Propagation of CodY regulog to Streptococcus suis 05ZYH33
| Source regulog: | CodY - Streptococcaceae |
| Regulator type: | Transcription factor |
| Regulator family: | CodY |
| Regulation mode: | repressor (activator) |
| Biological process: | Amino acid metabolism |
| Effector: | Guanosine triphosphate; Branched-chain amino acids |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Streptococcus suis 05ZYH33 |
| Orthologous TF(s) | SSU05_0350 |
| Regulated genes | 16 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -305
Score: 4.5 Sequence: ATTTTTTTGAGAATT
Position: -276
Score: 4.6 Sequence: AAGATTCTAAAAATT
Locus tag: SSU05_0121
|
||||
| SSU05_0121 | -305 | 4.5 | ATTTTTTTGAGAATT | |
| -276 | 4.6 | AAGATTCTAAAAATT | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: rpoB | ||||
| Ortholog function: DNA-directed RNA polymerase beta subunit (EC 2.7.7.6) | ||||
| Streptococcus agalactiae 2603V/R | SAG0160 | -128 | 5.2 | AACTTTCTGAAAATT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0131 | -91 | 4.6 | AAGATTCTAAAAATT |
| Streptococcus gallolyticus UCN34 | GALLO_0084 | -165 | 4.6 | AAGATTCTAAAAATT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1927 | -222 | 5.4 | ATTTTTCTGAAAATT |
| Streptococcus mitis B6 | smi_1847 | -113 | 5 | AAGATTCTGAAAATT |
| Streptococcus mutans UA159 | SMU.1990 | -84 | 5.3 | AAAATTCTGAAAATT |
| Streptococcus pneumoniae TIGR4 | SP_1961 | -112 | 5 | AAGATTCTGAAAATT |
| Streptococcus pyogenes M1 GAS | SPy0098 | -91 | 5.2 | AATATTCTAAAAATT |
| Streptococcus suis 05ZYH33 | SSU05_0121 | -276 | 4.6 | AAGATTCTAAAAATT |
| Streptococcus thermophilus CNRZ1066 | str1868 | -171 | 4.6 | AAAGTTCTAAAAATT |
| Streptococcus uberis 0140J | SUB0115 | -90 | 4.6 | AAGATTCTAAAAATT |
|
Position: -62
Score: 4.9 Sequence: AATTATCAGATAAAT
Position: -45
Score: 5.1 Sequence: AATTGTCAGACAATT
Locus tag: SSU05_0252
|
||||
| SSU05_0252 | -62 | 4.9 | AATTATCAGATAAAT | |
| -45 | 5.1 | AATTGTCAGACAATT | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: gdhA | ||||
| Ortholog function: NADP-specific glutamate dehydrogenase (EC 1.4.1.4) | ||||
| Streptococcus agalactiae 2603V/R | SAG1335 | -55 | 4.9 | AAAATTCTGACAATT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0823 | -61 | 5.3 | AAAATTCAGAAAATT |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_1090 | -65 | 5.3 | AAAATTCAGAAAATT |
| Streptococcus gallolyticus UCN34 | GALLO_1293 | -78 | 5.8 | AATTTTCAGAAAATT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0276 | -95 | 5.8 | AATTTTCAGAAAATT |
| Streptococcus mitis B6 | smi_0814 | -95 | 5.5 | AATTTTTAGAAAATT |
| Streptococcus mutans UA159 | SMU.913 | -68 | 5.6 | AATATTCAGAAAATT |
| Streptococcus pneumoniae TIGR4 | SP_1306 | -94 | 5.5 | AATTTTTAGAAAATT |
| Streptococcus sanguinis SK36 | SSA_0371 | -182 | 5.5 | AATTTTTAGAAAATT |
| Streptococcus suis 05ZYH33 | SSU05_0252 | -45 | 5.1 | AATTGTCAGACAATT |
| Streptococcus thermophilus CNRZ1066 | str0430 | -52 | 5 | AAGATTCTGAAAATT |
| Streptococcus uberis 0140J | SUB0762 | -60 | 5.6 | AATATTCTGAAAATT |
|
Position: -173
Score: 5.1 Sequence: ATTTTTTTGAAAATT
Locus tag: SSU05_0279
|
||||
| SSU05_0279 | -173 | 5.1 | ATTTTTTTGAAAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: adhB1 | ||||
| Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1) | ||||
| Streptococcus agalactiae 2603V/R | SAG0054 | -100 | 5.2 | AATTTTCTGAAAATC |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0062 | -113 | 5.2 | AATTTTCAGAAAACT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0565 | -282 | 5.4 | AATTGTCTGAAAATT |
| Streptococcus suis 05ZYH33 | SSU05_0279 | -173 | 5.1 | ATTTTTTTGAAAATT |
|
Position: -56
Score: 4.8 Sequence: AATTTTCTGTCAATT
Locus tag: SSU05_0281
|
||||
| SSU05_0281 | -56 | 4.8 | AATTTTCTGTCAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: thrC | ||||
| Ortholog function: Threonine synthase (EC 4.2.3.1) | ||||
| Streptococcus agalactiae 2603V/R | SAG0055 | -100 | 5.2 | AATTTTCTGAAAATC |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0063 | -113 | 5.2 | AATTTTCAGAAAACT |
| Streptococcus gallolyticus UCN34 | GALLO_0042 | -61 | 5.6 | AATTTTCTGATAATT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0139 | -57 | 5.2 | AATTTTCTGATAAAT |
| Streptococcus mitis B6 | smi_0193 | -57 | 5.4 | AATTTTCTGAAAAAT |
| Streptococcus mutans UA159 | SMU.70 | -59 | 5.2 | AATTGTCTGATAATT |
| Streptococcus pneumoniae TIGR4 | SP_2066 | -57 | 5.4 | AATTTTCTGAAAAAT |
| Streptococcus sanguinis SK36 | SSA_0095 | -57 | 5.2 | AATTTTCTGATAAAT |
| Streptococcus suis 05ZYH33 | SSU05_0281 | -56 | 4.8 | AATTTTCTGTCAATT |
| Streptococcus thermophilus CNRZ1066 | str1878 | -59 | 5.4 | AATTTTCTGACAATT |
|
Position: -74
Score: 5.3 Sequence: AATATTCTGATAATT
Locus tag: SSU05_0350
|
||||
| SSU05_0350 | -74 | 5.3 | AATATTCTGATAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: codY | ||||
| Ortholog function: Nutrient limitation global transcriptional regulator CodY, CodY family | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_0168 | -101 | 5.4 | AATTTTCTGACAATT |
| Lactococcus lactis subsp. lactis Il1403 | L0243 | -101 | 5.4 | AATTTTCTGACAATT |
| Streptococcus agalactiae 2603V/R | SAG1675 | -46 | 5 | AATTTTGAGAATATT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1848 | -80 | 5.6 | AATTTTCTGATAATT |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0387 | -78 | 5.6 | AATTTTCTGATAATT |
| Streptococcus gallolyticus UCN34 | GALLO_1876 | -77 | 5.6 | AATTTTCAGATAATT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0431 | -71 | 5.6 | AATTTTCAGATAATT |
| Streptococcus mitis B6 | smi_0687 | -71 | 5.6 | AATTTTCAGATAATT |
| Streptococcus mutans UA159 | SMU.1824c | -75 | 5.4 | AATTTTCTGACAATT |
| Streptococcus pneumoniae TIGR4 | SP_1584 | -71 | 5.6 | AATTTTCAGATAATT |
| Streptococcus pyogenes M1 GAS | SPy1777 | -80 | 5.6 | AATTTTCTGATAATT |
| Streptococcus sanguinis SK36 | SSA_0566 | -71 | 5.6 | AATTTTCAGATAATT |
| Streptococcus suis 05ZYH33 | SSU05_0350 | -74 | 5.3 | AATATTCTGATAATT |
| Streptococcus thermophilus CNRZ1066 | str1635 | -132 | 5.4 | AATTTTCAGACAATT |
| Streptococcus uberis 0140J | SUB1528 | -82 | 5.6 | AATTTTCTGATAATT |
|
Position: -63
Score: 4.6 Sequence: AAAAATCAGAAAATA
Locus tag: SSU05_0596
|
||||
| SSU05_0596 | -63 | 4.6 | AAAAATCAGAAAATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: aroA | ||||
| Ortholog function: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) | ||||
| Streptococcus gallolyticus UCN34 | GALLO_1433 | -56 | 4.6 | AATTTTCAGTTATTT |
| Streptococcus mutans UA159 | SMU.784 | -61 | 5.2 | AATTTTCTAAAATTT |
| Streptococcus suis 05ZYH33 | SSU05_0596 | -63 | 4.6 | AAAAATCAGAAAATA |
| Streptococcus suis 05ZYH33 | SSU05_0597 | -63 | 4.6 | AAAAATCAGAAAATA |
| Streptococcus suis 05ZYH33 | SSU05_0598 | -63 | 4.6 | AAAAATCAGAAAATA |
| Streptococcus thermophilus CNRZ1066 | str0645 | -81 | 4.9 | AATATTTTGACAATT |
|
Position: -54
Score: 5.2 Sequence: AATTGTCTGAATATT
Locus tag: SSU05_0665
|
||||
| SSU05_0665 | -54 | 5.2 | AATTGTCTGAATATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: serC | ||||
| Ortholog function: Phosphoserine aminotransferase (EC 2.6.1.52) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_0619 | -59 | 5.6 | AATTATCAGAAAATT |
| Lactococcus lactis subsp. lactis Il1403 | L0083 | -59 | 5.6 | AATTATCAGAAAATT |
| Streptococcus gallolyticus UCN34 | GALLO_1746 | -51 | 5.3 | AAAATTCAGAAAATT |
| Streptococcus mutans UA159 | SMU.1656 | -50 | 5.3 | AAAATTCTGAAAATT |
| Streptococcus suis 05ZYH33 | SSU05_0665 | -54 | 5.2 | AATTGTCTGAATATT |
| Streptococcus uberis 0140J | SUB0445 | -53 | 5.3 | AAAATTCTGAAAATT |
|
Position: -52
Score: 5 Sequence: AATAGTCAGAATATT
Locus tag: SSU05_0801
|
||||
| SSU05_0801 | -52 | 5 | AATAGTCAGAATATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: hom | ||||
| Ortholog function: Homoserine dehydrogenase (EC 1.1.1.3) | ||||
| Lactococcus lactis subsp. lactis Il1403 | L0090 | -41 | 4.9 | AATTATCTTAAAATT |
| Streptococcus gallolyticus UCN34 | GALLO_1241 | -118 | 4.8 | ATTTTTCTGTAAATT |
| Streptococcus mitis B6 | smi_0773 | -56 | 5.2 | AATTTTCACAAAATT |
| Streptococcus pneumoniae TIGR4 | SP_1361 | -56 | 5.2 | AATTTTCACAAAATT |
| Streptococcus suis 05ZYH33 | SSU05_0801 | -52 | 5 | AATAGTCAGAATATT |
| Streptococcus thermophilus CNRZ1066 | str0469 | -70 | 4.6 | AATATTCTGTCAATT |
|
Position: -146
Score: 5.1 Sequence: AATTTTCAGAATATA
Locus tag: SSU05_0811
|
||||
| SSU05_0811 | -146 | 5.1 | AATTTTCAGAATATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: scpC | ||||
| Ortholog function: Serine endopeptidase ScpC (EC 3.4.21.-) | ||||
| Streptococcus suis 05ZYH33 | SSU05_0811 | -146 | 5.1 | AATTTTCAGAATATA |
|
Position: -73
Score: 5.3 Sequence: TATTTTCAGAAAATT
Locus tag: SSU05_1547
|
||||
| SSU05_1547 | -73 | 5.3 | TATTTTCAGAAAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: livH | ||||
| Ortholog function: Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1) | ||||
| Streptococcus agalactiae 2603V/R | SAG1581 | -56 | 5.3 | AATATTCTGATAATT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0444 | -98 | 4.9 | ATTTTTCAAAATATT |
| -65 | 5.6 | AATTTTCTGATAATT | ||
| Streptococcus gallolyticus UCN34 | GALLO_1759 | -66 | 5.6 | AATTTTCTGATAATT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1629 | -66 | 5.6 | AATTTTCTGATAATT |
| Streptococcus mitis B6 | smi_1414 | -61 | 5.6 | AATTTTCTGATAATT |
| Streptococcus mutans UA159 | SMU.1668 | -66 | 5.3 | AATATTCAGATAATT |
| Streptococcus pneumoniae TIGR4 | SP_0750 | -60 | 5.6 | AATTTTCTGATAATT |
| Streptococcus sanguinis SK36 | SSA_1728 | -65 | 5.2 | AATTGTCAGATAATT |
| Streptococcus suis 05ZYH33 | SSU05_1547 | -117 | 4.9 | AATTTTCTGTAATTT |
| -73 | 5.3 | TATTTTCAGAAAATT | ||
| Streptococcus thermophilus CNRZ1066 | str0360 | -65 | 5.6 | AATTTTCTGATAATT |
| Streptococcus uberis 0140J | SUB0433 | -66 | 5.6 | AATTTTCTGATAATT |
|
Position: -64
Score: 5.6 Sequence: AATTTTCAGATAATT
Locus tag: SSU05_1548
|
||||
| SSU05_1548 | -64 | 5.6 | AATTTTCAGATAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: livK | ||||
| Ortholog function: Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1) | ||||
| Streptococcus agalactiae 2603V/R | SAG1582 | -56 | 5.3 | AATATTCTGATAATT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0443 | -98 | 4.9 | ATTTTTCAAAATATT |
| -65 | 5.6 | AATTTTCTGATAATT | ||
| Streptococcus gallolyticus UCN34 | GALLO_1760 | -66 | 5.6 | AATTTTCTGATAATT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1630 | -66 | 5.6 | AATTTTCTGATAATT |
| Streptococcus mitis B6 | smi_1415 | -61 | 5.6 | AATTTTCTGATAATT |
| Streptococcus mutans UA159 | SMU.1669 | -66 | 5.3 | AATATTCAGATAATT |
| Streptococcus pneumoniae TIGR4 | SP_0749 | -60 | 5.6 | AATTTTCTGATAATT |
| Streptococcus sanguinis SK36 | SSA_1729 | -65 | 5.2 | AATTGTCAGATAATT |
| Streptococcus suis 05ZYH33 | SSU05_1548 | -64 | 5.6 | AATTTTCAGATAATT |
| Streptococcus thermophilus CNRZ1066 | str0359 | -65 | 5.6 | AATTTTCTGATAATT |
| Streptococcus uberis 0140J | SUB0432 | -66 | 5.6 | AATTTTCTGATAATT |
|
Position: -123
Score: 4.6 Sequence: GTTTTTCTGAAATTT
Locus tag: SSU05_1811
|
||||
| SSU05_1811 | -123 | 4.6 | GTTTTTCTGAAATTT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: thrA | ||||
| Ortholog function: Aspartokinase (EC 2.7.2.4) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_0783 | -71 | 5.6 | AATTATCTGAAAATT |
| Lactococcus lactis subsp. lactis Il1403 | L0097 | -70 | 5.6 | AATTATCTGAAAATT |
| Streptococcus agalactiae 2603V/R | SAG0339 | -52 | 4.9 | AATTTTCTGACTTTT |
| Streptococcus gallolyticus UCN34 | GALLO_0331 | -52 | 5.3 | AATTTTCAGAATTTT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1701 | -38 | 4.5 | AATTGTTTGAATAAT |
| Streptococcus mutans UA159 | SMU.1748 | -53 | 5.3 | AATTTTCTGAATTTT |
| Streptococcus sanguinis SK36 | SSA_1943 | -47 | 5.3 | AATTTTCAGAATTTT |
| Streptococcus suis 05ZYH33 | SSU05_1811 | -123 | 4.6 | GTTTTTCTGAAATTT |
| Streptococcus thermophilus CNRZ1066 | str0378 | -56 | 5.1 | AATTATCAGAATTTT |
| Streptococcus uberis 0140J | SUB0316 | -26 | 5 | AATATTCATAAAATT |
|
Position: -306
Score: 5.4 Sequence: ATTTTTCAGAAAATT
Locus tag: SSU05_1949
|
||||
| SSU05_1949 | -306 | 5.4 | ATTTTTCAGAAAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: leuA | ||||
| Ortholog function: 2-isopropylmalate synthase (EC 2.3.3.13) | ||||
| Streptococcus gallolyticus UCN34 | GALLO_0758 | -266 | 5 | AGTATTCAGAAAATT |
| Streptococcus mitis B6 | smi_1218 | -259 | 5.3 | AATTTTCAGAAAATA |
| Streptococcus mutans UA159 | SMU.1384 | -246 | 5.4 | ATTTTTCAGAAAATT |
| Streptococcus sanguinis SK36 | SSA_0975 | -269 | 5.3 | AATTTTCAGAAAATA |