Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing leuB gene

Properties
Regulog: CodY - Streptococcaceae
Regulator type: Transcription factor
Regulator family: CodY
Regulation mode: repressor (activator)
Biological process: Amino acid metabolism
Effector: Guanosine triphosphate; Branched-chain amino acids
Phylum: Firmicutes
Built upon 273 sites [see more]
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Streptococcus gallolyticus UCN34
Position: -266
Score: 4.96001
Sequence: AGTATTCAGAAAATT
Locus tag: GALLO_0758
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: GALLO_0759
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: GALLO_0760
Name: ygaE
Funciton: Predicted transmembrane protein
Locus tag: GALLO_0761
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: GALLO_0762
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-ygaE-leuC-leuD -266 5 AGTATTCAGAAAATT GALLO_0758
Streptococcus mitis B6
Position: -259
Score: 5.33012
Sequence: AATTTTCAGAAAATA
Locus tag: smi_1218
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: smi_1217
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: smi_1216
Name: ygaE
Funciton: Predicted transmembrane protein
Locus tag: smi_1215
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: smi_1214
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
Locus tag: smi_1213
Name: yfjA
Funciton: Conserved hypothetical protein
leuA-leuB-ygaE-leuC-leuD-yfjA -259 5.3 AATTTTCAGAAAATA smi_1218
Streptococcus mutans UA159
Position: -246
Score: 5.44772
Sequence: ATTTTTCAGAAAATT
Locus tag: SMU.1384
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: SMU.1383
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: SMU.1382
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: SMU.1381
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -246 5.4 ATTTTTCAGAAAATT SMU.1384
Streptococcus sanguinis SK36
Position: -269
Score: 5.33012
Sequence: AATTTTCAGAAAATA
Locus tag: SSA_0975
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: SSA_0977
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: SSA_0978
Name: ygaE
Funciton: Predicted transmembrane protein
Locus tag: SSA_0980
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: SSA_0981
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
Locus tag: SSA_0983
Name: yfjA
Funciton: Conserved hypothetical protein
leuA-leuB-ygaE-leuC-leuD-yfjA -269 5.3 AATTTTCAGAAAATA SSA_0975