Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of PerR regulog to Streptococcus sanguinis SK36

Reference regulog properties
Source regulog: PerR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: FUR
Regulation mode: repressor
Biological process: Iron homeostasis; Manganese homeostasis; Oxidative stress response
Effector: Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus sanguinis SK36
Orthologous TF(s) SSA_0095, SSA_0686
Regulated genes 6
Built upon 75 sites [see more]
Predicted regulatory interactions in Streptococcus sanguinis SK36
Locus tag Position Score Sequence
Position: 21
Score: 4.7
Sequence: TTAGAATTTTTCCAA
Locus tag: SSA_0261
SSA_0261 21 4.7 TTAGAATTTTTCCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: mntB
Ortholog function: Manganese ABC transporter, permease protein
Streptococcus sanguinis SK36 SSA_0261 -54 4.4 TTATATTAATTTTAG
Position: -54
Score: 4.4
Sequence: TTATATTAATTTTAG
Locus tag: SSA_0262
SSA_0262 -54 4.4 TTATATTAATTTTAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: mntC
Ortholog function: Manganese ABC transporter, ATP-binding protein
Streptococcus agalactiae 2603V/R SAG1532 -28 5.1 TTATATTAATTTTAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0489 -124 5.6 TTATAATCATTATTA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1468 -124 5.6 TTATAATGATTATTA
Streptococcus gallolyticus UCN34 GALLO_2046 -66 4.8 TTATATTAAATATAA
Streptococcus mutans UA159 SMU.182 -26 4.8 TTATATTACTTATAA
Streptococcus pyogenes M1 GAS SPy0454 -124 5.6 TTATAATGATTATTA
Streptococcus sanguinis SK36 SSA_0262 -54 4.4 TTATATTAATTTTAG
Streptococcus uberis 0140J SUB0474 -123 5.6 TTATAATCATTATTA
Position: -227
Score: 5.9
Sequence: TTATAATCATTATAA
Locus tag: SSA_0299
SSA_0299 -227 5.9 TTATAATCATTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pcl
Ortholog function: Predicted membrane protein
Streptococcus agalactiae 2603V/R SAG0798 -79 5.9 TTAGAATGATTATAA
-57 5.4 TTGTAATCATTCTAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1772 -41 5.9 TTATAATGATTATAA
Streptococcus mutans UA159 SMU.635 -37 5.4 TTGTAATCATTCTAA
Streptococcus sanguinis SK36 SSA_0299 -227 5.9 TTATAATCATTATAA
Streptococcus thermophilus CNRZ1066 str0552 -65 4.9 TTGTAATCAATCTAA
-30 5.9 TTATAATGATTCTAA
Position: -83
Score: 5
Sequence: TTACAATCATTCTTA
Locus tag: SSA_0686
SSA_0686 -83 5 TTACAATCATTCTTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: perR
Ortholog function: Peroxide stress response transcriptional regulator PerR, Fur family
Streptococcus gordonii str. Challis substr. CH1 SGO_0703 -74 5 TTACAATCATTCTTA
Streptococcus mutans UA159 SMU.593 -157 4.7 TTTGAATGATTTTTA
Streptococcus sanguinis SK36 SSA_0686 -83 5 TTACAATCATTCTTA
Streptococcus suis 05ZYH33 SSU05_0310 -38 5.4 TTAGAATTTTTATAA
Streptococcus thermophilus CNRZ1066 str0724 -59 5.2 TTATAAATATTTTAA
Position: -68
Score: 4.7
Sequence: TTAGAAAAATTTTTA
Locus tag: SSA_1741
SSA_1741 -68 4.7 TTAGAAAAATTTTTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: fhuA
Ortholog function: Ferrichrome ABC transporter, ATP-binding protein
Streptococcus agalactiae 2603V/R SAG1392 -122 4.5 TTTGAATCATTCCAA
-37 4.6 TTATAATGAACTTAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0434 -229 4.6 CAAGAATGATTATTA
-207 4.5 TTTTAACCATTCTAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1618 -218 5.4 TGATAATGATTCTAA
Streptococcus gallolyticus UCN34 GALLO_1771 -180 4.8 TTAGAACAATTTTAA
-158 5.2 TTTGAATGATTCTAA
Streptococcus pyogenes M1 GAS SPy0386 -228 4.6 TTAGAATGATTATCG
-206 5.2 TTTTAATCATTCTAA
Streptococcus sanguinis SK36 SSA_1741 -68 4.7 TTAGAAAAATTTTTA
Streptococcus uberis 0140J SUB0424 -133 4.5 TTTTAACCATTCTAA
Position: -39
Score: 5
Sequence: TTAGAATAATTCTAG
Locus tag: SSA_1865
SSA_1865 -39 5 TTAGAATAATTCTAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: trxB
Ortholog function: Thioredoxin reductase (EC 1.8.1.9)
Streptococcus gordonii str. Challis substr. CH1 SGO_0581 -38 5.4 TTAGAATAATTATTA
Streptococcus sanguinis SK36 SSA_1865 -39 5 TTAGAATAATTCTAG
Streptococcus uberis 0140J SUB1412 -73 4.8 TTAAAATCATAATAA
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