Propagation of McbR regulog to Corynebacterium amycolatum SK46
| Source regulog: | McbR - Corynebacteriaceae |
| Regulator type: | Transcription factor |
| Regulator family: | TetR |
| Regulation mode: | repressor |
| Biological process: | Methionine biosynthesis |
| Effector: | S-adenosylmethionine; S-adenosylhomocysteine |
| Phylum: | Actinobacteria |
| Propagated regulon: | |
| Target genome | Corynebacterium amycolatum SK46 |
| Orthologous TF(s) | CORAM0001_2083 |
| Regulated genes | 13 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -73
Score: 5 Sequence: TAGACAGCTTGGTTCA
Locus tag: CORAM0001_0291
|
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| CORAM0001_0291 | -73 | 5 | TAGACAGCTTGGTTCA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metY | ||||
| Ortholog function: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_0291 | -73 | 5 | TAGACAGCTTGGTTCA |
| Corynebacterium aurimucosum ATCC 700975 | cauri_0513 | -92 | 4.2 | CCAACCGCTCGGTCTA |
| -27 | 4.8 | TGAACCGCTTGGTCTA | ||
| Corynebacterium diphtheriae NCTC 13129 | DIP0630 | -138 | 4.1 | CGCACCACTTTGTCTA |
| -82 | 4.6 | TAGACCGATCGGTTTC | ||
| Corynebacterium efficiens YS-314 | CE0679 | -139 | 4.6 | CGAACCGCTCGGTCTA |
| -117 | 4.9 | TAGACCGAGCGGTTCA | ||
| Corynebacterium glutamicum ATCC 13032 | cg0755 | -90 | 4.5 | TATACCACACAGTCTA |
| -68 | 4.7 | TAGACCAAGCTGTTCA | ||
| Corynebacterium jeikeium K411 | jk1694 | -171 | 4.5 | TAGACCAAGCGGTATG |
| -93 | 5.2 | TAGACAGAGCGGTTTA | ||
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_1568 | -300 | 4.6 | CATACCGCTTAGTCTA |
| -244 | 4.4 | TAGACAGGGCGGTTTG | ||
| -225 | 4.8 | TAGACCGAGCGGTACA | ||
| Corynebacterium urealyticum DSM 7109 | cur_0423 | -212 | 4.9 | TAGACCAAGTGGTATA |
| -145 | 5.2 | TAGACAGAGCGGTTTA | ||
|
Position: -22
Score: 4.3 Sequence: CGGACTAAGTAGTCTA
Locus tag: CORAM0001_0290
|
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| CORAM0001_0290 | -22 | 4.3 | CGGACTAAGTAGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metX | ||||
| Ortholog function: Homoserine O-acetyltransferase (EC 2.3.1.31) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_0290 | -22 | 4.3 | CGGACTAAGTAGTCTA |
| Corynebacterium aurimucosum ATCC 700975 | cauri_0512 | -92 | 4.2 | CCAACCGCTCGGTCTA |
| -27 | 4.8 | TGAACCGCTTGGTCTA | ||
| Corynebacterium diphtheriae NCTC 13129 | DIP0623 | -60 | 5.2 | TAGACAGAGCTGTCCA |
| Corynebacterium efficiens YS-314 | CE0678 | -139 | 4.6 | CGAACCGCTCGGTCTA |
| -117 | 4.9 | TAGACCGAGCGGTTCA | ||
| Corynebacterium glutamicum ATCC 13032 | cg0754 | -69 | 5.2 | TAGACAGAGCTGTCCA |
| Corynebacterium jeikeium K411 | jk1695 | -171 | 4.5 | TAGACCAAGCGGTATG |
| -93 | 5.2 | TAGACAGAGCGGTTTA | ||
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_1569 | -300 | 4.6 | CATACCGCTTAGTCTA |
| -244 | 4.4 | TAGACAGGGCGGTTTG | ||
| -225 | 4.8 | TAGACCGAGCGGTACA | ||
| Corynebacterium urealyticum DSM 7109 | cur_0422 | -212 | 4.9 | TAGACCAAGTGGTATA |
| -145 | 5.2 | TAGACAGAGCGGTTTA | ||
|
Position: -70
Score: 5 Sequence: AAGACAGCTTGGTCTA
Locus tag: CORAM0001_0284
|
||||
| CORAM0001_0284 | -70 | 5 | AAGACAGCTTGGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metQ | ||||
| Ortholog function: Methionine ABC transporter substrate-binding protein | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_0284 | -70 | 5 | AAGACAGCTTGGTCTA |
| Corynebacterium diphtheriae NCTC 13129 | DIP0611 | -166 | 4.7 | TAGACAAAGCTGTACA |
| Corynebacterium efficiens YS-314 | CE0631 | -94 | 4.7 | TAGACCGAGCTGTACA |
| Corynebacterium glutamicum ATCC 13032 | cg0737 | -109 | 4.6 | TAGACCAAGCTGTACA |
|
Position: -113
Score: 4.7 Sequence: CAGACTGGTCGGTCTA
Position: -77
Score: 5.1 Sequence: TAGACCAAACGGTCTA
Locus tag: CORAM0001_1359
|
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| CORAM0001_1359 | -113 | 4.7 | CAGACTGGTCGGTCTA | |
| -77 | 5.1 | TAGACCAAACGGTCTA | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysI | ||||
| Ortholog function: Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_1359 | -113 | 4.7 | CAGACTGGTCGGTCTA |
| -77 | 5.1 | TAGACCAAACGGTCTA | ||
| Corynebacterium aurimucosum ATCC 700975 | cauri_0665 | -65 | 4.4 | AAGACTGCTTTGTCTG |
| Corynebacterium efficiens YS-314 | CE2644 | -281 | 4.4 | CCGACCACTCTGTCTA |
| -247 | 5.1 | TAGACCGCTTGGTCTG | ||
| -163 | 4.4 | TAGACCGTCCAGTCTA | ||
| -46 | 4.6 | TAGACAGATCGGTACG | ||
| Corynebacterium glutamicum ATCC 13032 | cg3118 | -286 | 5.1 | TAGACCGCTTGGTCTG |
| -201 | 5.6 | TAGACAGATCGGTCTA | ||
| -83 | 4.5 | TAGACAGAGCGGTACG | ||
| Corynebacterium jeikeium K411 | jk0243 | -114 | 5.4 | TAGACAACTCTGTCTA |
| -34 | 5 | CAGACAGATCAGTCTA | ||
| Corynebacterium urealyticum DSM 7109 | cur_1757 | -181 | 5.2 | TAGACAGCATTGTCTA |
| -97 | 4.9 | TAGACCGCACGGTCTG | ||
|
Position: -205
Score: 5.4 Sequence: TAGACCAATCGGTCTA
Position: -170
Score: 4.8 Sequence: TAGACAAACTGGTCTA
Locus tag: CORAM0001_1360
|
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| CORAM0001_1360 | -205 | 5.4 | TAGACCAATCGGTCTA | |
| -170 | 4.8 | TAGACAAACTGGTCTA | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysZ | ||||
| Ortholog function: Sulfate transporter, CysZ-type | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_1360 | -205 | 5.4 | TAGACCAATCGGTCTA |
| -170 | 4.8 | TAGACAAACTGGTCTA | ||
| Corynebacterium efficiens YS-314 | CE2638 | -281 | 4.4 | CCGACCACTCTGTCTA |
| -247 | 5.1 | TAGACCGCTTGGTCTG | ||
| -163 | 4.4 | TAGACCGTCCAGTCTA | ||
| -46 | 4.6 | TAGACAGATCGGTACG | ||
| Corynebacterium glutamicum ATCC 13032 | cg3112 | -286 | 5.1 | TAGACCGCTTGGTCTG |
| -201 | 5.6 | TAGACAGATCGGTCTA | ||
| -83 | 4.5 | TAGACAGAGCGGTACG | ||
| Corynebacterium jeikeium K411 | jk0249 | -23 | 4.2 | TAGACAGCAAGGACTA |
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_1695 | -61 | 5.5 | TAGACCGCTCGGTCTA |
| Corynebacterium urealyticum DSM 7109 | cur_1740 | -219 | 4.9 | TAGACCAGGCGGTCTA |
| -111 | 5.1 | TAGACCGAGCGGTCTG | ||
|
Position: -63
Score: 5.4 Sequence: TAGACCGATTGGTCTA
Locus tag: CORAM0001_1361
|
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| CORAM0001_1361 | -63 | 5.4 | TAGACCGATTGGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysJ | ||||
| Ortholog function: Ferredoxin--NADP reductase (EC 1.18.1.2) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_1361 | -98 | 4.9 | TAGACCAGTTTGTCTA |
| -63 | 5.4 | TAGACCGATTGGTCTA | ||
| Corynebacterium jeikeium K411 | jk0242 | -297 | 4.9 | TAGACTGATCTGTCTG |
| -217 | 5.4 | TAGACAGAGTTGTCTA | ||
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_1688 | -198 | 5.1 | TAGACAGAGTGGTATA |
| Corynebacterium urealyticum DSM 7109 | cur_1758 | -208 | 4.9 | CAGACCGTGCGGTCTA |
| -124 | 5 | TAGACAATGCTGTCTA | ||
|
Position: -65
Score: 4.6 Sequence: TAGACAGGTCTGTTCA
Locus tag: CORAM0001_2013
|
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| CORAM0001_2013 | -65 | 4.6 | TAGACAGGTCTGTTCA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: CE2728 | ||||
| Ortholog function: Predicted permease protein | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_2013 | -163 | 4 | TATACGGTTCGGTCTG |
| -65 | 4.6 | TAGACAGGTCTGTTCA | ||
| Corynebacterium efficiens YS-314 | CE2728 | -99 | 4.9 | TAGACCTCTCTGTCTA |
| Corynebacterium jeikeium K411 | jk0156 | -41 | 4.7 | CAGACAGATCGGTTCA |
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_0159 | -153 | 5.6 | TAGACAGATCGGTCTA |
| Corynebacterium urealyticum DSM 7109 | cur_0176 | -183 | 4.8 | TAGACCGCATGGTCTG |
| -105 | 4.6 | TAGACAGTTCGGTATG | ||
| -39 | 5 | TAGACAGATCGGTTCA | ||
|
Position: -137
Score: 5.2 Sequence: TAGACCACGTGGTCTA
Locus tag: CORAM0001_0385
|
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| CORAM0001_0385 | -137 | 5.2 | TAGACCACGTGGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: ssuR | ||||
| Ortholog function: Sulphonate sulphur utilization transcriptional regulator SsuR, ROK family | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_0385 | -137 | 5.2 | TAGACCACGTGGTCTA |
| -49 | 4.8 | TAGACAACTCGGTACA | ||
| -28 | 4.9 | TAGACAGTATTGTCTA | ||
| Corynebacterium glutamicum ATCC 13032 | cg0012 | -85 | 5.1 | TAGACTGAACGGTCTA |
| -20 | 4.8 | TAGACCATACGGTCTA | ||
|
Position: -25
Score: 5.2 Sequence: TAGACCACGTGGTCTA
Locus tag: CORAM0001_0384
|
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| CORAM0001_0384 | -25 | 5.2 | TAGACCACGTGGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: ssuD | ||||
| Ortholog function: Alkanesulfonate monooxygenase | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_0384 | -134 | 4.8 | TAGACAATACTGTCTA |
| -113 | 4.8 | TGTACCGAGTTGTCTA | ||
| -25 | 5.2 | TAGACCACGTGGTCTA | ||
| Corynebacterium glutamicum ATCC 13032 | cg1376 | -182 | 4.6 | TAGACCGCTTAGTCTT |
| -117 | 5 | TAGACATCTCGGTCTA | ||
| -30 | 4.4 | TAGACGAAGCGGTCTG | ||
| Corynebacterium glutamicum ATCC 13032 | cg1156 | -24 | 5.1 | TAGACCGTGTGGTCTA |
|
Position: -98
Score: 4.8 Sequence: TGAACCGCTTGGTCTA
Locus tag: CORAM0001_0910
|
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| CORAM0001_0910 | -98 | 4.8 | TGAACCGCTTGGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metK | ||||
| Ortholog function: S-adenosylmethionine synthetase (EC 2.5.1.6) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_0910 | -98 | 4.8 | TGAACCGCTTGGTCTA |
| Corynebacterium aurimucosum ATCC 700975 | cauri_1185 | -97 | 5.4 | TAGACCGCTTGGTCTA |
| Corynebacterium diphtheriae NCTC 13129 | DIP1325 | -116 | 5.5 | TAGACAGCTTGGTCTA |
| Corynebacterium efficiens YS-314 | CE1723 | -73 | 5.5 | TAGACAGCTTGGTCTA |
| Corynebacterium glutamicum ATCC 13032 | cg1806 | -74 | 5.5 | TAGACAGCTTGGTCTA |
| Corynebacterium jeikeium K411 | jk1016 | -75 | 5.2 | CAGACAGCTTGGTCTA |
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_0984 | -98 | 5.5 | TAGACAGCTTGGTCTA |
| Corynebacterium urealyticum DSM 7109 | cur_0975 | -110 | 5.4 | TAGACCGCTTGGTCTA |
|
Position: -19
Score: 4.8 Sequence: TGGACTAAGCTGTCTA
Locus tag: CORAM0001_0958
|
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| CORAM0001_0958 | -19 | 4.8 | TGGACTAAGCTGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cg1739 | ||||
| Ortholog function: GMP synthase-Glutamine amidotransferase domain (EC 6.3.5.2) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_0958 | -19 | 4.8 | TGGACTAAGCTGTCTA |
| Corynebacterium amycolatum SK46 | CORAM0001_0957 | -19 | 4.8 | TGGACTAAGCTGTCTA |
| Corynebacterium glutamicum ATCC 13032 | cg1739 | -13 | 4.4 | TAGACTAAGCGGTATG |
| Corynebacterium jeikeium K411 | jk0976 | -30 | 4.9 | TAGACCAAGCGGTCTG |
|
Position: -19
Score: 4.6 Sequence: TAGACTAAGGTGTCTA
Locus tag: CORAM0001_0986
|
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| CORAM0001_0986 | -19 | 4.6 | TAGACTAAGGTGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metH | ||||
| Ortholog function: 5-methyltetrahydrofolate-homocysteine methyltransferase (EC 2.1.1.13) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_0986 | -19 | 4.6 | TAGACTAAGGTGTCTA |
| Corynebacterium diphtheriae NCTC 13129 | DIP1259 | -17 | 4.5 | CATACTAAGCTGTCTA |
| Corynebacterium efficiens YS-314 | CE1637 | -20 | 4.2 | CGTACTAAGCTGTCTA |
| Corynebacterium glutamicum ATCC 13032 | cg1701 | -95 | 4.2 | CGTACTAAGCTGTCTA |
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_0919 | 20 | 5.1 | TAGACTAAGCTGTCTA |
|
Position: -103
Score: 3.9 Sequence: TAGACGAACTGGTCTG
Locus tag: CORAM0001_2226
|
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| CORAM0001_2226 | -103 | 3.9 | TAGACGAACTGGTCTG | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysK | ||||
| Ortholog function: Cysteine synthase (EC 2.5.1.47) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_2226 | -103 | 3.9 | TAGACGAACTGGTCTG |
| Corynebacterium aurimucosum ATCC 700975 | cauri_2144 | -74 | 4.8 | TATACCACTCAGTCTA |
| Corynebacterium diphtheriae NCTC 13129 | DIP1890 | -152 | 4.5 | TAGACCGATCGGTACG |
| -130 | 4.6 | AAGACAATTCTGTCTA | ||
| Corynebacterium efficiens YS-314 | CE2446 | -148 | 4.7 | TAGACCGATCCGTCTG |
| Corynebacterium glutamicum ATCC 13032 | cg2833 | -150 | 4.6 | TGAACAGAACTGTCTA |
| Corynebacterium jeikeium K411 | jk0394 | -35 | 5.2 | TAGACCGATCAGTCTA |
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_0419 | -152 | 4.8 | CAGACCGATCTGTCTG |
| Corynebacterium urealyticum DSM 7109 | cur_1592 | -60 | 5.3 | TAGACAGATCAGTCTA |