Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of PurR regulog to Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365

Reference regulog properties
Source regulog: PurR - Lactobacillaceae
Regulator type: Transcription factor
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Phylum: Firmicutes
Propagated regulon:
Target genome Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
Orthologous TF(s) LBUL_0302
Regulated genes 7
Built upon 76 sites [see more]
Predicted regulatory interactions in Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
Locus tag Position Score Sequence
Position: -111
Score: 4.5
Sequence: AAATCCGAATAAT
Position: -4
Score: 5
Sequence: AAAAATGAACAAT
Locus tag: LBUL_0246
LBUL_0246 -111 4.5 AAATCCGAATAAT
-4 5 AAAAATGAACAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: guaC
Ortholog function: GMP reductase (EC 1.7.1.7)
Lactobacillus acidophilus NCFM LBA1893 -120 4.4 AAAACCGAATTAT
Lactobacillus brevis ATCC 367 LVIS_0226 -247 5.3 AAAAGCGAACATT
Lactobacillus casei ATCC 334 LSEI_0911 -135 5.6 AAACACGAACATT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_0246 -111 4.5 AAATCCGAATAAT
-4 5 AAAAATGAACAAT
Lactobacillus johnsonii NCC 533 LJ0441 -160 4.1 AAAACCGAAGACT
Lactobacillus plantarum WCFS1 lp_3271 -280 5.6 AAACACGAACATT
-239 4.5 AGAGACGAACAAT
-135 5.1 AAACAAGAACATT
Lactobacillus rhamnosus GG LGG_00874 -134 5.6 AAACACGAACATT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_1139 -130 5.6 AAACACGAACATT
Oenococcus oeni PSU-1 OEOE_0535 -176 4.1 AAAAACTAACAAG
Pediococcus pentosaceus ATCC 25745 PEPE_0595 -99 4.6 GAAAACGAACTTT
Position: -54
Score: 4.3
Sequence: AAAAACAGACATT
Locus tag: LBUL_0302
LBUL_0302 -54 4.3 AAAAACAGACATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purR
Ortholog function: Purine metabolism transcriptional regulator PurR, PurR family
Lactobacillus acidophilus NCFM LBA0218 -27 4.8 AAAACCAAACATT
Lactobacillus brevis ATCC 367 LVIS_0474 -91 5.3 AAACCCGAACAAT
Lactobacillus casei ATCC 334 LSEI_2587 -126 4.8 AAATGCGAACGTT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_0302 -54 4.3 AAAAACAGACATT
Lactobacillus fermentum IFO 3956 LAF_0194 -98 5.2 AAAGACGAACAAT
Lactobacillus helveticus DPC 4571 lhv_0234 -27 4.1 AAAGCCAAACGTT
Lactobacillus johnsonii NCC 533 LJ0207 -105 4.1 TATTACGAACAAT
Lactobacillus plantarum WCFS1 lp_0466 12 4.3 AGAAGCGAACGTT
Lactobacillus reuteri JCM 1112 LAR_0210 -64 5.2 AAATCCGAACATT
Lactobacillus rhamnosus GG LGG_02564 -126 4.8 AAATGCGAACGTT
Lactobacillus sakei subsp. sakei 23K LSA1651 -120 5.6 AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0315 -116 5.4 AAAAACGAACTTT
Pediococcus pentosaceus ATCC 25745 PEPE_0292 -103 5.2 AAATCCGAACATT
Position: 26
Score: 3.6
Sequence: AGACAAGAACAAC
Locus tag: LBUL_1331
LBUL_1331 26 3.6 AGACAAGAACAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: purH
Ortholog function: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Lactobacillus acidophilus NCFM LBA1552 -151 5.3 AAACACGAACGAT
Lactobacillus casei ATCC 334 LSEI_1747 -107 5.3 AAACACGAACGAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_1331 -60 3.4 AATTACGAATAGT
Lactobacillus fermentum IFO 3956 LAF_0131 -155 5.6 AAACACGAACATT
Lactobacillus plantarum WCFS1 lp_2720 -104 5 TAACACGAACATT
Lactobacillus reuteri JCM 1112 LAR_0138 -153 5.6 AAACACGAACAAT
Lactobacillus rhamnosus GG LGG_01805 -108 5.5 AAATACGAACATT
-96 4.3 TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K LSA0662 -110 4.9 ATAAACGAACTTT
-58 5.6 AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0670 -27 5.2 AAAGACGAACAAT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 LEUM_0727 -137 4.1 ATATACGAACTCT
Pediococcus pentosaceus ATCC 25745 PEPE_1458 -123 5.4 AAAAACGAACTTT
Position: -256
Score: 3.3
Sequence: AAAAGCGACTCAT
Position: -60
Score: 3.4
Sequence: AATTACGAATAGT
Locus tag: LBUL_1338
LBUL_1338 -256 3.3 AAAAGCGACTCAT
-60 3.4 AATTACGAATAGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purC
Ortholog function: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Lactobacillus acidophilus NCFM LBA1559 -151 5.3 AAACACGAACGAT
Lactobacillus casei ATCC 334 LSEI_1754 -107 5.3 AAACACGAACGAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_1338 -60 3.4 AATTACGAATAGT
Lactobacillus fermentum IFO 3956 LAF_0124 -155 5.6 AAACACGAACATT
Lactobacillus plantarum WCFS1 lp_2727 -104 5 TAACACGAACATT
Lactobacillus reuteri JCM 1112 LAR_0131 -153 5.6 AAACACGAACAAT
Lactobacillus rhamnosus GG LGG_01812 -108 5.5 AAATACGAACATT
-96 4.3 TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K LSA0655 -110 4.9 ATAAACGAACTTT
-58 5.6 AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0663 -27 5.2 AAAGACGAACAAT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 LEUM_0720 -137 4.1 ATATACGAACTCT
Oenococcus oeni PSU-1 OEOE_1136 -130 4.6 AAACACGAAATAT
-79 5.3 AAAAACGAACGTT
Pediococcus pentosaceus ATCC 25745 PEPE_1465 -123 5.4 AAAAACGAACTTT
Position: -30
Score: 4.2
Sequence: AATTCCGAACGTT
Locus tag: LBUL_2021
LBUL_2021 -30 4.2 AATTCCGAACGTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pbuO
Ortholog function: Guanine/hypoxanthine permease
Lactobacillus acidophilus NCFM LBA1956 29 4.4 AAAGGAGAACAAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_2021 -30 4.2 AATTCCGAACGTT
Lactobacillus helveticus DPC 4571 lhv_2087 -96 4.4 AAAATCGAACAAA
Lactobacillus johnsonii NCC 533 LJ1829 -32 5.2 AAATCCGAACATT