Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing cysG3 gene

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Phylum: Firmicutes
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Clostridium bartlettii DSM 16795
Position: -274
Score: 71.78
Sequence: AGGGAAAAAGGTACA...
Locus tag: CLOBAR_01422
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: CLOBAR_01421
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: CLOBAR_01420
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: CLOBAR_01419
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: CLOBAR_01418
Name: pduX
Funciton: Threonine kinase in B12 biosynthesis
Locus tag: CLOBAR_01417
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: CLOBAR_01416
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: CLOBAR_01415
Name: cbiE
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Locus tag: CLOBAR_01414
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: CLOBAR_01413
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: CLOBAR_01412
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: CLOBAR_01411
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: CLOBAR_01410
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: CLOBAR_01409
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
Locus tag: CLOBAR_01408
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: CLOBAR_01407
Name: hemC
Funciton: Porphobilinogen deaminase (EC 2.5.1.61)
Locus tag: CLOBAR_01406
Name: cobA-hemD
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
Locus tag: CLOBAR_01405
Name: hemB
Funciton: Porphobilinogen synthase (EC 4.2.1.24)
Locus tag: CLOBAR_01404
Name: sstT
Funciton: hypothetical protein
Locus tag: CLOBAR_01403
Name: sstT
Funciton: hypothetical protein
Locus tag: CLOBAR_01402
Name: cysG3
Funciton: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)
cbiP-cbiA-cbiB-cobD-pduX-cbiC-cbiD-cbiE-cbiT-cbiF-cbiG-cbiH-cbiJ-cbiK-cbiL-hemC-cobA-hemD-hemB-sstT-sstT-cysG3 -274 71.8 AGGGAAAAAGGTACA... CLOBAR_01422
Clostridium difficile 630
Position: -295
Score: 102.08
Sequence: GAATATTAGATTAAA...
Locus tag: CD3435
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: CD3434
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: CD3433
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: CD3432
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: CD3431
Name: pduX
Funciton: Threonine kinase in B12 biosynthesis
Locus tag: CD3430
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: CD3429
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: CD3428
Name: cbiE
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Locus tag: CD3427
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: CD3426
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: CD3425
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: CD3424
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: CD3423
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: CD3422
Name: cbiKL
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) / Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: CD3421
Name: hemC
Funciton: Porphobilinogen deaminase (EC 2.5.1.61)
Locus tag: CD3420
Name: cobA-hemD
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
Locus tag: CD3419
Name: hemB
Funciton: Porphobilinogen synthase (EC 4.2.1.24)
Locus tag: CD3418
Name: cysG3
Funciton: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)
cbiP-cbiA-cbiB-cobD-pduX-cbiC-cbiD-cbiE-cbiT-cbiF-cbiG-cbiH-cbiJ-cbiKL-hemC-cobA-hemD-hemB-cysG3 -295 102.1 GAATATTAGATTAAA... CD3435
Clostridium phytofermentans ISDg
Position: -362
Score: 109.4
Sequence: ACAATTTAGATCTTT...
Locus tag: null
Name: hemA
Funciton: Glutamyl-tRNA reductase (EC 1.2.1.70)
Locus tag: null
Name: cysG3
Funciton: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)
Locus tag: null
Name: hemC
Funciton: Porphobilinogen deaminase (EC 2.5.1.61)
Locus tag: null
Name: cobA-hemD
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
Locus tag: null
Name: hemB
Funciton: Porphobilinogen synthase (EC 4.2.1.24)
Locus tag: null
Name: hemL
Funciton: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)
Locus tag: null
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: null
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: null
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: null
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: null
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: null
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: null
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: null
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: null
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
hemA-cysG3-hemC-cobA-hemD-hemB-hemL-cbiD-cbiL-cbiF-cbiG-cbiH-cbiJ-cbiA-btuR-cbiC -362 109.4 ACAATTTAGATCTTT... null