Propagation of McbR regulog to Corynebacterium aurimucosum ATCC 700975

Reference regulog properties
Source regulog:	McbR - Corynebacteriaceae
Regulator type:	Transcription factor
Regulator family:	TetR
Regulation mode:	repressor
Biological process:	Methionine biosynthesis
Effector:	S-adenosylmethionine; S-adenosylhomocysteine
Phylum:	Actinobacteria
Propagated regulon:
Target genome	Corynebacterium aurimucosum ATCC 700975
Orthologous TF(s)	cauri_2422
Regulated genes	15

Built upon 162 sites [see more]

Predicted regulatory interactions in *Corynebacterium aurimucosum ATCC 700975*
	Locus tag	Position	Score	Sequence
Position: -182 Score: 4.5 Sequence: TAGACAGCTTTGTACG Locus tag: cauri_0019
	cauri_0019	-182	4.5	TAGACAGCTTTGTACG
Supported by regulated orthologs from reference regulons
Ortholog gene name: metF
Ortholog function: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Corynebacterium aurimucosum ATCC 700975	cauri_0019	-182	4.5	TAGACAGCTTTGTACG
		-70	4.3	TGGACAGCTTGGTACG
Corynebacterium jeikeium K411	jk0737	-30	5.3	TGGACAGCTCTGTCTA
Corynebacterium urealyticum DSM 7109	cur_1218	-9	5	TAGACAGAGATGTCTA

Position: -6 Score: 4.7 Sequence: TAGACAATGCGGTCTG Locus tag: cauri_0079
	cauri_0079	-6	4.7	TAGACAATGCGGTCTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysR
Ortholog function: Sulphur metabolism transcriptional regulator CysR, ROK family
Corynebacterium aurimucosum ATCC 700975	cauri_0079	-40	4.5	TAGACCATGATGTCTA
		-6	4.7	TAGACAATGCGGTCTG
Corynebacterium diphtheriae NCTC 13129	DIP0123	-126	4.6	CGTACCGATCGGTCTA
		-37	4.4	TAGACAAGCTGGTCTA
Corynebacterium glutamicum ATCC 13032	cg0156	-69	4.8	CAGACAATGCGGTCTA
		-36	5.4	TAGACAGCGTTGTCTA

Position: -101 Score: 4.8 Sequence: TAGACAAAGCGGTTCA Locus tag: cauri_0499
	cauri_0499	-101	4.8	TAGACAAAGCGGTTCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metQ
Ortholog function: Methionine ABC transporter substrate-binding protein
Corynebacterium aurimucosum ATCC 700975	cauri_0499	-101	4.8	TAGACAAAGCGGTTCA
Corynebacterium aurimucosum ATCC 700975	cauri_0498	-101	4.8	TAGACAAAGCGGTTCA

Position: -27 Score: 4.8 Sequence: TGAACCGCTTGGTCTA Locus tag: cauri_0513
	cauri_0513	-27	4.8	TGAACCGCTTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metY
Ortholog function: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Corynebacterium amycolatum SK46	CORAM0001_0291	-73	5	TAGACAGCTTGGTTCA
Corynebacterium aurimucosum ATCC 700975	cauri_0513	-92	4.2	CCAACCGCTCGGTCTA
		-27	4.8	TGAACCGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP0630	-138	4.1	CGCACCACTTTGTCTA
		-82	4.6	TAGACCGATCGGTTTC
Corynebacterium efficiens YS-314	CE0679	-139	4.6	CGAACCGCTCGGTCTA
		-117	4.9	TAGACCGAGCGGTTCA
Corynebacterium glutamicum ATCC 13032	cg0755	-90	4.5	TATACCACACAGTCTA
		-68	4.7	TAGACCAAGCTGTTCA
Corynebacterium jeikeium K411	jk1694	-171	4.5	TAGACCAAGCGGTATG
		-93	5.2	TAGACAGAGCGGTTTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1568	-300	4.6	CATACCGCTTAGTCTA
		-244	4.4	TAGACAGGGCGGTTTG
		-225	4.8	TAGACCGAGCGGTACA
Corynebacterium urealyticum DSM 7109	cur_0423	-212	4.9	TAGACCAAGTGGTATA
		-145	5.2	TAGACAGAGCGGTTTA

Position: -180 Score: 4.3 Sequence: CAGACAAAGCAGTCTT Locus tag: cauri_0664
	cauri_0664	-180	4.3	CAGACAAAGCAGTCTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysJ
Ortholog function: Ferredoxin--NADP reductase (EC 1.18.1.2)
Corynebacterium aurimucosum ATCC 700975	cauri_0664	-180	4.3	CAGACAAAGCAGTCTT
Corynebacterium efficiens YS-314	CE2645	-212	4.7	TAGACTGGACGGTCTA
		-128	5	CAGACCAAGCGGTCTA
		-94	4.4	TAGACAGAGTGGTCGG
Corynebacterium glutamicum ATCC 13032	cg3119	-197	5.4	TAGACCGATCTGTCTA
		-112	5	CAGACCAAGCGGTCTA

Position: -65 Score: 4.4 Sequence: AAGACTGCTTTGTCTG Locus tag: cauri_0665
	cauri_0665	-65	4.4	AAGACTGCTTTGTCTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysI
Ortholog function: Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1)
Corynebacterium amycolatum SK46	CORAM0001_1359	-113	4.7	CAGACTGGTCGGTCTA
		-77	5.1	TAGACCAAACGGTCTA
Corynebacterium aurimucosum ATCC 700975	cauri_0665	-65	4.4	AAGACTGCTTTGTCTG
Corynebacterium efficiens YS-314	CE2644	-281	4.4	CCGACCACTCTGTCTA
		-247	5.1	TAGACCGCTTGGTCTG
		-163	4.4	TAGACCGTCCAGTCTA
		-46	4.6	TAGACAGATCGGTACG
Corynebacterium glutamicum ATCC 13032	cg3118	-286	5.1	TAGACCGCTTGGTCTG
		-201	5.6	TAGACAGATCGGTCTA
		-83	4.5	TAGACAGAGCGGTACG
Corynebacterium jeikeium K411	jk0243	-114	5.4	TAGACAACTCTGTCTA
		-34	5	CAGACAGATCAGTCTA
Corynebacterium urealyticum DSM 7109	cur_1757	-181	5.2	TAGACAGCATTGTCTA
		-97	4.9	TAGACCGCACGGTCTG

Position: -72 Score: 4.5 Sequence: TGAACCGATCGGTATA Position: -29 Score: 4.8 Sequence: TATACAACACTGTCTA Locus tag: cauri_0959
	cauri_0959	-72	4.5	TGAACCGATCGGTATA
		-29	4.8	TATACAACACTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: gltT
Ortholog function: Predicted sodium:dicarboxylate symporter
Corynebacterium aurimucosum ATCC 700975	cauri_0959	-72	4.5	TGAACCGATCGGTATA
		-29	4.8	TATACAACACTGTCTA
Corynebacterium glutamicum ATCC 13032	cg2810	-175	4.3	TAGACTTATGGGTCTA
		-118	5.2	TAGACAGATCTGTTTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1960	-88	4.4	TAGACAGACCAGTCTG

Position: -70 Score: 4.6 Sequence: TAGACAGCTCGTTCTG Locus tag: cauri_1049
	cauri_1049	-70	4.6	TAGACAGCTCGTTCTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: hom
Ortholog function: Homoserine dehydrogenase (EC 1.1.1.3)
Corynebacterium aurimucosum ATCC 700975	cauri_1049	-70	4.6	TAGACAGCTCGTTCTG
Corynebacterium efficiens YS-314	CE1289	-110	4.9	TGAACAGCTTGGTCTA
Corynebacterium glutamicum ATCC 13032	cg1337	-113	4.9	TGAACAGCTTGGTCTA
Corynebacterium jeikeium K411	jk1352	-105	5.2	TGGACAGCTTTGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_1290	-100	4.5	CATACAGCTTTGTCTG
Corynebacterium urealyticum DSM 7109	cur_0694	-134	5.5	TAGACAGCTTGGTCTA

Position: -97 Score: 5.4 Sequence: TAGACCGCTTGGTCTA Locus tag: cauri_1185
	cauri_1185	-97	5.4	TAGACCGCTTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metK
Ortholog function: S-adenosylmethionine synthetase (EC 2.5.1.6)
Corynebacterium amycolatum SK46	CORAM0001_0910	-98	4.8	TGAACCGCTTGGTCTA
Corynebacterium aurimucosum ATCC 700975	cauri_1185	-97	5.4	TAGACCGCTTGGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP1325	-116	5.5	TAGACAGCTTGGTCTA
Corynebacterium efficiens YS-314	CE1723	-73	5.5	TAGACAGCTTGGTCTA
Corynebacterium glutamicum ATCC 13032	cg1806	-74	5.5	TAGACAGCTTGGTCTA
Corynebacterium jeikeium K411	jk1016	-75	5.2	CAGACAGCTTGGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0984	-98	5.5	TAGACAGCTTGGTCTA
Corynebacterium urealyticum DSM 7109	cur_0975	-110	5.4	TAGACCGCTTGGTCTA

Position: -36 Score: 5 Sequence: TAGACTGTGCTGTCTA Locus tag: cauri_2043
	cauri_2043	-36	5	TAGACTGTGCTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cg2678
Ortholog function: Predicted ABC transporter, substrate-binding protein
Corynebacterium aurimucosum ATCC 700975	cauri_2043	-36	5	TAGACTGTGCTGTCTA
Corynebacterium efficiens YS-314	CE2334	-71	5.5	TAGACAGATTGGTCTA
		-48	4.2	AGTACCGATCAGTCTA
Corynebacterium glutamicum ATCC 13032	cg2678	-112	4.8	TAGACAGGTTGGTCTG
		-90	4.9	TATACCGATCAGTCTA
Corynebacterium urealyticum DSM 7109	cur_0251	-41	5	TAGACAGATCTGTTCA

Position: -36 Score: 5 Sequence: TAGACAGCACAGTCTA Locus tag: cauri_2044
	cauri_2044	-36	5	TAGACAGCACAGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cg2679
Ortholog function: Conserved hypothetical protein
Corynebacterium aurimucosum ATCC 700975	cauri_2044	-36	5	TAGACAGCACAGTCTA
Corynebacterium efficiens YS-314	CE2335	-75	4.1	TAGACTGATCGGTACT
		-52	5.3	TAGACCAATCTGTCTA
Corynebacterium glutamicum ATCC 13032	cg2679	-72	5	TAGACTGATCGGTATA
		-50	4.4	CAGACCAACCTGTCTA
Corynebacterium urealyticum DSM 7109	cur_0252	-61	4.9	TGAACAGATCTGTCTA

Position: -28 Score: 4.9 Sequence: TGAACAGCTTGGTCTA Locus tag: cauri_2045
	cauri_2045	-28	4.9	TGAACAGCTTGGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metB
Ortholog function: Cystathionine gamma-synthase (EC 2.5.1.48)
Corynebacterium aurimucosum ATCC 700975	cauri_2045	-28	4.9	TGAACAGCTTGGTCTA
Corynebacterium efficiens YS-314	CE2343	1	5.3	TGGACAGCTTGGTCTA
Corynebacterium glutamicum ATCC 13032	cg2687	-78	5.3	TGGACAGCTTGGTCTA
Corynebacterium jeikeium K411	jk0055	-108	5.3	TAGACTGCTTGGTCTA

Position: -74 Score: 4.8 Sequence: TATACCACTCAGTCTA Locus tag: cauri_2144
	cauri_2144	-74	4.8	TATACCACTCAGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysK
Ortholog function: Cysteine synthase (EC 2.5.1.47)
Corynebacterium amycolatum SK46	CORAM0001_2226	-103	3.9	TAGACGAACTGGTCTG
Corynebacterium aurimucosum ATCC 700975	cauri_2144	-74	4.8	TATACCACTCAGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP1890	-152	4.5	TAGACCGATCGGTACG
		-130	4.6	AAGACAATTCTGTCTA
Corynebacterium efficiens YS-314	CE2446	-148	4.7	TAGACCGATCCGTCTG
Corynebacterium glutamicum ATCC 13032	cg2833	-150	4.6	TGAACAGAACTGTCTA
Corynebacterium jeikeium K411	jk0394	-35	5.2	TAGACCGATCAGTCTA
Corynebacterium kroppenstedtii DSM 44385	ckrop_0419	-152	4.8	CAGACCGATCTGTCTG
Corynebacterium urealyticum DSM 7109	cur_1592	-60	5.3	TAGACAGATCAGTCTA

Position: -115 Score: 4.2 Sequence: TAGTCCGCTCGGTTCA Locus tag: cauri_2335
	cauri_2335	-115	4.2	TAGTCCGCTCGGTTCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysH
Ortholog function: Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
Corynebacterium aurimucosum ATCC 700975	cauri_2335	-115	4.2	TAGTCCGCTCGGTTCA
Corynebacterium efficiens YS-314	CE2642	-281	4.4	CCGACCACTCTGTCTA
		-247	5.1	TAGACCGCTTGGTCTG
		-163	4.4	TAGACCGTCCAGTCTA
		-46	4.6	TAGACAGATCGGTACG
Corynebacterium glutamicum ATCC 13032	cg3116	-286	5.1	TAGACCGCTTGGTCTG
		-201	5.6	TAGACAGATCGGTCTA
		-83	4.5	TAGACAGAGCGGTACG
Corynebacterium jeikeium K411	jk0245	-134	5.3	TGGACAGATTGGTCTA
		-100	4.9	CAGACCGATCGGTCTG
Corynebacterium urealyticum DSM 7109	cur_1744	-219	4.9	TAGACCAGGCGGTCTA
		-111	5.1	TAGACCGAGCGGTCTG

Position: -57 Score: 4.4 Sequence: CATACCGGTTTGTCTA Locus tag: cauri_2422
	cauri_2422	-57	4.4	CATACCGGTTTGTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: mcbR
Ortholog function: Methionine biosynthesis transcriptional regulator McbR, TetR family
Corynebacterium aurimucosum ATCC 700975	cauri_2422	-57	4.4	CATACCGGTTTGTCTA
Corynebacterium diphtheriae NCTC 13129	DIP2274	-74	4.7	TAGACTGATCTGTTCA
Corynebacterium efficiens YS-314	CE2788	-154	4.1	CGAACCGGTTTGTCTA
Corynebacterium glutamicum ATCC 13032	cg3253	-78	4.1	CGAACCGGTTTGTCTA

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of McbR regulog to Corynebacterium aurimucosum ATCC 700975

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --