Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of PerR regulog to Streptococcus suis BM407

Reference regulog properties
Source regulog: PerR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: FUR
Regulation mode: repressor
Biological process: Iron homeostasis; Manganese homeostasis; Oxidative stress response
Effector: Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus suis BM407
Orthologous TF(s) SSUBM407_0280, SSUBM407_0253
Regulated genes 5
Built upon 75 sites [see more]
Predicted regulatory interactions in Streptococcus suis BM407
Locus tag Position Score Sequence
Position: -93
Score: 5.8
Sequence: TTAGAATTATTATAA
Locus tag: SSUBM407_0279
SSUBM407_0279 -93 5.8 TTAGAATTATTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pmtA
Ortholog function: Predicted cation transporting ATPase
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1473 -98 5.5 TTAGAATCGTTCTAA
-65 5.8 TTAGAATTATTATAA
Streptococcus pyogenes M1 GAS SPy1434 -97 5.4 TTAGAATGTTTCTAA
-64 5.8 TTAGAATTATTATAA
Streptococcus suis 05ZYH33 SSU05_0309 -146 5.8 TTAGAATTATTATAA
-114 5.6 TTATAATCGTTATAA
-85 5.2 TGATAATAATTCTAA
Streptococcus uberis 0140J SUB1266 -98 5.8 TTAGAATTATTCTAA
-65 5.4 TTAGAATAGTTATAA
Position: -38
Score: 5.4
Sequence: TTAGAATTTTTATAA
Locus tag: SSUBM407_0280
SSUBM407_0280 -38 5.4 TTAGAATTTTTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: perR
Ortholog function: Peroxide stress response transcriptional regulator PerR, Fur family
Streptococcus gordonii str. Challis substr. CH1 SGO_0703 -74 5 TTACAATCATTCTTA
Streptococcus mutans UA159 SMU.593 -157 4.7 TTTGAATGATTTTTA
Streptococcus sanguinis SK36 SSA_0686 -83 5 TTACAATCATTCTTA
Streptococcus suis 05ZYH33 SSU05_0310 -38 5.4 TTAGAATTTTTATAA
Streptococcus thermophilus CNRZ1066 str0724 -59 5.2 TTATAAATATTTTAA
Position: -119
Score: 4.6
Sequence: TTATAACGATTCTCA
Locus tag: SSUBM407_1217
SSUBM407_1217 -119 4.6 TTATAACGATTCTCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: fhuA
Ortholog function: Ferrichrome ABC transporter, ATP-binding protein
Streptococcus agalactiae 2603V/R SAG1392 -122 4.5 TTTGAATCATTCCAA
-37 4.6 TTATAATGAACTTAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0434 -229 4.6 CAAGAATGATTATTA
-207 4.5 TTTTAACCATTCTAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1618 -218 5.4 TGATAATGATTCTAA
Streptococcus gallolyticus UCN34 GALLO_1771 -180 4.8 TTAGAACAATTTTAA
-158 5.2 TTTGAATGATTCTAA
Streptococcus pyogenes M1 GAS SPy0386 -228 4.6 TTAGAATGATTATCG
-206 5.2 TTTTAATCATTCTAA
Streptococcus sanguinis SK36 SSA_1741 -68 4.7 TTAGAAAAATTTTTA
Streptococcus uberis 0140J SUB0424 -133 4.5 TTTTAACCATTCTAA
Position: -34
Score: 5.9
Sequence: TTATAATTATTATAA
Locus tag: SSUBM407_1574
SSUBM407_1574 -34 5.9 TTATAATTATTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: mgrA
Ortholog function: Non-specific DNA-binding protein / Iron-binding ferritin-like antioxidant protein / Ferroxidase (EC 1.16.3.1)
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1517 -148 4.7 CGAGAATGATTCTAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0585 -136 4.7 CGAGAATGATTCTAA
Streptococcus gallolyticus UCN34 GALLO_0592 -76 5.8 TTAGAATTATTCTAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0665 -73 5.3 TTAGAAGCATTATAA
-37 5.9 TTAGAATGATTATAA
Streptococcus mutans UA159 SMU.540 -57 5.5 TTAGAATCGTTCTAA
Streptococcus pyogenes M1 GAS SPy1531 -157 4.7 CGATAATGATTCTAA
Streptococcus sanguinis SK36 SSA_0644 -71 5.3 TTAGAAGCATTATAA
-35 5.9 TTAGAATCATTATAA
Streptococcus suis 05ZYH33 SSU05_1689 -34 5.9 TTATAATTATTATAA
Streptococcus thermophilus CNRZ1066 str0723 -59 5.2 TTATAAATATTTTAA
Position: 3
Score: 4.2
Sequence: TTAGAATGGATTCAA
Locus tag: SSUBM407_1648
SSUBM407_1648 3 4.2 TTAGAATGGATTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metP
Ortholog function: Methionine ABC transporter, permease protein
Streptococcus suis 05ZYH33 SSU05_1768 -489 4.1 ATACAATGATTGTAA
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