Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of ThiR in Thermococcus sibiricus MM 739

Properties
Regulator type: Transcription factor
TF locus tag: TSIB_0198
Regulator family: [Other]
Regulation mode: repressor
Biological process: Thiamine transport; Thiamine biosynthesis
Effector: Thiamine phosphate
Regulog: ThiR - Thermococcales
Statistics of regulated genes:
- Genes 10
- Operons 3
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 35 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -70
Score: 5.1
Sequence: ATAACTTGGTTTT
Locus tag: TSIB_0467
Name: cytX
Funciton: Hydroxymethylpyrimidine transporter CytX
Locus tag: TSIB_0466
Name: tenA1
Funciton: Thiaminase II (EC 3.5.99.2)
Locus tag: TSIB_0465
Name: thiM
Funciton: Hydroxyethylthiazole kinase (EC 2.7.1.50)
Locus tag: TSIB_0464
Name: thiE
Funciton: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
Locus tag: TSIB_0463
Name: thiW
Funciton: Thiazole transporter ThiW
Locus tag: TSIB_0462
Name: thiDN
Funciton: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
cytX
Hydroxymethylpyrimidine transporter CytX
tenA1
Thiaminase II (EC 3.5.99.2)
thiM
Hydroxyethylthiazole kinase (EC 2.7.1.50)
thiE
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
thiW
Thiazole transporter ThiW
thiDN
Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)

Position: -37
Score: 5.2
Sequence: ATAACTGAGTTTT
Locus tag: TSIB_0198
Name: thiR
Funciton: Thiamin-phosphate synthase-like transcriptional regulator ThiR
Locus tag: TSIB_0199
Name: null
Funciton: hypothetical protein
Locus tag: TSIB_0200
Name: yjbQ
Funciton: YjbQ (alternate ThiE)
thiR
Thiamin-phosphate synthase-like transcriptional regulator ThiR
hypothetical protein
yjbQ
YjbQ (alternate ThiE)

Position: -36
Score: 4.5
Sequence: AGAACAGAGTTAT
Position: -15
Score: 4.9
Sequence: AAAAATTAGTTTT
Locus tag: TSIB_0369
Name: thiB
Funciton: Thiamin ABC transporter, substrate-binding component
thiB
Thiamin ABC transporter, substrate-binding component
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