Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of PurR regulog to Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Reference regulog properties
Source regulog: PurR - Lactobacillaceae
Regulator type: Transcription factor
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Phylum: Firmicutes
Propagated regulon:
Target genome Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293
Orthologous TF(s) LEUM_1608
Regulated genes 7
Built upon 76 sites [see more]
Predicted regulatory interactions in Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293
Locus tag Position Score Sequence
Position: -154
Score: 3.6
Sequence: CAATCCAAACGTT
Position: -106
Score: 5.3
Sequence: AAAAACGAACTAT
Position: -65
Score: 3.5
Sequence: AAAAACATACAAA
Locus tag: LEUM_0700
LEUM_0700 -154 3.6 CAATCCAAACGTT
-106 5.3 AAAAACGAACTAT
-65 3.5 AAAAACATACAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: purD
Ortholog function: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Lactobacillus acidophilus NCFM LBA1551 -151 5.3 AAACACGAACGAT
Lactobacillus casei ATCC 334 LSEI_1746 -107 5.3 AAACACGAACGAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_1330 -60 3.4 AATTACGAATAGT
Lactobacillus plantarum WCFS1 lp_2719 -104 5 TAACACGAACATT
Lactobacillus reuteri JCM 1112 LAR_0139 -153 5.6 AAACACGAACAAT
Lactobacillus rhamnosus GG LGG_01803 -108 5.5 AAATACGAACATT
-96 4.3 TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K LSA0663 -110 4.9 ATAAACGAACTTT
-58 5.6 AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0671 -27 5.2 AAAGACGAACAAT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 LEUM_0700 -106 5.3 AAAAACGAACTAT
Pediococcus pentosaceus ATCC 25745 PEPE_1457 -123 5.4 AAAAACGAACTTT
Position: -137
Score: 4.1
Sequence: ATATACGAACTCT
Position: -54
Score: 4
Sequence: GTAAACGAACGAT
Locus tag: LEUM_0718
LEUM_0718 -137 4.1 ATATACGAACTCT
-54 4 GTAAACGAACGAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purE
Ortholog function: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Lactobacillus acidophilus NCFM LBA1561 -59 4.4 ATATAAGAACAAT
Lactobacillus casei ATCC 334 LSEI_1756 -107 5.3 AAACACGAACGAT
Lactobacillus fermentum IFO 3956 LAF_0118 -106 5.2 AAATCCGAACAAT
Lactobacillus helveticus DPC 4571 lhv_1534 -73 4.1 AAATACAAACAAA
Lactobacillus plantarum WCFS1 lp_2729 -104 5 TAACACGAACATT
Lactobacillus reuteri JCM 1112 LAR_0128 -102 4.9 ATACACGAACTAT
Lactobacillus rhamnosus GG LGG_01814 -108 5.5 AAATACGAACATT
-96 4.3 TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K LSA0652 -112 4.3 TAACACGTACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0515 -68 4.1 AAATTCGAATTTT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 LEUM_0718 -137 4.1 ATATACGAACTCT
Oenococcus oeni PSU-1 OEOE_1138 -130 4.6 AAACACGAAATAT
-79 5.3 AAAAACGAACGTT
Pediococcus pentosaceus ATCC 25745 PEPE_1467 -123 5.4 AAAAACGAACTTT
Position: 6
Score: 3.3
Sequence: ACAAATGAATTAT
Locus tag: LEUM_0723
LEUM_0723 6 3.3 ACAAATGAATTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purL
Ortholog function: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
Lactobacillus acidophilus NCFM LBA1556 -151 5.3 AAACACGAACGAT
Lactobacillus casei ATCC 334 LSEI_1751 -107 5.3 AAACACGAACGAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_1335 -60 3.4 AATTACGAATAGT
Lactobacillus fermentum IFO 3956 LAF_0127 -155 5.6 AAACACGAACATT
Lactobacillus plantarum WCFS1 lp_2724 -104 5 TAACACGAACATT
Lactobacillus reuteri JCM 1112 LAR_0134 -153 5.6 AAACACGAACAAT
Lactobacillus rhamnosus GG LGG_01809 -108 5.5 AAATACGAACATT
-96 4.3 TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K LSA0658 -110 4.9 ATAAACGAACTTT
-58 5.6 AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0666 -27 5.2 AAAGACGAACAAT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 LEUM_0723 -137 4.1 ATATACGAACTCT
Oenococcus oeni PSU-1 OEOE_1133 -130 4.6 AAACACGAAATAT
-79 5.3 AAAAACGAACGTT
Pediococcus pentosaceus ATCC 25745 PEPE_1462 -123 5.4 AAAAACGAACTTT
Position: 27
Score: 3.6
Sequence: ATGAACGAACAAA
Locus tag: LEUM_0724
LEUM_0724 27 3.6 ATGAACGAACAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: purF
Ortholog function: Amidophosphoribosyltransferase (EC 2.4.2.14)
Lactobacillus acidophilus NCFM LBA1555 -151 5.3 AAACACGAACGAT
Lactobacillus casei ATCC 334 LSEI_1750 -107 5.3 AAACACGAACGAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_1334 -60 3.4 AATTACGAATAGT
Lactobacillus fermentum IFO 3956 LAF_0128 -155 5.6 AAACACGAACATT
Lactobacillus plantarum WCFS1 lp_2723 -104 5 TAACACGAACATT
Lactobacillus reuteri JCM 1112 LAR_0135 -153 5.6 AAACACGAACAAT
Lactobacillus rhamnosus GG LGG_01808 -108 5.5 AAATACGAACATT
-96 4.3 TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K LSA0659 -110 4.9 ATAAACGAACTTT
-58 5.6 AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0667 -27 5.2 AAAGACGAACAAT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 LEUM_0724 -137 4.1 ATATACGAACTCT
Pediococcus pentosaceus ATCC 25745 PEPE_1461 -123 5.4 AAAAACGAACTTT
Position: -132
Score: 4.2
Sequence: AAAAAGCAACATT
Locus tag: LEUM_1460
LEUM_1460 -132 4.2 AAAAAGCAACATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purA
Ortholog function: Adenylosuccinate synthetase (EC 6.3.4.4)
Lactobacillus acidophilus NCFM LBA1892 -123 4.9 AAAATCGAACTAT
Lactobacillus brevis ATCC 367 LVIS_0227 -247 5.3 AAAAGCGAACATT
Lactobacillus fermentum IFO 3956 LAF_0044 -123 5.3 AAAACCGAACAAT
Lactobacillus helveticus DPC 4571 lhv_2030 -134 4.9 AAAATCGAACTAT
Lactobacillus johnsonii NCC 533 LJ0442 -120 4.3 AAAAATGAATATT
Lactobacillus plantarum WCFS1 lp_3270 -280 5.6 AAACACGAACATT
-239 4.5 AGAGACGAACAAT
-135 5.1 AAACAAGAACATT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 LEUM_1460 -132 4.2 AAAAAGCAACATT
Pediococcus pentosaceus ATCC 25745 PEPE_1247 -117 5.1 AAACACGAACCAT
Position: -52
Score: 4.3
Sequence: AAACATGAGCAAT
Locus tag: LEUM_1607
LEUM_1607 -52 4.3 AAACATGAGCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: glmU
Ortholog function: N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) / Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)
Lactobacillus acidophilus NCFM LBA0219 -27 4.8 AAAACCAAACATT
Lactobacillus brevis ATCC 367 LVIS_0475 -91 5.3 AAACCCGAACAAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_0303 -54 4.3 AAAAACAGACATT
Lactobacillus fermentum IFO 3956 LAF_0195 -98 5.2 AAAGACGAACAAT
Lactobacillus helveticus DPC 4571 lhv_0235 -27 4.1 AAAGCCAAACGTT
Lactobacillus johnsonii NCC 533 LJ0208 -105 4.1 TATTACGAACAAT
Lactobacillus plantarum WCFS1 lp_0467 12 4.3 AGAAGCGAACGTT
Lactobacillus reuteri JCM 1112 LAR_0211 -64 5.2 AAATCCGAACATT
Lactobacillus sakei subsp. sakei 23K LSA1648 -24 4.2 AATCACGAATATT
Pediococcus pentosaceus ATCC 25745 PEPE_0293 -103 5.2 AAATCCGAACATT