Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagated regulons of Shigella dysenteriae 1012

Type Regulator Effector Pathway Genes Sites
TF AbgR p-aminobenzoyl-glutamate p-aminobenzoyl-glutamate utilization 2 4
TF AcrR Rhodamine 6G; Ethidium bromide; Proflavin Multidrug resistance 2 2
TF AllR Allantoin Allantoin utilization 3 3
TF AraC Arabinose Arabinose utilization 1 1
TF ArgR Arginine Arginine biosynthesis; Arginine degradation 6 17
TF AscG Cellobiose-6-phosphate; Beta-glucoside-6-phosphate Beta-glucosides utilization; Cellobiose utilization 2 3
TF Crp Cyclic 3',5'-AMP Carbon catabolism 160 403
TF CueR Copper ion, (Cu+) Copper resistance 2 2
TF DeoR Deoxyribonucleoside utilization 1 1
TF ExuR Galacturonate Galacturonate utilization 1 1
TF FabR Unsaturated acyl-ACP; Unsaturated acyl-CoA Fatty acid biosynthesis 1 1
TF FadR Palmitoyl-CoA; Oleoyl-CoA Fatty acid degradation 6 9
TF Fnr Oxygen Energy metabolism; Anaerobic metabolism 58 113
TF FruR Fructose-1-phosphate; Fructose-1,6-diphosphate Central carbohydrate metabolism 13 15
TF Fur Iron ion, (Fe2+) Iron homeostasis 20 56
TF GalR/GalS Galactose Galactose utilization 4 4
TF GlpR Glycerol 3-phosphate Glycerol utilization 3 5
TF GntR Gluconate Gluconate utilization 2 4
TF IlvY 2-Acetolactate Branched-chain amino acid biosynthesis 2 4
TF IscR Iron-sulfur cluster redox state Iron-sulfur cluster biogenesis 2 3
TF KdgR 2-keto-3-deoxygluconate Pectin and polygalacturonate utlization 5 7
TF LeuO Guanosine 3',5'-bis(diphosphate) 1 4
TF LexA DNA damage SOS response 10 13
TF LldR L-lactate Lactate utilization 1 1
TF LsrR 4,5-dihydroxypentan-2,3-dione Quorum sensing; Biofilm formation 2 4
TF LysR LL-2,6-Diaminopimelate Lysine biosynthesis 2 2
TF MarR Salicylate; Tetracycline; Chloramphenicol Antibiotic resistance 1 1
TF MetR Homocysteine Methionine biosynthesis 4 7
TF MntR Manganese ion, (Mn2+) Manganese homeostasis 2 2
TF ModE Molybdate Molybdopterin biosynthesis; Molybdenum homeostasis 1 1
TF MprA 2,4-Dinitrophenol; Carbonyl cyanide m-chlorophenylhydrazone Multidrug resistance 2 2
TF MurR N-acetylmuramate-6-phosphate N-acetylmuramate utilization 2 2
TF NadR NAD NAD biosynthesis 3 3
TF NagC N-acetylglucosamine-6-phosphate N-acetylglucosamine utilization 4 6
TF NarP Nitrate; Nitrite Nitrate and nitrite respiration 14 18
TF NikR Nickel ion, (Ni2+) Nickel homeostasis 1 1
TF NorR Nitric oxide Nitrosative stress response 2 2
TF NrdR Deoxyribonucleotides Ribonucleotide reductases 2 6
TF NsrR Nitric oxide Nitrosative stress response 5 10
TF NtrC Phosphorylated NtrB, signal histidine kinase Nitrogen assimilation 8 14
TF PaaX Phenylacetyl-CoA Phenylacetic acid degradation 2 4
TF PdhR Pyruvate Pyruvate metabolism 4 4
TF PurR Hypoxanthine; Guanine Purine metabolism 14 16
TF QorR Energy metabolism 2 2
TF RhaR Rhamnose Rhamnose utilization 2 2
TF RhaS Rhamnose Rhamnose utilization 3 3
TF RutR Uracil Pyrimidine utilization 2 2
TF SdaR Glycerate Glucarate utilization; Galactarate utilization 1 1
TF TreR Trehalose-6-phosphate Trehalose utilization 1 1
TF TrpR Tryptophan Tryptophan biosynthesis 1 1
TF TyrR Tyrosine; Phenylalanine Aromatic amino acid metabolism 5 8
TF YiaJ Ascorbate-6-phosphate L-lyxose utilization 1 1
TF ZntR Zinc ion, (Zn2+) Zinc resistance 1 1
TF Zur Zinc ion, (Zn2+) Zinc homeostasis 1 1
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