Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing leuB gene

Properties
Regulator type: RNA regulatory element
Name: Leu_leader
RFAM: RF00512
Regulation mode:
Biological process: Branched-chain amino acid biosynthesis
Effector:
Phylum: Proteobacteria
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Shewanella amazonensis SB2B
Position: -110
Score: 19.96
Sequence: GCTAGCCAAGCAAAG...
Locus tag: Sama_0335
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Sama_0336
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Sama_0337
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Sama_0338
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -110 20 GCTAGCCAAGCAAAG... Sama_0335
Shewanella baltica OS155
Position: -105
Score: 21.79
Sequence: AATAGGCAAAGCATT...
Locus tag: Sbal_0386
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Sbal_0387
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Sbal_0388
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Sbal_0389
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -105 21.8 AATAGGCAAAGCATT... Sbal_0386
Shewanella denitrificans OS217
Position: -173
Score: 17.57
Sequence: GAAACACACTTACTT...
Locus tag: Sden_0334
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Sden_0335
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Sden_0336
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Sden_0337
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -173 17.6 GAAACACACTTACTT... Sden_0334
Shewanella frigidimarina NCIMB 400
Position: -212
Score: 29.92
Sequence: ACATAATGAACACAC...
Locus tag: Sfri_3820
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Sfri_3819
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Sfri_3818
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Sfri_3817
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -212 29.9 ACATAATGAACACAC... Sfri_3820
Shewanella halifaxensis HAW-EB4
Position: -212
Score: 19.28
Sequence: GTGATGAAATATAAC...
Locus tag: Shal_0438
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Shal_0439
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Shal_0440
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Shal_0441
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -212 19.3 GTGATGAAATATAAC... Shal_0438
Shewanella loihica PV-4
Position: -134
Score: 20.6
Sequence: GGAGAATGTAGTGTT...
Locus tag: Shew_3472
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Shew_3471
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Shew_3470
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Shew_3469
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -134 20.6 GGAGAATGTAGTGTT... Shew_3472
Shewanella oneidensis MR-1
Position: -111
Score: 24.15
Sequence: TCGATAGATAGGCAA...
Locus tag: SO_4236
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: SO_4235
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: SO_4234
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: SO_4233
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -111 24.1 TCGATAGATAGGCAA... SO_4236
Shewanella pealeana ATCC 700345
Position: -136
Score: 17.71
Sequence: GGAGGACTTAGTGCT...
Locus tag: Spea_3828
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Spea_3827
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Spea_3826
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Spea_3825
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -136 17.7 GGAGGACTTAGTGCT... Spea_3828
Shewanella piezotolerans WP3
Position: -192
Score: 21.21
Sequence: ACCATTTATGAAGCG...
Locus tag: swp_2213
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: swp_2214
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: swp_2215
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: swp_2216
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -192 21.2 ACCATTTATGAAGCG... swp_2213
Shewanella putrefaciens CN-32
Position: -105
Score: 22.08
Sequence: AAGAGGCAAAGCATT...
Locus tag: Sputcn32_0471
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Sputcn32_0472
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Sputcn32_0473
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Sputcn32_0474
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -105 22.1 AAGAGGCAAAGCATT... Sputcn32_0471
Shewanella sediminis HAW-EB3
Position: -194
Score: 20.76
Sequence: ATGAAAATTAAAAGT...
Locus tag: Ssed_0393
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Ssed_0394
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Ssed_0395
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Ssed_0396
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -194 20.8 ATGAAAATTAAAAGT... Ssed_0393
Shewanella sp ANA-3
Position: -111
Score: 23.81
Sequence: TCGATAGATAGGCAA...
Locus tag: Shewana3_3761
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Shewana3_3760
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Shewana3_3759
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Shewana3_3758
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -111 23.8 TCGATAGATAGGCAA... Shewana3_3761
Shewanella sp MR-4
Position: -111
Score: 21.9
Sequence: TCGATAGATAGGCAA...
Locus tag: Shewmr4_3588
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Shewmr4_3587
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Shewmr4_3586
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Shewmr4_3585
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -111 21.9 TCGATAGATAGGCAA... Shewmr4_3588
Shewanella sp MR-7
Position: -109
Score: 21.9
Sequence: GATAGATAGGCAAAG...
Locus tag: Shewmr7_0368
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Shewmr7_0369
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Shewmr7_0370
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Shewmr7_0371
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -109 21.9 GATAGATAGGCAAAG... Shewmr7_0368
Shewanella sp W3-18-1
Position: -105
Score: 22.08
Sequence: AAGAGGCAAAGCATT...
Locus tag: Sputw3181_0374
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Sputw3181_0375
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Sputw3181_0376
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Sputw3181_0377
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -105 22.1 AAGAGGCAAAGCATT... Sputw3181_0374
Shewanella woodyi ATCC 51908
Position: -199
Score: 24.84
Sequence: AGATGAATATTAGCC...
Locus tag: Swoo_4550
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Swoo_4549
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Swoo_4548
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Swoo_4547
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -199 24.8 AGATGAATATTAGCC... Swoo_4550