Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of PurR regulog to Lactobacillus plantarum WCFS1

Reference regulog properties
Source regulog: PurR - Lactobacillaceae
Regulator type: Transcription factor
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Phylum: Firmicutes
Propagated regulon:
Target genome Lactobacillus plantarum WCFS1
Orthologous TF(s) lp_0466
Regulated genes 8
Built upon 76 sites [see more]
Predicted regulatory interactions in Lactobacillus plantarum WCFS1
Locus tag Position Score Sequence
Position: 12
Score: 4.3
Sequence: AGAAGCGAACGTT
Locus tag: lp_0466
lp_0466 12 4.3 AGAAGCGAACGTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purR
Ortholog function: Purine metabolism transcriptional regulator PurR, PurR family
Lactobacillus acidophilus NCFM LBA0218 -27 4.8 AAAACCAAACATT
Lactobacillus brevis ATCC 367 LVIS_0474 -91 5.3 AAACCCGAACAAT
Lactobacillus casei ATCC 334 LSEI_2587 -126 4.8 AAATGCGAACGTT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_0302 -54 4.3 AAAAACAGACATT
Lactobacillus fermentum IFO 3956 LAF_0194 -98 5.2 AAAGACGAACAAT
Lactobacillus helveticus DPC 4571 lhv_0234 -27 4.1 AAAGCCAAACGTT
Lactobacillus johnsonii NCC 533 LJ0207 -105 4.1 TATTACGAACAAT
Lactobacillus plantarum WCFS1 lp_0466 12 4.3 AGAAGCGAACGTT
Lactobacillus reuteri JCM 1112 LAR_0210 -64 5.2 AAATCCGAACATT
Lactobacillus rhamnosus GG LGG_02564 -126 4.8 AAATGCGAACGTT
Lactobacillus sakei subsp. sakei 23K LSA1651 -120 5.6 AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0315 -116 5.4 AAAAACGAACTTT
Pediococcus pentosaceus ATCC 25745 PEPE_0292 -103 5.2 AAATCCGAACATT
Position: -57
Score: 5.3
Sequence: AAACACGAACGTT
Locus tag: lp_0848
lp_0848 -57 5.3 AAACACGAACGTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pbuG
Ortholog function: Guanine/hypoxanthine permease
Lactobacillus brevis ATCC 367 LVIS_2274 -66 5.6 AAACACGAACAAT
Lactobacillus fermentum IFO 3956 LAF_1806 -67 4.3 AAAGCCGAATATT
Lactobacillus plantarum WCFS1 lp_0848 -57 5.3 AAACACGAACGTT
Pediococcus pentosaceus ATCC 25745 PEPE_0303 -122 5.2 AAATACGAACTAT
Position: 28
Score: 3.4
Sequence: ATAAGCAATCAAT
Locus tag: lp_2726
lp_2726 28 3.4 ATAAGCAATCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purS
Ortholog function: Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
Lactobacillus acidophilus NCFM LBA1558 -151 5.3 AAACACGAACGAT
Lactobacillus casei ATCC 334 LSEI_1753 -107 5.3 AAACACGAACGAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_1337 -60 3.4 AATTACGAATAGT
Lactobacillus fermentum IFO 3956 LAF_0125 -155 5.6 AAACACGAACATT
Lactobacillus plantarum WCFS1 lp_2726 -104 5 TAACACGAACATT
Lactobacillus reuteri JCM 1112 LAR_0132 -153 5.6 AAACACGAACAAT
Lactobacillus rhamnosus GG LGG_01811 -108 5.5 AAATACGAACATT
-96 4.3 TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K LSA0656 -110 4.9 ATAAACGAACTTT
-58 5.6 AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0664 -27 5.2 AAAGACGAACAAT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 LEUM_0721 -137 4.1 ATATACGAACTCT
Oenococcus oeni PSU-1 OEOE_1135 -130 4.6 AAACACGAAATAT
-79 5.3 AAAAACGAACGTT
Pediococcus pentosaceus ATCC 25745 PEPE_1464 -123 5.4 AAAAACGAACTTT
Position: 16
Score: 3.3
Sequence: AGAAACAAGCTTT
Locus tag: lp_2727
lp_2727 16 3.3 AGAAACAAGCTTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purC
Ortholog function: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Lactobacillus acidophilus NCFM LBA1559 -151 5.3 AAACACGAACGAT
Lactobacillus casei ATCC 334 LSEI_1754 -107 5.3 AAACACGAACGAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_1338 -60 3.4 AATTACGAATAGT
Lactobacillus fermentum IFO 3956 LAF_0124 -155 5.6 AAACACGAACATT
Lactobacillus plantarum WCFS1 lp_2727 -104 5 TAACACGAACATT
Lactobacillus reuteri JCM 1112 LAR_0131 -153 5.6 AAACACGAACAAT
Lactobacillus rhamnosus GG LGG_01812 -108 5.5 AAATACGAACATT
-96 4.3 TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K LSA0655 -110 4.9 ATAAACGAACTTT
-58 5.6 AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0663 -27 5.2 AAAGACGAACAAT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 LEUM_0720 -137 4.1 ATATACGAACTCT
Oenococcus oeni PSU-1 OEOE_1136 -130 4.6 AAACACGAAATAT
-79 5.3 AAAAACGAACGTT
Pediococcus pentosaceus ATCC 25745 PEPE_1465 -123 5.4 AAAAACGAACTTT
Position: -104
Score: 5
Sequence: TAACACGAACATT
Locus tag: lp_2729
lp_2729 -104 5 TAACACGAACATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purE
Ortholog function: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Lactobacillus acidophilus NCFM LBA1561 -59 4.4 ATATAAGAACAAT
Lactobacillus casei ATCC 334 LSEI_1756 -107 5.3 AAACACGAACGAT
Lactobacillus fermentum IFO 3956 LAF_0118 -106 5.2 AAATCCGAACAAT
Lactobacillus helveticus DPC 4571 lhv_1534 -73 4.1 AAATACAAACAAA
Lactobacillus plantarum WCFS1 lp_2729 -104 5 TAACACGAACATT
Lactobacillus reuteri JCM 1112 LAR_0128 -102 4.9 ATACACGAACTAT
Lactobacillus rhamnosus GG LGG_01814 -108 5.5 AAATACGAACATT
-96 4.3 TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K LSA0652 -112 4.3 TAACACGTACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0515 -68 4.1 AAATTCGAATTTT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 LEUM_0718 -137 4.1 ATATACGAACTCT
Oenococcus oeni PSU-1 OEOE_1138 -130 4.6 AAACACGAAATAT
-79 5.3 AAAAACGAACGTT
Pediococcus pentosaceus ATCC 25745 PEPE_1467 -123 5.4 AAAAACGAACTTT
Position: -201
Score: 4.3
Sequence: AAAACCGAATGTT
Locus tag: lp_3269
lp_3269 -201 4.3 AAAACCGAATGTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purB
Ortholog function: Adenylosuccinate lyase (EC 4.3.2.2)
Lactobacillus acidophilus NCFM LBA1891 -123 4.9 AAAATCGAACTAT
Lactobacillus brevis ATCC 367 LVIS_0228 -190 5 AAAAGCGAACTAT
Lactobacillus fermentum IFO 3956 LAF_0120 -106 5.2 AAATCCGAACAAT
Lactobacillus helveticus DPC 4571 lhv_2029 -134 4.9 AAAATCGAACTAT
Lactobacillus johnsonii NCC 533 LJ0443 -120 4.3 AAAAATGAATATT
Lactobacillus plantarum WCFS1 lp_3269 -201 4.3 AAAACCGAATGTT
Lactobacillus reuteri JCM 1112 LAR_0130 -102 4.9 ATACACGAACTAT
Lactobacillus sakei subsp. sakei 23K LSA0654 -112 4.3 TAACACGTACAAT
Lactobacillus salivarius subsp. salivarius UCC118 LSL_0517 -68 4.1 AAATTCGAATTTT
Position: -280
Score: 5.6
Sequence: AAACACGAACATT
Position: -239
Score: 4.5
Sequence: AGAGACGAACAAT
Position: -135
Score: 5.1
Sequence: AAACAAGAACATT
Locus tag: lp_3270
lp_3270 -280 5.6 AAACACGAACATT
-239 4.5 AGAGACGAACAAT
-135 5.1 AAACAAGAACATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purA
Ortholog function: Adenylosuccinate synthetase (EC 6.3.4.4)
Lactobacillus acidophilus NCFM LBA1892 -123 4.9 AAAATCGAACTAT
Lactobacillus brevis ATCC 367 LVIS_0227 -247 5.3 AAAAGCGAACATT
Lactobacillus fermentum IFO 3956 LAF_0044 -123 5.3 AAAACCGAACAAT
Lactobacillus helveticus DPC 4571 lhv_2030 -134 4.9 AAAATCGAACTAT
Lactobacillus johnsonii NCC 533 LJ0442 -120 4.3 AAAAATGAATATT
Lactobacillus plantarum WCFS1 lp_3270 -280 5.6 AAACACGAACATT
-239 4.5 AGAGACGAACAAT
-135 5.1 AAACAAGAACATT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 LEUM_1460 -132 4.2 AAAAAGCAACATT
Pediococcus pentosaceus ATCC 25745 PEPE_1247 -117 5.1 AAACACGAACCAT