Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing cobU gene

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Phylum: Proteobacteria
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Azotobacter vinelandii AvOP
Position: -310
Score: 91.29
Sequence: CCCTGCGCGCCTCGC...
Locus tag: Avin_33130
Name: btuB2-btuM-btuR
Funciton: Outer membrane vitamin B12 receptor BtuB / Optional hypothetical component of the B12 transporter BtuM / Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: Avin_33120
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: Avin_33110
Name: bluB
Funciton: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
Locus tag: Avin_33100
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: Avin_33090
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: Avin_33080
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: Avin_33070
Name: null
Funciton: hypothetical protein
Locus tag: Avin_33060
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: Avin_33050
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: Avin_33040
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: Avin_33030
Name: cobS
Funciton: Cobalamin synthase
btuB2-btuM-btuR-cbiA-bluB-cbiB-cobD-cbiP-Avin_33070-cobU-cobT-cobC-cobS -310 91.3 CCCTGCGCGCCTCGC... Avin_33130
Pseudomonas aeruginosa PAO1
Position: -303
Score: 82.28
Sequence: CTGCGCGCCTTGCGA...
Locus tag: PA1271
Name: btuB2
Funciton: Outer membrane vitamin B12 receptor BtuB
Locus tag: PA1272
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: PA1273
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: PA1274
Name: bluB
Funciton: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
Locus tag: PA1275
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: PA1276
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: PA1277
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: PA1278
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: PA1279
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: PA1280
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: PA1281
Name: cobS
Funciton: Cobalamin synthase
btuB2-btuR-cbiA-bluB-cbiB-cobD-cbiP-cobU-cobT-cobC-cobS -303 82.3 CTGCGCGCCTTGCGA... PA1271
Pseudomonas entomophila L48
Position: -330
Score: 96.17
Sequence: CTTCGCGGCGTGTTT...
Locus tag: PSEEN1378
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: PSEEN1379
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: PSEEN1380
Name: bluB
Funciton: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
Locus tag: PSEEN1381
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: PSEEN1382
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: PSEEN1383
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: PSEEN1384
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: PSEEN1385
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: PSEEN1386
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: PSEEN1387
Name: cobS
Funciton: Cobalamin synthase
btuR-cbiA-bluB-cbiB-cobD-cbiP-cobU-cobT-cobC-cobS -330 96.2 CTTCGCGGCGTGTTT... PSEEN1378
Pseudomonas fluorescens Pf-5
Position: -315
Score: 105.58
Sequence: ACCTTCGCGACTTGT...
Locus tag: PFL_4431
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: PFL_4430
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: PFL_4429
Name: bluB
Funciton: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
Locus tag: PFL_4428
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: PFL_4427
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: PFL_4426
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: PFL_4425
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: PFL_4424
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: PFL_4423
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: PFL_4422
Name: cobS
Funciton: Cobalamin synthase
btuR-cbiA-bluB-cbiB-cobD-cbiP-cobU-cobT-cobC-cobS -315 105.6 ACCTTCGCGACTTGT... PFL_4431
Pseudomonas mendocina ymp
Position: -394
Score: 97.27
Sequence: CTGCGCGCCTTGCTT...
Locus tag: Pmen_1750
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: Pmen_1751
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: Pmen_1752
Name: bluB
Funciton: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
Locus tag: Pmen_1753
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: Pmen_1754
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: Pmen_1755
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: Pmen_1756
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: Pmen_1757
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: Pmen_1758
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: Pmen_1759
Name: cobS
Funciton: Cobalamin synthase
btuR-cbiA-bluB-cbiB-cobD-cbiP-cobU-cobT-cobC-cobS -394 97.3 CTGCGCGCCTTGCTT... Pmen_1750
Pseudomonas putida KT2440
Position: -340
Score: 87.42
Sequence: CTTCGCGGCGTGTTT...
Locus tag: PP1672
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: PP1673
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: PP1674
Name: bluB
Funciton: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
Locus tag: PP1675
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: PP1676
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: PP1677
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: PP1678
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: PP1679
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: PP1680
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: PP1681
Name: cobS
Funciton: Cobalamin synthase
btuR-cbiA-bluB-cbiB-cobD-cbiP-cobU-cobT-cobC-cobS -340 87.4 CTTCGCGGCGTGTTT... PP1672
Pseudomonas stutzeri A1501
Position: -373
Score: 105.73
Sequence: ACCTCCGCGTCGCCT...
Locus tag: PST_1289
Name: btuB2
Funciton: Outer membrane vitamin B12 receptor BtuB
Locus tag: PST_1290
Name: btuM
Funciton: Optional hypothetical component of the B12 transporter BtuM
Locus tag: PST_1291
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: PST_1292
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: PST_1293
Name: bluB
Funciton: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
Locus tag: PST_1294
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: PST_1295
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: PST_1296
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: PST_1297
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: PST_1298
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: PST_1299
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: PST_1300
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: PST_1301
Name: cobS
Funciton: Cobalamin synthase
btuB2-btuM-btuR-cbiA-bluB-btuF-cbiB-cobD-cbiP-cobU-cobT-cobC-cobS -373 105.7 ACCTCCGCGTCGCCT... PST_1289
Pseudomonas syringae pv. tomato str. DC3000
Position: -304
Score: 113.92
Sequence: CTTCGCGGCTTGTTT...
Locus tag: PSPTO1708
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: PSPTO1709
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: PSPTO1710
Name: bluB
Funciton: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
Locus tag: PSPTO1711
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: PSPTO1712
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: PSPTO1713
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: PSPTO1714
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: PSPTO1715
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: PSPTO1716
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: PSPTO1717
Name: cobS
Funciton: Cobalamin synthase
btuR-cbiA-bluB-cbiB-cobD-cbiP-cobU-cobT-cobC-cobS -304 113.9 CTTCGCGGCTTGTTT... PSPTO1708
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