Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulog NiaR - Clostridia-2

Properties
Regulator type: Transcription factor
Regulator family: NiaR
Regulation mode: repressor
Biological process: NAD biosynthesis
Effector: Niacin
Phylum: Firmicutes
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 9 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Clostridium bartlettii DSM 16795 5 3
Clostridium difficile 630 4 2
Clostridium hiranonis DSM 13275
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
niaR
*
Clostridium bartlettii DSM 16795

Site:
position = -204
score = 6.38176
sequence = TACACGTGTATTTACACTTGTA

Site:
position = -216
score = 5.52907
sequence = TTTAAAAGTATTTACACGTGTA

Gene: CLOBAR_00530: NAD biosynthesis transcription regulator, HTH_11 family
 
Clostridium difficile 630

Gene: CD0012: NAD biosynthesis transcription regulator, HTH_11 family
 
Clostridium hiranonis DSM 13275
NAD biosynthesis transcription regulator, HTH_11 family
 
CRON 2.
niaY
*
Clostridium bartlettii DSM 16795

Site:
position = -77
score = 5.54825
sequence = TTTACATGTAATTTCATTTGTA

Site:
position = -89
score = 5.31805
sequence = TTTAAATGTAAATTTACATGTA

Gene: CLOBAR_02625: Predicted nicotinate-regulated transporter NiaY
*
Clostridium difficile 630

Site:
position = -80
score = 4.57444
sequence = AACATTTGTCTTGTCAGCTGAA

Site:
position = -92
score = 4.41714
sequence = TTTTAGTGAAATAACATTTGTC

Gene: CD2256: Predicted nicotinate-regulated transporter NiaY
 
Clostridium hiranonis DSM 13275
Predicted nicotinate-regulated transporter NiaY
 
CRON 3.
nadA
*
Clostridium bartlettii DSM 16795

Site:
position = -49
score = 6.38176
sequence = TACAAGTGTAAATACACGTGTA

Site:
position = -37
score = 5.52907
sequence = TACACGTGTAAATACTTTTAAA

Gene: CLOBAR_00531: Quinolinate synthetase (EC 4.1.99.-)
*
Clostridium difficile 630

Site:
position = -43
score = 6.03774
sequence = TACAGGTGTATATACACTAGTA

Gene: CD2372: Quinolinate synthetase (EC 4.1.99.-)
 
Clostridium hiranonis DSM 13275

Gene: CLOHIR_00157: Quinolinate synthetase (EC 4.1.99.-)
Quinolinate synthetase (EC 4.1.99.-)
nadB
 
Clostridium bartlettii DSM 16795

Gene: CLOBAR_00532: L-aspartate oxidase (EC 1.4.3.16)
 
Clostridium difficile 630

Gene: CD2371: L-aspartate oxidase (EC 1.4.3.16)
 
Clostridium hiranonis DSM 13275

Gene: CLOHIR_00158: L-aspartate oxidase (EC 1.4.3.16)
L-aspartate oxidase (EC 1.4.3.16)
nadC
 
Clostridium bartlettii DSM 16795

Gene: CLOBAR_00533: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
 
Clostridium difficile 630

Gene: CD2370: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
 
Clostridium hiranonis DSM 13275

Gene: CLOHIR_00159: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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