Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of McbR regulog to Corynebacterium kroppenstedtii DSM 44385

Reference regulog properties
Source regulog: McbR - Corynebacteriaceae
Regulator type: Transcription factor
Regulator family: TetR
Regulation mode: repressor
Biological process: Methionine biosynthesis
Effector: S-adenosylmethionine; S-adenosylhomocysteine
Phylum: Actinobacteria
Propagated regulon:
Target genome Corynebacterium kroppenstedtii DSM 44385
Orthologous TF(s) ckrop_0099
Regulated genes 10
Built upon 162 sites [see more]
Predicted regulatory interactions in Corynebacterium kroppenstedtii DSM 44385
Locus tag Position Score Sequence
Position: -153
Score: 5.6
Sequence: TAGACAGATCGGTCTA
Locus tag: ckrop_0159
ckrop_0159 -153 5.6 TAGACAGATCGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: CE2728
Ortholog function: Predicted permease protein
Corynebacterium amycolatum SK46 CORAM0001_2013 -163 4 TATACGGTTCGGTCTG
-65 4.6 TAGACAGGTCTGTTCA
Corynebacterium efficiens YS-314 CE2728 -99 4.9 TAGACCTCTCTGTCTA
Corynebacterium jeikeium K411 jk0156 -41 4.7 CAGACAGATCGGTTCA
Corynebacterium kroppenstedtii DSM 44385 ckrop_0159 -153 5.6 TAGACAGATCGGTCTA
Corynebacterium urealyticum DSM 7109 cur_0176 -183 4.8 TAGACCGCATGGTCTG
-105 4.6 TAGACAGTTCGGTATG
-39 5 TAGACAGATCGGTTCA
Position: -152
Score: 4.8
Sequence: CAGACCGATCTGTCTG
Locus tag: ckrop_0419
ckrop_0419 -152 4.8 CAGACCGATCTGTCTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysK
Ortholog function: Cysteine synthase (EC 2.5.1.47)
Corynebacterium amycolatum SK46 CORAM0001_2226 -103 3.9 TAGACGAACTGGTCTG
Corynebacterium aurimucosum ATCC 700975 cauri_2144 -74 4.8 TATACCACTCAGTCTA
Corynebacterium diphtheriae NCTC 13129 DIP1890 -152 4.5 TAGACCGATCGGTACG
-130 4.6 AAGACAATTCTGTCTA
Corynebacterium efficiens YS-314 CE2446 -148 4.7 TAGACCGATCCGTCTG
Corynebacterium glutamicum ATCC 13032 cg2833 -150 4.6 TGAACAGAACTGTCTA
Corynebacterium jeikeium K411 jk0394 -35 5.2 TAGACCGATCAGTCTA
Corynebacterium kroppenstedtii DSM 44385 ckrop_0419 -152 4.8 CAGACCGATCTGTCTG
Corynebacterium urealyticum DSM 7109 cur_1592 -60 5.3 TAGACAGATCAGTCTA
Position: 20
Score: 5.1
Sequence: TAGACTAAGCTGTCTA
Locus tag: ckrop_0919
ckrop_0919 20 5.1 TAGACTAAGCTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metH
Ortholog function: 5-methyltetrahydrofolate-homocysteine methyltransferase (EC 2.1.1.13)
Corynebacterium amycolatum SK46 CORAM0001_0986 -19 4.6 TAGACTAAGGTGTCTA
Corynebacterium diphtheriae NCTC 13129 DIP1259 -17 4.5 CATACTAAGCTGTCTA
Corynebacterium efficiens YS-314 CE1637 -20 4.2 CGTACTAAGCTGTCTA
Corynebacterium glutamicum ATCC 13032 cg1701 -95 4.2 CGTACTAAGCTGTCTA
Corynebacterium kroppenstedtii DSM 44385 ckrop_0919 20 5.1 TAGACTAAGCTGTCTA
Position: -98
Score: 5.5
Sequence: TAGACAGCTTGGTCTA
Locus tag: ckrop_0984
ckrop_0984 -98 5.5 TAGACAGCTTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metK
Ortholog function: S-adenosylmethionine synthetase (EC 2.5.1.6)
Corynebacterium amycolatum SK46 CORAM0001_0910 -98 4.8 TGAACCGCTTGGTCTA
Corynebacterium aurimucosum ATCC 700975 cauri_1185 -97 5.4 TAGACCGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129 DIP1325 -116 5.5 TAGACAGCTTGGTCTA
Corynebacterium efficiens YS-314 CE1723 -73 5.5 TAGACAGCTTGGTCTA
Corynebacterium glutamicum ATCC 13032 cg1806 -74 5.5 TAGACAGCTTGGTCTA
Corynebacterium jeikeium K411 jk1016 -75 5.2 CAGACAGCTTGGTCTA
Corynebacterium kroppenstedtii DSM 44385 ckrop_0984 -98 5.5 TAGACAGCTTGGTCTA
Corynebacterium urealyticum DSM 7109 cur_0975 -110 5.4 TAGACCGCTTGGTCTA
Position: -100
Score: 4.5
Sequence: CATACAGCTTTGTCTG
Locus tag: ckrop_1290
ckrop_1290 -100 4.5 CATACAGCTTTGTCTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: hom
Ortholog function: Homoserine dehydrogenase (EC 1.1.1.3)
Corynebacterium aurimucosum ATCC 700975 cauri_1049 -70 4.6 TAGACAGCTCGTTCTG
Corynebacterium efficiens YS-314 CE1289 -110 4.9 TGAACAGCTTGGTCTA
Corynebacterium glutamicum ATCC 13032 cg1337 -113 4.9 TGAACAGCTTGGTCTA
Corynebacterium jeikeium K411 jk1352 -105 5.2 TGGACAGCTTTGTCTA
Corynebacterium kroppenstedtii DSM 44385 ckrop_1290 -100 4.5 CATACAGCTTTGTCTG
Corynebacterium urealyticum DSM 7109 cur_0694 -134 5.5 TAGACAGCTTGGTCTA
Position: -300
Score: 4.6
Sequence: CATACCGCTTAGTCTA
Position: -225
Score: 4.8
Sequence: TAGACCGAGCGGTACA
Locus tag: ckrop_1568
ckrop_1568 -300 4.6 CATACCGCTTAGTCTA
-225 4.8 TAGACCGAGCGGTACA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metY
Ortholog function: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Corynebacterium amycolatum SK46 CORAM0001_0291 -73 5 TAGACAGCTTGGTTCA
Corynebacterium aurimucosum ATCC 700975 cauri_0513 -92 4.2 CCAACCGCTCGGTCTA
-27 4.8 TGAACCGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129 DIP0630 -138 4.1 CGCACCACTTTGTCTA
-82 4.6 TAGACCGATCGGTTTC
Corynebacterium efficiens YS-314 CE0679 -139 4.6 CGAACCGCTCGGTCTA
-117 4.9 TAGACCGAGCGGTTCA
Corynebacterium glutamicum ATCC 13032 cg0755 -90 4.5 TATACCACACAGTCTA
-68 4.7 TAGACCAAGCTGTTCA
Corynebacterium jeikeium K411 jk1694 -171 4.5 TAGACCAAGCGGTATG
-93 5.2 TAGACAGAGCGGTTTA
Corynebacterium kroppenstedtii DSM 44385 ckrop_1568 -300 4.6 CATACCGCTTAGTCTA
-244 4.4 TAGACAGGGCGGTTTG
-225 4.8 TAGACCGAGCGGTACA
Corynebacterium urealyticum DSM 7109 cur_0423 -212 4.9 TAGACCAAGTGGTATA
-145 5.2 TAGACAGAGCGGTTTA
Position: -198
Score: 5.1
Sequence: TAGACAGAGTGGTATA
Locus tag: ckrop_1688
ckrop_1688 -198 5.1 TAGACAGAGTGGTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysJ
Ortholog function: Ferredoxin--NADP reductase (EC 1.18.1.2)
Corynebacterium amycolatum SK46 CORAM0001_1361 -98 4.9 TAGACCAGTTTGTCTA
-63 5.4 TAGACCGATTGGTCTA
Corynebacterium jeikeium K411 jk0242 -297 4.9 TAGACTGATCTGTCTG
-217 5.4 TAGACAGAGTTGTCTA
Corynebacterium kroppenstedtii DSM 44385 ckrop_1688 -198 5.1 TAGACAGAGTGGTATA
Corynebacterium urealyticum DSM 7109 cur_1758 -208 4.9 CAGACCGTGCGGTCTA
-124 5 TAGACAATGCTGTCTA
Position: -334
Score: 5.5
Sequence: TAGACAGAGCGGTCTA
Position: -301
Score: 4.5
Sequence: AAAACAACTTGGTCTA
Locus tag: ckrop_1693
ckrop_1693 -334 5.5 TAGACAGAGCGGTCTA
-301 4.5 AAAACAACTTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysI
Ortholog function: Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1)
Corynebacterium amycolatum SK46 CORAM0001_1359 -113 4.7 CAGACTGGTCGGTCTA
-77 5.1 TAGACCAAACGGTCTA
Corynebacterium aurimucosum ATCC 700975 cauri_0665 -65 4.4 AAGACTGCTTTGTCTG
Corynebacterium efficiens YS-314 CE2644 -281 4.4 CCGACCACTCTGTCTA
-247 5.1 TAGACCGCTTGGTCTG
-163 4.4 TAGACCGTCCAGTCTA
-46 4.6 TAGACAGATCGGTACG
Corynebacterium glutamicum ATCC 13032 cg3118 -286 5.1 TAGACCGCTTGGTCTG
-201 5.6 TAGACAGATCGGTCTA
-83 4.5 TAGACAGAGCGGTACG
Corynebacterium jeikeium K411 jk0243 -114 5.4 TAGACAACTCTGTCTA
-34 5 CAGACAGATCAGTCTA
Corynebacterium urealyticum DSM 7109 cur_1757 -181 5.2 TAGACAGCATTGTCTA
-97 4.9 TAGACCGCACGGTCTG
Position: -61
Score: 5.5
Sequence: TAGACCGCTCGGTCTA
Locus tag: ckrop_1695
ckrop_1695 -61 5.5 TAGACCGCTCGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysZ
Ortholog function: Sulfate transporter, CysZ-type
Corynebacterium amycolatum SK46 CORAM0001_1360 -205 5.4 TAGACCAATCGGTCTA
-170 4.8 TAGACAAACTGGTCTA
Corynebacterium efficiens YS-314 CE2638 -281 4.4 CCGACCACTCTGTCTA
-247 5.1 TAGACCGCTTGGTCTG
-163 4.4 TAGACCGTCCAGTCTA
-46 4.6 TAGACAGATCGGTACG
Corynebacterium glutamicum ATCC 13032 cg3112 -286 5.1 TAGACCGCTTGGTCTG
-201 5.6 TAGACAGATCGGTCTA
-83 4.5 TAGACAGAGCGGTACG
Corynebacterium jeikeium K411 jk0249 -23 4.2 TAGACAGCAAGGACTA
Corynebacterium kroppenstedtii DSM 44385 ckrop_1695 -61 5.5 TAGACCGCTCGGTCTA
Corynebacterium urealyticum DSM 7109 cur_1740 -219 4.9 TAGACCAGGCGGTCTA
-111 5.1 TAGACCGAGCGGTCTG
Position: -88
Score: 4.4
Sequence: TAGACAGACCAGTCTG
Locus tag: ckrop_1960
ckrop_1960 -88 4.4 TAGACAGACCAGTCTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: gltT
Ortholog function: Predicted sodium:dicarboxylate symporter
Corynebacterium aurimucosum ATCC 700975 cauri_0959 -72 4.5 TGAACCGATCGGTATA
-29 4.8 TATACAACACTGTCTA
Corynebacterium glutamicum ATCC 13032 cg2810 -175 4.3 TAGACTTATGGGTCTA
-118 5.2 TAGACAGATCTGTTTA
Corynebacterium kroppenstedtii DSM 44385 ckrop_1960 -88 4.4 TAGACAGACCAGTCTG