Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of PerR regulog to Streptococcus pyogenes MGAS10750

Reference regulog properties
Source regulog: PerR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: FUR
Regulation mode: repressor
Biological process: Iron homeostasis; Manganese homeostasis; Oxidative stress response
Effector: Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pyogenes MGAS10750
Orthologous TF(s) MGAS10750_Spy0167
Regulated genes 5
Built upon 75 sites [see more]
Predicted regulatory interactions in Streptococcus pyogenes MGAS10750
Locus tag Position Score Sequence
Position: -36
Score: 5.6
Sequence: TAATAATCATTATAA
Locus tag: MGAS10750_Spy0369
MGAS10750_Spy0369 -36 5.6 TAATAATCATTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: mntR
Ortholog function: Manganese homeostasis transcriptional regulator MntR, DtxR family
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0487 -36 5.6 TAATAATGATTATAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1470 -36 5.6 TAATAATCATTATAA
Streptococcus pyogenes M1 GAS SPy0450 -36 5.6 TAATAATCATTATAA
Streptococcus uberis 0140J SUBp03 -37 5.6 TAATAATGATTATAA
Position: -121
Score: 5.6
Sequence: TTATAATGATTATTA
Locus tag: MGAS10750_Spy0370
MGAS10750_Spy0370 -121 5.6 TTATAATGATTATTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: mntA
Ortholog function: Manganese ABC transporter, substrate binding protein
Streptococcus agalactiae 2603V/R SAG1533 -28 5.1 TTATATTAATTTTAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0488 -124 5.6 TTATAATCATTATTA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1469 -124 5.6 TTATAATGATTATTA
Streptococcus gallolyticus UCN34 GALLO_2047 -66 4.8 TTATATTAAATATAA
Streptococcus mutans UA159 SMU.184 -26 4.8 TTATATTACTTATAA
Streptococcus pyogenes M1 GAS SPy0453 -124 5.6 TTATAATGATTATTA
Streptococcus sanguinis SK36 SSA_0260 -54 4.4 TTATATTAATTTTAG
Streptococcus uberis 0140J SUB0473 -123 5.6 TTATAATCATTATTA
Position: -64
Score: 5.8
Sequence: TTAGAATTATTATAA
Locus tag: MGAS10750_Spy1275
MGAS10750_Spy1275 -64 5.8 TTAGAATTATTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pmtA
Ortholog function: Predicted cation transporting ATPase
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1473 -98 5.5 TTAGAATCGTTCTAA
-65 5.8 TTAGAATTATTATAA
Streptococcus pyogenes M1 GAS SPy1434 -97 5.4 TTAGAATGTTTCTAA
-64 5.8 TTAGAATTATTATAA
Streptococcus suis 05ZYH33 SSU05_0309 -146 5.8 TTAGAATTATTATAA
-114 5.6 TTATAATCGTTATAA
-85 5.2 TGATAATAATTCTAA
Streptococcus uberis 0140J SUB1266 -98 5.8 TTAGAATTATTCTAA
-65 5.4 TTAGAATAGTTATAA
Position: -157
Score: 4.7
Sequence: CGATAATGATTCTAA
Locus tag: MGAS10750_Spy1367
MGAS10750_Spy1367 -157 4.7 CGATAATGATTCTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: mgrA
Ortholog function: Non-specific DNA-binding protein / Iron-binding ferritin-like antioxidant protein / Ferroxidase (EC 1.16.3.1)
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1517 -148 4.7 CGAGAATGATTCTAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0585 -136 4.7 CGAGAATGATTCTAA
Streptococcus gallolyticus UCN34 GALLO_0592 -76 5.8 TTAGAATTATTCTAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0665 -73 5.3 TTAGAAGCATTATAA
-37 5.9 TTAGAATGATTATAA
Streptococcus mutans UA159 SMU.540 -57 5.5 TTAGAATCGTTCTAA
Streptococcus pyogenes M1 GAS SPy1531 -157 4.7 CGATAATGATTCTAA
Streptococcus sanguinis SK36 SSA_0644 -71 5.3 TTAGAAGCATTATAA
-35 5.9 TTAGAATCATTATAA
Streptococcus suis 05ZYH33 SSU05_1689 -34 5.9 TTATAATTATTATAA
Streptococcus thermophilus CNRZ1066 str0723 -59 5.2 TTATAAATATTTTAA
Position: -154
Score: 5.7
Sequence: TTAGAATCATTTTAA
Locus tag: MGAS10750_Spy1860
MGAS10750_Spy1860 -154 5.7 TTAGAATCATTTTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ahpC
Ortholog function: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_2053 -159 5.7 TTAGAATGATTTTAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0137 -152 5.4 TTAGAATGGTTTTAA
Streptococcus pyogenes M1 GAS SPy2079 -154 5.7 TTAGAATCATTTTAA
Streptococcus uberis 0140J SUB1752 -142 5.8 TTAGAATTATTCTAA
© 2009-2020 RegPrecise