Propagation of McbR regulog to Corynebacterium amycolatum SK46

Reference regulog properties
Source regulog:	McbR - Corynebacteriaceae
Regulator type:	Transcription factor
Regulator family:	TetR
Regulation mode:	repressor
Biological process:	Methionine biosynthesis
Effector:	S-adenosylmethionine; S-adenosylhomocysteine
Phylum:	Actinobacteria
Propagated regulon:
Target genome	Corynebacterium amycolatum SK46
Orthologous TF(s)	CORAM0001_2083
Regulated genes	13

Built upon 162 sites [see more]

Predicted regulatory interactions in *Corynebacterium amycolatum SK46*
	Locus tag	Position	Score	Sequence
Position: -73 Score: 5 Sequence: TAGACAGCTTGGTTCA Locus tag: CORAM0001_0291
	CORAM0001_0291	-73	5	TAGACAGCTTGGTTCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metY
Ortholog function: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Corynebacterium amycolatum SK46	CORAM0001_0291	-73	5	TAGACAGCTTGGTTCA
Corynebacterium aurimucosum ATCC 700975	cauri_0513	-92	4.2	CCAACCGCTCGGTCTA
		-27	4.8	TGAACCGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP0630	-138	4.1	CGCACCACTTTGTCTA
		-82	4.6	TAGACCGATCGGTTTC
Corynebacterium efficiens YS-314	CE0679	-139	4.6	CGAACCGCTCGGTCTA
		-117	4.9	TAGACCGAGCGGTTCA
Corynebacterium glutamicum ATCC 13032	cg0755	-90	4.5	TATACCACACAGTCTA
		-68	4.7	TAGACCAAGCTGTTCA
Corynebacterium jeikeium K411	jk1694	-171	4.5	TAGACCAAGCGGTATG
		-93	5.2	TAGACAGAGCGGTTTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1568	-300	4.6	CATACCGCTTAGTCTA
		-244	4.4	TAGACAGGGCGGTTTG
		-225	4.8	TAGACCGAGCGGTACA
Corynebacterium urealyticum DSM 7109	cur_0423	-212	4.9	TAGACCAAGTGGTATA
		-145	5.2	TAGACAGAGCGGTTTA

Position: -22 Score: 4.3 Sequence: CGGACTAAGTAGTCTA Locus tag: CORAM0001_0290
	CORAM0001_0290	-22	4.3	CGGACTAAGTAGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metX
Ortholog function: Homoserine O-acetyltransferase (EC 2.3.1.31)
Corynebacterium amycolatum SK46	CORAM0001_0290	-22	4.3	CGGACTAAGTAGTCTA
Corynebacterium aurimucosum ATCC 700975	cauri_0512	-92	4.2	CCAACCGCTCGGTCTA
		-27	4.8	TGAACCGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP0623	-60	5.2	TAGACAGAGCTGTCCA
Corynebacterium efficiens YS-314	CE0678	-139	4.6	CGAACCGCTCGGTCTA
		-117	4.9	TAGACCGAGCGGTTCA
Corynebacterium glutamicum ATCC 13032	cg0754	-69	5.2	TAGACAGAGCTGTCCA
Corynebacterium jeikeium K411	jk1695	-171	4.5	TAGACCAAGCGGTATG
		-93	5.2	TAGACAGAGCGGTTTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1569	-300	4.6	CATACCGCTTAGTCTA
		-244	4.4	TAGACAGGGCGGTTTG
		-225	4.8	TAGACCGAGCGGTACA
Corynebacterium urealyticum DSM 7109	cur_0422	-212	4.9	TAGACCAAGTGGTATA
		-145	5.2	TAGACAGAGCGGTTTA

Position: -70 Score: 5 Sequence: AAGACAGCTTGGTCTA Locus tag: CORAM0001_0284
	CORAM0001_0284	-70	5	AAGACAGCTTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metQ
Ortholog function: Methionine ABC transporter substrate-binding protein
Corynebacterium amycolatum SK46	CORAM0001_0284	-70	5	AAGACAGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP0611	-166	4.7	TAGACAAAGCTGTACA
Corynebacterium efficiens YS-314	CE0631	-94	4.7	TAGACCGAGCTGTACA
Corynebacterium glutamicum ATCC 13032	cg0737	-109	4.6	TAGACCAAGCTGTACA

Position: -113 Score: 4.7 Sequence: CAGACTGGTCGGTCTA Position: -77 Score: 5.1 Sequence: TAGACCAAACGGTCTA Locus tag: CORAM0001_1359
	CORAM0001_1359	-113	4.7	CAGACTGGTCGGTCTA
		-77	5.1	TAGACCAAACGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysI
Ortholog function: Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1)
Corynebacterium amycolatum SK46	CORAM0001_1359	-113	4.7	CAGACTGGTCGGTCTA
		-77	5.1	TAGACCAAACGGTCTA
Corynebacterium aurimucosum ATCC 700975	cauri_0665	-65	4.4	AAGACTGCTTTGTCTG
Corynebacterium efficiens YS-314	CE2644	-281	4.4	CCGACCACTCTGTCTA
		-247	5.1	TAGACCGCTTGGTCTG
		-163	4.4	TAGACCGTCCAGTCTA
		-46	4.6	TAGACAGATCGGTACG
Corynebacterium glutamicum ATCC 13032	cg3118	-286	5.1	TAGACCGCTTGGTCTG
		-201	5.6	TAGACAGATCGGTCTA
		-83	4.5	TAGACAGAGCGGTACG
Corynebacterium jeikeium K411	jk0243	-114	5.4	TAGACAACTCTGTCTA
		-34	5	CAGACAGATCAGTCTA
Corynebacterium urealyticum DSM 7109	cur_1757	-181	5.2	TAGACAGCATTGTCTA
		-97	4.9	TAGACCGCACGGTCTG

Position: -205 Score: 5.4 Sequence: TAGACCAATCGGTCTA Position: -170 Score: 4.8 Sequence: TAGACAAACTGGTCTA Locus tag: CORAM0001_1360
	CORAM0001_1360	-205	5.4	TAGACCAATCGGTCTA
		-170	4.8	TAGACAAACTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysZ
Ortholog function: Sulfate transporter, CysZ-type
Corynebacterium amycolatum SK46	CORAM0001_1360	-205	5.4	TAGACCAATCGGTCTA
		-170	4.8	TAGACAAACTGGTCTA
Corynebacterium efficiens YS-314	CE2638	-281	4.4	CCGACCACTCTGTCTA
		-247	5.1	TAGACCGCTTGGTCTG
		-163	4.4	TAGACCGTCCAGTCTA
		-46	4.6	TAGACAGATCGGTACG
Corynebacterium glutamicum ATCC 13032	cg3112	-286	5.1	TAGACCGCTTGGTCTG
		-201	5.6	TAGACAGATCGGTCTA
		-83	4.5	TAGACAGAGCGGTACG
Corynebacterium jeikeium K411	jk0249	-23	4.2	TAGACAGCAAGGACTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1695	-61	5.5	TAGACCGCTCGGTCTA
Corynebacterium urealyticum DSM 7109	cur_1740	-219	4.9	TAGACCAGGCGGTCTA
		-111	5.1	TAGACCGAGCGGTCTG

Position: -63 Score: 5.4 Sequence: TAGACCGATTGGTCTA Locus tag: CORAM0001_1361
	CORAM0001_1361	-63	5.4	TAGACCGATTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysJ
Ortholog function: Ferredoxin--NADP reductase (EC 1.18.1.2)
Corynebacterium amycolatum SK46	CORAM0001_1361	-98	4.9	TAGACCAGTTTGTCTA
		-63	5.4	TAGACCGATTGGTCTA
Corynebacterium jeikeium K411	jk0242	-297	4.9	TAGACTGATCTGTCTG
		-217	5.4	TAGACAGAGTTGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1688	-198	5.1	TAGACAGAGTGGTATA
Corynebacterium urealyticum DSM 7109	cur_1758	-208	4.9	CAGACCGTGCGGTCTA
		-124	5	TAGACAATGCTGTCTA

Position: -65 Score: 4.6 Sequence: TAGACAGGTCTGTTCA Locus tag: CORAM0001_2013
	CORAM0001_2013	-65	4.6	TAGACAGGTCTGTTCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: CE2728
Ortholog function: Predicted permease protein
Corynebacterium amycolatum SK46	CORAM0001_2013	-163	4	TATACGGTTCGGTCTG
		-65	4.6	TAGACAGGTCTGTTCA
Corynebacterium efficiens YS-314	CE2728	-99	4.9	TAGACCTCTCTGTCTA
Corynebacterium jeikeium K411	jk0156	-41	4.7	CAGACAGATCGGTTCA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0159	-153	5.6	TAGACAGATCGGTCTA
Corynebacterium urealyticum DSM 7109	cur_0176	-183	4.8	TAGACCGCATGGTCTG
		-105	4.6	TAGACAGTTCGGTATG
		-39	5	TAGACAGATCGGTTCA

Position: -137 Score: 5.2 Sequence: TAGACCACGTGGTCTA Locus tag: CORAM0001_0385
	CORAM0001_0385	-137	5.2	TAGACCACGTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ssuR
Ortholog function: Sulphonate sulphur utilization transcriptional regulator SsuR, ROK family
Corynebacterium amycolatum SK46	CORAM0001_0385	-137	5.2	TAGACCACGTGGTCTA
		-49	4.8	TAGACAACTCGGTACA
		-28	4.9	TAGACAGTATTGTCTA
Corynebacterium glutamicum ATCC 13032	cg0012	-85	5.1	TAGACTGAACGGTCTA
		-20	4.8	TAGACCATACGGTCTA

Position: -25 Score: 5.2 Sequence: TAGACCACGTGGTCTA Locus tag: CORAM0001_0384
	CORAM0001_0384	-25	5.2	TAGACCACGTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ssuD
Ortholog function: Alkanesulfonate monooxygenase
Corynebacterium amycolatum SK46	CORAM0001_0384	-134	4.8	TAGACAATACTGTCTA
		-113	4.8	TGTACCGAGTTGTCTA
		-25	5.2	TAGACCACGTGGTCTA
Corynebacterium glutamicum ATCC 13032	cg1376	-182	4.6	TAGACCGCTTAGTCTT
		-117	5	TAGACATCTCGGTCTA
		-30	4.4	TAGACGAAGCGGTCTG
Corynebacterium glutamicum ATCC 13032	cg1156	-24	5.1	TAGACCGTGTGGTCTA

Position: -98 Score: 4.8 Sequence: TGAACCGCTTGGTCTA Locus tag: CORAM0001_0910
	CORAM0001_0910	-98	4.8	TGAACCGCTTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metK
Ortholog function: S-adenosylmethionine synthetase (EC 2.5.1.6)
Corynebacterium amycolatum SK46	CORAM0001_0910	-98	4.8	TGAACCGCTTGGTCTA
Corynebacterium aurimucosum ATCC 700975	cauri_1185	-97	5.4	TAGACCGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP1325	-116	5.5	TAGACAGCTTGGTCTA
Corynebacterium efficiens YS-314	CE1723	-73	5.5	TAGACAGCTTGGTCTA
Corynebacterium glutamicum ATCC 13032	cg1806	-74	5.5	TAGACAGCTTGGTCTA
Corynebacterium jeikeium K411	jk1016	-75	5.2	CAGACAGCTTGGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0984	-98	5.5	TAGACAGCTTGGTCTA
Corynebacterium urealyticum DSM 7109	cur_0975	-110	5.4	TAGACCGCTTGGTCTA

Position: -19 Score: 4.8 Sequence: TGGACTAAGCTGTCTA Locus tag: CORAM0001_0958
	CORAM0001_0958	-19	4.8	TGGACTAAGCTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cg1739
Ortholog function: GMP synthase-Glutamine amidotransferase domain (EC 6.3.5.2)
Corynebacterium amycolatum SK46	CORAM0001_0958	-19	4.8	TGGACTAAGCTGTCTA
Corynebacterium amycolatum SK46	CORAM0001_0957	-19	4.8	TGGACTAAGCTGTCTA
Corynebacterium glutamicum ATCC 13032	cg1739	-13	4.4	TAGACTAAGCGGTATG
Corynebacterium jeikeium K411	jk0976	-30	4.9	TAGACCAAGCGGTCTG

Position: -19 Score: 4.6 Sequence: TAGACTAAGGTGTCTA Locus tag: CORAM0001_0986
	CORAM0001_0986	-19	4.6	TAGACTAAGGTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metH
Ortholog function: 5-methyltetrahydrofolate-homocysteine methyltransferase (EC 2.1.1.13)
Corynebacterium amycolatum SK46	CORAM0001_0986	-19	4.6	TAGACTAAGGTGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP1259	-17	4.5	CATACTAAGCTGTCTA
Corynebacterium efficiens YS-314	CE1637	-20	4.2	CGTACTAAGCTGTCTA
Corynebacterium glutamicum ATCC 13032	cg1701	-95	4.2	CGTACTAAGCTGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0919	20	5.1	TAGACTAAGCTGTCTA

Position: -103 Score: 3.9 Sequence: TAGACGAACTGGTCTG Locus tag: CORAM0001_2226
	CORAM0001_2226	-103	3.9	TAGACGAACTGGTCTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysK
Ortholog function: Cysteine synthase (EC 2.5.1.47)
Corynebacterium amycolatum SK46	CORAM0001_2226	-103	3.9	TAGACGAACTGGTCTG
Corynebacterium aurimucosum ATCC 700975	cauri_2144	-74	4.8	TATACCACTCAGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP1890	-152	4.5	TAGACCGATCGGTACG
		-130	4.6	AAGACAATTCTGTCTA
Corynebacterium efficiens YS-314	CE2446	-148	4.7	TAGACCGATCCGTCTG
Corynebacterium glutamicum ATCC 13032	cg2833	-150	4.6	TGAACAGAACTGTCTA
Corynebacterium jeikeium K411	jk0394	-35	5.2	TAGACCGATCAGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0419	-152	4.8	CAGACCGATCTGTCTG
Corynebacterium urealyticum DSM 7109	cur_1592	-60	5.3	TAGACAGATCAGTCTA

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of McbR regulog to Corynebacterium amycolatum SK46

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --