Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing tdcA gene

Properties
Regulog: Crp - Enterobacteriales
Regulator type: Transcription factor
Regulator family: CRP
Regulation mode: activator (repressor)
Biological process: Carbon catabolism
Effector: Cyclic 3',5'-AMP
Phylum: Proteobacteria/gamma
Built upon 2301 sites [see more]
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Citrobacter koseri ATCC BAA-895
Position: -225
Score: 4.28912
Sequence: ATATGTTATCGCCATAAAATAT
Position: -187
Score: 3.89265
Sequence: TTTTTTGACAAAAATCATGATA
Position: -82
Score: 4.58832
Sequence: ATTTGTGAGTAGTCGCACATAA
Locus tag: CKO_04518
Name: tdcA
Funciton: Threonine catabolic operon transcriptional activator TdcA
Locus tag: CKO_04517
Name: tdcB
Funciton: Threonine dehydratase, catabolic (EC 4.3.1.19)
Locus tag: CKO_04516
Name: tdcC
Funciton: L-threonine/L-serine permease
Locus tag: CKO_04515
Name: tdcD
Funciton: Propionate kinase (EC 2.7.2.15) / Acetate kinase (EC 2.7.2.1)
Locus tag: CKO_04514
Name: tdcE
Funciton: 2-ketobutyrate formate-lyase (EC 2.3.1.-) / Pyruvate formate-lyase (EC 2.3.1.54)
Locus tag: CKO_04513
Name: yhaR
Funciton: Hypothetical protein TdcF in cluster with anaerobic degradation of L-threonine to propionate
Locus tag: CKO_04512
Name: tdcG
Funciton: Predicted L-serine dehydratase (EC 4.3.1.17) TdcG
tdcA-tdcB-tdcC-tdcD-tdcE-yhaR-tdcG -225 4.3 ATATGTTATCGCCATAAAATAT CKO_04518
-187 3.9 TTTTTTGACAAAAATCATGATA
-82 4.6 ATTTGTGAGTAGTCGCACATAA
Enterobacter sp. 638
Position: -82
Score: 3.90355
Sequence: ATTTGTGAGTAACAGCACATCC
Locus tag: Ent638_3565
Name: tdcA
Funciton: Threonine catabolic operon transcriptional activator TdcA
Locus tag: Ent638_3564
Name: tdcB
Funciton: Threonine dehydratase, catabolic (EC 4.3.1.19)
Locus tag: Ent638_3563
Name: tdcC
Funciton: L-threonine/L-serine permease
Locus tag: Ent638_3562
Name: tdcD
Funciton: Propionate kinase (EC 2.7.2.15) / Acetate kinase (EC 2.7.2.1)
Locus tag: Ent638_3561
Name: tdcE
Funciton: 2-ketobutyrate formate-lyase (EC 2.3.1.-) / Pyruvate formate-lyase (EC 2.3.1.54)
Locus tag: Ent638_3560
Name: yhaR
Funciton: Hypothetical protein TdcF in cluster with anaerobic degradation of L-threonine to propionate
tdcA-tdcB-tdcC-tdcD-tdcE-yhaR -82 3.9 ATTTGTGAGTAACAGCACATCC Ent638_3565
Escherichia coli str. K-12 substr. MG1655
Position: -225
Score: 4.04781
Sequence: TGATGTTATCGCCATAAAATAT
Position: -82
Score: 4.70499
Sequence: ATTTGTGAGTGGTCGCACATAT
Locus tag: b3118
Name: tdcA
Funciton: Threonine catabolic operon transcriptional activator TdcA
Locus tag: b3117
Name: tdcB
Funciton: Threonine dehydratase, catabolic (EC 4.3.1.19)
Locus tag: b3116
Name: tdcC
Funciton: L-threonine/L-serine permease
Locus tag: b3115
Name: tdcD
Funciton: Propionate kinase (EC 2.7.2.15) / Acetate kinase (EC 2.7.2.1)
Locus tag: b3114
Name: tdcE
Funciton: 2-ketobutyrate formate-lyase (EC 2.3.1.-) / Pyruvate formate-lyase (EC 2.3.1.54)
Locus tag: b3113
Name: yhaR
Funciton: Hypothetical protein TdcF in cluster with anaerobic degradation of L-threonine to propionate
Locus tag: b4471
Name: tdcG
Funciton: Predicted L-serine dehydratase (EC 4.3.1.17) TdcG
tdcA-tdcB-tdcC-tdcD-tdcE-yhaR-tdcG -225 4 TGATGTTATCGCCATAAAATAT b3118
-82 4.7 ATTTGTGAGTGGTCGCACATAT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Position: -82
Score: 4.64692
Sequence: CTTTGTGAGAGCTCTCACATAA
Position: -54
Score: 3.72168
Sequence: AATTGCGATTTGTTACACTTTC
Locus tag: KPN_02296
Name: tdcA
Funciton: Threonine catabolic operon transcriptional activator TdcA
Locus tag: KPN_02295
Name: tdcB
Funciton: Threonine dehydratase, catabolic (EC 4.3.1.19)
Locus tag: KPN_02294
Name: tdcC
Funciton: L-threonine/L-serine permease
Locus tag: KPN_02293
Name: tdcD
Funciton: Propionate kinase (EC 2.7.2.15) / Acetate kinase (EC 2.7.2.1)
Locus tag: KPN_02292
Name: tdcE
Funciton: 2-ketobutyrate formate-lyase (EC 2.3.1.-) / Pyruvate formate-lyase (EC 2.3.1.54)
tdcA-tdcB-tdcC-tdcD-tdcE -82 4.6 CTTTGTGAGAGCTCTCACATAA KPN_02296
-54 3.7 AATTGCGATTTGTTACACTTTC
Salmonella typhimurium LT2
Position: -188
Score: 3.9446
Sequence: TTTTTTGATTGAAATCAGGCTA
Position: -83
Score: 4.67651
Sequence: ATTTGTGAGTGGTCGCACATAA
Locus tag: STM3245
Name: tdcA
Funciton: Threonine catabolic operon transcriptional activator TdcA
Locus tag: STM3244
Name: tdcB
Funciton: Threonine dehydratase, catabolic (EC 4.3.1.19)
Locus tag: STM3243
Name: tdcC
Funciton: L-threonine/L-serine permease
Locus tag: STM3242
Name: tdcD
Funciton: Propionate kinase (EC 2.7.2.15) / Acetate kinase (EC 2.7.2.1)
Locus tag: STM3241
Name: tdcE
Funciton: 2-ketobutyrate formate-lyase (EC 2.3.1.-) / Pyruvate formate-lyase (EC 2.3.1.54)
Locus tag: STM3240
Name: tdcG
Funciton: Predicted L-serine dehydratase (EC 4.3.1.17) TdcG
tdcA-tdcB-tdcC-tdcD-tdcE-tdcG -188 3.9 TTTTTTGATTGAAATCAGGCTA STM3245
-83 4.7 ATTTGTGAGTGGTCGCACATAA
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