Regulog PhnF - Mycobacteriaceae

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:
Biological process:	Phosphonate utilization; 2-aminoethylphosphonate utilization
Effector:
Phylum:	Actinobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 20 sites [see more]

Member of regulog collections

By taxonomy - Mycobacteriaceae
By TF family - GntR/Others
By pathway - Phosphonate utilization
By pathway - 2-aminoethylphosphonate utilization

Statistics of regulated genes
Genome	Genes	Operons
Mycobacterium abscessus ATCC 19977	7	2
Mycobacterium avium 104
Mycobacterium flavescens PYR-GCK
Mycobacterium leprae TN
Mycobacterium marinum M
Mycobacterium smegmatis str. MC2 155	12	5
Mycobacterium sp. JLS	8	3
Mycobacterium tuberculosis H37Rv
Mycobacterium vanbaalenii PYR-1	13	4

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes										Function

CRON 1.
phnF2	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	* Mycobacterium smegmatis str. MC2 155 Site: position = -42 score = 5.43179 sequence = CTTGGTCTATACCAGC Site: position = -100 score = 5.44887 sequence = GGTGGTCTATACCAAC Gene: MSMEG_0650: Transcriptional regulator for phosphonate utilization, GntR family	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1	Transcriptional regulator for phosphonate utilization, GntR family

CRON 2.
COG0665	* Mycobacterium abscessus ATCC 19977 Site: position = -32 score = 6.38082 sequence = ATTGGTCTAGACCAAT Site: position = -79 score = 6.35214 sequence = ATTGGTCTATACCAAT Gene: MAB_1499: Putative FAD dependent oxidoreductase	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	* Mycobacterium smegmatis str. MC2 155 Site: position = -97 score = 6.35214 sequence = ATTGGTCTATACCAAT Gene: MSMEG_0288: Putative FAD dependent oxidoreductase	* Mycobacterium sp. JLS Site: position = -89 score = 6.35214 sequence = ATTGGTCTATACCAAT Gene: Mjls_1318: Putative FAD dependent oxidoreductase	Mycobacterium tuberculosis H37Rv	* Mycobacterium vanbaalenii PYR-1 Site: position = -91 score = 6.35214 sequence = ATTGGTCTATACCAAT Gene: Mvan_0054: Putative FAD dependent oxidoreductase	Putative FAD dependent oxidoreductase
phnX	Mycobacterium abscessus ATCC 19977 Gene: MAB_1500: Phosphonoacetaldehyde hydrolase (EC 3.11.1.1)	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_4401: Phosphonoacetaldehyde hydrolase (EC 3.11.1.1)	* Mycobacterium sp. JLS Site: position = -90 score = 5.99198 sequence = ATTGGTATAGACCAGT Site: position = -32 score = 4.326 sequence = ATTGGCCCAGACCACA Gene: Mjls_1319: Phosphonoacetaldehyde hydrolase (EC 3.11.1.1)	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_0053: Phosphonoacetaldehyde hydrolase (EC 3.11.1.1)	Phosphonoacetaldehyde hydrolase (EC 3.11.1.1)
phnS	Mycobacterium abscessus ATCC 19977 Gene: MAB_1501: Probable 2-aminoethylphosphonate ABC transporter, periplasmic protein	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	* Mycobacterium smegmatis str. MC2 155 Site: position = -135 score = 6.02203 sequence = ATTGGTCTATACCAAA Gene: MSMEG_6668: Probable 2-aminoethylphosphonate ABC transporter, periplasmic protein	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	* Mycobacterium vanbaalenii PYR-1 Site: position = -135 score = 6.35214 sequence = ATTGGTCTATACCAAT Gene: Mvan_5734: Probable 2-aminoethylphosphonate ABC transporter, periplasmic protein	Probable 2-aminoethylphosphonate ABC transporter, periplasmic protein
phnT	Mycobacterium abscessus ATCC 19977 Gene: MAB_1502: Probable 2-aminoethylphosphonate ABC transporter, ATP-binding protein	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_6671: Probable 2-aminoethylphosphonate ABC transporter, ATP-binding protein	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_5731: Probable 2-aminoethylphosphonate ABC transporter, ATP-binding protein	Probable 2-aminoethylphosphonate ABC transporter, ATP-binding protein
phnU	Mycobacterium abscessus ATCC 19977 Gene: MAB_1503: Probable 2-aminoethylphosphonate ABC transporter, permease protein 1	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_6669: Probable 2-aminoethylphosphonate ABC transporter, permease protein 1	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_5733: Probable 2-aminoethylphosphonate ABC transporter, permease protein 1	Probable 2-aminoethylphosphonate ABC transporter, permease protein 1
phnV	Mycobacterium abscessus ATCC 19977 Gene: MAB_1504: Probable 2-aminoethylphosphonate ABC transporter, permease protein 2	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_6670: Probable 2-aminoethylphosphonate ABC transporter, permease protein 2	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_5732: Probable 2-aminoethylphosphonate ABC transporter, permease protein 2	Probable 2-aminoethylphosphonate ABC transporter, permease protein 2
COG1524	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_6672: Alkaline phosphodiesterase I (EC 3.1.4.1) / Nucleotide pyrophosphatase (EC 3.6.1.9)	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_5730: Alkaline phosphodiesterase I (EC 3.1.4.1) / Nucleotide pyrophosphatase (EC 3.6.1.9)	Alkaline phosphodiesterase I (EC 3.1.4.1) / Nucleotide pyrophosphatase (EC 3.6.1.9)
phnD	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	* Mycobacterium smegmatis str. MC2 155 Site: position = -98 score = 5.44887 sequence = GTTGGTATAGACCACC Site: position = -156 score = 5.43179 sequence = GCTGGTATAGACCAAG Gene: MSMEG_0649: Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1)	Mycobacterium sp. JLS Gene: Mjls_1320: Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1)	Mycobacterium tuberculosis H37Rv	* Mycobacterium vanbaalenii PYR-1 Site: position = -208 score = 6.02203 sequence = ATTGGTATAGACCAAA Gene: Mvan_2904: Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1)	Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1)
phnC	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_0647: Phosphonate ABC transporter ATP-binding protein	Mycobacterium sp. JLS Gene: Mjls_1321: Phosphonate ABC transporter ATP-binding protein	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_2905: Phosphonate ABC transporter ATP-binding protein	Phosphonate ABC transporter ATP-binding protein
phnE	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_0646: Phosphonate ABC transporter permease protein phnE (TC 3.A.1.9.1)	Mycobacterium sp. JLS Gene: Mjls_1322: Phosphonate ABC transporter permease protein phnE (TC 3.A.1.9.1)	Mycobacterium tuberculosis H37Rv	* Mycobacterium vanbaalenii PYR-1 Site: position = -122 score = 4.45161 sequence = ATGGGTATCTACCAGC Gene: Mvan_2906: Phosphonate ABC transporter permease protein phnE (TC 3.A.1.9.1)	Phosphonate ABC transporter permease protein phnE (TC 3.A.1.9.1)
COG1063	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_4400: Phosphonate catabolism associated alcohol dehydrogenase	Mycobacterium sp. JLS Gene: Mjls_1323: Phosphonate catabolism associated alcohol dehydrogenase	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_2907: Phosphonate catabolism associated alcohol dehydrogenase	Phosphonate catabolism associated alcohol dehydrogenase

CRON 3.
COG4341	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	* Mycobacterium smegmatis str. MC2 155 Site: position = -34 score = 6.35214 sequence = ATTGGTATAGACCAAT Gene: MSMEG_0287: HD phosphohydrolase-like protein	* Mycobacterium sp. JLS Site: position = -34 score = 6.35214 sequence = ATTGGTATAGACCAAT Gene: Mjls_1317: HD phosphohydrolase-like protein	Mycobacterium tuberculosis H37Rv	* Mycobacterium vanbaalenii PYR-1 Site: position = -15 score = 6.35214 sequence = ATTGGTATAGACCAAT Gene: Mvan_0055: HD phosphohydrolase-like protein	HD phosphohydrolase-like protein
phnF	* Mycobacterium abscessus ATCC 19977 Site: position = -151 score = 6.35214 sequence = ATTGGTATAGACCAAT Site: position = -198 score = 6.38082 sequence = ATTGGTCTAGACCAAT Gene: MAB_1498c: Transcriptional regulator for phosphonate utilization, GntR family	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_0286: Transcriptional regulator for phosphonate utilization, GntR family	Mycobacterium sp. JLS Gene: Mjls_1316: Transcriptional regulator for phosphonate utilization, GntR family	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_0056: Transcriptional regulator for phosphonate utilization, GntR family	Transcriptional regulator for phosphonate utilization, GntR family

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog PhnF - Mycobacteriaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --