Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of RegR regulog to Streptococcus pyogenes MGAS9429

Reference regulog properties
Source regulog: RegR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: LacI
Regulation mode: repressor
Biological process: Hyaluronate utilization
Effector: Hyaluronate oligosaccharide phosphate
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pyogenes MGAS9429
Orthologous TF(s) MGAS9429_Spy0508
Regulated genes 3
Built upon 27 sites [see more]
Predicted regulatory interactions in Streptococcus pyogenes MGAS9429
Locus tag Position Score Sequence
Position: -299
Score: 6.3
Sequence: TAAGTAAACCTGTTTACTAA
Position: -270
Score: 5.1
Sequence: AAAGTAAACTAGTTTTGTCA
Position: -33
Score: 5
Sequence: TGAGTAAACCGGTAAACCAA
Locus tag: MGAS9429_Spy0514
MGAS9429_Spy0514 -299 6.3 TAAGTAAACCTGTTTACTAA
-270 5.1 AAAGTAAACTAGTTTTGTCA
-33 5 TGAGTAAACCGGTAAACCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: hylD
Ortholog function: PTS system, hyaluronate-oligosaccharide-specific IIA component (EC 2.7.1.69)
Streptococcus agalactiae 2603V/R SAG1902 -251 5.1 GAAGTAAACCTGTTTACATG
-222 5.9 AAAGTAAACCGGTTTTGTCA
-32 5.1 AAAGTAAACCGGTAAACTCA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0648 -280 5.1 AAAGTAAACTAGTTTTGTCA
-33 5.3 TAAGTAAACCGGTAAACTAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1304 -281 6.1 TAAGTAAACCTGTTTACCAA
-33 5.3 TAAGTAAACCGGTAAACTAA
Streptococcus pneumoniae TIGR4 SP_0321 -219 5.6 CTAGTAAACCGGTTTTGTCA
-37 5 AAAGTAAACCGGTAAACCTA
Streptococcus pyogenes M1 GAS SPy0634 -281 5.1 AAAGTAAACTAGTTTTGTCA
-33 4.6 TGAGTAAACCGGTAAACCGA
Streptococcus suis 05ZYH33 SSU05_1221 -33 4.9 TAGGTAAACCGGTAAAGTTA
Position: -45
Score: 6.3
Sequence: TTAGTAAACAGGTTTACTTA
Locus tag: MGAS9429_Spy0515
MGAS9429_Spy0515 -45 6.3 TTAGTAAACAGGTTTACTTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: kduD
Ortholog function: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127)
Streptococcus agalactiae 2603V/R SAG1904 -265 5.1 TGAGTTTACCGGTTTACTTT
-75 5.9 TGACAAAACCGGTTTACTTT
-46 5.1 CATGTAAACAGGTTTACTTC
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0650 -74 5.1 TGACAAAACTAGTTTACTTT
-45 6.1 TTGGTAAACAGGTTTACTTA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1303 -293 5.3 TTAGTTTACCGGTTTACTTA
-45 6.1 TTGGTAAACAGGTTTACTTA
Streptococcus pneumoniae TIGR4 SP_0320 -253 5 TAGGTTTACCGGTTTACTTT
-71 5.6 TGACAAAACCGGTTTACTAG
Streptococcus pyogenes M1 GAS SPy0636 -74 5.1 TGACAAAACTAGTTTACTTT
-45 6.1 TTGGTAAACAGGTTTACTTA
Streptococcus suis 05ZYH33 SSU05_1225 -75 5.8 TGACAAAACCGGTTTACTAT
Position: 15
Score: 5.1
Sequence: TTAGTAAACCAATCTACTTT
Locus tag: MGAS9429_Spy0871
MGAS9429_Spy0871 15 5.1 TTAGTAAACCAATCTACTTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: hyl
Ortholog function: Hyaluronate lyase precursor (EC 4.2.2.1)
Streptococcus agalactiae 2603V/R SAG1197 -42 5 AGGAAAAACCGGTTTACAAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0654 -74 5.1 TGACAAAACTAGTTTACTTT
-45 6.1 TTGGTAAACAGGTTTACTTA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1299 -293 5.3 TTAGTTTACCGGTTTACTTA
-45 6.1 TTGGTAAACAGGTTTACTTA
Streptococcus pneumoniae TIGR4 SP_0314 -89 6.2 TAATTAAACCGGTTTACTTA
Streptococcus pyogenes M1 GAS SPy1032 -54 5.5 TTAGTAAATCAATTTACTTT
Streptococcus suis 05ZYH33 SSU05_1215 -33 4.9 TAGGTAAACCGGTAAAGTTA
Streptococcus suis 05ZYH33 SSU05_1214 -33 4.9 TAGGTAAACCGGTAAAGTTA
Streptococcus suis 05ZYH33 SSU05_1213 -33 4.9 TAGGTAAACCGGTAAAGTTA
Streptococcus suis 05ZYH33 SSU05_1212 -33 4.9 TAGGTAAACCGGTAAAGTTA