Propagation of McbR regulog to Corynebacterium jeikeium K411
| Source regulog: | McbR - Corynebacteriaceae |
| Regulator type: | Transcription factor |
| Regulator family: | TetR |
| Regulation mode: | repressor |
| Biological process: | Methionine biosynthesis |
| Effector: | S-adenosylmethionine; S-adenosylhomocysteine |
| Phylum: | Actinobacteria |
| Propagated regulon: | |
| Target genome | Corynebacterium jeikeium K411 |
| Orthologous TF(s) | jk0101 |
| Regulated genes | 14 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -108
Score: 5.3 Sequence: TAGACTGCTTGGTCTA
Locus tag: jk0055
|
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| jk0055 | -108 | 5.3 | TAGACTGCTTGGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metB | ||||
| Ortholog function: Cystathionine gamma-synthase (EC 2.5.1.48) | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_2045 | -28 | 4.9 | TGAACAGCTTGGTCTA |
| Corynebacterium efficiens YS-314 | CE2343 | 1 | 5.3 | TGGACAGCTTGGTCTA |
| Corynebacterium glutamicum ATCC 13032 | cg2687 | -78 | 5.3 | TGGACAGCTTGGTCTA |
| Corynebacterium jeikeium K411 | jk0055 | -108 | 5.3 | TAGACTGCTTGGTCTA |
|
Position: -41
Score: 4.7 Sequence: CAGACAGATCGGTTCA
Locus tag: jk0156
|
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| jk0156 | -41 | 4.7 | CAGACAGATCGGTTCA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: CE2728 | ||||
| Ortholog function: Predicted permease protein | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_2013 | -163 | 4 | TATACGGTTCGGTCTG |
| -65 | 4.6 | TAGACAGGTCTGTTCA | ||
| Corynebacterium efficiens YS-314 | CE2728 | -99 | 4.9 | TAGACCTCTCTGTCTA |
| Corynebacterium jeikeium K411 | jk0156 | -41 | 4.7 | CAGACAGATCGGTTCA |
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_0159 | -153 | 5.6 | TAGACAGATCGGTCTA |
| Corynebacterium urealyticum DSM 7109 | cur_0176 | -183 | 4.8 | TAGACCGCATGGTCTG |
| -105 | 4.6 | TAGACAGTTCGGTATG | ||
| -39 | 5 | TAGACAGATCGGTTCA | ||
|
Position: -205
Score: 4.8 Sequence: CAGACTAAGCTGTCTA
Locus tag: jk0234
|
||||
| jk0234 | -205 | 4.8 | CAGACTAAGCTGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metE | ||||
| Ortholog function: 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (EC 2.1.1.14) | ||||
| Corynebacterium efficiens YS-314 | CE1209 | -290 | 4.3 | CAGACCATGCTGTCTG |
| Corynebacterium glutamicum ATCC 13032 | cg1290 | -272 | 4.9 | CAGACCGAGCAGTCTA |
| Corynebacterium jeikeium K411 | jk0234 | -205 | 4.8 | CAGACTAAGCTGTCTA |
| Corynebacterium urealyticum DSM 7109 | cur_1766 | -256 | 5 | CAGACCAAGCTGTCTA |
|
Position: -297
Score: 4.9 Sequence: TAGACTGATCTGTCTG
Position: -217
Score: 5.4 Sequence: TAGACAGAGTTGTCTA
Locus tag: jk0242
|
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| jk0242 | -297 | 4.9 | TAGACTGATCTGTCTG | |
| -217 | 5.4 | TAGACAGAGTTGTCTA | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysJ | ||||
| Ortholog function: Ferredoxin--NADP reductase (EC 1.18.1.2) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_1361 | -98 | 4.9 | TAGACCAGTTTGTCTA |
| -63 | 5.4 | TAGACCGATTGGTCTA | ||
| Corynebacterium jeikeium K411 | jk0242 | -297 | 4.9 | TAGACTGATCTGTCTG |
| -217 | 5.4 | TAGACAGAGTTGTCTA | ||
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_1688 | -198 | 5.1 | TAGACAGAGTGGTATA |
| Corynebacterium urealyticum DSM 7109 | cur_1758 | -208 | 4.9 | CAGACCGTGCGGTCTA |
| -124 | 5 | TAGACAATGCTGTCTA | ||
|
Position: -114
Score: 5.4 Sequence: TAGACAACTCTGTCTA
Position: -34
Score: 5 Sequence: CAGACAGATCAGTCTA
Locus tag: jk0243
|
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| jk0243 | -114 | 5.4 | TAGACAACTCTGTCTA | |
| -34 | 5 | CAGACAGATCAGTCTA | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysI | ||||
| Ortholog function: Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_1359 | -113 | 4.7 | CAGACTGGTCGGTCTA |
| -77 | 5.1 | TAGACCAAACGGTCTA | ||
| Corynebacterium aurimucosum ATCC 700975 | cauri_0665 | -65 | 4.4 | AAGACTGCTTTGTCTG |
| Corynebacterium efficiens YS-314 | CE2644 | -281 | 4.4 | CCGACCACTCTGTCTA |
| -247 | 5.1 | TAGACCGCTTGGTCTG | ||
| -163 | 4.4 | TAGACCGTCCAGTCTA | ||
| -46 | 4.6 | TAGACAGATCGGTACG | ||
| Corynebacterium glutamicum ATCC 13032 | cg3118 | -286 | 5.1 | TAGACCGCTTGGTCTG |
| -201 | 5.6 | TAGACAGATCGGTCTA | ||
| -83 | 4.5 | TAGACAGAGCGGTACG | ||
| Corynebacterium jeikeium K411 | jk0243 | -114 | 5.4 | TAGACAACTCTGTCTA |
| -34 | 5 | CAGACAGATCAGTCTA | ||
| Corynebacterium urealyticum DSM 7109 | cur_1757 | -181 | 5.2 | TAGACAGCATTGTCTA |
| -97 | 4.9 | TAGACCGCACGGTCTG | ||
|
Position: -134
Score: 5.3 Sequence: TGGACAGATTGGTCTA
Position: -100
Score: 4.9 Sequence: CAGACCGATCGGTCTG
Locus tag: jk0245
|
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| jk0245 | -134 | 5.3 | TGGACAGATTGGTCTA | |
| -100 | 4.9 | CAGACCGATCGGTCTG | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysH | ||||
| Ortholog function: Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_2335 | -115 | 4.2 | TAGTCCGCTCGGTTCA |
| Corynebacterium efficiens YS-314 | CE2642 | -281 | 4.4 | CCGACCACTCTGTCTA |
| -247 | 5.1 | TAGACCGCTTGGTCTG | ||
| -163 | 4.4 | TAGACCGTCCAGTCTA | ||
| -46 | 4.6 | TAGACAGATCGGTACG | ||
| Corynebacterium glutamicum ATCC 13032 | cg3116 | -286 | 5.1 | TAGACCGCTTGGTCTG |
| -201 | 5.6 | TAGACAGATCGGTCTA | ||
| -83 | 4.5 | TAGACAGAGCGGTACG | ||
| Corynebacterium jeikeium K411 | jk0245 | -134 | 5.3 | TGGACAGATTGGTCTA |
| -100 | 4.9 | CAGACCGATCGGTCTG | ||
| Corynebacterium urealyticum DSM 7109 | cur_1744 | -219 | 4.9 | TAGACCAGGCGGTCTA |
| -111 | 5.1 | TAGACCGAGCGGTCTG | ||
|
Position: -23
Score: 4.2 Sequence: TAGACAGCAAGGACTA
Locus tag: jk0249
|
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| jk0249 | -23 | 4.2 | TAGACAGCAAGGACTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysZ | ||||
| Ortholog function: Sulfate transporter, CysZ-type | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_1360 | -205 | 5.4 | TAGACCAATCGGTCTA |
| -170 | 4.8 | TAGACAAACTGGTCTA | ||
| Corynebacterium efficiens YS-314 | CE2638 | -281 | 4.4 | CCGACCACTCTGTCTA |
| -247 | 5.1 | TAGACCGCTTGGTCTG | ||
| -163 | 4.4 | TAGACCGTCCAGTCTA | ||
| -46 | 4.6 | TAGACAGATCGGTACG | ||
| Corynebacterium glutamicum ATCC 13032 | cg3112 | -286 | 5.1 | TAGACCGCTTGGTCTG |
| -201 | 5.6 | TAGACAGATCGGTCTA | ||
| -83 | 4.5 | TAGACAGAGCGGTACG | ||
| Corynebacterium jeikeium K411 | jk0249 | -23 | 4.2 | TAGACAGCAAGGACTA |
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_1695 | -61 | 5.5 | TAGACCGCTCGGTCTA |
| Corynebacterium urealyticum DSM 7109 | cur_1740 | -219 | 4.9 | TAGACCAGGCGGTCTA |
| -111 | 5.1 | TAGACCGAGCGGTCTG | ||
|
Position: -49
Score: 3.8 Sequence: TAGACTTCCCGGTATA
Position: -35
Score: 5.2 Sequence: TAGACCGATCAGTCTA
Locus tag: jk0394
|
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| jk0394 | -49 | 3.8 | TAGACTTCCCGGTATA | |
| -35 | 5.2 | TAGACCGATCAGTCTA | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysK | ||||
| Ortholog function: Cysteine synthase (EC 2.5.1.47) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_2226 | -103 | 3.9 | TAGACGAACTGGTCTG |
| Corynebacterium aurimucosum ATCC 700975 | cauri_2144 | -74 | 4.8 | TATACCACTCAGTCTA |
| Corynebacterium diphtheriae NCTC 13129 | DIP1890 | -152 | 4.5 | TAGACCGATCGGTACG |
| -130 | 4.6 | AAGACAATTCTGTCTA | ||
| Corynebacterium efficiens YS-314 | CE2446 | -148 | 4.7 | TAGACCGATCCGTCTG |
| Corynebacterium glutamicum ATCC 13032 | cg2833 | -150 | 4.6 | TGAACAGAACTGTCTA |
| Corynebacterium jeikeium K411 | jk0394 | -35 | 5.2 | TAGACCGATCAGTCTA |
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_0419 | -152 | 4.8 | CAGACCGATCTGTCTG |
| Corynebacterium urealyticum DSM 7109 | cur_1592 | -60 | 5.3 | TAGACAGATCAGTCTA |
|
Position: -30
Score: 5.3 Sequence: TGGACAGCTCTGTCTA
Locus tag: jk0737
|
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| jk0737 | -30 | 5.3 | TGGACAGCTCTGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metF | ||||
| Ortholog function: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_0019 | -182 | 4.5 | TAGACAGCTTTGTACG |
| -70 | 4.3 | TGGACAGCTTGGTACG | ||
| Corynebacterium jeikeium K411 | jk0737 | -30 | 5.3 | TGGACAGCTCTGTCTA |
| Corynebacterium urealyticum DSM 7109 | cur_1218 | -9 | 5 | TAGACAGAGATGTCTA |
|
Position: -30
Score: 4.9 Sequence: TAGACCAAGCGGTCTG
Locus tag: jk0976
|
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| jk0976 | -30 | 4.9 | TAGACCAAGCGGTCTG | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cg1739 | ||||
| Ortholog function: GMP synthase-Glutamine amidotransferase domain (EC 6.3.5.2) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_0958 | -19 | 4.8 | TGGACTAAGCTGTCTA |
| Corynebacterium amycolatum SK46 | CORAM0001_0957 | -19 | 4.8 | TGGACTAAGCTGTCTA |
| Corynebacterium glutamicum ATCC 13032 | cg1739 | -13 | 4.4 | TAGACTAAGCGGTATG |
| Corynebacterium jeikeium K411 | jk0976 | -30 | 4.9 | TAGACCAAGCGGTCTG |
|
Position: -75
Score: 5.2 Sequence: CAGACAGCTTGGTCTA
Locus tag: jk1016
|
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| jk1016 | -75 | 5.2 | CAGACAGCTTGGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metK | ||||
| Ortholog function: S-adenosylmethionine synthetase (EC 2.5.1.6) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_0910 | -98 | 4.8 | TGAACCGCTTGGTCTA |
| Corynebacterium aurimucosum ATCC 700975 | cauri_1185 | -97 | 5.4 | TAGACCGCTTGGTCTA |
| Corynebacterium diphtheriae NCTC 13129 | DIP1325 | -116 | 5.5 | TAGACAGCTTGGTCTA |
| Corynebacterium efficiens YS-314 | CE1723 | -73 | 5.5 | TAGACAGCTTGGTCTA |
| Corynebacterium glutamicum ATCC 13032 | cg1806 | -74 | 5.5 | TAGACAGCTTGGTCTA |
| Corynebacterium jeikeium K411 | jk1016 | -75 | 5.2 | CAGACAGCTTGGTCTA |
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_0984 | -98 | 5.5 | TAGACAGCTTGGTCTA |
| Corynebacterium urealyticum DSM 7109 | cur_0975 | -110 | 5.4 | TAGACCGCTTGGTCTA |
|
Position: -105
Score: 5.2 Sequence: TGGACAGCTTTGTCTA
Locus tag: jk1352
|
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| jk1352 | -105 | 5.2 | TGGACAGCTTTGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: hom | ||||
| Ortholog function: Homoserine dehydrogenase (EC 1.1.1.3) | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_1049 | -70 | 4.6 | TAGACAGCTCGTTCTG |
| Corynebacterium efficiens YS-314 | CE1289 | -110 | 4.9 | TGAACAGCTTGGTCTA |
| Corynebacterium glutamicum ATCC 13032 | cg1337 | -113 | 4.9 | TGAACAGCTTGGTCTA |
| Corynebacterium jeikeium K411 | jk1352 | -105 | 5.2 | TGGACAGCTTTGTCTA |
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_1290 | -100 | 4.5 | CATACAGCTTTGTCTG |
| Corynebacterium urealyticum DSM 7109 | cur_0694 | -134 | 5.5 | TAGACAGCTTGGTCTA |
|
Position: -171
Score: 4.5 Sequence: TAGACCAAGCGGTATG
Position: -93
Score: 5.2 Sequence: TAGACAGAGCGGTTTA
Locus tag: jk1694
|
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| jk1694 | -171 | 4.5 | TAGACCAAGCGGTATG | |
| -93 | 5.2 | TAGACAGAGCGGTTTA | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metY | ||||
| Ortholog function: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_0291 | -73 | 5 | TAGACAGCTTGGTTCA |
| Corynebacterium aurimucosum ATCC 700975 | cauri_0513 | -92 | 4.2 | CCAACCGCTCGGTCTA |
| -27 | 4.8 | TGAACCGCTTGGTCTA | ||
| Corynebacterium diphtheriae NCTC 13129 | DIP0630 | -138 | 4.1 | CGCACCACTTTGTCTA |
| -82 | 4.6 | TAGACCGATCGGTTTC | ||
| Corynebacterium efficiens YS-314 | CE0679 | -139 | 4.6 | CGAACCGCTCGGTCTA |
| -117 | 4.9 | TAGACCGAGCGGTTCA | ||
| Corynebacterium glutamicum ATCC 13032 | cg0755 | -90 | 4.5 | TATACCACACAGTCTA |
| -68 | 4.7 | TAGACCAAGCTGTTCA | ||
| Corynebacterium jeikeium K411 | jk1694 | -171 | 4.5 | TAGACCAAGCGGTATG |
| -93 | 5.2 | TAGACAGAGCGGTTTA | ||
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_1568 | -300 | 4.6 | CATACCGCTTAGTCTA |
| -244 | 4.4 | TAGACAGGGCGGTTTG | ||
| -225 | 4.8 | TAGACCGAGCGGTACA | ||
| Corynebacterium urealyticum DSM 7109 | cur_0423 | -212 | 4.9 | TAGACCAAGTGGTATA |
| -145 | 5.2 | TAGACAGAGCGGTTTA | ||
|
Position: -103
Score: 4.5 Sequence: TAGACTAAGTTGTTCA
Locus tag: jk1710
|
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| jk1710 | -103 | 4.5 | TAGACTAAGTTGTTCA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metQ | ||||
| Ortholog function: Methionine ABC transporter substrate-binding protein | ||||
| Corynebacterium jeikeium K411 | jk1710 | -103 | 4.5 | TAGACTAAGTTGTTCA |
| Corynebacterium urealyticum DSM 7109 | cur_0411 | -127 | 4.9 | TAGACCAAGTTGTCCA |