Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing hypN gene

Properties
Regulog: HypR - Rhodobacterales
Regulator type: Transcription factor
Regulator family: GntR/Others
Regulation mode: activator (repressor)
Biological process: Proline and 4-hydrohyproline utilization
Effector: 4-hydroxyproline
Phylum: Proteobacteria/alpha
Built upon 10 sites [see more]
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Paracoccus denitrificans PD1222
Position: -111
Score: 3.53292
Sequence: TTTTGTATATTAGT
Position: -94
Score: 3.99007
Sequence: TTTTGCATACATGA
Locus tag: Pden_4865
Name: hypH
Funciton: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible
Locus tag: Pden_4864
Name: hypM
Funciton: Predicted hydroxyproline ABC transporter, substrate-binding protein
Locus tag: Pden_4863
Name: hypN
Funciton: Predicted hydroxyproline ABC transporter, permease protein
Locus tag: Pden_4862
Name: hypP
Funciton: Predicted hydroxyproline ABC transporter, permease protein
Locus tag: Pden_4861
Name: hypQ
Funciton: Predicted hydroxyproline ABC transporter, ATP-binding protein
Locus tag: Pden_4860
Name: hypO
Funciton: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster
Locus tag: Pden_4859
Name: hypE
Funciton: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
Locus tag: Pden_4858
Name: hypA
Funciton: Predicted hydroxyproline TRAP-type transport system, small permease component
Locus tag: Pden_4857
Name: hypB
Funciton: Predicted hydroxyproline TRAP-type transport system, large permease component
Locus tag: Pden_4856
Name: hypC
Funciton: Predicted hydroxyproline TRAP-type transport system, periplasmic component
Locus tag: Pden_4855
Name: hypS
Funciton: Putative L-lactate/Malate dehydrogenase
Locus tag: Pden_4854
Name: hypX
Funciton: Putative citrate/isocitrate isomerase or aconitase ## predicted from clustering to proline racemase
hypH-hypM-hypN-hypP-hypQ-hypO-hypE-hypA-hypB-hypC-hypS-hypX -111 3.5 TTTTGTATATTAGT Pden_4865
-94 4 TTTTGCATACATGA