Propagation of ArgR regulog to Streptococcus pyogenes MGAS5005
| Source regulog: | ArgR - Streptococcaceae |
| Regulator type: | Transcription factor |
| Regulator family: | ArgR |
| Regulation mode: | repressor, activator |
| Biological process: | Arginine biosynthesis; Arginine degradation |
| Effector: | Arginine |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Streptococcus pyogenes MGAS5005 |
| Orthologous TF(s) | M5005_Spy_1229, M5005_Spy_1807, M5005_Spy_1277 |
| Regulated genes | 6 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -58
Score: 5.5 Sequence: TTTGAATAATAATACAAT
Position: -16
Score: 5.1 Sequence: AAGGAATAAATATACTAT
Locus tag: M5005_Spy_0596
|
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| M5005_Spy_0596 | -58 | 5.5 | TTTGAATAATAATACAAT | |
| -16 | 5.1 | AAGGAATAAATATACTAT | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: artP | ||||
| Ortholog function: Arginine ABC transporter, substrate-binding protein | ||||
| Streptococcus agalactiae 2603V/R | SAG1431 | -54 | 4.2 | TATGTATAAAGATGATTT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0744 | -111 | 5 | TTTGAATAATAATGCACT |
| -69 | 5.1 | AAGGAATAAATATACTAT | ||
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0831 | -57 | 5.3 | ATTGAATAATAATGCAAT |
| -16 | 4.4 | AAGGAATAATTATAACAT | ||
| Streptococcus gallolyticus UCN34 | GALLO_1392 | -11 | 5.2 | AGAGAATAAATATGAAAA |
| Streptococcus pyogenes M1 GAS | SPy0778 | -58 | 5.5 | TTTGAATAATAATACAAT |
| -16 | 5.1 | AAGGAATAAATATACTAT | ||
| Streptococcus uberis 0140J | SUB0688 | -57 | 4.6 | ACGGTATAAAAATACATT |
| -16 | 4.7 | GGAGAATAAATATTCTAT | ||
| Streptococcus uberis 0140J | SUB0638 | -80 | 4.9 | TAGGTATAATTATTCATT |
| -50 | 4.7 | ATTGAATAATTATGTTAT | ||
|
Position: -72
Score: 4.5 Sequence: ATTGTATTAATATTCATC
Locus tag: M5005_Spy_1238
|
||||
| M5005_Spy_1238 | -72 | 4.5 | ATTGTATTAATATTCATC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: artQ | ||||
| Ortholog function: Arginine ABC transporter, permease protein | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1978 | -105 | 4.1 | AATTAATTTTTATACAAA |
| -63 | 4.7 | ATATTATAATTATGCTAT | ||
| -41 | 4.5 | TTTTTATAAAAATAGAAA | ||
| Lactococcus lactis subsp. lactis Il1403 | L38650 | -105 | 4.7 | AATTAATTATTATACATT |
| -63 | 4.7 | ATATTATAATTATGCTAT | ||
| -41 | 4.5 | TTTTTATAAAAATAGAAA | ||
| Streptococcus agalactiae 2603V/R | SAG0491 | -110 | 4.6 | TATATCTAAATATACAGT |
| -89 | 4.5 | ATAGAATAAAAACAAAAA | ||
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1495 | -72 | 4.9 | ATTGTATTAATATTCATT |
| -52 | 3.7 | ATGGTATAATTATCTTTA | ||
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0609 | -71 | 4.9 | ATTGTATCAATATTCATT |
| -51 | 4 | ATGGTATAATTATATCTA | ||
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0610 | -71 | 4.9 | ATTGTATCAATATTCATT |
| -51 | 4 | ATGGTATAATTATATCTA | ||
| Streptococcus mitis B6 | smi_0867 | -45 | 4 | ATGTTATAATCATACAGT |
| Streptococcus pneumoniae TIGR4 | SP_0823 | -38 | 4 | ATGTTATAATCATACAGT |
| Streptococcus pyogenes M1 GAS | SPy1507 | -72 | 4.5 | ATTGTATTAATATTCATC |
| -52 | 3.7 | ATGGTATAATTATCTTTA | ||
| Streptococcus suis 05ZYH33 | SSU05_0494 | -61 | 5.1 | ATTGCATAAATATTCAAA |
| Streptococcus suis 05ZYH33 | SSU05_0495 | -61 | 5.1 | ATTGCATAAATATTCAAA |
| Streptococcus thermophilus CNRZ1066 | str0605 | -70 | 4 | TTATAAGAAAAATACTTT |
| -57 | 4.1 | ACTTTATTATTATACAGT | ||
|
Position: -226
Score: 4.5 Sequence: AATTTATAAGTATAAATT
Position: -220
Score: 4.4 Sequence: TAAGTATAAATTTTTACA
Position: -167
Score: 4.8 Sequence: AATCTATAAAAATAAAAA
Locus tag: M5005_Spy_1275
|
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| M5005_Spy_1275 | -226 | 4.5 | AATTTATAAGTATAAATT | |
| -220 | 4.4 | TAAGTATAAATTTTTACA | ||
| -167 | 4.8 | AATCTATAAAAATAAAAA | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: arcA | ||||
| Ortholog function: Arginine deiminase (EC 3.5.3.6) | ||||
| Streptococcus agalactiae 2603V/R | SAG2163 | -162 | 4.5 | TTTCTATAAATTTAAATT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1548 | -227 | 4.5 | AATTTATAACTATAAATT |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0568 | -223 | 4.6 | AATTTATAAATATAAGAT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1593 | -221 | 4.1 | ATTTTATAAAAAAATAAA |
| Streptococcus pneumoniae TIGR4 | SP_2148 | -154 | 4.4 | TATGTATAATAACATAAA |
| Streptococcus pyogenes M1 GAS | SPy1547 | -226 | 4.5 | AATTTATAAGTATAAATT |
| -167 | 4.8 | AATCTATAAAAATAAAAA | ||
| Streptococcus sanguinis SK36 | SSA_0737 | -214 | 4.9 | AAAAAATAAATATTCACA |
| -148 | 4.5 | ATATTATAAAAATAGAAA | ||
| Streptococcus suis 05ZYH33 | SSU05_0624 | -174 | 4.7 | AAAAAATAAAAATTCATA |
| Streptococcus uberis 0140J | SUB1328 | -233 | 4.5 | AATTTATAACTATAAATT |
| -174 | 4.4 | TTTTTATAAAGATGCATT | ||
|
Position: -223
Score: 3.8 Sequence: ATTGATAAATTATACTGA
Position: -32
Score: 5.7 Sequence: AGAGGATAATTATACAAT
Locus tag: M5005_Spy_1807
|
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| M5005_Spy_1807 | -223 | 3.8 | ATTGATAAATTATACTGA | |
| -32 | 5.7 | AGAGGATAATTATACAAT | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: argR1 | ||||
| Ortholog function: Arginine metabolism transcriptional regulator ArgR, ArgR family | ||||
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_2093 | -32 | 5.7 | AGAGGATAATTATACAAT |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_1885 | -31 | 5.6 | AGAGGATAATTATACATT |
| Streptococcus gallolyticus UCN34 | GALLO_2201 | -31 | 5.4 | TAAGGATAAATATACACA |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_2057 | -31 | 5.5 | AGAGTATAAATATACAAC |
| Streptococcus mitis B6 | smi_0151 | -30 | 4.4 | TAGTTATAAATATGCATA |
| Streptococcus mutans UA159 | SMU.2093 | -172 | 4.6 | AAAGTATAAAAATCAATT |
| Streptococcus pneumoniae TIGR4 | SP_2077 | -30 | 3.9 | TAGTTATAAATATGCACG |
| Streptococcus pyogenes M1 GAS | SPy2150 | -32 | 5.7 | AGAGGATAATTATACAAT |
| Streptococcus suis 05ZYH33 | SSU05_2125 | -28 | 5.3 | TTTCTATAAATATACATT |
| Streptococcus uberis 0140J | SUB1788 | -32 | 5.7 | AGAGGATAATTATACAAT |
|
Position: -276
Score: 4.7 Sequence: ATTGTATAATTATCCTCT
Position: -85
Score: 4 Sequence: TCAGTATAATTTATCAAT
Position: -1
Score: 3.8 Sequence: TATGGATACTAAAACTCT
Locus tag: M5005_Spy_1808
|
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| M5005_Spy_1808 | -276 | 4.7 | ATTGTATAATTATCCTCT | |
| -85 | 4 | TCAGTATAATTTATCAAT | ||
| -1 | 3.8 | TATGGATACTAAAACTCT | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: argS | ||||
| Ortholog function: Arginyl-tRNA synthetase (EC 6.1.1.19) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_2323 | -69 | 4.7 | ATAGCATAATTATACCAT |
| Lactococcus lactis subsp. lactis Il1403 | L0344 | -69 | 4.7 | ATAGCATAATTATACCAT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_2094 | -274 | 4.7 | ATTGTATAATTATCCTCT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_2058 | -115 | 4.1 | GTTGTATATTTATACTCT |
| Streptococcus mitis B6 | smi_0150 | -105 | 4.2 | ATTTTATAACTATATTAT |
| Streptococcus mutans UA159 | SMU.2098 | -109 | 4 | AATGAATAAAATTTATTA |
| Streptococcus pneumoniae TIGR4 | SP_2078 | -117 | 3.9 | TATTTATAACTATATTTA |
| Streptococcus pyogenes M1 GAS | SPy2151 | -276 | 4.7 | ATTGTATAATTATCCTCT |
| Streptococcus suis 05ZYH33 | SSU05_2126 | -93 | 4.6 | AATGTATATTTATAGAAA |
| Streptococcus uberis 0140J | SUB1789 | -269 | 4.7 | ATTGTATAATTATCCTCT |