Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of AdcR regulog to Streptococcus pyogenes MGAS10394

Reference regulog properties
Source regulog: AdcR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: MarR
Regulation mode: repressor
Biological process: Zinc homeostasis
Effector: Zinc ion, (Zn2+)
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pyogenes MGAS10394
Orthologous TF(s) M6_Spy0125
Regulated genes 7
Built upon 72 sites [see more]
Predicted regulatory interactions in Streptococcus pyogenes MGAS10394
Locus tag Position Score Sequence
Position: -116
Score: 5.2
Sequence: GATTAACCAGTTAAGT
Locus tag: M6_Spy0090
M6_Spy0090 -116 5.2 GATTAACCAGTTAAGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhB1
Ortholog function: Alcohol dehydrogenase, zinc dependent (EC 1.1.1.1)
Streptococcus agalactiae 2603V/R SAG0054 -128 5.2 GATTAACCGGTTAAGA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0062 -130 5.6 ACTTAACTAGTTAACT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0046 -135 5.6 ACTTAACTGGTTAAGT
Streptococcus pyogenes M1 GAS SPy0044 -116 5.2 GATTAACCAGTTAAGT
Position: -29
Score: 5.7
Sequence: AATTAACTGGTTAATG
Locus tag: M6_Spy0125
M6_Spy0125 -29 5.7 AATTAACTGGTTAATG
Supported by regulated orthologs from reference regulons
Ortholog gene name: adcR
Ortholog function: Zinc homeostasis trancsriptional regulator AdcR, MarR family
Streptococcus agalactiae 2603V/R SAG0154 -30 5.5 AATTTACTGGTTAACA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0126 -29 5.7 AATTAACTGGTTAATG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0103 -30 5.7 AATTAACTGGTTAATG
Streptococcus gallolyticus UCN34 GALLO_0079 -32 5.7 AATTAACTGGTTAATG
Streptococcus mutans UA159 SMU.1995c -32 5.9 AATTAACTGGTTAATT
Streptococcus pneumoniae TIGR4 SP_2172 -78 5.9 AATTAACTGGTAAACA
Streptococcus pyogenes M1 GAS SPy0092 -29 5.7 AATTAACTGGTTAATG
Streptococcus sanguinis SK36 SSA_0135 -45 5.6 AATTAACCAGTAAAGC
Streptococcus suis 05ZYH33 SSU05_0109 -30 5.4 ACTTAACAAGTTAATT
Streptococcus uberis 0140J SUB0110 -30 5.9 AATTAACTGGTTAAGA
Position: -45
Score: 5.7
Sequence: ACTTAACTGGTAAATT
Locus tag: M6_Spy0563
M6_Spy0563 -45 5.7 ACTTAACTGGTAAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: adcA
Ortholog function: Zinc ABC transporter, substrate-binding protein
Streptococcus agalactiae 2603V/R SAG0535 -41 5.5 TATTAACCGGTAAATA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0674 -45 5.2 ACTTAACTGGTCAATT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0736 -55 5.6 ACTTAACCAGTAAATA
Streptococcus gallolyticus UCN34 GALLO_0737 -43 5.6 ACTTAACCAGTAAACT
Streptococcus gordonii str. Challis substr. CH1 SGO_1936 -35 5.2 CATTAACTGGTTAAGT
Streptococcus mitis B6 smi_2024 -77 5.9 AATTAACCAGTAAATA
Streptococcus mutans UA159 SMU.1302 -29 5.8 AATTAACCAGTTAAGT
Streptococcus pneumoniae TIGR4 SP_2169 -78 5.9 AATTAACTGGTAAACA
Streptococcus pyogenes M1 GAS SPy0714 -45 5.2 ACTTAACTGGTCAATT
Streptococcus sanguinis SK36 SSA_0138 -45 5.6 AATTAACCAGTAAAGC
Streptococcus suis 05ZYH33 SSU05_0112 -30 5.4 ACTTAACAAGTTAATT
Streptococcus thermophilus CNRZ1066 str0860 -33 5.5 TATTAACTGGTTAAGT
Streptococcus uberis 0140J SUB0634 -43 5.1 ACTTAACCAGTGAACT
Position: -31
Score: 5.2
Sequence: ACTTAACTGGTTAAAT
Locus tag: M6_Spy1083
M6_Spy1083 -31 5.2 ACTTAACTGGTTAAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: inlA
Ortholog function: Predicted internalin A precursor
Streptococcus agalactiae 2603V/R SAG0907 -45 5.9 AATTAACTAGTTAACT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1372 -50 5.6 AATTAACTAGTTAACC
-30 5.3 GATTAACTGGTTAACT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0679 -48 5.9 AATTAACTAGTTAATA
-28 5.3 ATTTAACTAGTTAATT
Streptococcus pyogenes M1 GAS SPy1361 -31 5.2 ACTTAACCAGTTAAAT
Streptococcus uberis 0140J SUB1212 -33 5.9 AATTAACTAGTTAACA
Position: -84
Score: 5.2
Sequence: ACTTAACCAGTTAAAT
Locus tag: M6_Spy1601
M6_Spy1601 -84 5.2 ACTTAACCAGTTAAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: rpsN2
Ortholog function: Small subunit ribosomal protein S14, zinc-independent
Lactococcus lactis subsp. lactis Il1403 L110165 -42 5.6 ACTTAACTGGTTAACT
Streptococcus agalactiae 2603V/R SAG1754 -137 5 ACTTATCCAGTTAACA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0290 -17 5 TCTTAACTGGTTAATG
Streptococcus gallolyticus UCN34 GALLO_1972 -86 5.3 ATTTAACTAGTTAAGT
Streptococcus pyogenes M1 GAS SPy1871 -84 5.2 ACTTAACCAGTTAAAT
Streptococcus suis 05ZYH33 SSU05_1535 -39 5.9 AATTAACTGGTTAATT
Position: -67
Score: 5.9
Sequence: AATTAACTGGTTAATA
Locus tag: M6_Spy1717
M6_Spy1717 -67 5.9 AATTAACTGGTTAATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: lmb
Ortholog function: Laminin-binding surface lipoprotein
Streptococcus agalactiae 2603V/R SAG1234 -45 5.9 AATTAACTGGTTAATA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0935 -45 5.9 AATTAACTGGTTAATA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1736 -24 5.3 AATTAACCGGTTCATA
Streptococcus pyogenes M1 GAS SPy2007 -45 5.9 AATTAACTGGTTAATA
Streptococcus uberis 0140J SUB0884 -40 5.6 ACTTAACTGGTTAAGT
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