Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of MetJ in Vibrio splendidus LGP32

Properties
Regulator type: Transcription factor
TF locus tag: VS_2895
Regulator family: MetJ
Regulation mode: repressor
Biological process: Methionine metabolism; Methionine biosynthesis
Effector: S-adenosylmethionine
Regulog: MetJ - Vibrionales
Statistics of regulated genes:
- Genes 16
- Operons 11
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 218 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -210
Score: 6.7
Sequence: AGGCGTCT-(0)-GGATGGCT
Position: -89
Score: 7.4
Sequence: GGACATCT-(0)-AGACGTTT
Locus tag: VS_1144
Name: metR
Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
metR
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family

Position: -83
Score: 6.7
Sequence: GGGCGTTT-(0)-AGACGTCT
Position: -75
Score: 7.6
Sequence: AGACGTCT-(0)-AGACGTTG
Locus tag: VS_II1202
Name: metT
Funciton: Methionine transporter MetT, NhaC antiporter family
metT
Methionine transporter MetT, NhaC antiporter family

Position: -97
Score: 7.5
Sequence: AGACATAT-(0)-AGACGTCC
Position: -89
Score: 6.1
Sequence: AGACGTCC-(0)-GGAAGTGT
Position: -81
Score: 6.1
Sequence: GGAAGTGT-(0)-TGACGTCT
Locus tag: VS_2894
Name: metB
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: VS_2893
Name: metL
Funciton: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
metB
Cystathionine gamma-synthase (EC 2.5.1.48)
metL
Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)

Position: -114
Score: 6.8
Sequence: AGCCGTCT-(0)-AGACGTAA
Position: -106
Score: 6.1
Sequence: AGACGTAA-(0)-AAATATCT
Locus tag: VS_2382
Name: metN
Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: VS_2383
Name: metI
Funciton: Methionine ABC transporter permease protein
Locus tag: VS_2384
Name: metQ
Funciton: Methionine ABC transporter substrate-binding protein
metN
Methionine ABC transporter ATP-binding protein
metI
Methionine ABC transporter permease protein
metQ
Methionine ABC transporter substrate-binding protein

Position: -41
Score: 8
Sequence: AGATGTAT-(0)-AGACGTCT
Position: -33
Score: 6.6
Sequence: AGACGTCT-(0)-ACATATCT
Locus tag: VS_1677
Name: metA
Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
metA
Homoserine O-succinyltransferase (EC 2.3.1.46)

Position: -129
Score: 6.8
Sequence: AGCCGTCT-(0)-AGATGTAG
Locus tag: VS_2655
Name: metK
Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
metK
S-adenosylmethionine synthetase (EC 2.5.1.6)

Position: -177
Score: 4.7
Sequence: AGACCACT-(0)-AAACGGTC
Locus tag: VS_II0189
Name: mtsA
Funciton: Substrate-specific component MtsA of methionine-regulated ECF transporter
Locus tag: VS_II0188
Name: mtsB
Funciton: Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter
Locus tag: VS_II0187
Name: mtsC
Funciton: Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter
mtsA
Substrate-specific component MtsA of methionine-regulated ECF transporter
mtsB
Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter
mtsC
Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter

Position: -215
Score: 7
Sequence: GGATGTAT-(0)-AGATGGCT
Locus tag: VS_2998
Name: btuB
Funciton: TonB-dependent outer membrane transporter for vitamin B12
btuB
TonB-dependent outer membrane transporter for vitamin B12

Position: -66
Score: 7.3
Sequence: AGACGTCT-(0)-AGACTCCT
Locus tag: VS_0315
Name: metH
Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
metH
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)

Position: -107
Score: 5.4
Sequence: AGACGTCA-(0)-ACACTTCC
Position: -91
Score: 7.2
Sequence: GGACGTCT-(0)-ATATGTCT
Locus tag: VS_2895
Name: metJ
Funciton: S-adenosylmethionine-responsive transcriptional repressor MetJ
metJ
S-adenosylmethionine-responsive transcriptional repressor MetJ

Position: -208
Score: 7
Sequence: AAACGTCT-(0)-AGATGTCC
Position: -87
Score: 6.4
Sequence: AGCCATCC-(0)-AGACGCCT
Locus tag: VS_1145
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
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