Propagation of McbR regulog to Corynebacterium urealyticum DSM 7109

Reference regulog properties
Source regulog:	McbR - Corynebacteriaceae
Regulator type:	Transcription factor
Regulator family:	TetR
Regulation mode:	repressor
Biological process:	Methionine biosynthesis
Effector:	S-adenosylmethionine; S-adenosylhomocysteine
Phylum:	Actinobacteria
Propagated regulon:
Target genome	Corynebacterium urealyticum DSM 7109
Orthologous TF(s)	cur_0113
Regulated genes	13

Built upon 162 sites [see more]

Predicted regulatory interactions in *Corynebacterium urealyticum DSM 7109*
	Locus tag	Position	Score	Sequence
Position: -183 Score: 4.8 Sequence: TAGACCGCATGGTCTG Position: -105 Score: 4.6 Sequence: TAGACAGTTCGGTATG Position: -39 Score: 5 Sequence: TAGACAGATCGGTTCA Locus tag: cur_0176
	cur_0176	-183	4.8	TAGACCGCATGGTCTG
		-105	4.6	TAGACAGTTCGGTATG
		-39	5	TAGACAGATCGGTTCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: CE2728
Ortholog function: Predicted permease protein
Corynebacterium amycolatum SK46	CORAM0001_2013	-163	4	TATACGGTTCGGTCTG
		-65	4.6	TAGACAGGTCTGTTCA
Corynebacterium efficiens YS-314	CE2728	-99	4.9	TAGACCTCTCTGTCTA
Corynebacterium jeikeium K411	jk0156	-41	4.7	CAGACAGATCGGTTCA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0159	-153	5.6	TAGACAGATCGGTCTA
Corynebacterium urealyticum DSM 7109	cur_0176	-183	4.8	TAGACCGCATGGTCTG
		-105	4.6	TAGACAGTTCGGTATG
		-39	5	TAGACAGATCGGTTCA

Position: -41 Score: 5 Sequence: TAGACAGATCTGTTCA Locus tag: cur_0251
	cur_0251	-41	5	TAGACAGATCTGTTCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cg2678
Ortholog function: Predicted ABC transporter, substrate-binding protein
Corynebacterium aurimucosum ATCC 700975	cauri_2043	-36	5	TAGACTGTGCTGTCTA
Corynebacterium efficiens YS-314	CE2334	-71	5.5	TAGACAGATTGGTCTA
		-48	4.2	AGTACCGATCAGTCTA
Corynebacterium glutamicum ATCC 13032	cg2678	-112	4.8	TAGACAGGTTGGTCTG
		-90	4.9	TATACCGATCAGTCTA
Corynebacterium urealyticum DSM 7109	cur_0251	-41	5	TAGACAGATCTGTTCA

Position: -61 Score: 4.9 Sequence: TGAACAGATCTGTCTA Locus tag: cur_0252
	cur_0252	-61	4.9	TGAACAGATCTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cg2679
Ortholog function: Conserved hypothetical protein
Corynebacterium aurimucosum ATCC 700975	cauri_2044	-36	5	TAGACAGCACAGTCTA
Corynebacterium efficiens YS-314	CE2335	-75	4.1	TAGACTGATCGGTACT
		-52	5.3	TAGACCAATCTGTCTA
Corynebacterium glutamicum ATCC 13032	cg2679	-72	5	TAGACTGATCGGTATA
		-50	4.4	CAGACCAACCTGTCTA
Corynebacterium urealyticum DSM 7109	cur_0252	-61	4.9	TGAACAGATCTGTCTA

Position: -127 Score: 4.9 Sequence: TAGACCAAGTTGTCCA Locus tag: cur_0411
	cur_0411	-127	4.9	TAGACCAAGTTGTCCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metQ
Ortholog function: Methionine ABC transporter substrate-binding protein
Corynebacterium jeikeium K411	jk1710	-103	4.5	TAGACTAAGTTGTTCA
Corynebacterium urealyticum DSM 7109	cur_0411	-127	4.9	TAGACCAAGTTGTCCA

Position: -212 Score: 4.9 Sequence: TAGACCAAGTGGTATA Position: -145 Score: 5.2 Sequence: TAGACAGAGCGGTTTA Locus tag: cur_0423
	cur_0423	-212	4.9	TAGACCAAGTGGTATA
		-145	5.2	TAGACAGAGCGGTTTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metY
Ortholog function: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Corynebacterium amycolatum SK46	CORAM0001_0291	-73	5	TAGACAGCTTGGTTCA
Corynebacterium aurimucosum ATCC 700975	cauri_0513	-92	4.2	CCAACCGCTCGGTCTA
		-27	4.8	TGAACCGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP0630	-138	4.1	CGCACCACTTTGTCTA
		-82	4.6	TAGACCGATCGGTTTC
Corynebacterium efficiens YS-314	CE0679	-139	4.6	CGAACCGCTCGGTCTA
		-117	4.9	TAGACCGAGCGGTTCA
Corynebacterium glutamicum ATCC 13032	cg0755	-90	4.5	TATACCACACAGTCTA
		-68	4.7	TAGACCAAGCTGTTCA
Corynebacterium jeikeium K411	jk1694	-171	4.5	TAGACCAAGCGGTATG
		-93	5.2	TAGACAGAGCGGTTTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1568	-300	4.6	CATACCGCTTAGTCTA
		-244	4.4	TAGACAGGGCGGTTTG
		-225	4.8	TAGACCGAGCGGTACA
Corynebacterium urealyticum DSM 7109	cur_0423	-212	4.9	TAGACCAAGTGGTATA
		-145	5.2	TAGACAGAGCGGTTTA

Position: -134 Score: 5.5 Sequence: TAGACAGCTTGGTCTA Locus tag: cur_0694
	cur_0694	-134	5.5	TAGACAGCTTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: hom
Ortholog function: Homoserine dehydrogenase (EC 1.1.1.3)
Corynebacterium aurimucosum ATCC 700975	cauri_1049	-70	4.6	TAGACAGCTCGTTCTG
Corynebacterium efficiens YS-314	CE1289	-110	4.9	TGAACAGCTTGGTCTA
Corynebacterium glutamicum ATCC 13032	cg1337	-113	4.9	TGAACAGCTTGGTCTA
Corynebacterium jeikeium K411	jk1352	-105	5.2	TGGACAGCTTTGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1290	-100	4.5	CATACAGCTTTGTCTG
Corynebacterium urealyticum DSM 7109	cur_0694	-134	5.5	TAGACAGCTTGGTCTA

Position: -110 Score: 5.4 Sequence: TAGACCGCTTGGTCTA Locus tag: cur_0975
	cur_0975	-110	5.4	TAGACCGCTTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metK
Ortholog function: S-adenosylmethionine synthetase (EC 2.5.1.6)
Corynebacterium amycolatum SK46	CORAM0001_0910	-98	4.8	TGAACCGCTTGGTCTA
Corynebacterium aurimucosum ATCC 700975	cauri_1185	-97	5.4	TAGACCGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP1325	-116	5.5	TAGACAGCTTGGTCTA
Corynebacterium efficiens YS-314	CE1723	-73	5.5	TAGACAGCTTGGTCTA
Corynebacterium glutamicum ATCC 13032	cg1806	-74	5.5	TAGACAGCTTGGTCTA
Corynebacterium jeikeium K411	jk1016	-75	5.2	CAGACAGCTTGGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0984	-98	5.5	TAGACAGCTTGGTCTA
Corynebacterium urealyticum DSM 7109	cur_0975	-110	5.4	TAGACCGCTTGGTCTA

Position: -9 Score: 5 Sequence: TAGACAGAGATGTCTA Locus tag: cur_1218
	cur_1218	-9	5	TAGACAGAGATGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metF
Ortholog function: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Corynebacterium aurimucosum ATCC 700975	cauri_0019	-182	4.5	TAGACAGCTTTGTACG
		-70	4.3	TGGACAGCTTGGTACG
Corynebacterium jeikeium K411	jk0737	-30	5.3	TGGACAGCTCTGTCTA
Corynebacterium urealyticum DSM 7109	cur_1218	-9	5	TAGACAGAGATGTCTA

Position: -60 Score: 5.3 Sequence: TAGACAGATCAGTCTA Locus tag: cur_1592
	cur_1592	-60	5.3	TAGACAGATCAGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysK
Ortholog function: Cysteine synthase (EC 2.5.1.47)
Corynebacterium amycolatum SK46	CORAM0001_2226	-103	3.9	TAGACGAACTGGTCTG
Corynebacterium aurimucosum ATCC 700975	cauri_2144	-74	4.8	TATACCACTCAGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP1890	-152	4.5	TAGACCGATCGGTACG
		-130	4.6	AAGACAATTCTGTCTA
Corynebacterium efficiens YS-314	CE2446	-148	4.7	TAGACCGATCCGTCTG
Corynebacterium glutamicum ATCC 13032	cg2833	-150	4.6	TGAACAGAACTGTCTA
Corynebacterium jeikeium K411	jk0394	-35	5.2	TAGACCGATCAGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0419	-152	4.8	CAGACCGATCTGTCTG
Corynebacterium urealyticum DSM 7109	cur_1592	-60	5.3	TAGACAGATCAGTCTA

Position: -219 Score: 4.9 Sequence: TAGACCAGGCGGTCTA Position: -111 Score: 5.1 Sequence: TAGACCGAGCGGTCTG Locus tag: cur_1744
	cur_1744	-219	4.9	TAGACCAGGCGGTCTA
		-111	5.1	TAGACCGAGCGGTCTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysH
Ortholog function: Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
Corynebacterium aurimucosum ATCC 700975	cauri_2335	-115	4.2	TAGTCCGCTCGGTTCA
Corynebacterium efficiens YS-314	CE2642	-281	4.4	CCGACCACTCTGTCTA
		-247	5.1	TAGACCGCTTGGTCTG
		-163	4.4	TAGACCGTCCAGTCTA
		-46	4.6	TAGACAGATCGGTACG
Corynebacterium glutamicum ATCC 13032	cg3116	-286	5.1	TAGACCGCTTGGTCTG
		-201	5.6	TAGACAGATCGGTCTA
		-83	4.5	TAGACAGAGCGGTACG
Corynebacterium jeikeium K411	jk0245	-134	5.3	TGGACAGATTGGTCTA
		-100	4.9	CAGACCGATCGGTCTG
Corynebacterium urealyticum DSM 7109	cur_1744	-219	4.9	TAGACCAGGCGGTCTA
		-111	5.1	TAGACCGAGCGGTCTG

Position: -181 Score: 5.2 Sequence: TAGACAGCATTGTCTA Position: -97 Score: 4.9 Sequence: TAGACCGCACGGTCTG Locus tag: cur_1757
	cur_1757	-181	5.2	TAGACAGCATTGTCTA
		-97	4.9	TAGACCGCACGGTCTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysI
Ortholog function: Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1)
Corynebacterium amycolatum SK46	CORAM0001_1359	-113	4.7	CAGACTGGTCGGTCTA
		-77	5.1	TAGACCAAACGGTCTA
Corynebacterium aurimucosum ATCC 700975	cauri_0665	-65	4.4	AAGACTGCTTTGTCTG
Corynebacterium efficiens YS-314	CE2644	-281	4.4	CCGACCACTCTGTCTA
		-247	5.1	TAGACCGCTTGGTCTG
		-163	4.4	TAGACCGTCCAGTCTA
		-46	4.6	TAGACAGATCGGTACG
Corynebacterium glutamicum ATCC 13032	cg3118	-286	5.1	TAGACCGCTTGGTCTG
		-201	5.6	TAGACAGATCGGTCTA
		-83	4.5	TAGACAGAGCGGTACG
Corynebacterium jeikeium K411	jk0243	-114	5.4	TAGACAACTCTGTCTA
		-34	5	CAGACAGATCAGTCTA
Corynebacterium urealyticum DSM 7109	cur_1757	-181	5.2	TAGACAGCATTGTCTA
		-97	4.9	TAGACCGCACGGTCTG

Position: -124 Score: 5 Sequence: TAGACAATGCTGTCTA Locus tag: cur_1758
	cur_1758	-124	5	TAGACAATGCTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysJ
Ortholog function: Ferredoxin--NADP reductase (EC 1.18.1.2)
Corynebacterium amycolatum SK46	CORAM0001_1361	-98	4.9	TAGACCAGTTTGTCTA
		-63	5.4	TAGACCGATTGGTCTA
Corynebacterium jeikeium K411	jk0242	-297	4.9	TAGACTGATCTGTCTG
		-217	5.4	TAGACAGAGTTGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1688	-198	5.1	TAGACAGAGTGGTATA
Corynebacterium urealyticum DSM 7109	cur_1758	-208	4.9	CAGACCGTGCGGTCTA
		-124	5	TAGACAATGCTGTCTA

Position: -256 Score: 5 Sequence: CAGACCAAGCTGTCTA Locus tag: cur_1766
	cur_1766	-256	5	CAGACCAAGCTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE
Ortholog function: 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (EC 2.1.1.14)
Corynebacterium efficiens YS-314	CE1209	-290	4.3	CAGACCATGCTGTCTG
Corynebacterium glutamicum ATCC 13032	cg1290	-272	4.9	CAGACCGAGCAGTCTA
Corynebacterium jeikeium K411	jk0234	-205	4.8	CAGACTAAGCTGTCTA
Corynebacterium urealyticum DSM 7109	cur_1766	-256	5	CAGACCAAGCTGTCTA

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of McbR regulog to Corynebacterium urealyticum DSM 7109

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --