Propagation of McbR regulog to Corynebacterium jeikeium K411

Reference regulog properties
Source regulog:	McbR - Corynebacteriaceae
Regulator type:	Transcription factor
Regulator family:	TetR
Regulation mode:	repressor
Biological process:	Methionine biosynthesis
Effector:	S-adenosylmethionine; S-adenosylhomocysteine
Phylum:	Actinobacteria
Propagated regulon:
Target genome	Corynebacterium jeikeium K411
Orthologous TF(s)	jk0101
Regulated genes	14

Built upon 162 sites [see more]

Predicted regulatory interactions in *Corynebacterium jeikeium K411*
	Locus tag	Position	Score	Sequence
Position: -108 Score: 5.3 Sequence: TAGACTGCTTGGTCTA Locus tag: jk0055
	jk0055	-108	5.3	TAGACTGCTTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metB
Ortholog function: Cystathionine gamma-synthase (EC 2.5.1.48)
Corynebacterium aurimucosum ATCC 700975	cauri_2045	-28	4.9	TGAACAGCTTGGTCTA
Corynebacterium efficiens YS-314	CE2343	1	5.3	TGGACAGCTTGGTCTA
Corynebacterium glutamicum ATCC 13032	cg2687	-78	5.3	TGGACAGCTTGGTCTA
Corynebacterium jeikeium K411	jk0055	-108	5.3	TAGACTGCTTGGTCTA

Position: -41 Score: 4.7 Sequence: CAGACAGATCGGTTCA Locus tag: jk0156
	jk0156	-41	4.7	CAGACAGATCGGTTCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: CE2728
Ortholog function: Predicted permease protein
Corynebacterium amycolatum SK46	CORAM0001_2013	-163	4	TATACGGTTCGGTCTG
		-65	4.6	TAGACAGGTCTGTTCA
Corynebacterium efficiens YS-314	CE2728	-99	4.9	TAGACCTCTCTGTCTA
Corynebacterium jeikeium K411	jk0156	-41	4.7	CAGACAGATCGGTTCA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0159	-153	5.6	TAGACAGATCGGTCTA
Corynebacterium urealyticum DSM 7109	cur_0176	-183	4.8	TAGACCGCATGGTCTG
		-105	4.6	TAGACAGTTCGGTATG
		-39	5	TAGACAGATCGGTTCA

Position: -205 Score: 4.8 Sequence: CAGACTAAGCTGTCTA Locus tag: jk0234
	jk0234	-205	4.8	CAGACTAAGCTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE
Ortholog function: 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (EC 2.1.1.14)
Corynebacterium efficiens YS-314	CE1209	-290	4.3	CAGACCATGCTGTCTG
Corynebacterium glutamicum ATCC 13032	cg1290	-272	4.9	CAGACCGAGCAGTCTA
Corynebacterium jeikeium K411	jk0234	-205	4.8	CAGACTAAGCTGTCTA
Corynebacterium urealyticum DSM 7109	cur_1766	-256	5	CAGACCAAGCTGTCTA

Position: -297 Score: 4.9 Sequence: TAGACTGATCTGTCTG Position: -217 Score: 5.4 Sequence: TAGACAGAGTTGTCTA Locus tag: jk0242
	jk0242	-297	4.9	TAGACTGATCTGTCTG
		-217	5.4	TAGACAGAGTTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysJ
Ortholog function: Ferredoxin--NADP reductase (EC 1.18.1.2)
Corynebacterium amycolatum SK46	CORAM0001_1361	-98	4.9	TAGACCAGTTTGTCTA
		-63	5.4	TAGACCGATTGGTCTA
Corynebacterium jeikeium K411	jk0242	-297	4.9	TAGACTGATCTGTCTG
		-217	5.4	TAGACAGAGTTGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1688	-198	5.1	TAGACAGAGTGGTATA
Corynebacterium urealyticum DSM 7109	cur_1758	-208	4.9	CAGACCGTGCGGTCTA
		-124	5	TAGACAATGCTGTCTA

Position: -114 Score: 5.4 Sequence: TAGACAACTCTGTCTA Position: -34 Score: 5 Sequence: CAGACAGATCAGTCTA Locus tag: jk0243
	jk0243	-114	5.4	TAGACAACTCTGTCTA
		-34	5	CAGACAGATCAGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysI
Ortholog function: Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1)
Corynebacterium amycolatum SK46	CORAM0001_1359	-113	4.7	CAGACTGGTCGGTCTA
		-77	5.1	TAGACCAAACGGTCTA
Corynebacterium aurimucosum ATCC 700975	cauri_0665	-65	4.4	AAGACTGCTTTGTCTG
Corynebacterium efficiens YS-314	CE2644	-281	4.4	CCGACCACTCTGTCTA
		-247	5.1	TAGACCGCTTGGTCTG
		-163	4.4	TAGACCGTCCAGTCTA
		-46	4.6	TAGACAGATCGGTACG
Corynebacterium glutamicum ATCC 13032	cg3118	-286	5.1	TAGACCGCTTGGTCTG
		-201	5.6	TAGACAGATCGGTCTA
		-83	4.5	TAGACAGAGCGGTACG
Corynebacterium jeikeium K411	jk0243	-114	5.4	TAGACAACTCTGTCTA
		-34	5	CAGACAGATCAGTCTA
Corynebacterium urealyticum DSM 7109	cur_1757	-181	5.2	TAGACAGCATTGTCTA
		-97	4.9	TAGACCGCACGGTCTG

Position: -134 Score: 5.3 Sequence: TGGACAGATTGGTCTA Position: -100 Score: 4.9 Sequence: CAGACCGATCGGTCTG Locus tag: jk0245
	jk0245	-134	5.3	TGGACAGATTGGTCTA
		-100	4.9	CAGACCGATCGGTCTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysH
Ortholog function: Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
Corynebacterium aurimucosum ATCC 700975	cauri_2335	-115	4.2	TAGTCCGCTCGGTTCA
Corynebacterium efficiens YS-314	CE2642	-281	4.4	CCGACCACTCTGTCTA
		-247	5.1	TAGACCGCTTGGTCTG
		-163	4.4	TAGACCGTCCAGTCTA
		-46	4.6	TAGACAGATCGGTACG
Corynebacterium glutamicum ATCC 13032	cg3116	-286	5.1	TAGACCGCTTGGTCTG
		-201	5.6	TAGACAGATCGGTCTA
		-83	4.5	TAGACAGAGCGGTACG
Corynebacterium jeikeium K411	jk0245	-134	5.3	TGGACAGATTGGTCTA
		-100	4.9	CAGACCGATCGGTCTG
Corynebacterium urealyticum DSM 7109	cur_1744	-219	4.9	TAGACCAGGCGGTCTA
		-111	5.1	TAGACCGAGCGGTCTG

Position: -23 Score: 4.2 Sequence: TAGACAGCAAGGACTA Locus tag: jk0249
	jk0249	-23	4.2	TAGACAGCAAGGACTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysZ
Ortholog function: Sulfate transporter, CysZ-type
Corynebacterium amycolatum SK46	CORAM0001_1360	-205	5.4	TAGACCAATCGGTCTA
		-170	4.8	TAGACAAACTGGTCTA
Corynebacterium efficiens YS-314	CE2638	-281	4.4	CCGACCACTCTGTCTA
		-247	5.1	TAGACCGCTTGGTCTG
		-163	4.4	TAGACCGTCCAGTCTA
		-46	4.6	TAGACAGATCGGTACG
Corynebacterium glutamicum ATCC 13032	cg3112	-286	5.1	TAGACCGCTTGGTCTG
		-201	5.6	TAGACAGATCGGTCTA
		-83	4.5	TAGACAGAGCGGTACG
Corynebacterium jeikeium K411	jk0249	-23	4.2	TAGACAGCAAGGACTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1695	-61	5.5	TAGACCGCTCGGTCTA
Corynebacterium urealyticum DSM 7109	cur_1740	-219	4.9	TAGACCAGGCGGTCTA
		-111	5.1	TAGACCGAGCGGTCTG

Position: -49 Score: 3.8 Sequence: TAGACTTCCCGGTATA Position: -35 Score: 5.2 Sequence: TAGACCGATCAGTCTA Locus tag: jk0394
	jk0394	-49	3.8	TAGACTTCCCGGTATA
		-35	5.2	TAGACCGATCAGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysK
Ortholog function: Cysteine synthase (EC 2.5.1.47)
Corynebacterium amycolatum SK46	CORAM0001_2226	-103	3.9	TAGACGAACTGGTCTG
Corynebacterium aurimucosum ATCC 700975	cauri_2144	-74	4.8	TATACCACTCAGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP1890	-152	4.5	TAGACCGATCGGTACG
		-130	4.6	AAGACAATTCTGTCTA
Corynebacterium efficiens YS-314	CE2446	-148	4.7	TAGACCGATCCGTCTG
Corynebacterium glutamicum ATCC 13032	cg2833	-150	4.6	TGAACAGAACTGTCTA
Corynebacterium jeikeium K411	jk0394	-35	5.2	TAGACCGATCAGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0419	-152	4.8	CAGACCGATCTGTCTG
Corynebacterium urealyticum DSM 7109	cur_1592	-60	5.3	TAGACAGATCAGTCTA

Position: -30 Score: 5.3 Sequence: TGGACAGCTCTGTCTA Locus tag: jk0737
	jk0737	-30	5.3	TGGACAGCTCTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metF
Ortholog function: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Corynebacterium aurimucosum ATCC 700975	cauri_0019	-182	4.5	TAGACAGCTTTGTACG
		-70	4.3	TGGACAGCTTGGTACG
Corynebacterium jeikeium K411	jk0737	-30	5.3	TGGACAGCTCTGTCTA
Corynebacterium urealyticum DSM 7109	cur_1218	-9	5	TAGACAGAGATGTCTA

Position: -30 Score: 4.9 Sequence: TAGACCAAGCGGTCTG Locus tag: jk0976
	jk0976	-30	4.9	TAGACCAAGCGGTCTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: cg1739
Ortholog function: GMP synthase-Glutamine amidotransferase domain (EC 6.3.5.2)
Corynebacterium amycolatum SK46	CORAM0001_0958	-19	4.8	TGGACTAAGCTGTCTA
Corynebacterium amycolatum SK46	CORAM0001_0957	-19	4.8	TGGACTAAGCTGTCTA
Corynebacterium glutamicum ATCC 13032	cg1739	-13	4.4	TAGACTAAGCGGTATG
Corynebacterium jeikeium K411	jk0976	-30	4.9	TAGACCAAGCGGTCTG

Position: -75 Score: 5.2 Sequence: CAGACAGCTTGGTCTA Locus tag: jk1016
	jk1016	-75	5.2	CAGACAGCTTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metK
Ortholog function: S-adenosylmethionine synthetase (EC 2.5.1.6)
Corynebacterium amycolatum SK46	CORAM0001_0910	-98	4.8	TGAACCGCTTGGTCTA
Corynebacterium aurimucosum ATCC 700975	cauri_1185	-97	5.4	TAGACCGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP1325	-116	5.5	TAGACAGCTTGGTCTA
Corynebacterium efficiens YS-314	CE1723	-73	5.5	TAGACAGCTTGGTCTA
Corynebacterium glutamicum ATCC 13032	cg1806	-74	5.5	TAGACAGCTTGGTCTA
Corynebacterium jeikeium K411	jk1016	-75	5.2	CAGACAGCTTGGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0984	-98	5.5	TAGACAGCTTGGTCTA
Corynebacterium urealyticum DSM 7109	cur_0975	-110	5.4	TAGACCGCTTGGTCTA

Position: -105 Score: 5.2 Sequence: TGGACAGCTTTGTCTA Locus tag: jk1352
	jk1352	-105	5.2	TGGACAGCTTTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: hom
Ortholog function: Homoserine dehydrogenase (EC 1.1.1.3)
Corynebacterium aurimucosum ATCC 700975	cauri_1049	-70	4.6	TAGACAGCTCGTTCTG
Corynebacterium efficiens YS-314	CE1289	-110	4.9	TGAACAGCTTGGTCTA
Corynebacterium glutamicum ATCC 13032	cg1337	-113	4.9	TGAACAGCTTGGTCTA
Corynebacterium jeikeium K411	jk1352	-105	5.2	TGGACAGCTTTGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1290	-100	4.5	CATACAGCTTTGTCTG
Corynebacterium urealyticum DSM 7109	cur_0694	-134	5.5	TAGACAGCTTGGTCTA

Position: -171 Score: 4.5 Sequence: TAGACCAAGCGGTATG Position: -93 Score: 5.2 Sequence: TAGACAGAGCGGTTTA Locus tag: jk1694
	jk1694	-171	4.5	TAGACCAAGCGGTATG
		-93	5.2	TAGACAGAGCGGTTTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metY
Ortholog function: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Corynebacterium amycolatum SK46	CORAM0001_0291	-73	5	TAGACAGCTTGGTTCA
Corynebacterium aurimucosum ATCC 700975	cauri_0513	-92	4.2	CCAACCGCTCGGTCTA
		-27	4.8	TGAACCGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP0630	-138	4.1	CGCACCACTTTGTCTA
		-82	4.6	TAGACCGATCGGTTTC
Corynebacterium efficiens YS-314	CE0679	-139	4.6	CGAACCGCTCGGTCTA
		-117	4.9	TAGACCGAGCGGTTCA
Corynebacterium glutamicum ATCC 13032	cg0755	-90	4.5	TATACCACACAGTCTA
		-68	4.7	TAGACCAAGCTGTTCA
Corynebacterium jeikeium K411	jk1694	-171	4.5	TAGACCAAGCGGTATG
		-93	5.2	TAGACAGAGCGGTTTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1568	-300	4.6	CATACCGCTTAGTCTA
		-244	4.4	TAGACAGGGCGGTTTG
		-225	4.8	TAGACCGAGCGGTACA
Corynebacterium urealyticum DSM 7109	cur_0423	-212	4.9	TAGACCAAGTGGTATA
		-145	5.2	TAGACAGAGCGGTTTA

Position: -103 Score: 4.5 Sequence: TAGACTAAGTTGTTCA Locus tag: jk1710
	jk1710	-103	4.5	TAGACTAAGTTGTTCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metQ
Ortholog function: Methionine ABC transporter substrate-binding protein
Corynebacterium jeikeium K411	jk1710	-103	4.5	TAGACTAAGTTGTTCA
Corynebacterium urealyticum DSM 7109	cur_0411	-127	4.9	TAGACCAAGTTGTCCA

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of McbR regulog to Corynebacterium jeikeium K411

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --