Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of CcpA regulog to Lactococcus lactis subsp. cremoris SK11

Reference regulog properties
Source regulog: CcpA - Streptococcaceae
Regulator type: Transcription factor
Regulator family: LacI
Regulation mode:
Biological process: Global catabolite repression
Effector: Fructose-1,6-bisphosphate; HPr, phosphocarrier protein
Phylum: Firmicutes
Propagated regulon:
Target genome Lactococcus lactis subsp. cremoris SK11
Orthologous TF(s) LACR_1812
Regulated genes 44
Built upon 968 sites [see more]
Predicted regulatory interactions in Lactococcus lactis subsp. cremoris SK11
Locus tag Position Score Sequence
Position: 0
Score: 4.2
Sequence: ATGAAATTGCTTTTAA
Locus tag: LACR_C06
LACR_C06 0 4.2 ATGAAATTGCTTTTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pabA
Ortholog function: Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) # PabAb
Lactococcus lactis subsp. cremoris SK11 LACR_C06 0 4.2 ATGAAATTGCTTTTAA
Position: -134
Score: 4.9
Sequence: ATGAAAACGTTATCTT
Locus tag: LACR_D06
LACR_D06 -134 4.9 ATGAAAACGTTATCTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: lacA1
Ortholog function: Galactose-6-phosphate isomerase, LacA subunit (EC 5.3.1.26)
Streptococcus gordonii str. Challis substr. CH1 SGO_1526 -54 4.4 AAGAAAGCGTTTTACT
Position: -52
Score: 4.1
Sequence: TTGGTAGCGGTTACAA
Locus tag: LACR_0027
LACR_0027 -52 4.1 TTGGTAGCGGTTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: mtlA
Ortholog function: Mannitol-specific PTS system, IIBC component (EC 2.7.1.69)
Lactococcus lactis subsp. cremoris SK11 LACR_0027 -52 4.1 TTGGTAGCGGTTACAA
Streptococcus gallolyticus UCN34 GALLO_0993 -57 4.4 TGTAAAACGCTTACAT
Streptococcus pneumoniae TIGR4 SP_0394 -55 4 TTTTAAAGGTTTTTAA
Streptococcus uberis 0140J SUB0997 -54 4.3 ATGTCAGCGTTTCCAT
Position: -89
Score: 4.4
Sequence: ATGTAAAAGCTTACAA
Locus tag: LACR_0030
LACR_0030 -89 4.4 ATGTAAAAGCTTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: mtlD
Ortholog function: Mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17)
Lactococcus lactis subsp. cremoris SK11 LACR_0030 -89 4.4 ATGTAAAAGCTTACAA
Lactococcus lactis subsp. lactis Il1403 L33416 -88 4.4 ATGTAAAAGCTTACAA
Streptococcus gallolyticus UCN34 GALLO_0996 -57 4.4 TGTAAAACGCTTACAT
Streptococcus pneumoniae TIGR4 SP_0397 -55 4 TTTTAAAGGTTTTTAA
Streptococcus uberis 0140J SUB0994 -54 4.3 ATGTCAGCGTTTCCAT
Position: -115
Score: 4.1
Sequence: TGTTAAACGGTTTCAT
Locus tag: LACR_0133
LACR_0133 -115 4.1 TGTTAAACGGTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: yscN
Ortholog function: Predicted oxidoreductase, aldo/keto reductase family
Lactococcus lactis subsp. cremoris SK11 LACR_0133 -115 4.1 TGTTAAACGGTTTCAT
Streptococcus agalactiae 2603V/R SAG1681 -82 4.6 TAGTAAGCCTTTTCAT
Streptococcus suis 05ZYH33 SSU05_2143 -28 4.3 TGAAAAGCGTTTACAA
Streptococcus uberis 0140J SUB1533 -59 4.3 CGGAAATCGTTTTCAA
Position: -171
Score: 3.8
Sequence: ATGAAAATATTTTTAA
Locus tag: LACR_0396
LACR_0396 -171 3.8 ATGAAAATATTTTTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: rheA
Ortholog function: Cold-shock DEAD-box protein A
Streptococcus agalactiae 2603V/R SAG0777 -142 4.2 ATGAAAGCGTGTTATT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1455 -146 4.2 ATGAAAACGTGTTATT
-53 4 ATTAAAAGGTTTATAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0646 -135 4.5 ATAAAAACACTTTCAT
-53 4 ATTAAAAGGTTTATAA
Streptococcus gallolyticus UCN34 GALLO_0655 -139 4.2 ATGAAAACGTGTTATT
-116 3.9 ATGAAACTGTTTCCTA
Streptococcus mutans UA159 SMU.611 -127 3.9 TTGAAAACGATCATTT
Streptococcus pyogenes M1 GAS SPy1415 -199 3.7 CAAAAAACGATATCTT
-53 4 ATTAAAAGGTTTATAA
Streptococcus suis 05ZYH33 SSU05_1574 -166 4.4 ATGAAAACGTATTATT
Streptococcus uberis 0140J SUB1250 -70 4.5 ATAAAAACCTTTTCAT
Position: -50
Score: 4.6
Sequence: CAGAAAACGTTTTAAT
Locus tag: LACR_0408
LACR_0408 -50 4.6 CAGAAAACGTTTTAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: yjbM
Ortholog function: GTP pyrophosphokinase (EC 2.7.6.5)
Lactococcus lactis subsp. cremoris SK11 LACR_0408 -50 4.6 CAGAAAACGTTTTAAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1045 -120 4.1 TTGTATTCGATTTCTA
Streptococcus gordonii str. Challis substr. CH1 SGO_1222 -82 4.3 TTGAAAACGATTTATG
Streptococcus mitis B6 smi_1182 -106 4.2 ATGAAAGCGGATTATA
Streptococcus pneumoniae TIGR4 SP_1097 -106 4.3 TTGAAAGCGGATTTAT
Streptococcus sanguinis SK36 SSA_1210 -74 4.3 TTGAAAGCGATTTATG
Streptococcus suis 05ZYH33 SSU05_1060 -85 4.2 CAGTAAACCCTTTCAA
Position: -69
Score: 4.7
Sequence: ATAAAAACGTTTTCAG
Locus tag: LACR_0480
LACR_0480 -69 4.7 ATAAAAACGTTTTCAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: treR
Ortholog function: Trehalose utilization transcriptional regulator TreR, GntR family
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_2070 -115 4.3 TTGTAATCGATTGCAA
Streptococcus gallolyticus UCN34 GALLO_2176 -129 4.4 TTGTAATCGTTTTCCA
Streptococcus gordonii str. Challis substr. CH1 SGO_1654 -106 4.1 TTGTAAACGATACCAA
Streptococcus mutans UA159 SMU.2040 -112 4.8 TTGTAAACGATTACAA
Streptococcus pneumoniae TIGR4 SP_1885 -137 4.1 TTGTAAACGATACCAA
Streptococcus pyogenes M1 GAS SPy2099 -115 4.3 TTGTAATCGATTGCAA
Streptococcus sanguinis SK36 SSA_1753 -104 4.3 TTGTAATCGATTCCAA
Streptococcus suis 05ZYH33 SSU05_0232 -118 4.2 TTGTATCCGATTTCAA
Streptococcus uberis 0140J SUB1764 -117 4.3 TTGTAATCGATTCCAA
Position: -133
Score: 4.4
Sequence: ATGAAAGCTGTTTCAT
Locus tag: LACR_0667
LACR_0667 -133 4.4 ATGAAAGCTGTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: raiA
Ortholog function: Ribosome-associated protein Y
Lactococcus lactis subsp. cremoris SK11 LACR_0667 -133 4.4 ATGAAAGCTGTTTCAT
Lactococcus lactis subsp. lactis Il1403 L32389 -133 4.4 ATGAAAGCTGTTTCAT
Streptococcus agalactiae 2603V/R SAG0338 -60 4.6 ATGAAAGCGGTTATAA
-36 4.7 TAGAAAGCGTTAACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1681 -64 4.5 ATGAAAGCGGTATAAT
-35 4.2 AAGAAAGCGCTTCAAG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1545 -36 4.9 AAGAAAGCGTTTTAAA
Streptococcus gallolyticus UCN34 GALLO_0504 -59 3.8 ATGAAAGCAGTATAAT
-34 4.8 AAGAAAGCGCTTTATA
Streptococcus gordonii str. Challis substr. CH1 SGO_0610 -63 4.7 ATGAAAGCGTTATAAT
Streptococcus mitis B6 smi_2056 -57 4.7 ATGAAAGCGTTATAAT
Streptococcus mutans UA159 SMU.500 -58 4.5 ATGAAAGCGATATAAT
Streptococcus pneumoniae TIGR4 SP_2206 -57 4.7 ATGAAAGCGTTATAAT
Streptococcus pyogenes M1 GAS SPy1613 -64 3.8 ATGAAAGCAGTATAAT
-35 4 AAGTAAGCGCTTCAAG
Streptococcus sanguinis SK36 SSA_1834 -60 4.7 ATGAAAGCGTTATAAT
Streptococcus suis 05ZYH33 SSU05_0439 -42 4.5 AAGAAAACGGTTGCAA
Streptococcus thermophilus CNRZ1066 str0370 -57 3.9 ATGAAAAGGATATAAT
-34 4.7 AAGAAAACGCTAACAA
Streptococcus uberis 0140J SUB1375 -59 4.4 ATGAAAACGGTATAAT
Position: -156
Score: 5.1
Sequence: ATGAAAACGTTTTAAA
Locus tag: LACR_0691
LACR_0691 -156 5.1 ATGAAAACGTTTTAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pfl
Ortholog function: Pyruvate formate-lyase (EC 2.3.1.54)
Lactococcus lactis subsp. cremoris SK11 LACR_0691 -156 5.1 ATGAAAACGTTTTAAA
Lactococcus lactis subsp. lactis Il1403 L57408 -156 5.1 ATGAAAACGTTTTAAA
Streptococcus gallolyticus UCN34 GALLO_1953 -82 4.2 TGGAAAACGCTTCCTT
Streptococcus gordonii str. Challis substr. CH1 SGO_0247 -115 4.6 AAGAAAAGGCTTACAA
-83 4.1 GTGTAAACGATTACTA
Streptococcus mitis B6 smi_1815 -82 4.2 TTGAAATCGGTTACTG
Streptococcus mutans UA159 SMU.402 -113 4.9 AAGAAATCGCTTACAA
Streptococcus pneumoniae TIGR4 SP_0459 -78 4.5 TTGAAATCGGTTACTA
Streptococcus suis 05ZYH33 SSU05_0200 -124 4.1 TTGAAAGGTTTTTCAT
-84 4.6 TAGAAAGTGTTTTCAA
Streptococcus thermophilus CNRZ1066 str1657 -93 4.4 ATGTAAGCGGTTACTG
Position: -61
Score: 5.1
Sequence: AAGAAAACGTTTTCTT
Locus tag: LACR_0723
LACR_0723 -61 5.1 AAGAAAACGTTTTCTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: malQ
Ortholog function: 4-alpha-glucanotransferase (amylomaltase) (EC 2.4.1.25)
Lactococcus lactis subsp. cremoris SK11 LACR_0723 -61 5.1 AAGAAAACGTTTTCTT
Lactococcus lactis subsp. lactis Il1403 L93919 -56 5.1 AAGAAAACGTTTTCTT
Lactococcus lactis subsp. lactis Il1403 L94405 -56 5.1 AAGAAAACGTTTTCTT
Position: -25
Score: 4.2
Sequence: TTGTAAACGAATTCAG
Locus tag: LACR_1031
LACR_1031 -25 4.2 TTGTAAACGAATTCAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: fruR
Ortholog function: Fructose utilization transcriptional regulator FruR, DeoR family
Lactococcus lactis subsp. cremoris SK11 LACR_1031 -25 4.2 TTGTAAACGAATTCAG
Lactococcus lactis subsp. lactis Il1403 L0031 -25 4.2 TTGTAAACGAATTCAG
Streptococcus agalactiae 2603V/R SAG1348 -30 4.7 TTGCAAACGATTTCAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0811 -60 4.1 CTGTAACCGATTTCAG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1106 -62 4.4 CTGTAAACGATTTCAG
Streptococcus gallolyticus UCN34 GALLO_1319 -30 4.4 CTGTAAACGATTTCAG
Streptococcus gordonii str. Challis substr. CH1 SGO_1111 -27 4 ATGTAAGCTGTTTCAG
Streptococcus mutans UA159 SMU.870 22 4.4 GTGTAAACGATTTCAA
Streptococcus pyogenes M1 GAS SPy0853 -60 4.7 TTGTAAACGATTTCAG
Streptococcus suis 05ZYH33 SSU05_0822 14 4.2 TTGTAAACGGTTGCAG
Streptococcus thermophilus CNRZ1066 str0399 -109 3.8 AGGTTAGCGTTTTATA
-27 4.5 TTGTAAACGATTACAG
Streptococcus uberis 0140J SUB0748 -60 4.4 TTGTAACCGATTTCAG
Position: -28
Score: 4.3
Sequence: ATAAATACGCTTTCAG
Locus tag: LACR_1054
LACR_1054 -28 4.3 ATAAATACGCTTTCAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: fdhC
Ortholog function: Predicted formate transporter
Lactococcus lactis subsp. cremoris SK11 LACR_1054 -28 4.3 ATAAATACGCTTTCAG
Lactococcus lactis subsp. lactis Il1403 L195318 -29 4.3 ATAAATACGCTTTCAG
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1466 -51 4 ATGGAAGGGCTTGCAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0639 -51 4.1 CTGAAAGTGCTTGCAT
Streptococcus pyogenes M1 GAS SPy1424 -78 4.4 TTGAAAGGGCTTGCAT
Streptococcus uberis 0140J SUB1260 -78 4 ATGGAAGGGCTTGCAT
Position: -70
Score: 4.2
Sequence: ATGTAAGCGTATGCTA
Locus tag: LACR_1356
LACR_1356 -70 4.2 ATGTAAGCGTATGCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: nanE
Ortholog function: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Streptococcus agalactiae 2603V/R SAG0033 -74 5.1 TTGAAAACGCTTTAAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0245 -142 4.6 CTGAATACGTTTTCAA
-72 5.1 TTGAAAACGCTTTAAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0241 -72 4.5 TTGAAAGTGTTTTAAT
Streptococcus gordonii str. Challis substr. CH1 SGO_0118 -76 5.1 TTGAAAGCGCTTTAAT
Streptococcus mitis B6 smi_0602 -63 4.5 TTGAAAGCGCTTCATA
Streptococcus pneumoniae TIGR4 SP_1685 -63 5.1 TTGAAAGCGTTTTAAT
Streptococcus sanguinis SK36 SSA_0071 -181 5.1 TTGAAAGCGCTTTAAA
Streptococcus suis 05ZYH33 SSU05_1402 -43 4.1 ATGTAAGCGCTATCTC
Streptococcus uberis 0140J SUB1658 -76 4.9 TTGAAAACGCTTTATT
Position: -350
Score: 3.9
Sequence: ATGAAAATAATTTCAA
Position: -184
Score: 4.2
Sequence: TAGAAAACCCTTGCAA
Position: -143
Score: 4.4
Sequence: ATGAAAACGTTTCATA
Position: -55
Score: 3.8
Sequence: TTAATAACGTTTACGT
Locus tag: LACR_1457
LACR_1457 -350 3.9 ATGAAAATAATTTCAA
-184 4.2 TAGAAAACCCTTGCAA
-143 4.4 ATGAAAACGTTTCATA
-55 3.8 TTAATAACGTTTACGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pfk
Ortholog function: 6-phosphofructokinase (EC 2.7.1.11)
Lactococcus lactis subsp. cremoris SK11 LACR_1457 -184 4.2 TAGAAAACCCTTGCAA
-143 4.4 ATGAAAACGTTTCATA
Lactococcus lactis subsp. lactis Il1403 L0002 -184 4.2 TAGAAAACCCTTGCAA
-143 4.4 ATGAAAACGTTTCATA
Streptococcus agalactiae 2603V/R SAG0940 -37 3.8 ATTAAATCGTTAAATT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1095 -100 3.9 TTGAAAACGGTTTTTC
-36 4 ATAAAAACGTTAAATT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0881 -100 3.9 TTGAAAACGGTTTTTC
-36 4 ATAAAAACGTTAAATT
Streptococcus gallolyticus UCN34 GALLO_0989 -135 4.3 ATTGAAGCGCTATCAA
-111 4 TTGAAAACGATTTATC
Streptococcus gordonii str. Challis substr. CH1 SGO_1340 -92 4.1 ATGAAAACGATTTATC
Streptococcus mitis B6 smi_1004 -102 4.1 ATGAAAACGATTTATC
Streptococcus mutans UA159 SMU.1191 -103 3.9 CTGAAAACGCTTTTTC
Streptococcus pneumoniae TIGR4 SP_0896 -102 4.1 ATGAAAACGATTTATC
Streptococcus sanguinis SK36 SSA_0847 -105 4 ATGAAAACGATTTTTC
Streptococcus suis 05ZYH33 SSU05_0543 -147 3.9 ATGAAAACGCCTCAAT
-105 4 ATGAAAACGATTTTTC
Streptococcus thermophilus CNRZ1066 str1197 -67 4.1 TTGAAAACGGTTTTAC
Streptococcus uberis 0140J SUB1001 -36 4.1 ATTAAAACGTTAAATT
Position: -68
Score: 4.1
Sequence: TTTAATACGCTTACAG
Locus tag: LACR_1533
LACR_1533 -68 4.1 TTTAATACGCTTACAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: coaA
Ortholog function: Pantothenate kinase (EC 2.7.1.33)
Lactococcus lactis subsp. cremoris SK11 LACR_1533 -68 4.1 TTTAATACGCTTACAG
Lactococcus lactis subsp. lactis Il1403 L66222 -68 4.1 TTTAATACGCTTACAG
Streptococcus agalactiae 2603V/R SAG0951 -60 4.5 TTGAAACGGTTTTCAA
-29 3.9 TTATAATAGCTTTCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1052 -199 3.9 TTTTAAAGGTTTCCAA
-32 4.2 ATGTAAGCACTGTCAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0931 -223 4.4 TTGAAATGGTTTACAA
Streptococcus gallolyticus UCN34 GALLO_1139 -69 4.4 TTGTAACGGTTTTCAA
-47 3.8 ATTAAAGTGCTATAAT
Streptococcus gordonii str. Challis substr. CH1 SGO_1077 -74 4.1 TGTAAATCGTTTACAT
Streptococcus mitis B6 smi_0883 -64 4.5 AAGAAACCGCTTTATT
Streptococcus mutans UA159 SMU.1126 -52 4.5 TTGAAACGGTTTTCAA
Streptococcus pneumoniae TIGR4 SP_0839 -64 4.5 AAGAAACCGCTTTATT
Streptococcus pyogenes M1 GAS SPy1233 -223 4.4 TTGAAATGGTTTACAA
-32 4.2 ATGTAAGCACTGTCAA
Streptococcus sanguinis SK36 SSA_1033 -64 4.3 TGTAAATCGTTTTCAT
Streptococcus suis 05ZYH33 SSU05_1088 -89 4.7 CTAAAAACGTTTTCAA
-32 4 ATTGAAACGCTTACCT
Streptococcus thermophilus CNRZ1066 str0799 -45 4.3 TTGATAAGGCTTACAT
Streptococcus uberis 0140J SUB0955 -219 4.4 TTGAAATGGTTTACAA
Position: -62
Score: 4
Sequence: ATGAAAACCGTTTTTA
Locus tag: LACR_1734
LACR_1734 -62 4 ATGAAAACCGTTTTTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: tkt
Ortholog function: Transketolase (EC 2.2.1.1)
Lactococcus lactis subsp. cremoris SK11 LACR_1734 -62 4 ATGAAAACCGTTTTTA
Lactococcus lactis subsp. lactis Il1403 L0043 -62 4.4 ATGAAAACCGTTTCTA
Position: -64
Score: 4.5
Sequence: ATGAAAACGGATACAA
Locus tag: LACR_1803
LACR_1803 -64 4.5 ATGAAAACGGATACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: rbsR
Ortholog function: Ribose utilization transcriptional regulator, LacI family
Lactococcus lactis subsp. cremoris SK11 LACR_1803 -64 4.5 ATGAAAACGGATACAA
Lactococcus lactis subsp. lactis Il1403 L0145 -64 4.5 ATGAAAACGGATACAA
Streptococcus agalactiae 2603V/R SAG0119 -60 4.7 TAGTAAGCGATTACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1537 -65 4.8 AAGAAAACGGTTACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0468 -60 4.8 TAGAAAACGGTTACAA
Streptococcus uberis 0140J SUB1312 -45 4.8 AAGAAAACGGTTACAA
Position: -93
Score: 4.4
Sequence: TTGAAAAGGTTTACAG
Locus tag: LACR_1812
LACR_1812 -93 4.4 TTGAAAAGGTTTACAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: ccpA
Ortholog function: Carbon catabolism global transcriptional regulator CcpA, LacI family
Lactococcus lactis subsp. cremoris SK11 LACR_1812 -93 4.4 TTGAAAAGGTTTACAG
Lactococcus lactis subsp. lactis Il1403 L0143 -93 4.4 TTGAAAAGGTTTACAG
-57 4.1 TAAAAATGGTTTTCAT
Streptococcus agalactiae 2603V/R SAG0707 -74 4.3 TTGAAAGTGTTTCCAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0545 -105 4.6 TTGAAAACTTTTTCAA
-72 4.3 TTGAAAGTGGTTACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1410 -105 4.6 TTGAAAACTTTTTCAA
-72 4.3 TTGAAAGTGGTTACAA
Streptococcus gallolyticus UCN34 GALLO_1582 -122 4.7 AATTAAACGCTTACAA
-71 4.3 TTGAAAGTGTTTCCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0773 -82 4.3 TTGAAAGTGTTTCCAA
-38 4.5 ATGAAAACGTTATTTT
Streptococcus mitis B6 smi_0284 -113 4.6 TTGAAAGTGTTTACAA
Streptococcus mutans UA159 SMU.1591 -72 4.8 TTGAAAGTGTTTTCAA
Streptococcus pneumoniae TIGR4 SP_1999 -150 4.6 TTGAAAGTGTTTACAA
Streptococcus pyogenes M1 GAS SPy0514 -105 4.6 TTGAAAACTTTTTCAA
-72 4.3 TTGAAAGTGGTTACAA
Streptococcus sanguinis SK36 SSA_1576 -81 4.6 TTGAAAGTGTTTACAA
Streptococcus thermophilus CNRZ1066 str0630 -41 4.8 TTGAAAGTGTTTTCAA
Streptococcus uberis 0140J SUB0536 -72 4.5 TTGAAAGTGGTTTCAA
Position: -136
Score: 4.4
Sequence: CTGTAAACCTTTTCAA
Locus tag: LACR_1813
LACR_1813 -136 4.4 CTGTAAACCTTTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pepQ
Ortholog function: Xaa-Pro dipeptidase (EC 3.4.13.9)
Lactococcus lactis subsp. cremoris SK11 LACR_1813 -136 4.4 CTGTAAACCTTTTCAA
Lactococcus lactis subsp. lactis Il1403 L96847 -173 4.1 ATGAAAACCATTTTTA
-137 4.4 CTGTAAACCTTTTCAA
Streptococcus agalactiae 2603V/R SAG0706 -151 4.3 TTGGAAACACTTTCAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0544 -151 4 AAAATTACGCTTTCAA
-117 4.3 TTGTAACCACTTTCAA
-84 4.6 TTGAAAAAGTTTTCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0771 -142 4.5 AAAATAACGTTTTCAT
-98 4.3 TTGGAAACACTTTCAA
Streptococcus mutans UA159 SMU.1592 -106 4.8 TTGAAAACACTTTCAA
Streptococcus pyogenes M1 GAS SPy0513 -117 4.3 TTGTAACCACTTTCAA
-84 4.6 TTGAAAAAGTTTTCAA
Streptococcus sanguinis SK36 SSA_1577 -97 4.6 TTGTAAACACTTTCAA
Streptococcus suis 05ZYH33 SSU05_1373 -135 4.5 TTGAAACCACTTTCAA
Streptococcus thermophilus CNRZ1066 str0629 -134 3.8 TATTCATCGCTTACAA
Streptococcus uberis 0140J SUB0535 -115 4.5 TTGAAACCACTTTCAA
Position: -94
Score: 4.2
Sequence: ATGTGAACGCTTAAAA
Position: 3
Score: 4
Sequence: AAGAAAACGTTGATTA
Locus tag: LACR_1825
LACR_1825 -94 4.2 ATGTGAACGCTTAAAA
3 4 AAGAAAACGTTGATTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: udk
Ortholog function: Uridine kinase (EC 2.7.1.48) [C1]
Lactococcus lactis subsp. cremoris SK11 LACR_1825 -94 4.2 ATGTGAACGCTTAAAA
Lactococcus lactis subsp. lactis Il1403 L108994 -95 4.2 ATGTGAACGCTTAAAA
Streptococcus agalactiae 2603V/R SAG0826 -88 4.5 TTTAGAGCGTTTTCAA
Streptococcus gallolyticus UCN34 GALLO_0750 -79 4.1 AAGTAAGAGTTTTCAG
Position: -224
Score: 4.1
Sequence: AATAAAGCCCTTTAAA
Position: -171
Score: 4.3
Sequence: ATGAAAGCGTTATGAT
Locus tag: LACR_1852
LACR_1852 -224 4.1 AATAAAGCCCTTTAAA
-171 4.3 ATGAAAGCGTTATGAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: dexC
Ortholog function: Neopullulanase (EC 3.2.1.135)
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1304 -178 4.2 TTGTAAGCGATTACGA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1265 -190 4.3 CTGTAAGCGATTGCAT
Streptococcus pyogenes M1 GAS SPy1304 -163 4.3 ATGAAAGCGATTACGA
Position: -216
Score: 4.3
Sequence: ATCATAACGCTTTCAT
Position: -163
Score: 4.1
Sequence: TTTAAAGGGCTTTATT
Position: -32
Score: 4.7
Sequence: AATAAACCGTTTTCAT
Locus tag: LACR_1853
LACR_1853 -216 4.3 ATCATAACGCTTTCAT
-163 4.1 TTTAAAGGGCTTTATT
-32 4.7 AATAAACCGTTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: malE
Ortholog function: Maltose/maltodextrin ABC transporter, substrate-binding protein
Lactococcus lactis subsp. cremoris SK11 LACR_1853 -163 4.1 TTTAAAGGGCTTTATT
-32 4.7 AATAAACCGTTTTCAT
Lactococcus lactis subsp. lactis Il1403 L128695 -32 4.7 AATAAACCGTTTTCAT
Streptococcus agalactiae 2603V/R SAG1441 -58 4.2 TTGCAAACGGTTGCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1296 -56 3.9 CTGCAAGCGGTTGCAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1257 -56 3.9 CTGCAAGCGGTTGCAT
Streptococcus gallolyticus UCN34 GALLO_1399 -156 4.7 ATGAAATCGCTTAAAT
-66 3.9 CTGCAAACGGTTGCAT
Streptococcus mutans UA159 SMU.1568 -189 3.8 TTGTTAACCTTTTATA
Streptococcus pyogenes M1 GAS SPy1294 -56 3.9 CTGCAAGCGGTTGCAT
Streptococcus sanguinis SK36 SSA_1298 -200 4.8 AATAAAGCGCTTTCTA
-54 4.2 TTGCAAACGGTTGCAT
Streptococcus uberis 0140J SUB1143 -53 3.9 CTGCAAACGGTTGCAT
Position: -87
Score: 4.3
Sequence: ATGAAAACATTTGCAA
Locus tag: LACR_1863
LACR_1863 -87 4.3 ATGAAAACATTTGCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: manL
Ortholog function: PTS system, mannose-specific IIAB components
Lactococcus lactis subsp. cremoris SK11 LACR_1863 -87 4.3 ATGAAAACATTTGCAA
Lactococcus lactis subsp. lactis Il1403 L1762179 -87 4.3 ATGAAAACATTTGCAA
Streptococcus agalactiae 2603V/R SAG0361 -130 4.7 CTGAAAACGTTTTAAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1806 -131 4.4 GTGAAAACGTTTTAAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0423 -131 4.4 GTGAAAACGTTTTAAA
Streptococcus gallolyticus UCN34 GALLO_0350 -128 4.5 TTGAAAACGTTTTACA
Streptococcus gordonii str. Challis substr. CH1 SGO_1679 -80 4.6 CTGAAAACGTTTTATA
Streptococcus mitis B6 smi_0274 -124 4.2 ATTTAAATGTTTTCTT
-77 4.6 ATGAAAACGGTTTATA
Streptococcus mutans UA159 SMU.1877 -105 4.4 ATGTAAACGTTTTACA
Streptococcus pneumoniae TIGR4 SP_0284 -68 4.6 ATGAAAACGGTTTATA
Streptococcus pyogenes M1 GAS SPy1738 -131 4.4 GTGAAAACGTTTTAAA
Streptococcus sanguinis SK36 SSA_1918 -71 4.9 ATGAAAACGTTTTATA
Streptococcus suis 05ZYH33 SSU05_1778 -91 4.2 CTGTAATCGTTTTATA
-59 4.4 ATGAAAGCCCATTCAA
Streptococcus thermophilus CNRZ1066 str0333 -139 4.5 ATGATAACGCTTTATA
Streptococcus uberis 0140J SUB1482 -130 5 TTGAAAACGTTTTAAA
Position: -135
Score: 4.3
Sequence: TATCAAACGCTTACAA
Locus tag: LACR_1939
LACR_1939 -135 4.3 TATCAAACGCTTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: atpE
Ortholog function: ATP synthase C chain (EC 3.6.3.14)
Lactococcus lactis subsp. cremoris SK11 LACR_1939 -135 4.3 TATCAAACGCTTACAA
Lactococcus lactis subsp. lactis Il1403 L11729a -135 4.2 CTTCAAACGCTTACAA
Streptococcus agalactiae 2603V/R SAG0857 -93 4.5 ATGAAAACGTAATCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1548 -96 4.6 TTAAAATCGCTTACAA
Streptococcus mitis B6 smi_1315 -93 4.5 CATTAAACGCTTTCAA
Streptococcus mutans UA159 SMU.1534 -161 4.1 TTAAAAGCGTCTTCTA
Streptococcus sanguinis SK36 SSA_0782 -194 4.5 TTTTAATCGCTTTCTT
-95 4.4 CAAAAAACGCTTACAA
Streptococcus suis 05ZYH33 SSU05_1178 -92 4.7 AATTAAACGCTTACAA
Streptococcus uberis 0140J SUB0666 -94 4.4 AAGAAAGCGTAATCAA
Position: -44
Score: 4.6
Sequence: AAGAATGCGTTTACAA
Locus tag: LACR_1990
LACR_1990 -44 4.6 AAGAATGCGTTTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhB1
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1)
Lactococcus lactis subsp. cremoris SK11 LACR_1990 -44 4.6 AAGAATGCGTTTACAA
Lactococcus lactis subsp. lactis Il1403 L55758 -43 5.1 AAGAAAGCGTTTACAA
Streptococcus agalactiae 2603V/R SAG0054 -49 4.9 ATGTAAACGATTACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0062 -52 4.5 TTGTAAACGGTTACAG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0046 -56 4.5 TTGTAAACGGTTGCAA
Streptococcus mitis B6 smi_0275 -130 4.1 TGGAAAAGGCTTTCTT
Streptococcus pneumoniae TIGR4 SP_0285 -130 4.1 TGGAAAAGGCTTTCTT
Streptococcus pyogenes M1 GAS SPy0044 -44 4.6 TTGTAACCGATTACAA
Streptococcus sanguinis SK36 SSA_1917 -78 4.6 TTGTAAACGTTTCCTA
Streptococcus suis 05ZYH33 SSU05_0279 -197 4.8 AAGAAAACGCTTCCAT
Streptococcus thermophilus CNRZ1066 str0880 -50 4.3 ATGTAAGCGTTGATAT
Streptococcus thermophilus CNRZ1066 str0881 -50 4.3 ATGTAAGCGTTGATAT
Streptococcus thermophilus CNRZ1066 str0882 -50 4.3 ATGTAAGCGTTGATAT
Position: -100
Score: 4.4
Sequence: AATAAAGCGGTTACTT
Locus tag: LACR_2168
LACR_2168 -100 4.4 AATAAAGCGGTTACTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: fbaA
Ortholog function: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)
Lactococcus lactis subsp. cremoris SK11 LACR_2168 -100 4.4 AATAAAGCGGTTACTT
Lactococcus lactis subsp. lactis Il1403 L0009 -100 4.4 AATAAAGCGGTTACTT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0336 -107 4 GAGAAAACGCTTTAAG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1717 -19 4 GAGAAAACGCTTTAAG
Streptococcus mitis B6 smi_0695 -137 4.6 TAGAAAGGGTTTACAT
Streptococcus pyogenes M1 GAS SPy1889 -107 4.2 TGGAAAACGCTTTAAG
Streptococcus thermophilus CNRZ1066 str1899 -106 4.6 ATCAAAACGCTTACAA
-44 4.2 ATGTAAACGGGTTCAA
Position: -109
Score: 4.2
Sequence: TATGAAGCGATTTCAT
Locus tag: LACR_2247
LACR_2247 -109 4.2 TATGAAGCGATTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: fruR2
Ortholog function: Predicted fructose utilization transcriptional regulator FruR2, RpiR family
Lactococcus lactis subsp. cremoris SK11 LACR_2247 -109 4.2 TATGAAGCGATTTCAT
Position: -30
Score: 4.3
Sequence: AATAAAACGCATACAT
Locus tag: LACR_2294
LACR_2294 -30 4.3 AATAAAACGCATACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ackA
Ortholog function: Acetate kinase (EC 2.7.2.1)
Lactococcus lactis subsp. cremoris SK11 LACR_2294 -30 4.3 AATAAAACGCATACAT
Lactococcus lactis subsp. cremoris SK11 LACR_2295 -129 4.4 ATGCAAACGCTTTTTA
Lactococcus lactis subsp. lactis Il1403 L0224 -30 4.3 AATAAAACGCATACAT
Lactococcus lactis subsp. lactis Il1403 L73818 -129 4.5 TTGAAAAGGTTTTTAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0142 -28 4.9 TAGAAAACGATTTCAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0124 -28 4.6 CAGAAAACGATTTCAA
Streptococcus gallolyticus UCN34 GALLO_0095 -25 4.4 ATGAAAGCGCTTTAGA
Streptococcus gordonii str. Challis substr. CH1 SGO_1916 -26 4.6 CTGAAAACGCTTAAAA
Streptococcus mitis B6 smi_0214 -90 5 ATGAAAACGCTTAAAA
Streptococcus mutans UA159 SMU.1978 -28 4.3 TCGTAAACGATTTCAT
Streptococcus pneumoniae TIGR4 SP_2044 -30 4.9 TTGAAAACGCTTAAAA
Streptococcus pyogenes M1 GAS SPy0109 -28 4.6 CAGAAAACGATTTCAA
Streptococcus sanguinis SK36 SSA_0192 -26 4.6 TTGAAAACGCTTAAAG
3 4.3 TCGAAAACGATTTCTA
Streptococcus suis 05ZYH33 SSU05_0135 -27 4.5 AGGAAAACGCTTTAAA
Streptococcus thermophilus CNRZ1066 str1857 0 4.9 TTGAAAGCGTTTTATA
Streptococcus uberis 0140J SUB0126 -28 4.6 CAGAAAACGATTTCAA
Position: -129
Score: 4.4
Sequence: ATGCAAACGCTTTTTA
Locus tag: LACR_2295
LACR_2295 -129 4.4 ATGCAAACGCTTTTTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ackA
Ortholog function: Acetate kinase (EC 2.7.2.1)
Lactococcus lactis subsp. cremoris SK11 LACR_2294 -30 4.3 AATAAAACGCATACAT
Lactococcus lactis subsp. cremoris SK11 LACR_2295 -129 4.4 ATGCAAACGCTTTTTA
Lactococcus lactis subsp. lactis Il1403 L0224 -30 4.3 AATAAAACGCATACAT
Lactococcus lactis subsp. lactis Il1403 L73818 -129 4.5 TTGAAAAGGTTTTTAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0142 -28 4.9 TAGAAAACGATTTCAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0124 -28 4.6 CAGAAAACGATTTCAA
Streptococcus gallolyticus UCN34 GALLO_0095 -25 4.4 ATGAAAGCGCTTTAGA
Streptococcus gordonii str. Challis substr. CH1 SGO_1916 -26 4.6 CTGAAAACGCTTAAAA
Streptococcus mitis B6 smi_0214 -90 5 ATGAAAACGCTTAAAA
Streptococcus mutans UA159 SMU.1978 -28 4.3 TCGTAAACGATTTCAT
Streptococcus pneumoniae TIGR4 SP_2044 -30 4.9 TTGAAAACGCTTAAAA
Streptococcus pyogenes M1 GAS SPy0109 -28 4.6 CAGAAAACGATTTCAA
Streptococcus sanguinis SK36 SSA_0192 -26 4.6 TTGAAAACGCTTAAAG
3 4.3 TCGAAAACGATTTCTA
Streptococcus suis 05ZYH33 SSU05_0135 -27 4.5 AGGAAAACGCTTTAAA
Streptococcus thermophilus CNRZ1066 str1857 0 4.9 TTGAAAGCGTTTTATA
Streptococcus uberis 0140J SUB0126 -28 4.6 CAGAAAACGATTTCAA
Position: -71
Score: 4
Sequence: TTGTAAACGTGTGCAT
Locus tag: LACR_2298
LACR_2298 -71 4 TTGTAAACGTGTGCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: typA
Ortholog function: GTP-binding protein TypA/BipA
Lactococcus lactis subsp. cremoris SK11 LACR_2298 -167 3.8 TATTTAGCGATTTTAT
-71 4 TTGTAAACGTGTGCAT
Streptococcus agalactiae 2603V/R SAG0473 -96 4 ATGAAAACATTTACAC
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1513 -90 4.3 CTGAAAACATTTACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0589 -75 4.6 TTGAAAACATTTACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0669 -97 4 ATGAAAACATTTACAC
Streptococcus mutans UA159 SMU.546 -95 4.3 TTTAAAACATTTACAT
Streptococcus sanguinis SK36 SSA_0650 33 4 ATGAAAACATTTACAC
Streptococcus suis 05ZYH33 SSU05_0468 -89 4.3 CTGAAAACATTTACAA
Streptococcus thermophilus CNRZ1066 str0729 -89 4.3 TGAAAAACGTTTACAA
Streptococcus uberis 0140J SUB1296 -94 4.3 CTGAAAACATTTACAA
Position: -162
Score: 4.5
Sequence: ATGTAAACGATTTATA
Locus tag: LACR_2317
LACR_2317 -162 4.5 ATGTAAACGATTTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: aat
Ortholog function: Aspartate aminotransferase (EC 2.6.1.1)
Lactococcus lactis subsp. cremoris SK11 LACR_2317 -162 4.5 ATGTAAACGATTTATA
Lactococcus lactis subsp. lactis Il1403 L91456 -162 4.5 ATGTAAACGATTTATA
Streptococcus uberis 0140J SUB0687 -176 4.1 TTGAAAGCTATTTAAT
Position: -64
Score: 4.6
Sequence: CTGAAAACGCTTTTTT
Locus tag: LACR_2456
LACR_2456 -64 4.6 CTGAAAACGCTTTTTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ywcC
Ortholog function: 6-phosphogluconolactonase (EC 3.1.1.31)
Lactococcus lactis subsp. cremoris SK11 LACR_2456 -64 4.6 CTGAAAACGCTTTTTT
Lactococcus lactis subsp. lactis Il1403 L11851 -64 4.3 CTGAAACCGCTTTTTT
Streptococcus pneumoniae TIGR4 SP_1506 -85 4.4 TTTAAAGTGCTTACAT
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