Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of PurR regulog to Lactobacillus rhamnosus HN001

Reference regulog properties
Source regulog: PurR - Lactobacillaceae
Regulator type: Transcription factor
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Phylum: Firmicutes
Propagated regulon:
Target genome Lactobacillus rhamnosus HN001
Orthologous TF(s) LRH_11427
Regulated genes 8
Built upon 76 sites [see more]
Predicted regulatory interactions in Lactobacillus rhamnosus HN001
Locus tag Position Score Sequence
Position: -126
Score: 4.8
Sequence: AAATGCGAACGTT
Locus tag: LRH_11427
LRH_11427 -126 4.8 AAATGCGAACGTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purR
Ortholog function: Purine metabolism transcriptional regulator PurR, PurR family
Lactobacillus acidophilus NCFM LBA0218 -27 4.8 AAAACCAAACATT
Lactobacillus brevis ATCC 367 LVIS_0474 -91 5.3 AAACCCGAACAAT
Lactobacillus casei ATCC 334 LSEI_2587 -126 4.8 AAATGCGAACGTT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_0302 -54 4.3 AAAAACAGACATT
Lactobacillus fermentum IFO 3956 LAF_0194 -98 5.2 AAAGACGAACAAT
Lactobacillus helveticus DPC 4571 lhv_0234 -27 4.1 AAAGCCAAACGTT
Lactobacillus johnsonii NCC 533 LJ0207 -105 4.1 TATTACGAACAAT
Lactobacillus plantarum WCFS1 lp_0466 12 4.3 AGAAGCGAACGTT
Lactobacillus reuteri JCM 1112 LAR_0210 -64 5.2 AAATCCGAACATT
Lactobacillus rhamnosus GG LGG_02564 -126 4.8 AAATGCGAACGTT
Lactobacillus sakei subsp. sakei 23K LSA1651 -120 5.6 AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0315 -116 5.4 AAAAACGAACTTT
Pediococcus pentosaceus ATCC 25745 PEPE_0292 -103 5.2 AAATCCGAACATT
Position: -194
Score: 5.3
Sequence: AAAGACGAACATT
Locus tag: LRH_12459
LRH_12459 -194 5.3 AAAGACGAACATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: guaB
Ortholog function: Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)
Lactobacillus casei ATCC 334 LSEI_0217 -235 4.5 AAAAACGAATGAT
-194 5.3 AAAACCGAACATT
Lactobacillus rhamnosus GG LGG_00249 -194 5.3 AAAGACGAACATT
Lactobacillus sakei subsp. sakei 23K LSA0276 -56 4.9 TAATACGAACATT
Position: -108
Score: 5.6
Sequence: AAACACGAACATT
Position: -96
Score: 4.3
Sequence: TAAAACGAATAAT
Locus tag: LRH_01413
LRH_01413 -108 5.6 AAACACGAACATT
-96 4.3 TAAAACGAATAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purE
Ortholog function: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Lactobacillus acidophilus NCFM LBA1561 -59 4.4 ATATAAGAACAAT
Lactobacillus casei ATCC 334 LSEI_1756 -107 5.3 AAACACGAACGAT
Lactobacillus fermentum IFO 3956 LAF_0118 -106 5.2 AAATCCGAACAAT
Lactobacillus helveticus DPC 4571 lhv_1534 -73 4.1 AAATACAAACAAA
Lactobacillus plantarum WCFS1 lp_2729 -104 5 TAACACGAACATT
Lactobacillus reuteri JCM 1112 LAR_0128 -102 4.9 ATACACGAACTAT
Lactobacillus rhamnosus GG LGG_01814 -108 5.5 AAATACGAACATT
-96 4.3 TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K LSA0652 -112 4.3 TAACACGTACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0515 -68 4.1 AAATTCGAATTTT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 LEUM_0718 -137 4.1 ATATACGAACTCT
Oenococcus oeni PSU-1 OEOE_1138 -130 4.6 AAACACGAAATAT
-79 5.3 AAAAACGAACGTT
Pediococcus pentosaceus ATCC 25745 PEPE_1467 -123 5.4 AAAAACGAACTTT
Position: 4
Score: 3.3
Sequence: AAAAGACCACATT
Locus tag: LRH_01423
LRH_01423 4 3.3 AAAAGACCACATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purC
Ortholog function: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Lactobacillus acidophilus NCFM LBA1559 -151 5.3 AAACACGAACGAT
Lactobacillus casei ATCC 334 LSEI_1754 -107 5.3 AAACACGAACGAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_1338 -60 3.4 AATTACGAATAGT
Lactobacillus fermentum IFO 3956 LAF_0124 -155 5.6 AAACACGAACATT
Lactobacillus plantarum WCFS1 lp_2727 -104 5 TAACACGAACATT
Lactobacillus reuteri JCM 1112 LAR_0131 -153 5.6 AAACACGAACAAT
Lactobacillus rhamnosus GG LGG_01812 -108 5.5 AAATACGAACATT
-96 4.3 TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K LSA0655 -110 4.9 ATAAACGAACTTT
-58 5.6 AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0663 -27 5.2 AAAGACGAACAAT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 LEUM_0720 -137 4.1 ATATACGAACTCT
Oenococcus oeni PSU-1 OEOE_1136 -130 4.6 AAACACGAAATAT
-79 5.3 AAAAACGAACGTT
Pediococcus pentosaceus ATCC 25745 PEPE_1465 -123 5.4 AAAAACGAACTTT
Position: -134
Score: 5.6
Sequence: AAACACGAACATT
Locus tag: LRH_02967
LRH_02967 -134 5.6 AAACACGAACATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: guaC
Ortholog function: GMP reductase (EC 1.7.1.7)
Lactobacillus acidophilus NCFM LBA1893 -120 4.4 AAAACCGAATTAT
Lactobacillus brevis ATCC 367 LVIS_0226 -247 5.3 AAAAGCGAACATT
Lactobacillus casei ATCC 334 LSEI_0911 -135 5.6 AAACACGAACATT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_0246 -111 4.5 AAATCCGAATAAT
-4 5 AAAAATGAACAAT
Lactobacillus johnsonii NCC 533 LJ0441 -160 4.1 AAAACCGAAGACT
Lactobacillus plantarum WCFS1 lp_3271 -280 5.6 AAACACGAACATT
-239 4.5 AGAGACGAACAAT
-135 5.1 AAACAAGAACATT
Lactobacillus rhamnosus GG LGG_00874 -134 5.6 AAACACGAACATT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_1139 -130 5.6 AAACACGAACATT
Oenococcus oeni PSU-1 OEOE_0535 -176 4.1 AAAAACTAACAAG
Pediococcus pentosaceus ATCC 25745 PEPE_0595 -99 4.6 GAAAACGAACTTT
Position: -105
Score: 5.6
Sequence: AAACACGAACATT
Locus tag: LRH_09625
LRH_09625 -105 5.6 AAACACGAACATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pbuO
Ortholog function: Guanine/hypoxanthine permease
Lactobacillus casei ATCC 334 LSEI_0151 -107 5.6 AAACACGAACATT
Lactobacillus rhamnosus GG LGG_00168 -105 5.6 AAACACGAACATT