Regulog ExuR - Enterobacteriales

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:	repressor
Biological process:	Galacturonate utilization
Effector:	Galacturonate
Phylum:	Proteobacteria/gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 48 sites [see more]

Member of regulog collections

By trascription factor - ExuR/UxuR
By taxonomy - Enterobacteriales
By TF family - GntR/Others
By effector - Galacturonate
By pathway - Galacturonate utilization

Statistics of regulated genes
Genome	Genes	Operons
Escherichia coli str. K-12 substr. MG1655	5	4
Salmonella typhimurium LT2
Citrobacter koseri ATCC BAA-895	10	8
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	8	7
Enterobacter sp. 638	9	7
Erwinia amylovora ATCC 49946
Yersinia pestis KIM	7	5
Serratia proteamaculans 568	9	7
Erwinia carotovora subsp. atroseptica SCRI1043	4	4
Edwardsiella tarda EIB202	8	6
Proteus mirabilis HI4320
Photorhabdus luminescens subsp. laumondii TTO1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes													Function

CRON 1.
exuR	* Escherichia coli str. K-12 substr. MG1655 Site: position = -47 score = 5.99123 sequence = AAAGTGGTATAACAAATAT Gene: b3094: D-galacturonate transcriptional repressor, GntR family	Salmonella typhimurium LT2	* Citrobacter koseri ATCC BAA-895 Site: position = -47 score = 5.99123 sequence = AAAGTGGTATAACAAATAT Gene: CKO_04496: D-galacturonate transcriptional repressor, GntR family	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -48 score = 5.78866 sequence = AAAGTGGTATAACAAATCG Gene: KPN_03522: D-galacturonate transcriptional repressor, GntR family	* Enterobacter sp. 638 Site: position = -45 score = 6.07467 sequence = AAAGTGGTATAACAAATCA Gene: Ent638_3548: D-galacturonate transcriptional repressor, GntR family	Erwinia amylovora ATCC 49946	* Yersinia pestis KIM Site: position = -105 score = 5.83319 sequence = TAAGTGGTATAACAAATCC Gene: y3602: D-galacturonate transcriptional repressor, GntR family	* Serratia proteamaculans 568 Site: position = -57 score = 5.83319 sequence = TAAGTGGTATAACAAATCC Gene: Spro_4323: D-galacturonate transcriptional repressor, GntR family	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -98 score = 5.87839 sequence = TAAGTGGTATAACAAATCA Gene: ECA0643: D-galacturonate transcriptional repressor, GntR family	* Edwardsiella tarda EIB202 Site: position = -68 score = 5.83373 sequence = AAAGTGGTATAACAACTCG Gene: ETAE_0434: D-galacturonate transcriptional repressor, GntR family	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	D-galacturonate transcriptional repressor, GntR family

CRON 2.
uxuB	2 Escherichia coli str. K-12 substr. MG1655 Gene: b4323: D-mannonate oxidoreductase (EC 1.1.1.57) Gene: b2172: D-mannonate oxidoreductase (EC 1.1.1.57)	Salmonella typhimurium LT2 Gene: STM3136: D-mannonate oxidoreductase (EC 1.1.1.57)	* Citrobacter koseri ATCC BAA-895 Site: position = -191 score = 4.42562 sequence = AAGTTGTTATACCAAATTA Gene: CKO_00608: D-mannonate oxidoreductase (EC 1.1.1.57)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -193 score = 3.72557 sequence = AAAGTtGTtatACcAaTaa Gene: KPN_02605: D-mannonate oxidoreductase (EC 1.1.1.57)	* Enterobacter sp. 638 Site: position = -193 score = 3.77065 sequence = AAAGTtGTtatACcAaTaT Gene: Ent638_2768: D-mannonate oxidoreductase (EC 1.1.1.57)	Erwinia amylovora ATCC 49946	* Yersinia pestis KIM Site: position = -91 score = 5.30161 sequence = AAACTGGTCTAACAACTTT Gene: y2903: D-mannonate oxidoreductase (EC 1.1.1.57)	* Serratia proteamaculans 568 Site: position = -64 score = 5.28364 sequence = AAACTGGTCTGATAACTTC Gene: Spro_3239: D-mannonate oxidoreductase (EC 1.1.1.57)	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA0819: D-mannonate oxidoreductase (EC 1.1.1.57)	* Edwardsiella tarda EIB202 Site: position = -89 score = 4.69588 sequence = CAAGTGGTCTAACACCTTT Gene: ETAE_2291: D-mannonate oxidoreductase (EC 1.1.1.57)	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu0175: D-mannonate oxidoreductase (EC 1.1.1.57)	D-mannonate oxidoreductase (EC 1.1.1.57)
uxuA	Escherichia coli str. K-12 substr. MG1655 Gene: b4322: Mannonate dehydratase (EC 4.2.1.8)	Salmonella typhimurium LT2 Gene: STM3135: Mannonate dehydratase (EC 4.2.1.8)	* Citrobacter koseri ATCC BAA-895 Site: position = -31 score = 5.33473 sequence = AATTTGGTATAACAACTTG Gene: CKO_00609: Mannonate dehydratase (EC 4.2.1.8)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -34 score = 5.46954 sequence = TTATTGGTATAACAACTTT Gene: KPN_02604: Mannonate dehydratase (EC 4.2.1.8)	* Enterobacter sp. 638 Site: position = -32 score = 5.66582 sequence = ATATTGGTATAACAACTTT Gene: Ent638_2767: Mannonate dehydratase (EC 4.2.1.8)	Erwinia amylovora ATCC 49946	* Yersinia pestis KIM Site: position = -240 score = 5.21248 sequence = AAATCGGTATAACAACATT Gene: y2902: Mannonate dehydratase (EC 4.2.1.8)	* Serratia proteamaculans 568 Site: position = -80 score = 5.01709 sequence = AATTTGGTATAACAAGATT Gene: Spro_3238: Mannonate dehydratase (EC 4.2.1.8)	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA1093: Mannonate dehydratase (EC 4.2.1.8)	* Edwardsiella tarda EIB202 Site: position = -101 score = 4.69694 sequence = GATTTGGTATGACAGATTA Gene: ETAE_2289: Mannonate dehydratase (EC 4.2.1.8)	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu0170: Mannonate dehydratase (EC 4.2.1.8)	Mannonate dehydratase (EC 4.2.1.8)

CRON 3.
uxaC	* Escherichia coli str. K-12 substr. MG1655 Site: position = -71 score = 6.21724 sequence = AAATTGGTGTGATAACTTT Gene: b3092: Uronate isomerase (EC 5.3.1.12)	Salmonella typhimurium LT2	* Citrobacter koseri ATCC BAA-895 Site: position = -8 score = 6.21724 sequence = AAATTGGTGTGATAACTTT Gene: CKO_04494: Uronate isomerase (EC 5.3.1.12)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -90 score = 6.21724 sequence = AAATTGGTGTGATAACTTT Gene: KPN_03520: Uronate isomerase (EC 5.3.1.12)	* Enterobacter sp. 638 Site: position = -70 score = 6.21724 sequence = AAATTGGTGTGATAACTTT Gene: Ent638_3546: Uronate isomerase (EC 5.3.1.12)	Erwinia amylovora ATCC 49946	* Yersinia pestis KIM Site: position = -69 score = 6.02096 sequence = TAATTGGTGTGATAACTTT Gene: y3600: Uronate isomerase (EC 5.3.1.12)	* Serratia proteamaculans 568 Site: position = -70 score = 6.21724 sequence = AAATTGGTGTGATAACTTT Gene: Spro_4321: Uronate isomerase (EC 5.3.1.12)	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -67 score = 5.44594 sequence = TAATTGGTGTGATATCTTT Gene: ECA0645: Uronate isomerase (EC 5.3.1.12)	* Edwardsiella tarda EIB202 Site: position = -69 score = 6.12696 sequence = AAATTGGTGTGATAACTTC Gene: ETAE_0436: Uronate isomerase (EC 5.3.1.12)	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Uronate isomerase (EC 5.3.1.12)
uxaB	* Escherichia coli str. K-12 substr. MG1655 Site: position = -33 score = 4.34816 sequence = CAGGTTGTATGACTAATCA Gene: b1521: Altronate oxidoreductase (EC 1.1.1.58)	Salmonella typhimurium LT2	* Citrobacter koseri ATCC BAA-895 Site: position = -34 score = 4.50182 sequence = CAGGTTGTATGACTAATTA Gene: CKO_01541: Altronate oxidoreductase (EC 1.1.1.58)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -34 score = 4.3098 sequence = CAGGTTGTATGACTACTAT Gene: KPN_01640: Altronate oxidoreductase (EC 1.1.1.58)	Enterobacter sp. 638 Gene: Ent638_2013: Altronate oxidoreductase (EC 1.1.1.58)	Erwinia amylovora ATCC 49946	Yersinia pestis KIM Gene: y3599: Altronate oxidoreductase (EC 1.1.1.58)	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA0646: Altronate oxidoreductase (EC 1.1.1.58)	Edwardsiella tarda EIB202 Gene: ETAE_0437: Altronate oxidoreductase (EC 1.1.1.58)	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Altronate oxidoreductase (EC 1.1.1.58)
uxaA	Escherichia coli str. K-12 substr. MG1655 Gene: b3091: Altronate hydrolase (EC 4.2.1.7)	Salmonella typhimurium LT2	Citrobacter koseri ATCC BAA-895 Gene: CKO_04493: Altronate hydrolase (EC 4.2.1.7)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_03519: Altronate hydrolase (EC 4.2.1.7)	Enterobacter sp. 638 Gene: Ent638_3545: Altronate hydrolase (EC 4.2.1.7)	Erwinia amylovora ATCC 49946	Yersinia pestis KIM Gene: y3598: Altronate hydrolase (EC 4.2.1.7)	Serratia proteamaculans 568 Gene: Spro_4320: Altronate hydrolase (EC 4.2.1.7)	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA0647: Altronate hydrolase (EC 4.2.1.7)	Edwardsiella tarda EIB202 Gene: ETAE_0438: Altronate hydrolase (EC 4.2.1.7)	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Altronate hydrolase (EC 4.2.1.7)

CRON 4.
lfaR	Escherichia coli str. K-12 substr. MG1655	Salmonella typhimurium LT2	* Citrobacter koseri ATCC BAA-895 Site: position = -157 score = 5.82167 sequence = TAAGTTGTGTGACAAGTTC Gene: CKO_02295: putative transcriptional regulator, LacI family	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -195 score = 4.53863 sequence = TCATTGGTATAACTAGTAT Gene: KPN_00854: putative transcriptional regulator, LacI family	* Enterobacter sp. 638 Site: position = -175 score = 5.59941 sequence = GAAGTTGTGTGACAAGTTC Gene: Ent638_1314: putative transcriptional regulator, LacI family	Erwinia amylovora ATCC 49946	Yersinia pestis KIM Gene: y3231: putative transcriptional regulator, LacI family	* Serratia proteamaculans 568 Site: position = -196 score = 4.83135 sequence = TAATTGGACTGATAAATCT Gene: Spro_3600: putative transcriptional regulator, LacI family	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -176 score = 4.77789 sequence = AAATTGGTTTACCAAATTG Gene: ECA1966: putative transcriptional regulator, LacI family	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	putative transcriptional regulator, LacI family

CRON 5.
exuT	* Escherichia coli str. K-12 substr. MG1655 Site: position = -129 score = 6.15906 sequence = AAAGTTGTATGACAAGTTA Gene: b3093: Hexuronate transporter	Salmonella typhimurium LT2	* Citrobacter koseri ATCC BAA-895 Site: position = -227 score = 5.74052 sequence = GAAGTTGTATGACAAGTTA Gene: CKO_04495: Hexuronate transporter	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -240 score = 6.15906 sequence = AAAGTTGTATGACAAGTTA Gene: KPN_03521: Hexuronate transporter	* Enterobacter sp. 638 Site: position = -116 score = 6.15906 sequence = AAAGTTGTATGACAAGTTA Gene: Ent638_3547: Hexuronate transporter	Erwinia amylovora ATCC 49946	* Yersinia pestis KIM Site: position = -515 score = 5.62807 sequence = AAAtctGTATGACAAgTTa Gene: y3601: Hexuronate transporter	* Serratia proteamaculans 568 Site: position = -157 score = 5.62807 sequence = AAATCTGTATGACAAGTTA Gene: Spro_4322: Hexuronate transporter	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -185 score = 6.18769 sequence = AAAGTTGTATGACAAATTA Gene: ECA0644: Hexuronate transporter	* Edwardsiella tarda EIB202 Site: position = -282 score = 5.20953 sequence = GAATCTGTATGACAAGTTA Gene: ETAE_0435: Hexuronate transporter	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Hexuronate transporter

CRON 6.
lfaT	Escherichia coli str. K-12 substr. MG1655	Salmonella typhimurium LT2	* Citrobacter koseri ATCC BAA-895 Site: position = -59 score = 4.62699 sequence = AAATTTGTGTGACACCAAA Gene: CKO_02296: Putative MFS superfamily hexuronate transporter	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_00853: Putative MFS superfamily hexuronate transporter	* Enterobacter sp. 638 Site: position = -60 score = 4.44009 sequence = TAATCTGTGTGACAACCGA Gene: Ent638_1313: Putative MFS superfamily hexuronate transporter	Erwinia amylovora ATCC 49946	Yersinia pestis KIM Gene: y3232: Putative MFS superfamily hexuronate transporter	* Serratia proteamaculans 568 Site: position = -209 score = 5.24728 sequence = GAATTGGTATACCAACTTT Gene: Spro_3599: Putative MFS superfamily hexuronate transporter	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA1967: Putative MFS superfamily hexuronate transporter	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Putative MFS superfamily hexuronate transporter
lfaA	Escherichia coli str. K-12 substr. MG1655	Salmonella typhimurium LT2	Citrobacter koseri ATCC BAA-895 Gene: CKO_02297: Alpha-glucosidase (EC 3.2.1.20)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_00852: Alpha-glucosidase (EC 3.2.1.20)	Enterobacter sp. 638 Gene: Ent638_1312: Alpha-glucosidase (EC 3.2.1.20)	Erwinia amylovora ATCC 49946	Yersinia pestis KIM Gene: y3233: Alpha-glucosidase (EC 3.2.1.20)	Serratia proteamaculans 568 Gene: Spro_3598: Alpha-glucosidase (EC 3.2.1.20)	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA1968: Alpha-glucosidase (EC 3.2.1.20)	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Alpha-glucosidase (EC 3.2.1.20)

CRON 7.
gntP	Escherichia coli str. K-12 substr. MG1655 Gene: b4321: Fructuronate transporter GntP	Salmonella typhimurium LT2	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Yersinia pestis KIM Gene: y3426: Fructuronate transporter GntP	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	* Edwardsiella tarda EIB202 Site: position = -93 score = 5.32539 sequence = AAAGTGGTGTGATAACCGT Gene: ETAE_1036: Fructuronate transporter GntP	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Fructuronate transporter GntP

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog ExuR - Enterobacteriales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --