Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing cobT gene

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Phylum: Firmicutes
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Anoxybacillus flavithermus WK1
Position: -317
Score: 111.83
Sequence: ATATACGATCAGCAA...
Locus tag: Aflv_2185
Name: cbiW
Funciton: Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
Locus tag: Aflv_2184
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: Aflv_2183
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: Aflv_2182
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: Aflv_2181
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: Aflv_2180
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: Aflv_2179
Name: cbiX
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: Aflv_2178
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: Aflv_2177
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: Aflv_2176
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic (EC 2.1.1.-)
Locus tag: Aflv_2175
Name: cbiET
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: Aflv_2174
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: Aflv_2173
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: Aflv_2172
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: Aflv_2171
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: Aflv_2170
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: Aflv_2169
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: Aflv_2168
Name: cobA
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: Aflv_2167
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
cbiW-cbiM-cbiN-cbiQ-cbiO-cbiH-cbiX-cbiJ-cbiC-cbiD-cbiET-cbiL-cbiF-cbiG-cbiA-cbiP-cobT-cobA-btuR -317 111.8 ATATACGATCAGCAA... Aflv_2185
Bacillus halodurans C-125
Position: -253
Score: 89.81
Sequence: CTTTAATAGGCTTCT...
Locus tag: BH0284
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cobT -253 89.8 CTTTAATAGGCTTCT... BH0284
Geobacillus kaustophilus HTA426
Position: -378
Score: 117.92
Sequence: TAGGCGAGAAACAAA...
Locus tag: GK1810
Name: cbiW
Funciton: Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
Locus tag: GK1809
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: GK1808
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: GK1807
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: GK1806
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: GK1805
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: GK1804
Name: cbiX
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: GK1803
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: GK1802
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: GK1801
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic (EC 2.1.1.-)
Locus tag: GK1800
Name: cbiET
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: GK1799
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: GK1798
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: GK1797
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: GK1796
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: GK1795
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: GK1794
Name: null
Funciton: Transposase
Locus tag: GK1793
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: GK1792
Name: cobA
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: GK1791
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
cbiW-cbiM-cbiN-cbiQ-cbiO-cbiH-cbiX-cbiJ-cbiC-cbiD-cbiET-cbiL-cbiF-cbiG-cbiA-cbiP-GK1794-cobT-cobA-btuR -378 117.9 TAGGCGAGAAACAAA... GK1810
Paenibacillus sp. JDR-2
Position: -357
Score: 95.13
Sequence: ACGAATAAATCATGG...
Locus tag: Pjdr2_3355
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: Pjdr2_3354
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: Pjdr2_3353
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
Locus tag: Pjdr2_3352
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: Pjdr2_3351
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: Pjdr2_3350
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: Pjdr2_3349
Name: cobS
Funciton: Cobalamin synthase
Locus tag: Pjdr2_3348
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: Pjdr2_3347
Name: cbiZ
Funciton: Adenosylcobinamide amidohydrolase (EC 3.5.1.90)
btuF-btuC-btuD-cobT-cobU-cbiB-cobS-cobD-cbiZ -357 95.1 ACGAATAAATCATGG... Pjdr2_3355