Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of NagR regulog to Streptococcus pyogenes MGAS10750

Reference regulog properties
Source regulog: NagR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: GntR/Others
Regulation mode: repressor
Biological process: N-acetylglucosamine utilization
Effector: N-acetylglucosamine-6-phosphate
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pyogenes MGAS10750
Orthologous TF(s) MGAS10750_Spy1066
Regulated genes 2
Built upon 66 sites [see more]
Predicted regulatory interactions in Streptococcus pyogenes MGAS10750
Locus tag Position Score Sequence
Position: -150
Score: 6.1
Sequence: TAATTAGACTATACCAATTT
Position: -72
Score: 5.7
Sequence: TAATATGACTATACCAATTA
Locus tag: MGAS10750_Spy1136
MGAS10750_Spy1136 -150 6.1 TAATTAGACTATACCAATTT
-72 5.7 TAATATGACTATACCAATTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: glmS
Ortholog function: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16)
Lactococcus lactis subsp. cremoris SK11 LACR_1094 -47 5 ATAATTAAATATACCAATTT
Lactococcus lactis subsp. lactis Il1403 L33556 -155 5.2 AAAATAAATTATACCAATTA
-47 5 ATAATTAACTATACCAATTT
Streptococcus agalactiae 2603V/R SAG0944 -153 5.4 CAAAAAGACTATACCAATTT
-75 5.2 ATATTAATATATACCAATTC
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1092 -146 5.4 CGATTAGACTATACCAATTT
-68 5.1 TCTAAGGACTATACCAATTA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0884 -148 5.7 AAATATGACTATACCAATTT
-69 5.3 ATATCTGACTATACCAATTA
Streptococcus gallolyticus UCN34 GALLO_0992 -157 5.1 TAATTGGTATATACAAAACT
-69 5.8 TTATTAGACTATACCAATTT
Streptococcus gordonii str. Challis substr. CH1 SGO_1757 -65 5.8 AAATCAGACTATACCAATTT
Streptococcus mitis B6 smi_1850 -136 5.8 AATTTGAACTATACCAATTT
-96 4.9 AAACAAGTATATACTGTTTT
-57 5.9 GAATTAGACTATACCAATTT
Streptococcus mutans UA159 SMU.1187 -148 5.4 CAAAAAGACTATACCAATTT
-71 5.8 TTATTAGACTATACCAATTA
Streptococcus pneumoniae TIGR4 SP_0266 -136 5.8 AATTTGAACTATACCAATTT
-96 4.9 AAACAAGTATATACTGTTTT
-57 5.9 GAATTAGACTATACCAATTT
Streptococcus pyogenes M1 GAS SPy1280 -150 6.1 TAATTAGACTATACCAATTT
-72 6.2 TAATTAGACTATACCAATTA
Streptococcus sanguinis SK36 SSA_2107 -147 5.3 AAAGAAAACTATACCAATTT
-69 5 CAAGTATACTATACCAATTT
Streptococcus suis 05ZYH33 SSU05_0549 -135 6 AAATTAGACTAGACCAATTA
-57 5.9 AAATTAGACTAGACCAATTT
Streptococcus thermophilus CNRZ1066 str0873 -107 4.4 TATATGGAATATACTGTCTT
-68 4.8 CTTATTGACTATACCAATTT
Streptococcus uberis 0140J SUB0998 -145 5.8 AAATTAGACTATACCAATAA
-67 5.5 TTATTTGACTATACCAATTT
Position: -68
Score: 6.3
Sequence: AAAGTGGTATATACCATTTA
Locus tag: MGAS10750_Spy1500
MGAS10750_Spy1500 -68 6.3 AAAGTGGTATATACCATTTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: nagA
Ortholog function: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
Lactococcus lactis subsp. cremoris SK11 LACR_1458 -74 5.6 TAATTGGTATATACTGTTTA
Lactococcus lactis subsp. lactis Il1403 L173068 -74 5.6 TAATTGGTATATACTGTTTA
Streptococcus agalactiae 2603V/R SAG0266 -67 6.4 AAATAGGTATATACCATTTA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1751 -67 6.2 TAAGTGGTATATACCATTTA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0477 -68 5.4 GGACTGGTATATACCATTTA
Streptococcus gallolyticus UCN34 GALLO_0390 -69 6.4 AATTTGGTATATACCATTTA
Streptococcus gordonii str. Challis substr. CH1 SGO_0549 -118 6.4 AAATAGGTCTATACCATTTA
Streptococcus mitis B6 smi_0202 -95 6.4 AAATAGGTCTATACCATTTA
Streptococcus mutans UA159 SMU.435 -43 6.4 AATTTGGTATATACCATTTA
Streptococcus pneumoniae TIGR4 SP_2056 -95 6.4 AAATAGGTCTATACCATTTA
Streptococcus pyogenes M1 GAS SPy1694 -68 6.3 AAAGTGGTATATACCATTTA
Streptococcus sanguinis SK36 SSA_1893 -174 6.4 AAATAGGTATATACCATTTA
Streptococcus uberis 0140J SUB1443 -67 6.2 AAACTGGTATATACCATTTA