Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Silicibacter TM1040

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Rhodobacterales
Under regulation:
- Genes 19
- Operons 6
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -336
Score: 77.8
Sequence: CGCAAGGAAATTTCG...
Locus tag: TM1040_2208
Name: cfrX
Funciton: Predicted metal-binding protein
Locus tag: TM1040_2209
Name: cobW
Funciton: CobW GTPase involved in cobalt insertion for B12 biosynthesis
Locus tag: TM1040_2210
Name: cobN
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: TM1040_2211
Name: cobG
Funciton: Cobalamin biosynthesis protein CobG
Locus tag: TM1040_2212
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: TM1040_2213
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: TM1040_2214
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
cfrX
Predicted metal-binding protein
cobW
CobW GTPase involved in cobalt insertion for B12 biosynthesis
cobN
CobN component of cobalt chelatase involved in B12 biosynthesis
cobG
Cobalamin biosynthesis protein CobG
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiH
Cobalt-precorrin-3b C17-methyltransferase

Position: -338
Score: 106.6
Sequence: ATACAACTCTGCCCT...
Locus tag: TM1040_3219
Name: ardX
Funciton: Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit
Locus tag: TM1040_3218
Name: frdX
Funciton: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
ardX
Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit
frdX
Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Position: -295
Score: 121.7
Sequence: ATCAATATCGTGTTG...
Locus tag: TM1040_0521
Name: nrdH
Funciton: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
Locus tag: TM1040_0520
Name: nrdI
Funciton: Ribonucleotide reduction protein NrdI
Locus tag: TM1040_0519
Name: nrdA
Funciton: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
Locus tag: TM1040_0518
Name: nrdB
Funciton: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
nrdH
Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
nrdI
Ribonucleotide reduction protein NrdI
nrdA
Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
nrdB
Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)

Position: -302
Score: 134.4
Sequence: CGCATGAGAGGGGCG...
Locus tag: TM1040_2933
Name: cbiW
Funciton: hypothetical protein
Locus tag: TM1040_2934
Name: btuF
Funciton: ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component
Locus tag: TM1040_2935
Name: btuC
Funciton: ABC transporter (iron.B12.siderophore.hemin) , permease component
Locus tag: TM1040_2936
Name: btuD
Funciton: ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component
cbiW
hypothetical protein
btuF
ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component
btuC
ABC transporter (iron.B12.siderophore.hemin) , permease component
btuD
ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component

Position: -308
Score: 125.5
Sequence: GCGTAGCATCCAGAC...
Locus tag: TM1040_0168
Name: RSP_0787
Funciton: hypothetical protein
RSP_0787
hypothetical protein

Position: -352
Score: 112.8
Sequence: CATTGTCGACGGCAT...
Locus tag: TM1040_2222
Name: cbtA
Funciton: Predicted cobalt transporter CbtA
cbtA
Predicted cobalt transporter CbtA
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