Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of PurR regulog to Lactobacillus crispatus ST1

Reference regulog properties
Source regulog: PurR - Lactobacillaceae
Regulator type: Transcription factor
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Phylum: Firmicutes
Propagated regulon:
Target genome Lactobacillus crispatus ST1
Orthologous TF(s) LCRIS_00222
Regulated genes 6
Built upon 76 sites [see more]
Predicted regulatory interactions in Lactobacillus crispatus ST1
Locus tag Position Score Sequence
Position: -27
Score: 4.2
Sequence: TAAACCAAACATT
Locus tag: LCRIS_00222
LCRIS_00222 -27 4.2 TAAACCAAACATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purR
Ortholog function: Purine metabolism transcriptional regulator PurR, PurR family
Lactobacillus acidophilus NCFM LBA0218 -27 4.8 AAAACCAAACATT
Lactobacillus brevis ATCC 367 LVIS_0474 -91 5.3 AAACCCGAACAAT
Lactobacillus casei ATCC 334 LSEI_2587 -126 4.8 AAATGCGAACGTT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_0302 -54 4.3 AAAAACAGACATT
Lactobacillus fermentum IFO 3956 LAF_0194 -98 5.2 AAAGACGAACAAT
Lactobacillus helveticus DPC 4571 lhv_0234 -27 4.1 AAAGCCAAACGTT
Lactobacillus johnsonii NCC 533 LJ0207 -105 4.1 TATTACGAACAAT
Lactobacillus plantarum WCFS1 lp_0466 12 4.3 AGAAGCGAACGTT
Lactobacillus reuteri JCM 1112 LAR_0210 -64 5.2 AAATCCGAACATT
Lactobacillus rhamnosus GG LGG_02564 -126 4.8 AAATGCGAACGTT
Lactobacillus sakei subsp. sakei 23K LSA1651 -120 5.6 AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0315 -116 5.4 AAAAACGAACTTT
Pediococcus pentosaceus ATCC 25745 PEPE_0292 -103 5.2 AAATCCGAACATT
Position: -122
Score: 4.9
Sequence: AAAATCGAACTAT
Locus tag: LCRIS_01932
LCRIS_01932 -122 4.9 AAAATCGAACTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purA
Ortholog function: Adenylosuccinate synthetase (EC 6.3.4.4)
Lactobacillus acidophilus NCFM LBA1892 -123 4.9 AAAATCGAACTAT
Lactobacillus brevis ATCC 367 LVIS_0227 -247 5.3 AAAAGCGAACATT
Lactobacillus fermentum IFO 3956 LAF_0044 -123 5.3 AAAACCGAACAAT
Lactobacillus helveticus DPC 4571 lhv_2030 -134 4.9 AAAATCGAACTAT
Lactobacillus johnsonii NCC 533 LJ0442 -120 4.3 AAAAATGAATATT
Lactobacillus plantarum WCFS1 lp_3270 -280 5.6 AAACACGAACATT
-239 4.5 AGAGACGAACAAT
-135 5.1 AAACAAGAACATT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 LEUM_1460 -132 4.2 AAAAAGCAACATT
Pediococcus pentosaceus ATCC 25745 PEPE_1247 -117 5.1 AAACACGAACCAT
Position: -120
Score: 4.2
Sequence: AAATCCGAATTAT
Position: -66
Score: 4.1
Sequence: AAACACAAATTAT
Locus tag: LCRIS_01933
LCRIS_01933 -120 4.2 AAATCCGAATTAT
-66 4.1 AAACACAAATTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: guaC
Ortholog function: GMP reductase (EC 1.7.1.7)
Lactobacillus acidophilus NCFM LBA1893 -120 4.4 AAAACCGAATTAT
Lactobacillus brevis ATCC 367 LVIS_0226 -247 5.3 AAAAGCGAACATT
Lactobacillus casei ATCC 334 LSEI_0911 -135 5.6 AAACACGAACATT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_0246 -111 4.5 AAATCCGAATAAT
-4 5 AAAAATGAACAAT
Lactobacillus johnsonii NCC 533 LJ0441 -160 4.1 AAAACCGAAGACT
Lactobacillus plantarum WCFS1 lp_3271 -280 5.6 AAACACGAACATT
-239 4.5 AGAGACGAACAAT
-135 5.1 AAACAAGAACATT
Lactobacillus rhamnosus GG LGG_00874 -134 5.6 AAACACGAACATT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_1139 -130 5.6 AAACACGAACATT
Oenococcus oeni PSU-1 OEOE_0535 -176 4.1 AAAAACTAACAAG
Pediococcus pentosaceus ATCC 25745 PEPE_0595 -99 4.6 GAAAACGAACTTT
Position: -29
Score: 5.6
Sequence: AAACACGAACAAT
Locus tag: LCRIS_01994
LCRIS_01994 -29 5.6 AAACACGAACAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pbuO
Ortholog function: Guanine/hypoxanthine permease
Lactobacillus acidophilus NCFM LBA1952 -30 5.6 AAACACGAACAAT
Lactobacillus helveticus DPC 4571 lhv_2082 -31 5.6 AAACACGAACATT
Lactobacillus johnsonii NCC 533 LJ1827 -29 5.6 AAAAACGAACATT
Position: 29
Score: 4.8
Sequence: AAAAGAGAACAAT
Locus tag: LCRIS_01997
LCRIS_01997 29 4.8 AAAAGAGAACAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pbuO
Ortholog function: Guanine/hypoxanthine permease
Lactobacillus acidophilus NCFM LBA1956 29 4.4 AAAGGAGAACAAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_2021 -30 4.2 AATTCCGAACGTT
Lactobacillus helveticus DPC 4571 lhv_2087 -96 4.4 AAAATCGAACAAA
Lactobacillus johnsonii NCC 533 LJ1829 -32 5.2 AAATCCGAACATT