Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of CcpA in Staphylococcus aureus subsp. aureus N315

Properties
Regulator type: Transcription factor
TF locus tag: SA1557
Regulator family: LacI
Regulation mode: repressor (activator)
Biological process: Carbon catabolism
Effector: HPr, phosphocarrier protein; Fructose-1,6-diphosphate
Regulog: CcpA - Staphylococcaceae
Statistics of regulated genes:
- Genes 124
- Operons 73
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 391 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -71
Score: 4.6
Sequence: AATAAAACGTTTACAA
Locus tag: SA1557
Name: ccpA
Funciton: catabolite control protein A
ccpA
catabolite control protein A

Position: -51
Score: 4.3
Sequence: TGGTAAGCGCATACAT
Locus tag: SA1968
Name: arg
Funciton: arginase
arg
arginase

Position: -62
Score: 4
Sequence: ATGtAAGCGtTTgaAg
Locus tag: SA2428
Name: arcA
Funciton: arginine deiminase
Locus tag: SA2427
Name: arcB
Funciton: ornithine carbamoyltransferase
Locus tag: SA2426
Name: arcD
Funciton: arginine/ornithine antiporter
Locus tag: SA2425
Name: arcC
Funciton: carbamate kinase
Locus tag: SA2424
Name: arcR
Funciton: transcription regulator of arginine catabolism, Crp/Fnr family
arcA
arginine deiminase
arcB
ornithine carbamoyltransferase
arcD
arginine/ornithine antiporter
arcC
carbamate kinase
arcR
transcription regulator of arginine catabolism, Crp/Fnr family

Position: -53
Score: 4.7
Sequence: AAGAAAACGCTTGCAA
Locus tag: SA0510
Name: araB
Funciton: putative L-ribulokinase
araB
putative L-ribulokinase

Position: -103
Score: 5
Sequence: ATGTAAACGCTTACTA
Locus tag: SA0162
Name: aldA
Funciton: aldehyde dehydrogenase
aldA
aldehyde dehydrogenase

Position: -52
Score: 4.5
Sequence: TTGATTGCGCTTTCAA
Locus tag: SA1531
Name: ald
Funciton: alanine dehydrogenase
ald
alanine dehydrogenase

Position: -147
Score: 4.7
Sequence: GTGAAAACGCTTTCTT
Locus tag: SA1555
Name: acuA
Funciton: acetoin utilization protein AcuA
Locus tag: SA1556
Name: acuC
Funciton: acetoin utilization protein AcuC
acuA
acetoin utilization protein AcuA
acuC
acetoin utilization protein AcuC

Position: -37
Score: 4.7
Sequence: AAGAAAGCGTTTTCAC
Locus tag: SA1554
Name: acsA
Funciton: acetyl-CoA synthetase
acsA
acetyl-CoA synthetase

Position: -54
Score: 4.7
Sequence: AAGAAAACGCTTACAC
Locus tag: SA2226
Name: aapA
Funciton: D-serine/D-alanine/glycine transporter
Locus tag: SA2227
Name: aapA
Funciton: D-serine/D-alanine/glycine transporter
aapA
D-serine/D-alanine/glycine transporter
aapA
D-serine/D-alanine/glycine transporter

Position: -57
Score: 4.9
Sequence: ATGTAAGCGTTTTAAA
Locus tag: SA2122
Name: hutU
Funciton: urocanate hydratase
Locus tag: SA2121
Name: hutI
Funciton: imidazolonepropionase
hutU
urocanate hydratase
hutI
imidazolonepropionase

Position: -59
Score: 4.6
Sequence: ATGAAAACGTATACTT
Locus tag: SA0008
Name: hutH
Funciton: histidine ammonia-lyase
hutH
histidine ammonia-lyase

Position: -334
Score: 4.8
Sequence: TTGTAATCGATTACAT
Locus tag: SA1007
Name: hla
Funciton: Alpha-Hemolysin
hla
Alpha-Hemolysin

Position: -148
Score: 4.7
Sequence: TTGTAAACGCTTTCCA
Locus tag: SA2300
Name: gudP
Funciton: glucarate transporter
gudP
glucarate transporter

Position: -84
Score: 4.5
Sequence: TTGTAAGGGCTTTAAA
Position: -42
Score: 4.3
Sequence: TTGAAAGCGAAATCAT
Locus tag: SA0819
Name: gudB
Funciton: NAD-specific glutamate dehydrogenase
gudB
NAD-specific glutamate dehydrogenase

Position: -79
Score: 4.7
Sequence: AAGAAAGCGCTTGCAA
Locus tag: SA2295
Name: gntR
Funciton: gluconate operon transcriptional repressor
Locus tag: SA2294
Name: gntK
Funciton: gluconokinase
Locus tag: SA2293
Name: gntP
Funciton: gluconate permease
gntR
gluconate operon transcriptional repressor
gntK
gluconokinase
gntP
gluconate permease

Position: -241
Score: 4.7
Sequence: TAGTAAACGCTTACAC
Locus tag: SA2115
Name: glvR
Funciton: transcriptional regulator of maltose utilization, RpiR family
glvR
transcriptional regulator of maltose utilization, RpiR family

Position: -104
Score: 4.7
Sequence: GTGTAAGCGTTTACTA
Locus tag: SA2114
Name: glvC
Funciton: maltose-specific enzyme IICB of PTS system
glvC
maltose-specific enzyme IICB of PTS system

Position: -64
Score: 4.5
Sequence: TTTATAACGCTTACAT
Locus tag: SA2135
Name: gltS
Funciton: sodium/glutamate symporter
gltS
sodium/glutamate symporter

Position: -76
Score: 4.8
Sequence: TTGACAACGCTTTCAT
Locus tag: SA0325
Name: glpT
Funciton: glycerol-3-phosphate transporter
glpT
glycerol-3-phosphate transporter

Position: -133
Score: 4.8
Sequence: TTGACAACGCTTTCAT
Locus tag: SA1140
Name: glpF
Funciton: glycerol uptake facilitator
Locus tag: SA1141
Name: glpK
Funciton: glycerol kinase
Locus tag: SA1142
Name: glpD
Funciton: aerobic glycerol-3-phosphate dehydrogenase
glpF
glycerol uptake facilitator
glpK
glycerol kinase
glpD
aerobic glycerol-3-phosphate dehydrogenase

Position: -269
Score: 4.6
Sequence: TTGAAAACGCATACTT
Locus tag: SA0183
Name: glcA
Funciton: glucose-specific PTS enzyme IIABC
glcA
glucose-specific PTS enzyme IIABC

Position: -43
Score: 4
Sequence: GTGAAAGCGTACTCAT
Locus tag: SA0653
Name: fruR
Funciton: transcription repressor of fructose operon, DeoR family
Locus tag: SA0654
Name: fruB
Funciton: fructose 1-phosphate kinase
Locus tag: SA0655
Name: fruA
Funciton: PTS system fructose-specific IIABC component
fruR
transcription repressor of fructose operon, DeoR family
fruB
fructose 1-phosphate kinase
fruA
PTS system fructose-specific IIABC component

Position: -130
Score: 4.1
Sequence: ATGAAAGCGCTAACCC
Locus tag: SA1553
Name: fhs
Funciton: formyltetrahydrofolate synthetase
fhs
formyltetrahydrofolate synthetase

Position: -83
Score: 4.7
Sequence: ATGTTAACGTTTTCTT
Locus tag: SA2304
Name: fbp
Funciton: fructose-bisphosphatase
fbp
fructose-bisphosphatase

Position: -142
Score: 4.5
Sequence: ATGTATACGTTTGCAT
Locus tag: SA1927
Name: fbaA
Funciton: fructose-bisphosphate aldolase
fbaA
fructose-bisphosphate aldolase

Position: -64
Score: 4.6
Sequence: TTGTAAGGGTTTACAC
Locus tag: SA0227
Name: fadX
Funciton: putative acetyl-CoA transferase
Locus tag: SA0226
Name: fadE
Funciton: putative acyl-CoA synthetase
fadX
putative acetyl-CoA transferase
fadE
putative acyl-CoA synthetase

Position: -38
Score: 5.2
Sequence: TTGTAAACGTTTACAA
Locus tag: SA1633
Name: SA1633
Funciton: beta-lactamase
SA1633
beta-lactamase

Position: -84
Score: 4.6
Sequence: ATGAAACCGTTATCAT
Locus tag: SA2480
Name: drp35
Funciton: lactonase Drp35
drp35
lactonase Drp35

Position: -115
Score: 4.6
Sequence: ATGTATGCGGTTACAT
Locus tag: SA1939
Name: dra2
Funciton: deoxyribose-phosphate aldolase paralog
dra2
deoxyribose-phosphate aldolase paralog

Position: -64
Score: 4.6
Sequence: ATGATAGCGCATTCAT
Locus tag: SA0605
Name: dhaK
Funciton: dihydroxyacetone kinase, DhaK subunit
Locus tag: SA0606
Name: dhaL
Funciton: dihydroxyacetone kinase, DhaL subunit
Locus tag: SA0607
Name: SA0607
Funciton: hypothetical protein
dhaK
dihydroxyacetone kinase, DhaK subunit
dhaL
dihydroxyacetone kinase, DhaL subunit
SA0607
hypothetical protein

Position: -43
Score: 4.7
Sequence: TTGAAAGCCATTTCAT
Locus tag: SA1518
Name: citZ
Funciton: citrate synthase
Locus tag: SA1517
Name: citC
Funciton: isocitrate dehydrogenase
citZ
citrate synthase
citC
isocitrate dehydrogenase

Position: -103
Score: 4.4
Sequence: AATTAAGCGTTTTCTA
Locus tag: SA1184
Name: citB
Funciton: aconitate hydratase
citB
aconitate hydratase

Position: -63
Score: 4.8
Sequence: ATGTAAGCGATTACAC
Locus tag: SA0184
Name: SA0184
Funciton: hypothetical protein
Locus tag: SA0185
Name: murQ
Funciton: N-acetylmuramic acid 6-phosphate etherase
Locus tag: SA0186
Name: murT
Funciton: predicted N-acetylmuramate PTS system, IIBC components
Locus tag: SA0187
Name: murR
Funciton: predicted N-acetylmuramate-6-phosphate-responsive transcriptional regulator, RpiR family
SA0184
hypothetical protein
murQ
N-acetylmuramic acid 6-phosphate etherase
murT
predicted N-acetylmuramate PTS system, IIBC components
murR
predicted N-acetylmuramate-6-phosphate-responsive transcriptional regulator, RpiR family

Position: -150
Score: 4.9
Sequence: ATGTAAGGGTTTTCAA
Locus tag: SA0818
Name: rocD
Funciton: ornithine aminotransferase
rocD
ornithine aminotransferase

Position: -112
Score: 4.7
Sequence: ATGAAAGCGATTGCAA
Locus tag: SA2341
Name: rocA
Funciton: 1-pyrroline-5-carboxylate dehydrogenase
rocA
1-pyrroline-5-carboxylate dehydrogenase

Position: -86
Score: 4.6
Sequence: ATGAAAACGCATGCAT
Locus tag: SA0260
Name: rbsU
Funciton: ribose transporter RbsU
Locus tag: SA0259
Name: rbsD
Funciton: ribose permease
Locus tag: SA0258
Name: rbsK
Funciton: ribokinase
rbsU
ribose transporter RbsU
rbsD
ribose permease
rbsK
ribokinase

Position: -137
Score: 4.1
Sequence: ACGAAAGCGCTTCCTA
Locus tag: SA1718
Name: putP
Funciton: high affinity proline permease
putP
high affinity proline permease

Position: -71
Score: 4.7
Sequence: ATGAAAACGCTTTCTC
Locus tag: SA1585
Name: putA
Funciton: proline dehydrogenase
putA
proline dehydrogenase

Position: -76
Score: 5
Sequence: TTGAAAACGTTTTCTT
Locus tag: SA2320
Name: pfoR
Funciton: putative PTS transporter
Locus tag: SA2319
Name: sdaAB
Funciton: L-serine dehydratase beta chain
Locus tag: SA2318
Name: sdaAA
Funciton: L-serine dehydratase alpha chain
pfoR
putative PTS transporter
sdaAB
L-serine dehydratase beta chain
sdaAA
L-serine dehydratase alpha chain

Position: -59
Score: 4.9
Sequence: ATGAAAACGTTAACAT
Locus tag: SA0218
Name: pflB
Funciton: Pyruvate formate lyase
Locus tag: SA0219
Name: pflA
Funciton: Pyruvate formate lyase activating enzyme
pflB
Pyruvate formate lyase
pflA
Pyruvate formate lyase activating enzyme

Position: -151
Score: 4.8
Sequence: TTTAAAACGTTTACAT
Locus tag: SA1521
Name: pfkA
Funciton: 6-phosphofructokinase
Locus tag: SA1520
Name: pykA
Funciton: pyruvate kinase
pfkA
6-phosphofructokinase
pykA
pyruvate kinase

Position: -44
Score: 5
Sequence: ATGTAAAGGCTTACAT
Locus tag: SA1609
Name: pckA
Funciton: phosphoenolpyruvate carboxykinase
pckA
phosphoenolpyruvate carboxykinase

Position: -63
Score: 4.4
Sequence: ATGTTAGCCCTTCCAT
Locus tag: SA0479
Name: nupC
Funciton: pyrimidine nucleoside transporter
nupC
pyrimidine nucleoside transporter

Position: -109
Score: 4.9
Sequence: TTGTAAACGCTATCAT
Locus tag: SA0305
Name: nanK
Funciton: predicted N-acetyl-D-mannosamine kinase, ROK family
nanK
predicted N-acetyl-D-mannosamine kinase, ROK family

Position: -64
Score: 4.9
Sequence: ATGATAGCGTTTACAA
Locus tag: SA0304
Name: nanA
Funciton: N-acetylneuraminate lyase
Locus tag: SA0303
Name: nanT
Funciton: predicted sialic acid transporter
nanA
N-acetylneuraminate lyase
nanT
predicted sialic acid transporter

Position: -123
Score: 4.9
Sequence: ATTAAAACGCTTACAA
Locus tag: SA2334
Name: mvaS
Funciton: 3-hydroxy-3-methylglutaryl CoA synthase
mvaS
3-hydroxy-3-methylglutaryl CoA synthase

Position: -147
Score: 4.9
Sequence: TTGTAAGCGTTTTAAT
Locus tag: SA2333
Name: mvaA
Funciton: hydroxymethylglutaryl-CoA reductase
mvaA
hydroxymethylglutaryl-CoA reductase

Position: -45
Score: 4.2
Sequence: TTAAAAACGCTTACAC
Locus tag: SA2433
Name: manR
Funciton: antiterminator for mannose operon, BglG family
manR
antiterminator for mannose operon, BglG family

Position: -37
Score: 4.3
Sequence: GAGAATACGCTTACAA
Locus tag: SA2434
Name: manP
Funciton: PTS system mannose-specific EIIBCA component
Locus tag: SA2435
Name: manA
Funciton: mannose-6-phosphate isomerase
manP
PTS system mannose-specific EIIBCA component
manA
mannose-6-phosphate isomerase

Position: -130
Score: 5.2
Sequence: ATGTAAACGTTTACAA
Locus tag: SA0206
Name: msmX
Funciton: putative maltodexrtrin ABC transporter, ATP-binding protein
Locus tag: SA0207
Name: mdxE
Funciton: putative maltodexrtrin ABC transporter, substrate-binding protein
Locus tag: SA0208
Name: mdxF
Funciton: putative maltodexrtrin ABC transporter, permease protein 1
Locus tag: SA0209
Name: mdxG
Funciton: putative maltodexrtrin ABC transporter, permease protein 2
Locus tag: SA0210
Name: gfoA
Funciton: putative glucose dehydrogenase A
Locus tag: SA0211
Name: gfoB
Funciton: putative glucose dehydrogenase B
Locus tag: SA0212
Name: gfoI
Funciton: putative sugar isomerase
msmX
putative maltodexrtrin ABC transporter, ATP-binding protein
mdxE
putative maltodexrtrin ABC transporter, substrate-binding protein
mdxF
putative maltodexrtrin ABC transporter, permease protein 1
mdxG
putative maltodexrtrin ABC transporter, permease protein 2
gfoA
putative glucose dehydrogenase A
gfoB
putative glucose dehydrogenase B
gfoI
putative sugar isomerase

Position: -43
Score: 4.4
Sequence: TTGGAAGCGTTTTCCA
Locus tag: SA1339
Name: malR
Funciton: maltose operon transcriptional repressor
Locus tag: SA1338
Name: malA
Funciton: alpha-D-1,4-glucosidase
malR
maltose operon transcriptional repressor
malA
alpha-D-1,4-glucosidase

Position: -137
Score: 4.7
Sequence: ATGTAAACGCTTTCTC
Locus tag: SA2463
Name: lip
Funciton: triacylglycerol lipase precursor
lip
triacylglycerol lipase precursor

Position: -79
Score: 4.6
Sequence: ATGATAAGGCTTTCAA
Locus tag: SA0508
Name: kbl
Funciton: 2-amino-3-ketobutyrate coenzyme A ligase
kbl
2-amino-3-ketobutyrate coenzyme A ligase

Position: -97
Score: 4.6
Sequence: TTGTTAGCGTTTTCAC
Locus tag: SA0182
Name: ipdC
Funciton: indole-3-pyruvate decarboxylase homolog
ipdC
indole-3-pyruvate decarboxylase homolog

Position: -68
Score: 4.9
Sequence: TTGAAAGCCTTTACAT
Locus tag: SA0432
Name: treP
Funciton: phosphotransferase system trehalose-specific enzyme IIBC component homolog
Locus tag: SA0433
Name: treA
Funciton: trehalose-6-phosphate hydrolase
Locus tag: SA0434
Name: treR
Funciton: trehalose-6-phosphate-responsive transcriptional regulator
treP
phosphotransferase system trehalose-specific enzyme IIBC component homolog
treA
trehalose-6-phosphate hydrolase
treR
trehalose-6-phosphate-responsive transcriptional regulator

Position: -237
Score: 4.6
Sequence: ATTAAACCGCTTTCAT
Locus tag: SA0107
Name: spa
Funciton: Immunoglobulin G binding protein A precursor
spa
Immunoglobulin G binding protein A precursor

Position: -235
Score: 4.4
Sequence: GTGGAAGCGTTTTCTA
Locus tag: SA0994
Name: sdhC
Funciton: succinate dehydrogenase cytochrome b subunit
Locus tag: SA0995
Name: sdhA
Funciton: succinate dehydrogenase flavoprotein subunit
Locus tag: SA0996
Name: sdhB
Funciton: succinate dehydrogenase iron-sulfur protein subunit
sdhC
succinate dehydrogenase cytochrome b subunit
sdhA
succinate dehydrogenase flavoprotein subunit
sdhB
succinate dehydrogenase iron-sulfur protein subunit

Position: -162
Score: 4.9
Sequence: TTGAAAGCGCATTCAT
Locus tag: SA1732
Name: sdcS
Funciton: sodium-dependent dicarboxylate transporter
sdcS
sodium-dependent dicarboxylate transporter

Position: -65
Score: 4.3
Sequence: TTTAAAGCGGTTACAC
Locus tag: SA1847
Name: scrR
Funciton: sucrose operon repressor
scrR
sucrose operon repressor

Position: -127
Score: 4.6
Sequence: ATGAATGCGCTATCAA
Position: -61
Score: 4.4
Sequence: TTGGAACCGGTTACAA
Locus tag: SA2167
Name: scrA
Funciton: PTS system, sucrose-specific IIBC component
scrA
PTS system, sucrose-specific IIBC component

Position: -64
Score: 5
Sequence: TTGAAAACGATTACAA
Locus tag: SAS074
Name: SAS074
Funciton: hypothetical protein
SAS074
hypothetical protein

Position: -122
Score: 4.2
Sequence: CTGTAAACGATTGCAT
Locus tag: SA2109
Name: SA2109
Funciton: probable amino-acid or metabolite transporter
SA2109
probable amino-acid or metabolite transporter

Position: -117
Score: 4.7
Sequence: ATGTAAGCGTTTTCCA
Locus tag: SA2105
Name: SA2105
Funciton: hypothetical protein
SA2105
hypothetical protein

Position: -128
Score: 5
Sequence: TTGTAATCGTTTTCAA
Locus tag: SA1975
Name: SA1975
Funciton: predicted membrane-bound hydrolase
Locus tag: SA1974
Name: SA1974
Funciton: UDP-N-acetylglucosamine pyrophosphorylase
Locus tag: SA1973
Name: SA1973
Funciton: hemolysin III
SA1975
predicted membrane-bound hydrolase
SA1974
UDP-N-acetylglucosamine pyrophosphorylase
SA1973
hemolysin III

Position: -50
Score: 4.5
Sequence: ATGAAAAGGTATTCAA
Locus tag: SA1437
Name: SA1437
Funciton: allophanate hydrolase subunit 1
Locus tag: SA1436
Name: SA1436
Funciton: allophanate hydrolase subunit 2
Locus tag: SA1435
Name: SA1435
Funciton: acetyl-CoA carboxylase (biotin carboxyl carrier subunit)
Locus tag: SA1434
Name: SA1434
Funciton: acetyl-CoA carboxylase (biotin carboxylase subunit)
Locus tag: SA1433
Name: SA1433
Funciton: putative lactame utilization protein
Locus tag: SA1432
Name: SA1432
Funciton: putative transporter
SA1437
allophanate hydrolase subunit 1
SA1436
allophanate hydrolase subunit 2
SA1435
acetyl-CoA carboxylase (biotin carboxyl carrier subunit)
SA1434
acetyl-CoA carboxylase (biotin carboxylase subunit)
SA1433
putative lactame utilization protein
SA1432
putative transporter

Position: -27
Score: 4.4
Sequence: GTGAAAGCGCTTGCTT
Locus tag: SA1162
Name: SA1162
Funciton: hypothetical protein
SA1162
hypothetical protein

Position: -62
Score: 4.6
Sequence: ATGTAACGGTTTTCAA
Locus tag: SA0873
Name: SA0873
Funciton: DJ-1/PfpI family protein
SA0873
DJ-1/PfpI family protein

Position: -97
Score: 4.4
Sequence: AAGAAAGCGCTTTTAT
Locus tag: SA0511
Name: SA0511
Funciton: uncharacterized epimerase/dehydratase
SA0511
uncharacterized epimerase/dehydratase

Position: -93
Score: 5.3
Sequence: ATGTAAGCGTTTACAA
Locus tag: SA0299
Name: SA0299
Funciton: hypothetical protein
Locus tag: SA0300
Name: SA0300
Funciton: hypothetical protein
Locus tag: SA0301
Name: SA0301
Funciton: hypothetical protein
Locus tag: SA0302
Name: nupC2
Funciton: probable pyrimidine nucleoside transport protein
SA0299
hypothetical protein
SA0300
hypothetical protein
SA0301
hypothetical protein
nupC2
probable pyrimidine nucleoside transport protein

Position: -86
Score: 4.9
Sequence: GTGTAAGCGTTTACAA
Locus tag: SA0225
Name: SA0225
Funciton: short-chain acyl-CoA oxidase
Locus tag: SA0224
Name: fadN
Funciton: putative 3-hydroxyacyl-CoA dehydrogenase
Locus tag: SA0223
Name: fadA
Funciton: putative acetyl-CoA acetyltransferase
SA0225
short-chain acyl-CoA oxidase
fadN
putative 3-hydroxyacyl-CoA dehydrogenase
fadA
putative acetyl-CoA acetyltransferase

Position: -152
Score: 5
Sequence: ATGTAAACGTTTACTA
Locus tag: SA0760
Name: yusH
Funciton: hypothetical protein
yusH
hypothetical protein

Position: -61
Score: 4.3
Sequence: TATTAAGCGCTTACAC
Locus tag: SA0214
Name: uhpT
Funciton: hexose phosphate transport protein
uhpT
hexose phosphate transport protein

Position: -39
Score: 4.9
Sequence: ATGTAAACGTTTACAC
Locus tag: SA1819
Name: tst
Funciton: toxic shock syndrome toxin-1
tst
toxic shock syndrome toxin-1
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