Propagation of McbR regulog to Corynebacterium diphtheriae NCTC 13129

Reference regulog properties
Source regulog:	McbR - Corynebacteriaceae
Regulator type:	Transcription factor
Regulator family:	TetR
Regulation mode:	repressor
Biological process:	Methionine biosynthesis
Effector:	S-adenosylmethionine; S-adenosylhomocysteine
Phylum:	Actinobacteria
Propagated regulon:
Target genome	Corynebacterium diphtheriae NCTC 13129
Orthologous TF(s)	DIP2274
Regulated genes	10

Built upon 162 sites [see more]

Predicted regulatory interactions in *Corynebacterium diphtheriae NCTC 13129*
	Locus tag	Position	Score	Sequence
Position: -126 Score: 4.6 Sequence: CGTACCGATCGGTCTA Locus tag: DIP0123
	DIP0123	-126	4.6	CGTACCGATCGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysR
Ortholog function: Sulphur metabolism transcriptional regulator CysR, ROK family
Corynebacterium aurimucosum ATCC 700975	cauri_0079	-40	4.5	TAGACCATGATGTCTA
		-6	4.7	TAGACAATGCGGTCTG
Corynebacterium diphtheriae NCTC 13129	DIP0123	-126	4.6	CGTACCGATCGGTCTA
		-37	4.4	TAGACAAGCTGGTCTA
Corynebacterium glutamicum ATCC 13032	cg0156	-69	4.8	CAGACAATGCGGTCTA
		-36	5.4	TAGACAGCGTTGTCTA

Position: -76 Score: 4.7 Sequence: TAGACCGAGCTGTACA Locus tag: DIP0610
	DIP0610	-76	4.7	TAGACCGAGCTGTACA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metQ
Ortholog function: Methionine ABC transporter substrate-binding protein
Corynebacterium diphtheriae NCTC 13129	DIP0610	-76	4.7	TAGACCGAGCTGTACA

Position: -166 Score: 4.7 Sequence: TAGACAAAGCTGTACA Locus tag: DIP0611
	DIP0611	-166	4.7	TAGACAAAGCTGTACA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metQ
Ortholog function: Methionine ABC transporter substrate-binding protein
Corynebacterium amycolatum SK46	CORAM0001_0284	-70	5	AAGACAGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP0611	-166	4.7	TAGACAAAGCTGTACA
Corynebacterium efficiens YS-314	CE0631	-94	4.7	TAGACCGAGCTGTACA
Corynebacterium glutamicum ATCC 13032	cg0737	-109	4.6	TAGACCAAGCTGTACA

Position: -60 Score: 5.2 Sequence: TAGACAGAGCTGTCCA Locus tag: DIP0623
	DIP0623	-60	5.2	TAGACAGAGCTGTCCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metX
Ortholog function: Homoserine O-acetyltransferase (EC 2.3.1.31)
Corynebacterium amycolatum SK46	CORAM0001_0290	-22	4.3	CGGACTAAGTAGTCTA
Corynebacterium aurimucosum ATCC 700975	cauri_0512	-92	4.2	CCAACCGCTCGGTCTA
		-27	4.8	TGAACCGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP0623	-60	5.2	TAGACAGAGCTGTCCA
Corynebacterium efficiens YS-314	CE0678	-139	4.6	CGAACCGCTCGGTCTA
		-117	4.9	TAGACCGAGCGGTTCA
Corynebacterium glutamicum ATCC 13032	cg0754	-69	5.2	TAGACAGAGCTGTCCA
Corynebacterium jeikeium K411	jk1695	-171	4.5	TAGACCAAGCGGTATG
		-93	5.2	TAGACAGAGCGGTTTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1569	-300	4.6	CATACCGCTTAGTCTA
		-244	4.4	TAGACAGGGCGGTTTG
		-225	4.8	TAGACCGAGCGGTACA
Corynebacterium urealyticum DSM 7109	cur_0422	-212	4.9	TAGACCAAGTGGTATA
		-145	5.2	TAGACAGAGCGGTTTA

Position: -82 Score: 4.6 Sequence: TAGACCGATCGGTTTC Locus tag: DIP0630
	DIP0630	-82	4.6	TAGACCGATCGGTTTC
Supported by regulated orthologs from reference regulons
Ortholog gene name: metY
Ortholog function: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Corynebacterium amycolatum SK46	CORAM0001_0291	-73	5	TAGACAGCTTGGTTCA
Corynebacterium aurimucosum ATCC 700975	cauri_0513	-92	4.2	CCAACCGCTCGGTCTA
		-27	4.8	TGAACCGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP0630	-138	4.1	CGCACCACTTTGTCTA
		-82	4.6	TAGACCGATCGGTTTC
Corynebacterium efficiens YS-314	CE0679	-139	4.6	CGAACCGCTCGGTCTA
		-117	4.9	TAGACCGAGCGGTTCA
Corynebacterium glutamicum ATCC 13032	cg0755	-90	4.5	TATACCACACAGTCTA
		-68	4.7	TAGACCAAGCTGTTCA
Corynebacterium jeikeium K411	jk1694	-171	4.5	TAGACCAAGCGGTATG
		-93	5.2	TAGACAGAGCGGTTTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1568	-300	4.6	CATACCGCTTAGTCTA
		-244	4.4	TAGACAGGGCGGTTTG
		-225	4.8	TAGACCGAGCGGTACA
Corynebacterium urealyticum DSM 7109	cur_0423	-212	4.9	TAGACCAAGTGGTATA
		-145	5.2	TAGACAGAGCGGTTTA

Position: -17 Score: 4.5 Sequence: CATACTAAGCTGTCTA Locus tag: DIP1259
	DIP1259	-17	4.5	CATACTAAGCTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metH
Ortholog function: 5-methyltetrahydrofolate-homocysteine methyltransferase (EC 2.1.1.13)
Corynebacterium amycolatum SK46	CORAM0001_0986	-19	4.6	TAGACTAAGGTGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP1259	-17	4.5	CATACTAAGCTGTCTA
Corynebacterium efficiens YS-314	CE1637	-20	4.2	CGTACTAAGCTGTCTA
Corynebacterium glutamicum ATCC 13032	cg1701	-95	4.2	CGTACTAAGCTGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0919	20	5.1	TAGACTAAGCTGTCTA

Position: -116 Score: 5.5 Sequence: TAGACAGCTTGGTCTA Locus tag: DIP1325
	DIP1325	-116	5.5	TAGACAGCTTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metK
Ortholog function: S-adenosylmethionine synthetase (EC 2.5.1.6)
Corynebacterium amycolatum SK46	CORAM0001_0910	-98	4.8	TGAACCGCTTGGTCTA
Corynebacterium aurimucosum ATCC 700975	cauri_1185	-97	5.4	TAGACCGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP1325	-116	5.5	TAGACAGCTTGGTCTA
Corynebacterium efficiens YS-314	CE1723	-73	5.5	TAGACAGCTTGGTCTA
Corynebacterium glutamicum ATCC 13032	cg1806	-74	5.5	TAGACAGCTTGGTCTA
Corynebacterium jeikeium K411	jk1016	-75	5.2	CAGACAGCTTGGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0984	-98	5.5	TAGACAGCTTGGTCTA
Corynebacterium urealyticum DSM 7109	cur_0975	-110	5.4	TAGACCGCTTGGTCTA

Position: -152 Score: 4.5 Sequence: TAGACCGATCGGTACG Position: -130 Score: 4.6 Sequence: AAGACAATTCTGTCTA Locus tag: DIP1890
	DIP1890	-152	4.5	TAGACCGATCGGTACG
		-130	4.6	AAGACAATTCTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysK
Ortholog function: Cysteine synthase (EC 2.5.1.47)
Corynebacterium amycolatum SK46	CORAM0001_2226	-103	3.9	TAGACGAACTGGTCTG
Corynebacterium aurimucosum ATCC 700975	cauri_2144	-74	4.8	TATACCACTCAGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP1890	-152	4.5	TAGACCGATCGGTACG
		-130	4.6	AAGACAATTCTGTCTA
Corynebacterium efficiens YS-314	CE2446	-148	4.7	TAGACCGATCCGTCTG
Corynebacterium glutamicum ATCC 13032	cg2833	-150	4.6	TGAACAGAACTGTCTA
Corynebacterium jeikeium K411	jk0394	-35	5.2	TAGACCGATCAGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0419	-152	4.8	CAGACCGATCTGTCTG
Corynebacterium urealyticum DSM 7109	cur_1592	-60	5.3	TAGACAGATCAGTCTA

Position: -74 Score: 4.7 Sequence: TAGACTGATCTGTTCA Locus tag: DIP2274
	DIP2274	-74	4.7	TAGACTGATCTGTTCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: mcbR
Ortholog function: Methionine biosynthesis transcriptional regulator McbR, TetR family
Corynebacterium aurimucosum ATCC 700975	cauri_2422	-57	4.4	CATACCGGTTTGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP2274	-74	4.7	TAGACTGATCTGTTCA
Corynebacterium efficiens YS-314	CE2788	-154	4.1	CGAACCGGTTTGTCTA
Corynebacterium glutamicum ATCC 13032	cg3253	-78	4.1	CGAACCGGTTTGTCTA

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of McbR regulog to Corynebacterium diphtheriae NCTC 13129

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --