Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagated regulons of Staphylococcus aureus subsp. aureus USA300_FPR3757

Type Regulator Effector Pathway Genes Sites
TF ArcR Arginine Arginine degradation 2 2
TF ArgR Arginine Arginine biosynthesis; Arginine degradation 10 46
TF ArsR Arsenate; Arsenite Arsenic resistance 1 1
TF BglR Beta-glucoside-6-phosphate Beta-glucosides utilization 2 2
TF BirA Biotin Biotin biosynthesis 3 3
TF CcpA HPr, phosphocarrier protein; Fructose-1,6-diphosphate Carbon catabolism 76 95
TF CggR Fructose-1,6-diphosphate Glycolysis 1 1
TF CodY Branched-chain amino acids Amino acid metabolism 73 156
TF CymR O-acetyl-L-serine; CysK, cysteine synthetase Cysteine metabolism 12 14
TF FapR Malonyl-CoA; Malonyl-ACP Fatty acid biosynthesis 5 5
TF FruR Fructose-6-phosphate Fructose utilization 1 3
TF Fur Iron ion, (Fe2+) Iron homeostasis 19 31
TF GlnR Feedback-inhibited GlnA, glutamine synthetase Nitrogen assimilation 2 2
TF GltC 2-oxoglutarate; Glutamate Glutamate metabolism 2 2
TF GlvR Maltose-6-phosphate Maltose utilization 1 1
TF GntR Gluconate Gluconate utilization 1 1
TF HisR Histidine Histidine biosynthesis 5 6
TF HrcA Heat shock Heat shock response 2 2
TF HutR Histidine Histidine utilization 3 3
TF IcaR Intercellular adhesion 2 2
TF LexA DNA damage SOS response 11 14
TF MalR Maltose Maltose utilization; Maltodextrin utilization 2 2
TF MecI Penicillin G; Methicillin Penicillin and methicillin resistance 2 4
TF MepR Bis-indoles; Distamycin Multidrug resistance 2 2
TF MntR Manganese ion, (Mn2+) Manganese homeostasis 2 2
TF MtlR MtlA, mannitol-specific enzyme IICB PTS component; HPr, phosphocarrier protein Mannitol utilization 1 1
TF MurR N-acetylmuramate-6-phosphate N-acetylmuramate utilization 1 1
TF NanR N-acetylmannosamine-6-phosphate Sialic acid utilization; N-acetylglucosamine utilization 5 5
TF NrdR Deoxyribonucleotides Deoxyribonucleotide biosynthesis 2 3
TF NreC NreB, sensor histidine kinase (Nitrate, Nitrite) Nitrate and nitrite respiration 3 3
TF PerR Hydrogen peroxide; Manganese ion, (Mn2+); Iron ion, (Fe2+) Oxidative stress response 10 15
TF Rex NADH Energy metabolism 17 17
TF SaeR SaeS, sensor histidine kinase Virulence 22 33
TF ScrR Sucrose-6-phosphate Sucrose utilization 2 3
TF YtrA Hypothetical ABC transporter 1 1
TF Zur Zinc ion, (Zn2+) Zinc homeostasis 8 8
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