Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of MalR regulog to Streptococcus pyogenes MGAS10270

Reference regulog properties
Source regulog: MalR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: LacI
Regulation mode: repressor
Biological process: Maltose utilization; Maltodextrin utilization
Effector: Maltose
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pyogenes MGAS10270
Orthologous TF(s) MGAS10270_Spy1113
Regulated genes 7
Built upon 80 sites [see more]
Predicted regulatory interactions in Streptococcus pyogenes MGAS10270
Locus tag Position Score Sequence
Position: -58
Score: 6
Sequence: TTACGCAAGCGCTTGCGTTA
Locus tag: MGAS10270_Spy1112
MGAS10270_Spy1112 -58 6 TTACGCAAGCGCTTGCGTTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: malM
Ortholog function: 4-alpha-glucanotransferase (amylomaltase) (EC 2.4.1.25)
Streptococcus agalactiae 2603V/R SAG1439 -61 5.8 TTATGCAATCGCTTGCGTTA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1293 -59 6.4 TTACGCAAACGGTTGCGTTA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1255 -84 6.1 TTGCGCAAACGGTTGCGTTA
Streptococcus gallolyticus UCN34 GALLO_1397 -60 6.1 TTACGCAAACGGTTGCGCTA
Streptococcus mutans UA159 SMU.1565 -61 6.4 TTATGCAAACGATTGCGTTA
Streptococcus pyogenes M1 GAS SPy1292 -58 6 TTACGCAAGCGCTTGCGTTA
Streptococcus suis 05ZYH33 SSU05_0392 -57 6.2 AAGTGCAAACGTTTGCGTTA
Streptococcus thermophilus CNRZ1066 str1013 -57 5.6 ACGTGCAACCGTTTGCATTA
Streptococcus uberis 0140J SUB1141 -56 6.4 TTACGCAAACGGTTGCGTTA
Position: -129
Score: 5.8
Sequence: TTATGCAACCGCTTGCAGAA
Locus tag: MGAS10270_Spy1113
MGAS10270_Spy1113 -129 5.8 TTATGCAACCGCTTGCAGAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: malR
Ortholog function: Maltose utilization transcriptional regulator MalR, LacI family
Streptococcus agalactiae 2603V/R SAG1440 -215 6 TTATGCAACCGTTTGCAAAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1256 -210 5.8 TTATGCAACCGCTTGCAGAA
Streptococcus gallolyticus UCN34 GALLO_1398 -270 5.6 TTATGCAACCGTTTGCAGGA
-123 5.2 AAAAGCAAACAATTGCAGAA
Streptococcus mutans UA159 SMU.1566 -200 5.8 TTATGCAATCGTTTGCGAAA
Streptococcus pyogenes M1 GAS SPy1293 -207 5.8 TTATGCAACCGCTTGCAGAA
Streptococcus thermophilus CNRZ1066 str1014 -109 5.3 TTATGAAACCGTTATCATAA
Streptococcus uberis 0140J SUB1142 -161 6 TTATGCAACCGTTTGCAGAA
Position: -58
Score: 6
Sequence: TTCTGCAAGCGGTTGCATAA
Locus tag: MGAS10270_Spy1114
MGAS10270_Spy1114 -58 6 TTCTGCAAGCGGTTGCATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: malE
Ortholog function: Maltose/maltodextrin ABC transporter, substrate-binding protein
Lactococcus lactis subsp. cremoris SK11 LACR_1853 -68 6.1 AAAAGCAAACGGTTGCGTAA
Lactococcus lactis subsp. lactis Il1403 L128695 -68 5.6 AAAAGCAAACGGTTGTGTAA
Streptococcus agalactiae 2603V/R SAG1441 -60 6.1 TTTTGCAAACGGTTGCATAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1296 -58 6 TTCTGCAAGCGGTTGCATAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1257 -58 6 TTCTGCAAGCGGTTGCATAA
Streptococcus gallolyticus UCN34 GALLO_1399 -68 5.9 TCCTGCAAACGGTTGCATAA
Streptococcus mutans UA159 SMU.1568 -66 6 TTTCGCAAACGATTGCATAA
Streptococcus pyogenes M1 GAS SPy1294 -58 6 TTCTGCAAGCGGTTGCATAA
Streptococcus sanguinis SK36 SSA_1298 -56 6 AATTGCAAACGGTTGCATAA
Streptococcus uberis 0140J SUB1143 -55 6.2 TTCTGCAAACGGTTGCATAA
Position: -39
Score: 5.2
Sequence: TCTTGCAAGCGCTTGCGCAA
Locus tag: MGAS10270_Spy1749
MGAS10270_Spy1749 -39 5.2 TCTTGCAAGCGCTTGCGCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pulA
Ortholog function: Pullulanase (EC 3.2.1.41)
Streptococcus agalactiae 2603V/R SAG1216 -67 5.5 TGTTGCAAGCGCTTGCGTAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0237 -67 6 TATTGCAAGCGTTTGCGTAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0820 -77 5.2 CAAAGAAAACGATTGCACTA
Streptococcus gallolyticus UCN34 GALLO_1462 -85 6 TTACGAAAACGCTTGCGTAA
Streptococcus mitis B6 smi_1848 -72 4.9 TCGAGAAAACGCTTGCATAT
Streptococcus pneumoniae TIGR4 SP_0268 -72 5.2 CAAAGAAAACGCTTGCATAT
Streptococcus pyogenes M1 GAS SPy1972 -66 5.2 TCTTGCAAGCGCTTGCGCAA
Streptococcus sanguinis SK36 SSA_0453 -58 5.2 TACAGAAAACGTTTGCATAG
Position: -54
Score: 6.1
Sequence: TTGCGCAAACGATTGCATAA
Locus tag: MGAS10270_Spy1750
MGAS10270_Spy1750 -54 6.1 TTGCGCAAACGATTGCATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: dexB
Ortholog function: Glucan 1,6-alpha-glucosidase (EC 3.2.1.70)
Streptococcus agalactiae 2603V/R SAG1924 -75 5.9 TTACGCAAACGCTTGCACTA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1771 -126 5.8 AAATGCAAGCGATTGCGCTA
Streptococcus gallolyticus UCN34 GALLO_0196 -72 6 TAACGCAAACGCTTGCGCAA
Streptococcus mitis B6 smi_1761 -75 6.1 TTAGGCAAACGCTTGCATAA
Streptococcus pneumoniae TIGR4 SP_0342 -75 5.8 TTAAGCAAACGCTTGCACAA
Streptococcus pyogenes M1 GAS SPy1973 -75 5.8 TTGCGCAAACGATTGCACAA
Position: -103
Score: 5.6
Sequence: CAATGCAAGCGATTGCATCA
Locus tag: MGAS10270_Spy1759
MGAS10270_Spy1759 -103 5.6 CAATGCAAGCGATTGCATCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ptsG
Ortholog function: PTS system glucose-specific EIICBA component (EC 2.7.1.69)
Streptococcus agalactiae 2603V/R SAG1959 -45 5.9 TAACGCAAACGCTTGCACTA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0222 -103 6.5 TAACGCAAACGTTTGCGTAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1783 -108 6.1 AAGCGCAAACGTTTGCGTTA
Streptococcus gallolyticus UCN34 GALLO_0149 -132 6.3 CAACGCAAACGTTTGCGTAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0505 -290 5.3 TCACGCAATCGTTTGCTTAA
-49 5.6 CAATGCAAACGATTTCATAT
Streptococcus mitis B6 smi_1404 -54 5.9 AAGTGCAAACGTTTTCGTAA
Streptococcus mutans UA159 SMU.2047 -45 6.1 AAATGCAAACGTTTGCATGA
Streptococcus pneumoniae TIGR4 SP_0758 -54 5.9 AAGTGCAAACGTTTTCGTAA
Streptococcus pyogenes M1 GAS SPy1986 -103 5.6 CAATGCAAGCGATTGCATCA
Streptococcus sanguinis SK36 SSA_1809 -195 5 TCATGCAATCGTTTTCGTTG
-56 5.5 ACATGCAAACGATTTCACAA
Streptococcus suis 05ZYH33 SSU05_0397 -72 5.8 TAATGCAAACGTTTACGCTA
-40 4.8 AAAAGAAAACGGTTACGCAT
Streptococcus suis 05ZYH33 SSU05_0398 -72 5.8 TAATGCAAACGTTTACGCTA
-40 4.8 AAAAGAAAACGGTTACGCAT
Streptococcus uberis 0140J SUB0236 -70 6.4 AAACGCAAACGTTTGCGTAA
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