Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of PerR regulog to Streptococcus agalactiae COH1

Reference regulog properties
Source regulog: PerR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: FUR
Regulation mode: repressor
Biological process: Iron homeostasis; Manganese homeostasis; Oxidative stress response
Effector: Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus agalactiae COH1
Orthologous TF(s) SAN_0437, SAN_2375
Regulated genes 6
Built upon 75 sites [see more]
Predicted regulatory interactions in Streptococcus agalactiae COH1
Locus tag Position Score Sequence
Position: -150
Score: 5.7
Sequence: TTATAATGATTTTAA
Locus tag: SAN_1135
SAN_1135 -150 5.7 TTATAATGATTTTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: fatD
Ortholog function: Ferrichrome ABC transporter, permease protein 2
Streptococcus agalactiae 2603V/R SAG1010 -149 5.7 TTATAATGATTTTAA
Streptococcus thermophilus CNRZ1066 str1028 -188 4.8 TTTGATTTATTATAA
-159 4.8 TTATACTTATTCTTA
-136 5.5 TTAGAATGATTCTTA
Position: -122
Score: 5.2
Sequence: TTTGAATCATTCTAA
Position: -37
Score: 4.6
Sequence: TTATAATGAACTTAA
Locus tag: SAN_1500
SAN_1500 -122 5.2 TTTGAATCATTCTAA
-37 4.6 TTATAATGAACTTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: fhuA
Ortholog function: Ferrichrome ABC transporter, ATP-binding protein
Streptococcus agalactiae 2603V/R SAG1392 -122 4.5 TTTGAATCATTCCAA
-37 4.6 TTATAATGAACTTAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0434 -229 4.6 CAAGAATGATTATTA
-207 4.5 TTTTAACCATTCTAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1618 -218 5.4 TGATAATGATTCTAA
Streptococcus gallolyticus UCN34 GALLO_1771 -180 4.8 TTAGAACAATTTTAA
-158 5.2 TTTGAATGATTCTAA
Streptococcus pyogenes M1 GAS SPy0386 -228 4.6 TTAGAATGATTATCG
-206 5.2 TTTTAATCATTCTAA
Streptococcus sanguinis SK36 SSA_1741 -68 4.7 TTAGAAAAATTTTTA
Streptococcus uberis 0140J SUB0424 -133 4.5 TTTTAACCATTCTAA
Position: -79
Score: 5.9
Sequence: TTAGAATGATTATAA
Position: -57
Score: 5.4
Sequence: TTGTAATCATTCTAA
Locus tag: SAN_0894
SAN_0894 -79 5.9 TTAGAATGATTATAA
-57 5.4 TTGTAATCATTCTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pcl
Ortholog function: Predicted membrane protein
Streptococcus agalactiae 2603V/R SAG0798 -79 5.9 TTAGAATGATTATAA
-57 5.4 TTGTAATCATTCTAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1772 -41 5.9 TTATAATGATTATAA
Streptococcus mutans UA159 SMU.635 -37 5.4 TTGTAATCATTCTAA
Streptococcus sanguinis SK36 SSA_0299 -227 5.9 TTATAATCATTATAA
Streptococcus thermophilus CNRZ1066 str0552 -65 4.9 TTGTAATCAATCTAA
-30 5.9 TTATAATGATTCTAA
Position: -28
Score: 5.1
Sequence: TTATATTAATTTTAA
Locus tag: SAN_1639
SAN_1639 -28 5.1 TTATATTAATTTTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: mntA
Ortholog function: Manganese ABC transporter, substrate binding protein
Streptococcus agalactiae 2603V/R SAG1533 -28 5.1 TTATATTAATTTTAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0488 -124 5.6 TTATAATCATTATTA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1469 -124 5.6 TTATAATGATTATTA
Streptococcus gallolyticus UCN34 GALLO_2047 -66 4.8 TTATATTAAATATAA
Streptococcus mutans UA159 SMU.184 -26 4.8 TTATATTACTTATAA
Streptococcus pyogenes M1 GAS SPy0453 -124 5.6 TTATAATGATTATTA
Streptococcus sanguinis SK36 SSA_0260 -54 4.4 TTATATTAATTTTAG
Streptococcus uberis 0140J SUB0473 -123 5.6 TTATAATCATTATTA
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