Propagation of McbR regulog to Corynebacterium aurimucosum ATCC 700975
| Source regulog: | McbR - Corynebacteriaceae |
| Regulator type: | Transcription factor |
| Regulator family: | TetR |
| Regulation mode: | repressor |
| Biological process: | Methionine biosynthesis |
| Effector: | S-adenosylmethionine; S-adenosylhomocysteine |
| Phylum: | Actinobacteria |
| Propagated regulon: | |
| Target genome | Corynebacterium aurimucosum ATCC 700975 |
| Orthologous TF(s) | cauri_2422 |
| Regulated genes | 15 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -182
Score: 4.5 Sequence: TAGACAGCTTTGTACG
Locus tag: cauri_0019
|
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| cauri_0019 | -182 | 4.5 | TAGACAGCTTTGTACG | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metF | ||||
| Ortholog function: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_0019 | -182 | 4.5 | TAGACAGCTTTGTACG |
| -70 | 4.3 | TGGACAGCTTGGTACG | ||
| Corynebacterium jeikeium K411 | jk0737 | -30 | 5.3 | TGGACAGCTCTGTCTA |
| Corynebacterium urealyticum DSM 7109 | cur_1218 | -9 | 5 | TAGACAGAGATGTCTA |
|
Position: -6
Score: 4.7 Sequence: TAGACAATGCGGTCTG
Locus tag: cauri_0079
|
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| cauri_0079 | -6 | 4.7 | TAGACAATGCGGTCTG | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysR | ||||
| Ortholog function: Sulphur metabolism transcriptional regulator CysR, ROK family | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_0079 | -40 | 4.5 | TAGACCATGATGTCTA |
| -6 | 4.7 | TAGACAATGCGGTCTG | ||
| Corynebacterium diphtheriae NCTC 13129 | DIP0123 | -126 | 4.6 | CGTACCGATCGGTCTA |
| -37 | 4.4 | TAGACAAGCTGGTCTA | ||
| Corynebacterium glutamicum ATCC 13032 | cg0156 | -69 | 4.8 | CAGACAATGCGGTCTA |
| -36 | 5.4 | TAGACAGCGTTGTCTA | ||
|
Position: -101
Score: 4.8 Sequence: TAGACAAAGCGGTTCA
Locus tag: cauri_0499
|
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| cauri_0499 | -101 | 4.8 | TAGACAAAGCGGTTCA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metQ | ||||
| Ortholog function: Methionine ABC transporter substrate-binding protein | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_0499 | -101 | 4.8 | TAGACAAAGCGGTTCA |
| Corynebacterium aurimucosum ATCC 700975 | cauri_0498 | -101 | 4.8 | TAGACAAAGCGGTTCA |
|
Position: -27
Score: 4.8 Sequence: TGAACCGCTTGGTCTA
Locus tag: cauri_0513
|
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| cauri_0513 | -27 | 4.8 | TGAACCGCTTGGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metY | ||||
| Ortholog function: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_0291 | -73 | 5 | TAGACAGCTTGGTTCA |
| Corynebacterium aurimucosum ATCC 700975 | cauri_0513 | -92 | 4.2 | CCAACCGCTCGGTCTA |
| -27 | 4.8 | TGAACCGCTTGGTCTA | ||
| Corynebacterium diphtheriae NCTC 13129 | DIP0630 | -138 | 4.1 | CGCACCACTTTGTCTA |
| -82 | 4.6 | TAGACCGATCGGTTTC | ||
| Corynebacterium efficiens YS-314 | CE0679 | -139 | 4.6 | CGAACCGCTCGGTCTA |
| -117 | 4.9 | TAGACCGAGCGGTTCA | ||
| Corynebacterium glutamicum ATCC 13032 | cg0755 | -90 | 4.5 | TATACCACACAGTCTA |
| -68 | 4.7 | TAGACCAAGCTGTTCA | ||
| Corynebacterium jeikeium K411 | jk1694 | -171 | 4.5 | TAGACCAAGCGGTATG |
| -93 | 5.2 | TAGACAGAGCGGTTTA | ||
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_1568 | -300 | 4.6 | CATACCGCTTAGTCTA |
| -244 | 4.4 | TAGACAGGGCGGTTTG | ||
| -225 | 4.8 | TAGACCGAGCGGTACA | ||
| Corynebacterium urealyticum DSM 7109 | cur_0423 | -212 | 4.9 | TAGACCAAGTGGTATA |
| -145 | 5.2 | TAGACAGAGCGGTTTA | ||
|
Position: -180
Score: 4.3 Sequence: CAGACAAAGCAGTCTT
Locus tag: cauri_0664
|
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| cauri_0664 | -180 | 4.3 | CAGACAAAGCAGTCTT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysJ | ||||
| Ortholog function: Ferredoxin--NADP reductase (EC 1.18.1.2) | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_0664 | -180 | 4.3 | CAGACAAAGCAGTCTT |
| Corynebacterium efficiens YS-314 | CE2645 | -212 | 4.7 | TAGACTGGACGGTCTA |
| -128 | 5 | CAGACCAAGCGGTCTA | ||
| -94 | 4.4 | TAGACAGAGTGGTCGG | ||
| Corynebacterium glutamicum ATCC 13032 | cg3119 | -197 | 5.4 | TAGACCGATCTGTCTA |
| -112 | 5 | CAGACCAAGCGGTCTA | ||
|
Position: -65
Score: 4.4 Sequence: AAGACTGCTTTGTCTG
Locus tag: cauri_0665
|
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| cauri_0665 | -65 | 4.4 | AAGACTGCTTTGTCTG | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysI | ||||
| Ortholog function: Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_1359 | -113 | 4.7 | CAGACTGGTCGGTCTA |
| -77 | 5.1 | TAGACCAAACGGTCTA | ||
| Corynebacterium aurimucosum ATCC 700975 | cauri_0665 | -65 | 4.4 | AAGACTGCTTTGTCTG |
| Corynebacterium efficiens YS-314 | CE2644 | -281 | 4.4 | CCGACCACTCTGTCTA |
| -247 | 5.1 | TAGACCGCTTGGTCTG | ||
| -163 | 4.4 | TAGACCGTCCAGTCTA | ||
| -46 | 4.6 | TAGACAGATCGGTACG | ||
| Corynebacterium glutamicum ATCC 13032 | cg3118 | -286 | 5.1 | TAGACCGCTTGGTCTG |
| -201 | 5.6 | TAGACAGATCGGTCTA | ||
| -83 | 4.5 | TAGACAGAGCGGTACG | ||
| Corynebacterium jeikeium K411 | jk0243 | -114 | 5.4 | TAGACAACTCTGTCTA |
| -34 | 5 | CAGACAGATCAGTCTA | ||
| Corynebacterium urealyticum DSM 7109 | cur_1757 | -181 | 5.2 | TAGACAGCATTGTCTA |
| -97 | 4.9 | TAGACCGCACGGTCTG | ||
|
Position: -72
Score: 4.5 Sequence: TGAACCGATCGGTATA
Position: -29
Score: 4.8 Sequence: TATACAACACTGTCTA
Locus tag: cauri_0959
|
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| cauri_0959 | -72 | 4.5 | TGAACCGATCGGTATA | |
| -29 | 4.8 | TATACAACACTGTCTA | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: gltT | ||||
| Ortholog function: Predicted sodium:dicarboxylate symporter | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_0959 | -72 | 4.5 | TGAACCGATCGGTATA |
| -29 | 4.8 | TATACAACACTGTCTA | ||
| Corynebacterium glutamicum ATCC 13032 | cg2810 | -175 | 4.3 | TAGACTTATGGGTCTA |
| -118 | 5.2 | TAGACAGATCTGTTTA | ||
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_1960 | -88 | 4.4 | TAGACAGACCAGTCTG |
|
Position: -70
Score: 4.6 Sequence: TAGACAGCTCGTTCTG
Locus tag: cauri_1049
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| cauri_1049 | -70 | 4.6 | TAGACAGCTCGTTCTG | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: hom | ||||
| Ortholog function: Homoserine dehydrogenase (EC 1.1.1.3) | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_1049 | -70 | 4.6 | TAGACAGCTCGTTCTG |
| Corynebacterium efficiens YS-314 | CE1289 | -110 | 4.9 | TGAACAGCTTGGTCTA |
| Corynebacterium glutamicum ATCC 13032 | cg1337 | -113 | 4.9 | TGAACAGCTTGGTCTA |
| Corynebacterium jeikeium K411 | jk1352 | -105 | 5.2 | TGGACAGCTTTGTCTA |
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_1290 | -100 | 4.5 | CATACAGCTTTGTCTG |
| Corynebacterium urealyticum DSM 7109 | cur_0694 | -134 | 5.5 | TAGACAGCTTGGTCTA |
|
Position: -97
Score: 5.4 Sequence: TAGACCGCTTGGTCTA
Locus tag: cauri_1185
|
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| cauri_1185 | -97 | 5.4 | TAGACCGCTTGGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metK | ||||
| Ortholog function: S-adenosylmethionine synthetase (EC 2.5.1.6) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_0910 | -98 | 4.8 | TGAACCGCTTGGTCTA |
| Corynebacterium aurimucosum ATCC 700975 | cauri_1185 | -97 | 5.4 | TAGACCGCTTGGTCTA |
| Corynebacterium diphtheriae NCTC 13129 | DIP1325 | -116 | 5.5 | TAGACAGCTTGGTCTA |
| Corynebacterium efficiens YS-314 | CE1723 | -73 | 5.5 | TAGACAGCTTGGTCTA |
| Corynebacterium glutamicum ATCC 13032 | cg1806 | -74 | 5.5 | TAGACAGCTTGGTCTA |
| Corynebacterium jeikeium K411 | jk1016 | -75 | 5.2 | CAGACAGCTTGGTCTA |
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_0984 | -98 | 5.5 | TAGACAGCTTGGTCTA |
| Corynebacterium urealyticum DSM 7109 | cur_0975 | -110 | 5.4 | TAGACCGCTTGGTCTA |
|
Position: -36
Score: 5 Sequence: TAGACTGTGCTGTCTA
Locus tag: cauri_2043
|
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| cauri_2043 | -36 | 5 | TAGACTGTGCTGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cg2678 | ||||
| Ortholog function: Predicted ABC transporter, substrate-binding protein | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_2043 | -36 | 5 | TAGACTGTGCTGTCTA |
| Corynebacterium efficiens YS-314 | CE2334 | -71 | 5.5 | TAGACAGATTGGTCTA |
| -48 | 4.2 | AGTACCGATCAGTCTA | ||
| Corynebacterium glutamicum ATCC 13032 | cg2678 | -112 | 4.8 | TAGACAGGTTGGTCTG |
| -90 | 4.9 | TATACCGATCAGTCTA | ||
| Corynebacterium urealyticum DSM 7109 | cur_0251 | -41 | 5 | TAGACAGATCTGTTCA |
|
Position: -36
Score: 5 Sequence: TAGACAGCACAGTCTA
Locus tag: cauri_2044
|
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| cauri_2044 | -36 | 5 | TAGACAGCACAGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cg2679 | ||||
| Ortholog function: Conserved hypothetical protein | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_2044 | -36 | 5 | TAGACAGCACAGTCTA |
| Corynebacterium efficiens YS-314 | CE2335 | -75 | 4.1 | TAGACTGATCGGTACT |
| -52 | 5.3 | TAGACCAATCTGTCTA | ||
| Corynebacterium glutamicum ATCC 13032 | cg2679 | -72 | 5 | TAGACTGATCGGTATA |
| -50 | 4.4 | CAGACCAACCTGTCTA | ||
| Corynebacterium urealyticum DSM 7109 | cur_0252 | -61 | 4.9 | TGAACAGATCTGTCTA |
|
Position: -28
Score: 4.9 Sequence: TGAACAGCTTGGTCTA
Locus tag: cauri_2045
|
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| cauri_2045 | -28 | 4.9 | TGAACAGCTTGGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metB | ||||
| Ortholog function: Cystathionine gamma-synthase (EC 2.5.1.48) | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_2045 | -28 | 4.9 | TGAACAGCTTGGTCTA |
| Corynebacterium efficiens YS-314 | CE2343 | 1 | 5.3 | TGGACAGCTTGGTCTA |
| Corynebacterium glutamicum ATCC 13032 | cg2687 | -78 | 5.3 | TGGACAGCTTGGTCTA |
| Corynebacterium jeikeium K411 | jk0055 | -108 | 5.3 | TAGACTGCTTGGTCTA |
|
Position: -74
Score: 4.8 Sequence: TATACCACTCAGTCTA
Locus tag: cauri_2144
|
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| cauri_2144 | -74 | 4.8 | TATACCACTCAGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysK | ||||
| Ortholog function: Cysteine synthase (EC 2.5.1.47) | ||||
| Corynebacterium amycolatum SK46 | CORAM0001_2226 | -103 | 3.9 | TAGACGAACTGGTCTG |
| Corynebacterium aurimucosum ATCC 700975 | cauri_2144 | -74 | 4.8 | TATACCACTCAGTCTA |
| Corynebacterium diphtheriae NCTC 13129 | DIP1890 | -152 | 4.5 | TAGACCGATCGGTACG |
| -130 | 4.6 | AAGACAATTCTGTCTA | ||
| Corynebacterium efficiens YS-314 | CE2446 | -148 | 4.7 | TAGACCGATCCGTCTG |
| Corynebacterium glutamicum ATCC 13032 | cg2833 | -150 | 4.6 | TGAACAGAACTGTCTA |
| Corynebacterium jeikeium K411 | jk0394 | -35 | 5.2 | TAGACCGATCAGTCTA |
| Corynebacterium kroppenstedtii DSM 44385 | ckrop_0419 | -152 | 4.8 | CAGACCGATCTGTCTG |
| Corynebacterium urealyticum DSM 7109 | cur_1592 | -60 | 5.3 | TAGACAGATCAGTCTA |
|
Position: -115
Score: 4.2 Sequence: TAGTCCGCTCGGTTCA
Locus tag: cauri_2335
|
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| cauri_2335 | -115 | 4.2 | TAGTCCGCTCGGTTCA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysH | ||||
| Ortholog function: Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_2335 | -115 | 4.2 | TAGTCCGCTCGGTTCA |
| Corynebacterium efficiens YS-314 | CE2642 | -281 | 4.4 | CCGACCACTCTGTCTA |
| -247 | 5.1 | TAGACCGCTTGGTCTG | ||
| -163 | 4.4 | TAGACCGTCCAGTCTA | ||
| -46 | 4.6 | TAGACAGATCGGTACG | ||
| Corynebacterium glutamicum ATCC 13032 | cg3116 | -286 | 5.1 | TAGACCGCTTGGTCTG |
| -201 | 5.6 | TAGACAGATCGGTCTA | ||
| -83 | 4.5 | TAGACAGAGCGGTACG | ||
| Corynebacterium jeikeium K411 | jk0245 | -134 | 5.3 | TGGACAGATTGGTCTA |
| -100 | 4.9 | CAGACCGATCGGTCTG | ||
| Corynebacterium urealyticum DSM 7109 | cur_1744 | -219 | 4.9 | TAGACCAGGCGGTCTA |
| -111 | 5.1 | TAGACCGAGCGGTCTG | ||
|
Position: -57
Score: 4.4 Sequence: CATACCGGTTTGTCTA
Locus tag: cauri_2422
|
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| cauri_2422 | -57 | 4.4 | CATACCGGTTTGTCTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: mcbR | ||||
| Ortholog function: Methionine biosynthesis transcriptional regulator McbR, TetR family | ||||
| Corynebacterium aurimucosum ATCC 700975 | cauri_2422 | -57 | 4.4 | CATACCGGTTTGTCTA |
| Corynebacterium diphtheriae NCTC 13129 | DIP2274 | -74 | 4.7 | TAGACTGATCTGTTCA |
| Corynebacterium efficiens YS-314 | CE2788 | -154 | 4.1 | CGAACCGGTTTGTCTA |
| Corynebacterium glutamicum ATCC 13032 | cg3253 | -78 | 4.1 | CGAACCGGTTTGTCTA |