Statistics of regulated genes

Genome	Genes	Operons
Haemophilus influenzae Rd KW20	20	12
Aggregatibacter aphrophilus NJ8700	31	12
Pasteurella multocida subsp. multocida str. Pm70	41	16
Mannheimia succiniciproducens MBEL55E	14	5
Actinobacillus succinogenes 130Z	11	4
Haemophilus somnus 2336	17	8
Actinobacillus pleuropneumoniae serovar 7 str. AP76	37	16
Haemophilus ducreyi 35000HP	11	7
Haemophilus parasuis SH0165	13	6

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes										Function
CRON 1.
tyrS	* Haemophilus influenzae Rd KW20 Site: position = -160 score = 4.70281 sequence = GCTATTGATAACAATTATC Site: position = -190 score = 4.08539 sequence = AGGAATTATTTTCATTTAA Gene: HI1610: Tyrosyl-tRNA synthetase (EC 6.1.1.1)	* Aggregatibacter aphrophilus NJ8700 Site: position = -192 score = 4.30702 sequence = AAATTTGAGAACCATTATC Site: position = -186 score = 5.046 sequence = GAGAACCATTATCATTTTC Site: position = -224 score = 4.47079 sequence = GAGAATAATTTTTATTAAA Gene: NT05HA_0976: Tyrosyl-tRNA synthetase (EC 6.1.1.1)	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0755: Tyrosyl-tRNA synthetase (EC 6.1.1.1)	Mannheimia succiniciproducens MBEL55E Gene: MS1232: Tyrosyl-tRNA synthetase (EC 6.1.1.1)	* Actinobacillus succinogenes 130Z Site: position = -187 score = 4.10691 sequence = GAGAACGATTATCATGCAC Site: position = -228 score = 4.18405 sequence = ATAATTGAGAATTATTTGC Gene: Asuc_1827: Tyrosyl-tRNA synthetase (EC 6.1.1.1)	Haemophilus somnus 2336 Gene: HSM_0310: Tyrosyl-tRNA synthetase (EC 6.1.1.1)	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -240 score = 4.05481 sequence = TCAAATGATAAAGATTCTC Site: position = -183 score = 5.24289 sequence = GAGAATTATTATCATTAAC Site: position = -234 score = 4.46081 sequence = GATAAAGATTCTCATTTGT Gene: APP7_1484: Tyrosyl-tRNA synthetase (EC 6.1.1.1)	* Haemophilus ducreyi 35000HP Site: position = -178 score = 5.33481 sequence = GAGAATCATTATCATTAAC Site: position = -184 score = 4.40345 sequence = TGCATTGAGAATCATTATC Gene: HD0693: Tyrosyl-tRNA synthetase (EC 6.1.1.1)	* Haemophilus parasuis SH0165 Site: position = -157 score = 4.0558 sequence = GATAATTATTATCATCTAG Site: position = -163 score = 4.77232 sequence = CTTTATGATAATTATTATC Gene: HAPS_1651: Tyrosyl-tRNA synthetase (EC 6.1.1.1)	Tyrosyl-tRNA synthetase (EC 6.1.1.1)
CRON 2.
hpt	* Haemophilus influenzae Rd KW20 Site: position = -200 score = 4.42703 sequence = GAAATTGAGAATAATTCTT Site: position = -194 score = 4.28371 sequence = GAGAATAATTCTTATTGAC Gene: HI1153: Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8)	* Aggregatibacter aphrophilus NJ8700 Site: position = -272 score = 4.51523 sequence = TCAAATGATAATAATTCTT Site: position = -266 score = 4.57047 sequence = GATAATAATTCTTATTGAC Gene: NT05HA_1447: Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8)	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -229 score = 4.35463 sequence = GCAAATGATAATAATTCCT Site: position = -223 score = 4.20307 sequence = GATAATAATTCCTATTGAC Gene: PM0121: Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8)	* Mannheimia succiniciproducens MBEL55E Site: position = -240 score = 4.58309 sequence = TTAAATGATAATAATTCTT Site: position = -234 score = 4.57047 sequence = GATAATAATTCTTATTGAC Gene: MS0683: Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8)	* Actinobacillus succinogenes 130Z Site: position = -159 score = 5.2292 sequence = GACAATGATTCTCATTATC Gene: Asuc_0811: Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8)	Haemophilus somnus 2336 Gene: HSM_0762: Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8)	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -55 score = 4.55771 sequence = AGTATTAATTGTCATTATC Site: position = -49 score = 4.42232 sequence = AATTGTCATTATCATTACC Gene: APP7_0722: Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8)	Haemophilus ducreyi 35000HP Gene: HD1399: Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8)	Haemophilus parasuis SH0165 Gene: HAPS_0362: Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8)	Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8)
CRON 3.
cjrA	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	* Haemophilus parasuis SH0165 Site: position = -69 score = 5.35562 sequence = TAAAATGATAATTATTATC Site: position = -63 score = 4.64392 sequence = GATAATTATTATCAATTGA Gene: HAPS_1569: hypothetical protein	hypothetical protein
cjrC	* Haemophilus influenzae Rd KW20 Site: position = -39 score = 4.70521 sequence = GATAATCATAATATTTCTC Gene: HI1217: TonB-dependent receptor	* Aggregatibacter aphrophilus NJ8700 Site: position = -56 score = 4.771 sequence = GATAATAAGAATAATTCTT Site: position = -50 score = 4.24674 sequence = AAGAATAATTCTTATTTAA Gene: NT05HA_2308: TonB-dependent receptor	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	* Haemophilus somnus 2336 Site: position = -107 score = 4.55739 sequence = AATAATAATAAAAATTATT Site: position = -104 score = 5.13865 sequence = AATAATAAAAATTATTATC Site: position = -98 score = 5.00845 sequence = AAAAATTATTATCATTAAT Gene: HSM_0047: TonB-dependent receptor	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165 Gene: HAPS_1568: TonB-dependent receptor	TonB-dependent receptor
CRON 4.
hugX	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -310 score = 4.10793 sequence = AAAAATGATTTTAGATATT Site: position = -135 score = 4.05596 sequence = ATAATTAAAAACTATTATC Site: position = -129 score = 4.50632 sequence = AAAAACTATTATCAATATT Gene: PM0298: Putative heme iron utilization protein	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	* Haemophilus somnus 2336 Site: position = -123 score = 5.12155 sequence = AAAAATTATAATAATTATC Site: position = -57 score = 4.28234 sequence = ACAATTAAGAATAATTATC Site: position = -51 score = 4.90872 sequence = AAGAATAATTATCATTTAT Gene: HSM_1170: Putative heme iron utilization protein	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	* Haemophilus parasuis SH0165 Site: position = -135 score = 5.30428 sequence = ATAAATAATAATCATTATC Gene: HAPS_1055: Putative heme iron utilization protein	Putative heme iron utilization protein
hugZ	* Haemophilus influenzae Rd KW20 Site: position = -36 score = 4.19413 sequence = AATAATAAAAATTAATTGT Gene: HI0854: Putative heme iron utilization protein	Aggregatibacter aphrophilus NJ8700	*2 Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0299: Putative heme iron utilization protein Site: position = -46 score = 4.75835 sequence = GCAAATAAAAATTATTATC Site: position = -40 score = 4.72861 sequence = AAAAATTATTATCATTAAG Gene: PM0042: Putative heme iron utilization protein	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336 Gene: HSM_1169: Putative heme iron utilization protein	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -68 score = 4.27718 sequence = ATAATTAATAATCGTTTTT Site: position = -62 score = 4.80001 sequence = AATAATCGTTTTTATTATC Gene: APP7_1104: Putative heme iron utilization protein	Haemophilus ducreyi 35000HP Gene: HD0620: Putative heme iron utilization protein	Haemophilus parasuis SH0165 Gene: HAPS_1056: Putative heme iron utilization protein	Putative heme iron utilization protein
hgp	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0300: Probable hemoglobin and hemoglobin-haptoglobin-binding protein, TonB-dependent receptor	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_1103: Probable hemoglobin and hemoglobin-haptoglobin-binding protein, TonB-dependent receptor	* Haemophilus ducreyi 35000HP Site: position = -73 score = 4.34611 sequence = GTTTTTGATAATCGTTTTT Site: position = -67 score = 4.32128 sequence = GATAATCGTTTTTATTAAA Gene: HD2025: Probable hemoglobin and hemoglobin-haptoglobin-binding protein, TonB-dependent receptor	Haemophilus parasuis SH0165	Probable hemoglobin and hemoglobin-haptoglobin-binding protein, TonB-dependent receptor
CRON 5.
hemR	* Haemophilus influenzae Rd KW20 Site: position = -33 score = 4.6004 sequence = ATAAATAATTATCATTAAG Gene: HI0113: TonB-dependent hemin receptor, outer membrane protein	Aggregatibacter aphrophilus NJ8700	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -35 score = 5.00578 sequence = AATAATAAAAATGATTATC Site: position = -29 score = 4.97171 sequence = AAAAATGATTATCATTAAG Gene: PM0576: TonB-dependent hemin receptor, outer membrane protein	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336 Gene: HSM_1176: TonB-dependent hemin receptor, outer membrane protein	Actinobacillus pleuropneumoniae serovar 7 str. AP76	* Haemophilus ducreyi 35000HP Site: position = -74 score = 5.07439 sequence = AAAAATGATAATTATTACC Site: position = -68 score = 4.55552 sequence = GATAATTATTACCAATTTA Gene: HD0388: TonB-dependent hemin receptor, outer membrane protein	Haemophilus parasuis SH0165	TonB-dependent hemin receptor, outer membrane protein
CRON 6.
nrfA	* Haemophilus influenzae Rd KW20 Site: position = -160 score = 4.56517 sequence = GATAATAATACTCAAAATT Site: position = 26 score = 5.06625 sequence = GATATTAATAATAATTCTC Gene: HI1069: Cytochrome c552 precursor (EC 1.7.2.2)	Aggregatibacter aphrophilus NJ8700	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -39 score = 4.52974 sequence = TTTAATGATAAAAATTATC Site: position = -33 score = 4.41431 sequence = GATAAAAATTATCATTTAG Gene: PM0023: Cytochrome c552 precursor (EC 1.7.2.2)	* Mannheimia succiniciproducens MBEL55E Site: position = -294 score = 4.20863 sequence = GTAAATGATTCTAACTTTT Site: position = -84 score = 4.61752 sequence = GATAAAAATTCTCATTTTT Gene: MS1819: Cytochrome c552 precursor (EC 1.7.2.2)	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Cytochrome c552 precursor (EC 1.7.2.2)
nrfB	Haemophilus influenzae Rd KW20 Gene: HI1068: Cytochrome c-type protein NrfB precursor	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0024: Cytochrome c-type protein NrfB precursor	Mannheimia succiniciproducens MBEL55E Gene: MS1818: Cytochrome c-type protein NrfB precursor	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Cytochrome c-type protein NrfB precursor
nrfC	Haemophilus influenzae Rd KW20 Gene: HI1067: NrfC protein	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0025: NrfC protein	Mannheimia succiniciproducens MBEL55E Gene: MS1817: NrfC protein	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	NrfC protein
nrfD	Haemophilus influenzae Rd KW20 Gene: HI1066: NrfD protein	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0026: NrfD protein	Mannheimia succiniciproducens MBEL55E Gene: MS1816: NrfD protein	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	NrfD protein
nrfE	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0027: Cytochrome c-type heme lyase subunit nrfE, nitrite reductase complex assembly	Mannheimia succiniciproducens MBEL55E Gene: MS1815: Cytochrome c-type heme lyase subunit nrfE, nitrite reductase complex assembly	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Cytochrome c-type heme lyase subunit nrfE, nitrite reductase complex assembly
CRON 7.
ftr1	Haemophilus influenzae Rd KW20	* Aggregatibacter aphrophilus NJ8700 Site: position = -52 score = 4.67329 sequence = GATAATTGTTATCAATTAC Gene: NT05HA_0572: High-affinity Fe2+/Pb2+ permease	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -33 score = 4.90679 sequence = GAATATAATAATCACTATC Site: position = -27 score = 4.24213 sequence = AATAATCACTATCATTTGG Gene: PM0453: High-affinity Fe2+/Pb2+ permease	Mannheimia succiniciproducens MBEL55E	* Actinobacillus succinogenes 130Z Site: position = -32 score = 4.2011 sequence = CTAATTGATAATCAATTTT Site: position = -26 score = 4.59321 sequence = GATAATCAATTTTATTTAC Gene: Asuc_1663: High-affinity Fe2+/Pb2+ permease	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	High-affinity Fe2+/Pb2+ permease
tpd	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0571: Uncharacterized protein probably involved in high-affinity Fe2+ transport	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0452: Uncharacterized protein probably involved in high-affinity Fe2+ transport	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z Gene: Asuc_1664: Uncharacterized protein probably involved in high-affinity Fe2+ transport	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Uncharacterized protein probably involved in high-affinity Fe2+ transport
COG4393	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0570: integral membrane protein	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0451: integral membrane protein	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z Gene: Asuc_1665: integral membrane protein	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	integral membrane protein
salY	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0569: ABC-type antimicrobial peptide transport system, permease component	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0450: ABC-type antimicrobial peptide transport system, permease component	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z Gene: Asuc_1666: ABC-type antimicrobial peptide transport system, permease component	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	ABC-type antimicrobial peptide transport system, permease component
lolE	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0568: ABC-type transport system, involved in lipoprotein release, permease component	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0449: ABC-type transport system, involved in lipoprotein release, permease component	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z Gene: Asuc_1667: ABC-type transport system, involved in lipoprotein release, permease component	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	ABC-type transport system, involved in lipoprotein release, permease component
salX	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0567: ABC-type antimicrobial peptide transport system, ATPase component	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0448: ABC-type antimicrobial peptide transport system, ATPase component	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z Gene: Asuc_1668: ABC-type antimicrobial peptide transport system, ATPase component	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	ABC-type antimicrobial peptide transport system, ATPase component
tpx	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0566: Putative thioredoxin precursor	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0447: Putative thioredoxin precursor	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z Gene: Asuc_1669: Putative thioredoxin precursor	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Putative thioredoxin precursor
PF00034	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0565: Cytochrome C553 (soluble cytochrome f)	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0446: Cytochrome C553 (soluble cytochrome f)	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z Gene: Asuc_1670: Cytochrome C553 (soluble cytochrome f)	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Cytochrome C553 (soluble cytochrome f)
CRON 8.
sitA	* Haemophilus influenzae Rd KW20 Site: position = -127 score = 4.50472 sequence = TATTTTGATAATCATTCCC Site: position = -121 score = 4.20175 sequence = GATAATCATTCCCATTCCA Gene: HI0362: Manganese ABC transporter, periplasmic-binding protein SitA	* Aggregatibacter aphrophilus NJ8700 Site: position = -97 score = 4.27206 sequence = TTATTTGATAATCATTTGC Site: position = -91 score = 4.34827 sequence = GATAATCATTTGCATTTAA Gene: NT05HA_0397: Manganese ABC transporter, periplasmic-binding protein SitA	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -93 score = 4.34006 sequence = AAATTTGAGAATCATTTTT Site: position = -87 score = 4.70261 sequence = GAGAATCATTTTTATTTAC Gene: PM0400: Manganese ABC transporter, periplasmic-binding protein SitA	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	* Haemophilus somnus 2336 Site: position = -103 score = 4.15983 sequence = GATAATTATTGCTATTTAC Gene: HSM_0199: Manganese ABC transporter, periplasmic-binding protein SitA	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -54 score = 4.43505 sequence = GAGATTTATTCTCAATTTC Gene: APP7_0274: Manganese ABC transporter, periplasmic-binding protein SitA	* Haemophilus ducreyi 35000HP Site: position = -57 score = 4.29741 sequence = GCGAATTATTCTCAATAAC Gene: HD1816: Manganese ABC transporter, periplasmic-binding protein SitA	* Haemophilus parasuis SH0165 Site: position = -92 score = 4.75371 sequence = GTTATTGAGAATCATTTTT Site: position = -86 score = 4.42788 sequence = GAGAATCATTTTTATTTGT Gene: HAPS_1097: Manganese ABC transporter, periplasmic-binding protein SitA	Manganese ABC transporter, periplasmic-binding protein SitA
sitB	Haemophilus influenzae Rd KW20 Gene: HI0361: Manganese ABC transporter, ATP-binding protein SitB	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0396: Manganese ABC transporter, ATP-binding protein SitB	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0399: Manganese ABC transporter, ATP-binding protein SitB	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336 Gene: HSM_0198: Manganese ABC transporter, ATP-binding protein SitB	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0273: Manganese ABC transporter, ATP-binding protein SitB	Haemophilus ducreyi 35000HP Gene: HD1817: Manganese ABC transporter, ATP-binding protein SitB	Haemophilus parasuis SH0165 Gene: HAPS_1098: Manganese ABC transporter, ATP-binding protein SitB	Manganese ABC transporter, ATP-binding protein SitB
sitC	Haemophilus influenzae Rd KW20 Gene: HI0360: Manganese ABC transporter, inner membrane permease protein SitC	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0395: Manganese ABC transporter, inner membrane permease protein SitC	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0398: Manganese ABC transporter, inner membrane permease protein SitC	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336 Gene: HSM_0197: Manganese ABC transporter, inner membrane permease protein SitC	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0130: Manganese ABC transporter, inner membrane permease protein SitC	Haemophilus ducreyi 35000HP Gene: HD1025: Manganese ABC transporter, inner membrane permease protein SitC	Haemophilus parasuis SH0165 Gene: HAPS_1099: Manganese ABC transporter, inner membrane permease protein SitC	Manganese ABC transporter, inner membrane permease protein SitC
sitD	Haemophilus influenzae Rd KW20 Gene: HI0359: Manganese ABC transporter, inner membrane permease protein SitD	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0394: Manganese ABC transporter, inner membrane permease protein SitD	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0397: Manganese ABC transporter, inner membrane permease protein SitD	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336 Gene: HSM_0196: Manganese ABC transporter, inner membrane permease protein SitD	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0129: Manganese ABC transporter, inner membrane permease protein SitD	Haemophilus ducreyi 35000HP Gene: HD1024: Manganese ABC transporter, inner membrane permease protein SitD	Haemophilus parasuis SH0165 Gene: HAPS_1100: Manganese ABC transporter, inner membrane permease protein SitD	Manganese ABC transporter, inner membrane permease protein SitD
CRON 9.
APP7_2040	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -118 score = 4.07719 sequence = GGTAAGAAAAATAATTCTC Site: position = -112 score = 4.71401 sequence = AAAAATAATTCTCATTTAT Site: position = -71 score = 4.05469 sequence = GTTTATAATTGTAATTATT Site: position = -68 score = 4.27582 sequence = TATAATTGTAATTATTTGT Gene: APP7_2040: hypothetical protein	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	hypothetical protein
hpuB	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_2099: Hemoglobin-haptoglobin utilization protein B	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -77 score = 4.77218 sequence = TTTAATAAAAATTATTATC Site: position = -71 score = 5.22926 sequence = AAAAATTATTATCATTATT Gene: PM0741: Hemoglobin-haptoglobin utilization protein B	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	*3 Haemophilus somnus 2336 Site: position = -37 score = 4.06505 sequence = ATTAATAAGATTGATTCTT Site: position = -31 score = 4.46962 sequence = AAGATTGATTCTTATTTTT Gene: HSM_0932: Hemoglobin-haptoglobin utilization protein B Gene: HSM_0931: Hemoglobin-haptoglobin utilization protein B Site: position = -108 score = 4.45243 sequence = AATTATAAGAACCATTCTC Gene: HSM_1988: Hemoglobin-haptoglobin utilization protein B	3 Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_2041: Hemoglobin-haptoglobin utilization protein B Gene: APP7_2042: Hemoglobin-haptoglobin utilization protein B Gene: APP7_2043: Hemoglobin-haptoglobin utilization protein B	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Hemoglobin-haptoglobin utilization protein B
CRON 10.
cbiK	Haemophilus influenzae Rd KW20 Gene: HI1427: ABC-type Co2+ transport system, periplasmic component	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0772: ABC-type Co2+ transport system, periplasmic component	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	* Actinobacillus succinogenes 130Z Site: position = -73 score = 4.70144 sequence = TTTATTGATAATAATTCTC Site: position = -67 score = 5.01867 sequence = GATAATAATTCTCATTTAT Gene: Asuc_0426: ABC-type Co2+ transport system, periplasmic component	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	ABC-type Co2+ transport system, periplasmic component
CRON 11.
nrdA	Haemophilus influenzae Rd KW20	* Aggregatibacter aphrophilus NJ8700 Site: position = -48 score = 4.83218 sequence = AGGATTTATTATCATTATC Site: position = -42 score = 4.28381 sequence = TATTATCATTATCGATAAC Gene: NT05HA_0827: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0150: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165 Gene: HAPS_1342: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
nrdB	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0828: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -202 score = 4.05134 sequence = ATATTTGATTATAATTAAT Gene: APP7_0149: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165 Gene: HAPS_1341: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
CRON 12.
ceuA	Haemophilus influenzae Rd KW20	* Aggregatibacter aphrophilus NJ8700 Site: position = -40 score = 4.17922 sequence = ATACATGAGAATTATTTTC Site: position = -34 score = 4.26554 sequence = GAGAATTATTTTCAATTAT Gene: NT05HA_1146: ABC-type enterochelin transport system, periplasmic component	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS0795: ABC-type enterochelin transport system, periplasmic component	Actinobacillus succinogenes 130Z Gene: Asuc_1820: ABC-type enterochelin transport system, periplasmic component	Haemophilus somnus 2336	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -50 score = 4.6097 sequence = ATTATTGCTAATCATTTTC Site: position = -44 score = 4.43644 sequence = GCTAATCATTTTCATTACA Gene: APP7_0756: ABC-type enterochelin transport system, periplasmic component	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	ABC-type enterochelin transport system, periplasmic component
ceuB	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_1147: ABC-type enterochelin transport system, permease component	Pasteurella multocida subsp. multocida str. Pm70	* Mannheimia succiniciproducens MBEL55E Site: position = -29 score = 4.13675 sequence = AGAATTAAAAATAATTCTC Site: position = -23 score = 4.65582 sequence = AAAAATAATTCTCATTTGT Gene: MS0792: ABC-type enterochelin transport system, permease component	Actinobacillus succinogenes 130Z Gene: Asuc_1823: ABC-type enterochelin transport system, permease component	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0757: ABC-type enterochelin transport system, permease component	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	ABC-type enterochelin transport system, permease component
ceuC	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_1148: ABC-type enterochelin transport system, permease component	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS0793: ABC-type enterochelin transport system, permease component	Actinobacillus succinogenes 130Z Gene: Asuc_1822: ABC-type enterochelin transport system, permease component	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0758: ABC-type enterochelin transport system, permease component	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	ABC-type enterochelin transport system, permease component
ceuD	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_1149: ABC-type enterochelin transport system, ATPase component	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS0794: ABC-type enterochelin transport system, ATPase component	Actinobacillus succinogenes 130Z Gene: Asuc_1821: ABC-type enterochelin transport system, ATPase component	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0759: ABC-type enterochelin transport system, ATPase component	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	ABC-type enterochelin transport system, ATPase component
CRON 13.
hutW	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -76 score = 4.2385 sequence = ATTGATAAGAATCAATATC Site: position = -70 score = 4.70019 sequence = AAGAATCAATATCATTTAC Gene: APP7_1583: Radical SAM family protein HutW, similar to coproporphyrinogen III oxidase, oxygen-independent, associated with heme uptake / Putative heme iron utilization protein # hutX	* Haemophilus ducreyi 35000HP Site: position = -80 score = 4.32389 sequence = GTTGATAAAAATCAATATC Gene: HD0037: Radical SAM family protein HutW, similar to coproporphyrinogen III oxidase, oxygen-independent, associated with heme uptake / Putative heme iron utilization protein # hutX	Haemophilus parasuis SH0165	Radical SAM family protein HutW, similar to coproporphyrinogen III oxidase, oxygen-independent, associated with heme uptake / Putative heme iron utilization protein # hutX
COG0702	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_1582: hypothetical protein	Haemophilus ducreyi 35000HP Gene: HD0038: hypothetical protein	Haemophilus parasuis SH0165	hypothetical protein
CRON 14.
fecB	Haemophilus influenzae Rd KW20	* Aggregatibacter aphrophilus NJ8700 Site: position = -74 score = 4.10616 sequence = AAGAACTATTCTCAATATT Gene: NT05HA_1294: Iron(III) dicitrate transport system, periplasmic iron-binding protein FecB (TC 3.A.1.14.1)	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -81 score = 4.82383 sequence = AAAAATAATAATTACTTTC Site: position = -75 score = 4.33476 sequence = AATAATTACTTTCATTTGC Gene: PM0131: Iron(III) dicitrate transport system, periplasmic iron-binding protein FecB (TC 3.A.1.14.1)	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Iron(III) dicitrate transport system, periplasmic iron-binding protein FecB (TC 3.A.1.14.1)
fecC	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_1295: Iron(III) dicitrate transport system permease protein FecC (TC 3.A.1.14.1)	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0130: Iron(III) dicitrate transport system permease protein FecC (TC 3.A.1.14.1)	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Iron(III) dicitrate transport system permease protein FecC (TC 3.A.1.14.1)
fecD	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_1296: ABC transporter, iron chelate uptake transporter (FeCT) family, permease protein	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0129: ABC transporter, iron chelate uptake transporter (FeCT) family, permease protein	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	ABC transporter, iron chelate uptake transporter (FeCT) family, permease protein
fecE	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_1297: Iron(III) dicitrate transport ATP-binding protein FecE (TC 3.A.1.14.1)	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0128: Iron(III) dicitrate transport ATP-binding protein FecE (TC 3.A.1.14.1)	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Iron(III) dicitrate transport ATP-binding protein FecE (TC 3.A.1.14.1)
CRON 15.
COG2822	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -59 score = 4.74268 sequence = GATAATGATTATTAATAAG Site: position = -65 score = 4.32134 sequence = TGTTTTGATAATGATTATT Gene: APP7_0708: Predicted periplasmic lipoprotein involved in iron transport	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Predicted periplasmic lipoprotein involved in iron transport
COG2387	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0709: Predicted iron-dependent peroxidase	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Predicted iron-dependent peroxidase
ftr1	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0710: High-affinity Fe2+/Pb2+ permease	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	High-affinity Fe2+/Pb2+ permease
CRON 16.
hgpB	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	*2 Pasteurella multocida subsp. multocida str. Pm70 Site: position = -45 score = 4.34409 sequence = TATAATGAGAACGATTTTT Site: position = -39 score = 4.16474 sequence = GAGAACGATTTTTATTCAT Gene: PM0337: Probable hemoglobin and hemoglobin-haptoglobin-binding protein, TonB-dependent receptor Site: position = -59 score = 4.35298 sequence = GAGAACGATTTTTATAATC Site: position = -53 score = 4.76575 sequence = GATTTTTATAATCAATATC Site: position = -47 score = 4.29987 sequence = TATAATCAATATCAATCTA Gene: PM0336: Probable hemoglobin and hemoglobin-haptoglobin-binding protein, TonB-dependent receptor	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336 Gene: HSM_1168: Probable hemoglobin and hemoglobin-haptoglobin-binding protein, TonB-dependent receptor	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Probable hemoglobin and hemoglobin-haptoglobin-binding protein, TonB-dependent receptor
CRON 17.
icdA	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM1606: Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)	Mannheimia succiniciproducens MBEL55E Gene: MS2370: Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	* Haemophilus parasuis SH0165 Site: position = -193 score = 4.79999 sequence = TAAAATTATTTTCATTATT Gene: HAPS_2276: Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)	Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)
CRON 18.
lldD	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -53 score = 4.79919 sequence = CTTAATGATAATTAATATC Site: position = -47 score = 4.75493 sequence = GATAATTAATATCATTAAA Gene: PM0288: L-lactate dehydrogenase (EC 1.1.2.3)	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	L-lactate dehydrogenase (EC 1.1.2.3)
CRON 19.
irp	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	3 Pasteurella multocida subsp. multocida str. Pm70 Gene: PM1428: iron-regulated outer membrane protein/TonB-dependent receptor Gene: PM0745: iron-regulated outer membrane protein/TonB-dependent receptor Gene: PM1081: iron-regulated outer membrane protein/TonB-dependent receptor	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	* Haemophilus somnus 2336 Site: position = -71 score = 4.74149 sequence = AAAAATGATTATTGTTTTT Gene: HSM_1962: iron-regulated outer membrane protein/TonB-dependent receptor	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -31 score = 4.36872 sequence = ATTAACCATAATTATTTTA Gene: APP7_0978: iron-regulated outer membrane protein/TonB-dependent receptor	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165 Gene: HAPS_0355: iron-regulated outer membrane protein/TonB-dependent receptor	iron-regulated outer membrane protein/TonB-dependent receptor
CRON 20.
pbg	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_1600: Porphobilinogen deaminase (EC 2.5.1.61)	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM1812: Porphobilinogen deaminase (EC 2.5.1.61)	Mannheimia succiniciproducens MBEL55E Gene: MS0276: Porphobilinogen deaminase (EC 2.5.1.61)	Actinobacillus succinogenes 130Z Gene: Asuc_0356: Porphobilinogen deaminase (EC 2.5.1.61)	Haemophilus somnus 2336 Gene: HSM_1937: Porphobilinogen deaminase (EC 2.5.1.61)	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -123 score = 4.7482 sequence = TATAATAATTATCATAAAT Gene: APP7_1067: Porphobilinogen deaminase (EC 2.5.1.61)	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165 Gene: HAPS_1006: Porphobilinogen deaminase (EC 2.5.1.61)	Porphobilinogen deaminase (EC 2.5.1.61)
hemX	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_1599: Uroporphyrinogen III synthase HEM4	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM1813: Uroporphyrinogen III synthase HEM4	Mannheimia succiniciproducens MBEL55E Gene: MS0275: Uroporphyrinogen III synthase HEM4	Actinobacillus succinogenes 130Z Gene: Asuc_0355: Uroporphyrinogen III synthase HEM4	Haemophilus somnus 2336 Gene: HSM_1938: Uroporphyrinogen III synthase HEM4	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_1066: Uroporphyrinogen III synthase HEM4	Haemophilus ducreyi 35000HP Gene: HD1742: Uroporphyrinogen III synthase HEM4	Haemophilus parasuis SH0165 Gene: HAPS_1005: Uroporphyrinogen III synthase HEM4	Uroporphyrinogen III synthase HEM4
hemX	Haemophilus influenzae Rd KW20 Gene: HI0603m: HemX protein	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_1598: HemX protein	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM1814: HemX protein	Mannheimia succiniciproducens MBEL55E Gene: MS0274: HemX protein	Actinobacillus succinogenes 130Z Gene: Asuc_0354: HemX protein	Haemophilus somnus 2336 Gene: HSM_1939: HemX protein	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_1065: HemX protein	Haemophilus ducreyi 35000HP Gene: HD1741: HemX protein	Haemophilus parasuis SH0165 Gene: HAPS_1004: HemX protein	HemX protein
hemY	Haemophilus influenzae Rd KW20 Gene: HI0602: HemY protein	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_1597: HemY protein	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM1815: HemY protein	Mannheimia succiniciproducens MBEL55E Gene: MS0273: HemY protein	Actinobacillus succinogenes 130Z Gene: Asuc_0353: HemY protein	Haemophilus somnus 2336 Gene: HSM_1940: HemY protein	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_1064: HemY protein	Haemophilus ducreyi 35000HP Gene: HD1740: HemY protein	Haemophilus parasuis SH0165 Gene: HAPS_1003: HemY protein	HemY protein
CRON 21.
hgp2	* Haemophilus influenzae Rd KW20 Site: position = -85 score = 4.44289 sequence = AATAATGAGAATAGTTTTT Site: position = 2 score = 4.9268 sequence = GAGAATTATTATTATTTTT Gene: HI0661: Probable hemoglobin and hemoglobin-haptoglobin-binding protein, TonB-dependent receptor	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Probable hemoglobin and hemoglobin-haptoglobin-binding protein, TonB-dependent receptor
CRON 22.
fcuA	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	*2 Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0607: Ferrichrome receptor, TonB-dependent Site: position = -125 score = 4.91323 sequence = GATAATGATTTTCAATAAT Site: position = -131 score = 4.99577 sequence = GTTATTGATAATGATTTTC Gene: APP7_0606: Ferrichrome receptor, TonB-dependent	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Ferrichrome receptor, TonB-dependent
CRON 23.
hex	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS1111: Beta-hexosaminidase (EC 3.2.1.52)	Actinobacillus succinogenes 130Z Gene: Asuc_0859: Beta-hexosaminidase (EC 3.2.1.52)	Haemophilus somnus 2336	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -64 score = 4.71208 sequence = AAAATTGAGAATTATTTTC Gene: APP7_1152: Beta-hexosaminidase (EC 3.2.1.52)	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Beta-hexosaminidase (EC 3.2.1.52)
CRON 24.
hgpA	Haemophilus influenzae Rd KW20	* Aggregatibacter aphrophilus NJ8700 Site: position = -74 score = 4.97925 sequence = GAAAATAAATTTCATTATC Site: position = -50 score = 4.27981 sequence = GCGAATTATTTTCATTTAT Gene: NT05HA_1269: Probable hemoglobin and hemoglobin-haptoglobin-binding protein, TonB-dependent receptor	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Probable hemoglobin and hemoglobin-haptoglobin-binding protein, TonB-dependent receptor
CRON 25.
iga	* Haemophilus influenzae Rd KW20 Site: position = -198 score = 5.04712 sequence = AAAAATTATTATCATTACC Site: position = -204 score = 4.46465 sequence = AATATCAAAAATTATTATC Gene: HI0990: Immunoglobulin A1 protease autotransporter (EC 3.4.21.72)	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Immunoglobulin A1 protease autotransporter (EC 3.4.21.72)
CRON 26.
fbpA	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -32 score = 4.66306 sequence = AAGAATAATTATCATTGAC Gene: PM0051: Ferric iron ABC transporter, iron-binding protein	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	* Haemophilus somnus 2336 Site: position = -93 score = 4.16308 sequence = AAGAATAATTCTTATTGAC Gene: HSM_1250: Ferric iron ABC transporter, iron-binding protein	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165 Gene: HAPS_1129: Ferric iron ABC transporter, iron-binding protein	Ferric iron ABC transporter, iron-binding protein
fbpB	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0050: Ferric iron ABC transporter, permease protein	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336 Gene: HSM_1249: Ferric iron ABC transporter, permease protein	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165 Gene: HAPS_1128: Ferric iron ABC transporter, permease protein	Ferric iron ABC transporter, permease protein
fbpC	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0049: Ferric iron ABC transporter, ATP-binding protein	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336 Gene: HSM_1248: Ferric iron ABC transporter, ATP-binding protein	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165 Gene: HAPS_1127: Ferric iron ABC transporter, ATP-binding protein	Ferric iron ABC transporter, ATP-binding protein
CRON 27.
exbB	* Haemophilus influenzae Rd KW20 Site: position = -62 score = 4.13506 sequence = ATGATTGAAATTCATTCTC Site: position = -56 score = 4.19235 sequence = GAAATTCATTCTCAATTAT Gene: HI0253: Ferric siderophore transport system, biopolymer transport protein ExbB	* Aggregatibacter aphrophilus NJ8700 Site: position = -89 score = 4.38971 sequence = CAAAATGAGATTGATTATC Site: position = -83 score = 4.1509 sequence = GAGATTGATTATCAGTTGT Gene: NT05HA_1575: Ferric siderophore transport system, biopolymer transport protein ExbB	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -67 score = 4.37775 sequence = GAAATTAATTCTCAATACC Gene: PM1186: Ferric siderophore transport system, biopolymer transport protein ExbB	* Mannheimia succiniciproducens MBEL55E Site: position = -70 score = 4.19235 sequence = GAAATTCATTCTCAATTAT Gene: MS0515: Ferric siderophore transport system, biopolymer transport protein ExbB	Actinobacillus succinogenes 130Z Gene: Asuc_2012: Ferric siderophore transport system, biopolymer transport protein ExbB	* Haemophilus somnus 2336 Site: position = -55 score = 4.55562 sequence = GAAATTAATTCTCAATAAC Gene: HSM_1102: Ferric siderophore transport system, biopolymer transport protein ExbB	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -63 score = 4.25929 sequence = GCAAACCATTTTCATTATA Gene: APP7_0078: Ferric siderophore transport system, biopolymer transport protein ExbB	* Haemophilus ducreyi 35000HP Site: position = -125 score = 4.30496 sequence = GAAAATAACAATTATTGTC Gene: HD0329: Ferric siderophore transport system, biopolymer transport protein ExbB	Haemophilus parasuis SH0165 Gene: HAPS_1366: Ferric siderophore transport system, biopolymer transport protein ExbB	Ferric siderophore transport system, biopolymer transport protein ExbB
exbD	Haemophilus influenzae Rd KW20 Gene: HI0252: TonB system transport protein ExbD type-2/biopolymer transport protein	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_1574: TonB system transport protein ExbD type-2/biopolymer transport protein	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM1187: TonB system transport protein ExbD type-2/biopolymer transport protein	Mannheimia succiniciproducens MBEL55E Gene: MS0514: TonB system transport protein ExbD type-2/biopolymer transport protein	Actinobacillus succinogenes 130Z Gene: Asuc_2011: TonB system transport protein ExbD type-2/biopolymer transport protein	Haemophilus somnus 2336 Gene: HSM_1101: TonB system transport protein ExbD type-2/biopolymer transport protein	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0077: TonB system transport protein ExbD type-2/biopolymer transport protein	Haemophilus ducreyi 35000HP Gene: HD0328: TonB system transport protein ExbD type-2/biopolymer transport protein	Haemophilus parasuis SH0165 Gene: HAPS_1365: TonB system transport protein ExbD type-2/biopolymer transport protein	TonB system transport protein ExbD type-2/biopolymer transport protein
tonB	Haemophilus influenzae Rd KW20 Gene: HI0251: Ferric siderophore transport system, periplasmic binding protein TonB	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_1573: Ferric siderophore transport system, periplasmic binding protein TonB	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM1188: Ferric siderophore transport system, periplasmic binding protein TonB	Mannheimia succiniciproducens MBEL55E Gene: MS0513: Ferric siderophore transport system, periplasmic binding protein TonB	Actinobacillus succinogenes 130Z Gene: Asuc_2010: Ferric siderophore transport system, periplasmic binding protein TonB	Haemophilus somnus 2336 Gene: HSM_1100: Ferric siderophore transport system, periplasmic binding protein TonB	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0076: Ferric siderophore transport system, periplasmic binding protein TonB	Haemophilus ducreyi 35000HP Gene: HD0327: Ferric siderophore transport system, periplasmic binding protein TonB	Haemophilus parasuis SH0165 Gene: HAPS_1364: Ferric siderophore transport system, periplasmic binding protein TonB	Ferric siderophore transport system, periplasmic binding protein TonB
CRON 28.
cirA	Haemophilus influenzae Rd KW20	* Aggregatibacter aphrophilus NJ8700 Site: position = -95 score = 4.16623 sequence = AAGCATAGTAATAATTATC Site: position = -89 score = 5.12516 sequence = AGTAATAATTATCATTTGC Gene: NT05HA_1365: Outer membrane receptor proteins, mostly Fe transport, TonB-dependent	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_1350: Outer membrane receptor proteins, mostly Fe transport, TonB-dependent	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Outer membrane receptor proteins, mostly Fe transport, TonB-dependent
CRON 29.
hasR	Haemophilus influenzae Rd KW20	* Aggregatibacter aphrophilus NJ8700 Site: position = -31 score = 4.33048 sequence = TAAAATTATAATTATATTT Gene: NT05HA_1311: Iron siderophore receptor protein, TonB-dependent receptor	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -50 score = 5.4327 sequence = GTTAATGATTTTCATTATC Gene: PM1622: Iron siderophore receptor protein, TonB-dependent receptor	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Iron siderophore receptor protein, TonB-dependent receptor
CRON 30.
hbp	*2 Haemophilus influenzae Rd KW20 Site: position = -33 score = 5.03047 sequence = AATAATTATTATCATTAAA Site: position = -36 score = 4.3545 sequence = TATAATAATTATTATCATT Site: position = -39 score = 4.641 sequence = ATGTATAATAATTATTATC Site: position = -134 score = 4.20754 sequence = AAAAATGATTTTCTTTTAT Gene: HI0712: Hemoglobin-binding protein, TonB-dependent receptor Site: position = -67 score = 4.27959 sequence = ATATATGACAATTATTATC Site: position = -61 score = 4.56635 sequence = GACAATTATTATCATTAAG Site: position = -232 score = 4.19178 sequence = AATCATCATAATGATTACT Gene: HI0635: Hemoglobin-binding protein, TonB-dependent receptor	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Hemoglobin-binding protein, TonB-dependent receptor
CRON 31.
hmuT	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -150 score = 4.52635 sequence = GATAATTGTTATTATTTTG Site: position = -156 score = 4.91261 sequence = TATAATGATAATTGTTATT Gene: PM1078: Hemin-binding periplasmic protein hmuT precursor	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	* Haemophilus parasuis SH0165 Site: position = -34 score = 4.09319 sequence = TAAAATAAGAACCTTTATC Gene: HAPS_1572: Hemin-binding periplasmic protein hmuT precursor	Hemin-binding periplasmic protein hmuT precursor
hmuU	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM1079: Hemin transport system permease protein hmuU	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165 Gene: HAPS_1571: Hemin transport system permease protein hmuU	Hemin transport system permease protein hmuU
hmuV	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM1080: hemin transport system ATP-binding protein HmuV	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165 Gene: HAPS_1570: hemin transport system ATP-binding protein HmuV	hemin transport system ATP-binding protein HmuV
CRON 32.
fhuC	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	* Mannheimia succiniciproducens MBEL55E Site: position = -17 score = 4.52225 sequence = AATAATGAGAATAAATTTT Gene: MS1201: Ferrichrome ABC transport system, ATP-binding protein	Actinobacillus succinogenes 130Z Gene: Asuc_1020: Ferrichrome ABC transport system, ATP-binding protein	Haemophilus somnus 2336	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -56 score = 4.06297 sequence = TTAAATGCTAATAATTTTT Gene: APP7_2100: Ferrichrome ABC transport system, ATP-binding protein	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Ferrichrome ABC transport system, ATP-binding protein
fhuD	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z Gene: Asuc_1019: Ferrichrome ABC transport system, periplasmic component	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_2101: Ferrichrome ABC transport system, periplasmic component	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Ferrichrome ABC transport system, periplasmic component
Asuc_1018	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z Gene: Asuc_1018: Ferrichrome ABC transport system, permease protein	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_2102: Ferrichrome ABC transport system, permease protein	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Ferrichrome ABC transport system, permease protein
fhuA	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z Gene: Asuc_1017: Ferrichrome-iron receptor, TonB-dependent	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_2103: Ferrichrome-iron receptor, TonB-dependent	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Ferrichrome-iron receptor, TonB-dependent
CRON 33.
ssb	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -132 score = 4.55229 sequence = AAAAATGTTTTTTATTATC Gene: APP7_0845: Single-stranded DNA-binding protein	* Haemophilus ducreyi 35000HP Site: position = -126 score = 4.60771 sequence = AAAAATTTTAATTATTATC Gene: HD1285: Single-stranded DNA-binding protein	Haemophilus parasuis SH0165 Gene: HAPS_0372: Single-stranded DNA-binding protein	Single-stranded DNA-binding protein

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