Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of LiuR in Pseudoalteromonas haloplanktis TAC125

Properties
Regulator type: Transcription factor
TF locus tag: PSHAa1453
Regulator family: MerR
Regulation mode: repressor
Biological process: Branched-chain amino acid degradation
Effector:
Regulog: LiuR - Alteromonadales
Statistics of regulated genes:
- Genes 26
- Operons 9
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 65 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -190
Score: 4.8
Sequence: GCTGACGTGCACGTCAAC
Position: -141
Score: 4.6
Sequence: ATTGACGTAAACATCAAC
Locus tag: PSHAa1619
Name: etfD
Funciton: Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)
etfD
Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)

Position: -60
Score: 6
Sequence: CTTTACCTTTACGTAAAC
Locus tag: PSHAa1453
Name: liuR
Funciton: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
Locus tag: PSHAa1452
Name: liuA
Funciton: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
Locus tag: PSHAa1451
Name: liuB
Funciton: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
Locus tag: PSHAa1450
Name: liuC
Funciton: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
Locus tag: PSHAa1449
Name: liuD
Funciton: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
Locus tag: PSHAa1448
Name: liuE
Funciton: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
Locus tag: PSHAa1447
Name: liuF
Funciton: Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5)
Locus tag: PSHAa1446
Name: liuG
Funciton: Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5)
liuR
Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
liuA
Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
liuB
Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
liuC
Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
liuD
Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
liuE
Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
liuF
Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5)
liuG
Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5)

Position: -113
Score: 5.3
Sequence: ATTTACGTTGGCGTAAAC
Locus tag: PSHAa1454
Name: ivdA
Funciton: 3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16)
Locus tag: PSHAa1455
Name: ivdB
Funciton: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
Locus tag: PSHAa1456
Name: ivdC
Funciton: Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
Locus tag: PSHAa1457
Name: ivdD
Funciton: Enoyl-CoA hydratase (EC 4.2.1.17)
Locus tag: PSHAa1458
Name: ivdE
Funciton: Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) / Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17)
Locus tag: PSHAa1459
Name: ivdF
Funciton: 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
Locus tag: PSHAa1460
Name: ivdG
Funciton: 3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)
ivdA
3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16)
ivdB
Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
ivdC
Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
ivdD
Enoyl-CoA hydratase (EC 4.2.1.17)
ivdE
Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) / Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17)
ivdF
3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
ivdG
3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)

Position: -129
Score: 4.6
Sequence: CTTTACTTAAAAGTTAAC
Locus tag: PSHAa0586
Name: null
Funciton: hypothetical protein
Locus tag: PSHAa0587
Name: null
Funciton: Sodium:solute symporter family protein
hypothetical protein
Sodium:solute symporter family protein

Position: -122
Score: 6.2
Sequence: GTTTACGTTCACGTAAAG
Locus tag: PSHAb0374
Name: acdH
Funciton: Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)
acdH
Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)

Position: -110
Score: 5.1
Sequence: GTTAAACTTAACGTAAAC
Locus tag: PSHAa1343
Name: yciK
Funciton: Oxidoreductase, short-chain dehydrogenase/reductase family
yciK
Oxidoreductase, short-chain dehydrogenase/reductase family

Position: -74
Score: 5.3
Sequence: CGTTACGTTCACGTAAGC
Position: -68
Score: 5
Sequence: GTTCACGTAAGCGTAAGC
Locus tag: PSHAa1167
Name: ldh
Funciton: Leucine dehydrogenase (EC 1.4.1.9)
ldh
Leucine dehydrogenase (EC 1.4.1.9)

Position: -96
Score: 4.8
Sequence: GTTGATGTTTACGTCAAT
Position: -47
Score: 4.8
Sequence: GTTGACGTGCACGTCAGC
Locus tag: PSHAa1618
Name: etfB
Funciton: Electron transfer flavoprotein, beta subunit
Locus tag: PSHAa1617
Name: etfA
Funciton: Electron transfer flavoprotein, alpha subunit
etfB
Electron transfer flavoprotein, beta subunit
etfA
Electron transfer flavoprotein, alpha subunit

Position: -132
Score: 6.3
Sequence: CTTTACGTTAACGTAAAG
Locus tag: PSHAa1632
Name: bkdA1
Funciton: Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)
Locus tag: PSHAa1631
Name: bkdA2
Funciton: Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)
Locus tag: PSHAa1630
Name: bkdB
Funciton: Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
bkdA1
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)
bkdA2
Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)
bkdB
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
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