Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagated regulons of Lysinibacillus sphaericus C3-41

Type Regulator Effector Pathway Genes Sites
TF ArgR Arginine Arginine biosynthesis; Arginine degradation 6 13
TF BltR Multidrug resistance 1 1
TF BmrR Multidrug resistance 1 1
TF CcpA HPr, phosphocarrier protein Carbon catabolism 4 4
TF CcpC Citrate Citrate metabolism 1 1
TF CcpN Gluconeogenesis 1 1
TF CggR Fructose-1,6-diphosphate Glycolysis 1 1
TF CodY Guanosine triphosphate; Branched-chain amino acids Amino acid metabolism 39 68
TF CsoR Copper ion, (Cu+) Copper resistance 1 1
TF CtsR Heat shock Heat shock response 1 2
TF CymR O-acetyl-L-serine; CysK, cysteine synthetase Cysteine metabolism 6 6
TF CysL Sulfate; Sulfite; Thiosulfate Sulfite reduction 2 3
TF CzrA Zinc ion, (Zn2+); Silver ion, (Ag+); Nickel ion, (Ni2+); Copper ion, (Cu2+); Cobalt ion, (Co2+); Cadmium, ion (Cd2+) Zinc resistance; Nickel resistance; Copper resistance; Cobalt resistance; Cadmium resistance 1 1
TF FadR Palmitoyl-CoA; Oleoyl-CoA Fatty acid degradation 3 4
TF FapR Malonyl-CoA Fatty acid biosynthesis 4 4
TF Fur Iron ion, (Fe2+) Iron homeostasis 8 15
TF GlnR Feedback-inhibited GlnA, glutamine synthetase Nitrogen assimilation 1 1
TF GltC2 Glutamate; 2-oxoglutarate; RocG, glutamate dehydrogenase Glutamate metabolism 1 1
TF GntR D-gluconate; D-glucono-delta-lactone Gluconate utilization 1 1
TF HisR Histidine Histidine biosynthesis 1 1
TF HrcA Heat shock Heat shock response 1 1
TF LexA DNA damage SOS response 9 12
TF LiaR LiaS, sensor histidine kinase (bacitracin, nisin, ramoplanin, vancomycin) Cell wall-active antibiotics stress response 1 1
TF LutR L-lactate Lactate utilization 1 1
TF MhqR 2-Methylhydroquinone and catechol resistance 2 2
TF NagR N-acetylglucosamine-6-phosphate N-acetylglucosamine utilization 1 1
TF NiaR Niacin NAD biosynthesis 2 2
TF NrdR Deoxyribonucleotides Deoxyribonucleotide biosynthesis 1 2
TF NsrR Nitric oxide Nitrosative stress response 2 4
TF PerR Hydrogen peroxide; Manganese ion, (Mn2+); Iron ion, (Fe2+) Oxidative stress response; Peroxide stress response 6 6
TF PurR 5-phosphoribosyl 1-pyrophosphate Purine metabolism 4 4
TF RmgR Rhamnogalacturonides utilization 1 1
TF RocR Ornithine; L-citrulline Arginine degradation; Ornithine degradation 1 1
TF TnrA NrgB, ammonium uptake protein; NrgA, ammonium uptake protein; Feedback-inhibited GlnA, glutamine synthetase Nitrogen assimilation 26 40
TF YdfL Multidrug resistance 1 1
TF YodB/CatR Diamide; Quinone Oxidative stress response 1 2
TF YrkD Multidrug resistance 2 2
TF YtlI L-cystine transporter 4 7
TF YybA Polyamine homeostasis 2 4
TF YybR/YdeP Multidrug resistance 2 2
TF Zur Zinc ion, (Zn2+) Zinc homeostasis 2 4