTTTT
Anoxybacillus flavithermus WK1 Aflv_0226 -175 9.6 AAAAACGAACAAAA-(16)-AAATGTTCGTTATT
Geobacillus kaustophilus HTA426 GK0255 -292 9.6 AAAAACGAACAAAA-(17)-AAATGTTCGTCTTT
Bacillus cereus ATCC 14579 BC0297 -325 9.1 TAATACGAACGAAA-(16)-AAACGTTCGTTTTT
Oceanobacillus iheyensis HTE831 OB0723 -274 9.4 AAACACGAATGTTA-(16)-TTTTGTTCGTGTTT
Position: -307
Score: 9.3
Sequence: AAACACGAACATTC-(16)-GAATGTTCGATTTT
Locus tag: GTNG_0237
GTNG_0237 -307 9.3 AAACACGAACATTC-(16)-GAATGTTCGATTTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purE
Ortholog function: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Bacillus subtilis subsp. subtilis str. 168 BSU06420 -323 9 AAACACGAACATTA-(16)-TATCGTTCGATAAT
Bacillus amyloliquefaciens FZB42 RBAM_006840 -314 9 AAACACGAACATTA-(16)-TATCGTTCGATAAT
Bacillus pumilus SAFR-032 BPUM_0596 -352 8.6 AAATCCGAACATTA-(16)-GATTGTTCGATAAA
Bacillus licheniformis DSM 13 BLi00693 -319 8.9 AAACCCGAACATTA-(16)-TATCGTTCGATAAT
Anoxybacillus flavithermus WK1 Aflv_0228 -295 7.1 AAAATCCGAACATT-(17)-AAATGTTCGATTTT
-294 9.7 AAATCCGAACATTA-(16)-AAATGTTCGATTTT
Geobacillus kaustophilus HTA426 GK0257 -302 9.6 AAACACGAACATTT-(16)-AAATGTTCGATTTT
Bacillus cereus ATCC 14579 BC0323 -295 9 AAACACGAACGTTA-(16)-AAACATTCGATTAT
Bacillus halodurans C-125 BH0623 -353 9.4 AAAAACGAACATTG-(16)-TATTGTTCGAGTTT
Bacillus clausii KSM-K16 ABC1024 -470 6.8 AATGCCGAAAACAA-(16)-TTTGGTTCGTTGTT
-305 9 AAAAACGAACAATG-(16)-AAATGTTCGACTAT
Oceanobacillus iheyensis HTE831 OB0739 -360 8.7 AAACCCGAACGTTA-(16)-AATCATACGAGTTT
-342 7.3 AAAACTTTACAAAA-(17)-GATTTTTCGTATTT
Paenibacillus sp. JDR-2 Pjdr2_0860 -411 9.6 AAAAACGAACTTTA-(17)-TAATGTTCGTATTT
Position: -205
Score: 8.9
Sequence: AATGTCGAACATTA-(17)-AAAAGTTCGGTTTT
Locus tag: GTNG_1417
GTNG_1417 -205 8.9 AATGTCGAACATTA-(17)-AAAAGTTCGGTTTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: BH1470
Ortholog function: Uncharacterized FAD-dependent dehydrogenase
Anoxybacillus flavithermus WK1 Aflv_1375 -105 8.1 TAACACGAACATTA-(16)-AAAAGATCGCTTTT
Geobacillus kaustophilus HTA426 GK1569 -39 8.4 TATATCGAACATTT-(17)-GAAAGTTCGTGTTT
Bacillus halodurans C-125 BH1470 -119 8.9 AAAAACGAACATTA-(17)-CAATATTCGATTAA
Position: -61
Score: 8.2
Sequence: TTTTCCGAAAAATA-(17)-AAATGTTCGTGATT
Locus tag: GTNG_2328
GTNG_2328 -61 8.2 TTTTCCGAAAAATA-(17)-AAATGTTCGTGATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nusB
Ortholog function: Transcription termination factor
Bacillus subtilis subsp. subtilis str. 168 BSU24320 -149 9 AAATCCGAATAATC-(16)-AAATATTCGGTAAT
Bacillus amyloliquefaciens FZB42 RBAM_022650 -149 8.9 AAATCCGAATGAAA-(16)-AAATATTCGGCATT
Bacillus pumilus SAFR-032 BPUM_2164 -145 8.2 ATTTCCGAATCATA-(16)-AATGATTCGTTTTT
Bacillus licheniformis DSM 13 BLi02603 -152 9.5 AAAAACGAATGATA-(16)-TATTATTCGGTTAT
Geobacillus kaustophilus HTA426 GK2397 -63 8.4 TTTTCCGAAAAATA-(17)-GAATGTTCGTTTTT
Bacillus cereus ATCC 14579 BC4181 -219 6.7 AAAAACGTACATTG-(17)-TGAAGTTAATCTTT
Bacillus halodurans C-125 BH2785 -129 7.9 GAAAACGAAAGTTG-(17)-AATTGTTCTGTTTT
Position: -56
Score: 10.1
Sequence: AAAAACGAATATTA-(16)-TATTGTTCGTTTTT
Locus tag: GTNG_3355
GTNG_3355 -56 10.1 AAAAACGAATATTA-(16)-TATTGTTCGTTTTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pbuO
Ortholog function: Xanthine/uracil/thiamine/ascorbate permease family protein
Bacillus subtilis subsp. subtilis str. 168 BSU29990 -55 9.2 TAAAACGAATAATA-(17)-AAACGTTCGTAATT
Bacillus amyloliquefaciens FZB42 RBAM_027090 -55 9.2 TAAAACGAATAATA-(17)-AAATGTTCGTCATT
Bacillus pumilus SAFR-032 BPUM_2646 -55 9.1 TAAAACGAATATTA-(17)-TAATGTTCGTAAAT
Bacillus licheniformis DSM 13 BLi03152 -55 9.1 GATAACGAATAATA-(17)-TAATGTTCGTTATT
Position: -80
Score: 9.4
Sequence: ATAAACGAATAAAA-(17)-TAATGTTCGTGTTT
Locus tag: GTNG_3416
GTNG_3416 -80 9.4 ATAAACGAATAAAA-(17)-TAATGTTCGTGTTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purA
Ortholog function: Adenylosuccinate synthetase (EC 6.3.4.4)
Bacillus subtilis subsp. subtilis str. 168 BSU40420 -128 8.2 GGAAGCGAACGAAT-(17)-TAATGTTCGGATTT
Bacillus amyloliquefaciens FZB42 RBAM_037450 -132 8.6 TAAGGCGAACAAAC-(17)-AAATGTTCGGATTT
Bacillus pumilus SAFR-032 BPUM_3693 -128 9.3 TAAAACGAACAAAA-(16)-TAATGTTCGGCTTT
Bacillus licheniformis DSM 13 BLi04341 -130 9.5 AATAACGAACAAAA-(17)-TAATGTTCGGATTT
Anoxybacillus flavithermus WK1 Aflv_2841 -81 8.9 GTATACGAATAAAA-(17)-AAATGTTCGGTTTT
-68 6.9 AATAACAAACAAAC-(16)-TTTTATTGATTTTT
Geobacillus kaustophilus HTA426 GK3475 -113 9.4 ATAAACGAATAAAA-(17)-TAATGTTCGTGTTT
Bacillus cereus ATCC 14579 BC5468 -122 8 TCTTACGAACGAAA-(16)-AAATGTTCGCTTTT
Bacillus halodurans C-125 BH4028 -134 8.7 TGAACCGAACAAAT-(17)-AAATGTTCGGATTT
Bacillus clausii KSM-K16 ABC4100 -111 8.1 TTATACGAATGTTG-(16)-AAATGTTCGTGTCT
Oceanobacillus iheyensis HTE831 OB3453 -240 8.2 TCTTCCGTACATTA-(16)-AAATGTTCGTATTT
-62 6.7 TAATACGAATATAA-(17)-GTATATAATTAATT
Paenibacillus sp. JDR-2 Pjdr2_6258 -187 9.6 ATATCCGAACAATT-(16)-AATTGTTCGTTTTT