Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of AdcR regulog to Streptococcus pneumoniae R6

Reference regulog properties
Source regulog: AdcR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: MarR
Regulation mode: repressor
Biological process: Zinc homeostasis
Effector: Zinc ion, (Zn2+)
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pneumoniae R6
Orthologous TF(s) spr1978
Regulated genes 6
Built upon 72 sites [see more]
Predicted regulatory interactions in Streptococcus pneumoniae R6
Locus tag Position Score Sequence
Position: -18
Score: 5.1
Sequence: TATTTACTAGTTAATT
Position: -6
Score: 5
Sequence: AATTAAATGGTTAAGG
Locus tag: spr0906
spr0906 -18 5.1 TATTTACTAGTTAATT
-6 5 AATTAAATGGTTAAGG
Supported by regulated orthologs from reference regulons
Ortholog gene name: lmb3
Ortholog function: Laminin-binding surface lipoprotein
Streptococcus mitis B6 smi_1143 -24 5 AATTAAATAGTTAAGG
Streptococcus pneumoniae TIGR4 SP_1002 -36 5.1 TATTTACTAGTTAATT
Position: -104
Score: 5.1
Sequence: TATTTACTGGTTAATT
Locus tag: spr0908
spr0908 -104 5.1 TATTTACTGGTTAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: phtD2
Ortholog function: Histidine triad protein
Streptococcus gordonii str. Challis substr. CH1 SGO_1313 -98 5.2 AATAAACCAGTTAAGA
Streptococcus mitis B6 smi_1141 -106 5.1 TATTTACTGGTTAATT
Streptococcus pneumoniae TIGR4 SP_1004 -104 5.1 TATTTACTGGTTAATT
Streptococcus sanguinis SK36 SSA_1339 -46 5.5 TATTAACCAGTTAATA
-34 5.3 AATAAACCGGTTAATA
Position: -36
Score: 5.5
Sequence: TATTAACTAGTTAATT
Position: -24
Score: 5.3
Sequence: AATTAACCGGTTTATT
Locus tag: spr1060
spr1060 -36 5.5 TATTAACTAGTTAATT
-24 5.3 AATTAACCGGTTTATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: phtA
Ortholog function: Histidine triad protein
Streptococcus pneumoniae TIGR4 SP_1175 -126 5.4 TATTAACCAGTTAAGT
Streptococcus sanguinis SK36 SSA_1991 -164 5.3 GATTAACTGGTTAATT
Position: -49
Score: 5.4
Sequence: TATTAACCAGTTAAGT
Locus tag: spr1061
spr1061 -49 5.4 TATTAACCAGTTAAGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: phtA
Ortholog function: Histidine triad protein
Streptococcus pneumoniae TIGR4 SP_1175 -126 5.4 TATTAACCAGTTAAGT
Streptococcus sanguinis SK36 SSA_1991 -164 5.3 GATTAACTGGTTAATT
Position: -114
Score: 5.3
Sequence: ACTTTACTGGTAAATA
Locus tag: spr1866
spr1866 -114 5.3 ACTTTACTGGTAAATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhA2
Ortholog function: Alcohol dehydrogenase, zinc-containing
Streptococcus mitis B6 smi_0203 -114 5.2 ACTTTACCGGTAAATA
Streptococcus pneumoniae TIGR4 SP_2055 -114 5.3 ACTTTACTGGTAAATA
Position: -18
Score: 5.9
Sequence: AATTAACTGGTAAACA
Locus tag: spr1978
spr1978 -18 5.9 AATTAACTGGTAAACA
Supported by regulated orthologs from reference regulons
Ortholog gene name: adcR
Ortholog function: Zinc homeostasis trancsriptional regulator AdcR, MarR family
Streptococcus agalactiae 2603V/R SAG0154 -30 5.5 AATTTACTGGTTAACA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0126 -29 5.7 AATTAACTGGTTAATG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0103 -30 5.7 AATTAACTGGTTAATG
Streptococcus gallolyticus UCN34 GALLO_0079 -32 5.7 AATTAACTGGTTAATG
Streptococcus mutans UA159 SMU.1995c -32 5.9 AATTAACTGGTTAATT
Streptococcus pneumoniae TIGR4 SP_2172 -78 5.9 AATTAACTGGTAAACA
Streptococcus pyogenes M1 GAS SPy0092 -29 5.7 AATTAACTGGTTAATG
Streptococcus sanguinis SK36 SSA_0135 -45 5.6 AATTAACCAGTAAAGC
Streptococcus suis 05ZYH33 SSU05_0109 -30 5.4 ACTTAACAAGTTAATT
Streptococcus uberis 0140J SUB0110 -30 5.9 AATTAACTGGTTAAGA
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