Propagation of CodY regulog to Streptococcus pyogenes MGAS10394

Reference regulog properties
Source regulog:	CodY - Streptococcaceae
Regulator type:	Transcription factor
Regulator family:	CodY
Regulation mode:	repressor (activator)
Biological process:	Amino acid metabolism
Effector:	Guanosine triphosphate; Branched-chain amino acids
Phylum:	Firmicutes
Propagated regulon:
Target genome	Streptococcus pyogenes MGAS10394
Orthologous TF(s)	M6_Spy1505
Regulated genes	9

Built upon 273 sites [see more]

Predicted regulatory interactions in *Streptococcus pyogenes MGAS10394*
	Locus tag	Position	Score	Sequence
Position: -91 Score: 5.2 Sequence: AATATTCTAAAAATT Locus tag: M6_Spy0131
	M6_Spy0131	-91	5.2	AATATTCTAAAAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: rpoB
Ortholog function: DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)
Streptococcus agalactiae 2603V/R	SAG0160	-128	5.2	AACTTTCTGAAAATT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0131	-91	4.6	AAGATTCTAAAAATT
Streptococcus gallolyticus UCN34	GALLO_0084	-165	4.6	AAGATTCTAAAAATT
Streptococcus gordonii str. Challis substr. CH1	SGO_1927	-222	5.4	ATTTTTCTGAAAATT
Streptococcus mitis B6	smi_1847	-113	5	AAGATTCTGAAAATT
Streptococcus mutans UA159	SMU.1990	-84	5.3	AAAATTCTGAAAATT
Streptococcus pneumoniae TIGR4	SP_1961	-112	5	AAGATTCTGAAAATT
Streptococcus pyogenes M1 GAS	SPy0098	-91	5.2	AATATTCTAAAAATT
Streptococcus suis 05ZYH33	SSU05_0121	-276	4.6	AAGATTCTAAAAATT
Streptococcus thermophilus CNRZ1066	str1868	-171	4.6	AAAGTTCTAAAAATT
Streptococcus uberis 0140J	SUB0115	-90	4.6	AAGATTCTAAAAATT

Position: -126 Score: 5.3 Sequence: AATATTCAGATAATT Locus tag: M6_Spy0280
	M6_Spy0280	-126	5.3	AATATTCAGATAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: oppA2
Ortholog function: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0356	-115	5.3	AATATTCAGATAATT
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1697	-119	5.3	AATATTCAGATAATT

Position: -131 Score: 4.8 Sequence: AATTTTCAGTCAATT Locus tag: M6_Spy0302
	M6_Spy0302	-131	4.8	AATTTTCAGTCAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: braB
Ortholog function: Branched-chain amino acid transport system carrier protein
Streptococcus pyogenes M1 GAS	SPy0323	-131	4.8	AATTTTCAGTCAATT
Streptococcus uberis 0140J	SUB0370	-43	5.1	AATTGTTAGAAAATT

Position: -96 Score: 4.5 Sequence: AATTATCAGAGTTTT Position: -87 Score: 4.6 Sequence: AGTTTTCAGATATTT Locus tag: M6_Spy1093
	M6_Spy1093	-96	4.5	AATTATCAGAGTTTT
		-87	4.6	AGTTTTCAGATATTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: gapN
Ortholog function: Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)
Streptococcus agalactiae 2603V/R	SAG0823	-72	4.6	ATATGTCAGATAATT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1419	-87	4.9	AATTTTCTGATACTT
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0766	-87	4.6	AATTTTCAGACTCTT
Streptococcus gallolyticus UCN34	GALLO_0746	-87	5.3	AATTTTCTGAATTTT
Streptococcus mutans UA159	SMU.676	-89	5.3	AATTTTCTGAATTTT
Streptococcus pneumoniae TIGR4	SP_1119	-55	5.2	GATTTTCTGAAAATT
Streptococcus pyogenes M1 GAS	SPy1371	-87	5.3	AATTTTCAGATATTT
Streptococcus sanguinis SK36	SSA_0774	-53	5.8	AATTTTCAGAAAATT
Streptococcus thermophilus CNRZ1066	str1263	-89	5	AATTTTCTGAATACT
Streptococcus uberis 0140J	SUB1220	-87	5.4	AATTTTCAGACAATT

Position: -29 Score: 5.1 Sequence: AATTTTTAAAAAATT Locus tag: M6_Spy1179
	M6_Spy1179	-29	5.1	AATTTTTAAAAAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kup
Ortholog function: Kup system potassium uptake protein
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1454	-93	4.8	AATTTTCTGAAAAAG
		-29	5.1	AATTTTTAAAAAATT
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0647	-89	5.3	AATTTTCTGAAAATA
Streptococcus pyogenes M1 GAS	SPy1414	-93	4.8	AATTTTCTGAAAAAG
		-29	5.1	AATTTTTAAAAAATT

Position: -107 Score: 4.9 Sequence: ATTTTTCAAAATATT Locus tag: M6_Spy1290
	M6_Spy1290	-107	4.9	ATTTTTCAAAATATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: asnA
Ortholog function: Aspartate--ammonia ligase (EC 6.3.1.1)
Streptococcus gallolyticus UCN34	GALLO_0534	-144	4.8	AATTTTCAAAAAAGT
Streptococcus pyogenes M1 GAS	SPy1539	-107	4.9	ATTTTTCAAAATATT
Streptococcus suis 05ZYH33	SSU05_0467	-124	5.3	AATTATCAGAATATT
Streptococcus uberis 0140J	SUB1323	-123	4.6	AATATACTGAAAAAT

Position: -41 Score: 5 Sequence: AATTTTCTGAAAAAA Locus tag: M6_Spy1405
	M6_Spy1405	-41	5	AATTTTCTGAAAAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: aapA
Ortholog function: Amino acid permease
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1715	-41	5	AATTTTCTGAAAAAA
Streptococcus pyogenes M1 GAS	SPy1654	-53	5	AATTTTCTGAAAAAA
Streptococcus thermophilus CNRZ1066	str0509	-108	4.7	AATATTCTGAATTAT
Streptococcus uberis 0140J	SUB1411	-54	4.8	AATATTCTGAAAAAA

Position: -17 Score: 5.6 Sequence: AATTTTCTGATAATT Locus tag: M6_Spy1505
	M6_Spy1505	-17	5.6	AATTTTCTGATAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: codY
Ortholog function: Nutrient limitation global transcriptional regulator CodY, CodY family
Lactococcus lactis subsp. cremoris SK11	LACR_0168	-101	5.4	AATTTTCTGACAATT
Lactococcus lactis subsp. lactis Il1403	L0243	-101	5.4	AATTTTCTGACAATT
Streptococcus agalactiae 2603V/R	SAG1675	-46	5	AATTTTGAGAATATT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1848	-80	5.6	AATTTTCTGATAATT
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0387	-78	5.6	AATTTTCTGATAATT
Streptococcus gallolyticus UCN34	GALLO_1876	-77	5.6	AATTTTCAGATAATT
Streptococcus gordonii str. Challis substr. CH1	SGO_0431	-71	5.6	AATTTTCAGATAATT
Streptococcus mitis B6	smi_0687	-71	5.6	AATTTTCAGATAATT
Streptococcus mutans UA159	SMU.1824c	-75	5.4	AATTTTCTGACAATT
Streptococcus pneumoniae TIGR4	SP_1584	-71	5.6	AATTTTCAGATAATT
Streptococcus pyogenes M1 GAS	SPy1777	-80	5.6	AATTTTCTGATAATT
Streptococcus sanguinis SK36	SSA_0566	-71	5.6	AATTTTCAGATAATT
Streptococcus suis 05ZYH33	SSU05_0350	-74	5.3	AATATTCTGATAATT
Streptococcus thermophilus CNRZ1066	str1635	-132	5.4	AATTTTCAGACAATT
Streptococcus uberis 0140J	SUB1528	-82	5.6	AATTTTCTGATAATT

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of CodY regulog to Streptococcus pyogenes MGAS10394

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --