Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of Rex in Streptomyces avermitilis MA-4680

Properties
Regulator type: Transcription factor
TF locus tag: SAV_4738
Regulator family: Rex
Regulation mode: repressor
Biological process: Energy metabolism
Effector: NADH
Regulog: Rex - Streptomycetaceae
Statistics of regulated genes:
- Genes 39
- Operons 9
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 36 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -60
Score: 5.5
Sequence: TCGTGAAAGCGTTCACAT
Locus tag: SAV_3016
Name: whiE
Funciton: WhiB-family transcriptional regulator involved in differentiation and sporulation
whiE
WhiB-family transcriptional regulator involved in differentiation and sporulation

Position: -94
Score: 6
Sequence: TTGTGCACGCGTTCACAA
Locus tag: SAV_4738
Name: rex
Funciton: Redox-sensitive transcriptional regulator Rex
Locus tag: SAV_4739
Name: hemA
Funciton: Glutamyl-tRNA reductase (EC 1.2.1.70)
Locus tag: SAV_4740
Name: hemC
Funciton: Porphobilinogen deaminase (EC 2.5.1.61)
Locus tag: SAV_4741
Name: hemD
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
rex
Redox-sensitive transcriptional regulator Rex
hemA
Glutamyl-tRNA reductase (EC 1.2.1.70)
hemC
Porphobilinogen deaminase (EC 2.5.1.61)
hemD
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)

Position: -212
Score: 5
Sequence: TCGTGAATTGATTCACGA
Locus tag: SAV_4616
Name: hppA
Funciton: Pyrophosphate-energized proton pump (EC 3.6.1.1)
hppA
Pyrophosphate-energized proton pump (EC 3.6.1.1)

Position: -136
Score: 5.2
Sequence: TTGTGAAGGGGCGCACGA
Locus tag: SAV_3529
Name: ndh
Funciton: NADH dehydrogenase (EC 1.6.99.3)
ndh
NADH dehydrogenase (EC 1.6.99.3)

Position: -154
Score: 5.1
Sequence: TTGTGATACGGTTCACGA
Locus tag: SAV_2888
Name: atpI
Funciton: ATP synthase protein I
Locus tag: SAV_2887
Name: atpB
Funciton: ATP synthase A chain (EC 3.6.3.14)
Locus tag: SAV_2886
Name: atpE
Funciton: ATP synthase C chain (EC 3.6.3.14)
Locus tag: SAV_2885
Name: atpF
Funciton: ATP synthase B chain (EC 3.6.3.14)
Locus tag: SAV_2884
Name: atpH
Funciton: ATP synthase delta chain (EC 3.6.3.14)
Locus tag: SAV_2883
Name: atpA
Funciton: ATP synthase alpha chain (EC 3.6.3.14)
Locus tag: SAV_2882
Name: atpG
Funciton: ATP synthase gamma chain (EC 3.6.3.14)
Locus tag: SAV_2881
Name: atpD
Funciton: ATP synthase beta chain (EC 3.6.3.14)
Locus tag: SAV_2880
Name: atpC
Funciton: ATP synthase epsilon chain (EC 3.6.3.14)
atpI
ATP synthase protein I
atpB
ATP synthase A chain (EC 3.6.3.14)
atpE
ATP synthase C chain (EC 3.6.3.14)
atpF
ATP synthase B chain (EC 3.6.3.14)
atpH
ATP synthase delta chain (EC 3.6.3.14)
atpA
ATP synthase alpha chain (EC 3.6.3.14)
atpG
ATP synthase gamma chain (EC 3.6.3.14)
atpD
ATP synthase beta chain (EC 3.6.3.14)
atpC
ATP synthase epsilon chain (EC 3.6.3.14)

Position: -164
Score: 5.4
Sequence: TTGTGACCTGCTTCACAT
Locus tag: SAV_4837
Name: nuoA
Funciton: NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3)
Locus tag: SAV_4838
Name: nuoB
Funciton: NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3)
Locus tag: SAV_4839
Name: nuoC
Funciton: NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)
Locus tag: SAV_4840
Name: nuoD
Funciton: NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)
Locus tag: SAV_4841
Name: nuoE
Funciton: NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)
Locus tag: SAV_4842
Name: nuoF
Funciton: NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)
Locus tag: SAV_4843
Name: nuoG
Funciton: NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)
Locus tag: SAV_4844
Name: nuoH
Funciton: NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)
Locus tag: SAV_4845
Name: nuoI
Funciton: NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3)
Locus tag: SAV_4846
Name: nuoJ
Funciton: NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)
Locus tag: SAV_4847
Name: nuoK
Funciton: NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)
Locus tag: SAV_4848
Name: nuoL
Funciton: NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)
Locus tag: SAV_4849
Name: nuoM
Funciton: NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3)
Locus tag: SAV_4850
Name: nuoN
Funciton: NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)
nuoA
NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3)
nuoB
NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3)
nuoC
NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)
nuoD
NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)
nuoE
NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)
nuoF
NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)
nuoG
NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)
nuoH
NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)
nuoI
NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3)
nuoJ
NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)
nuoK
NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)
nuoL
NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)
nuoM
NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3)
nuoN
NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)

Position: -16
Score: 3.9
Sequence: ATGCGAAACTTTTCACAT
Locus tag: SAV_4798
Name: resA
Funciton: Thiol:disulfide oxidoreductase related to ResA
Locus tag: SAV_4799
Name: ccdA
Funciton: Cytochrome c-type biogenesis protein CcdA (DsbD analog)
Locus tag: SAV_4800
Name: resB
Funciton: Ccs1/ResB-related putative cytochrome C-type biogenesis protein
Locus tag: SAV_4801
Name: resC
Funciton: Cytochrome c-type biogenesis protein CcsA/ResC
resA
Thiol:disulfide oxidoreductase related to ResA
ccdA
Cytochrome c-type biogenesis protein CcdA (DsbD analog)
resB
Ccs1/ResB-related putative cytochrome C-type biogenesis protein
resC
Cytochrome c-type biogenesis protein CcsA/ResC

Position: -36
Score: 4.8
Sequence: TTGTGCACCGTCGCACAA
Locus tag: SAV_3538
Name: SCO3101
Funciton: Putative lipoprotein
Locus tag: SAV_3537
Name: mazG
Funciton: Triphosphate pyrophosphohydrolase MazG
SCO3101
Putative lipoprotein
mazG
Triphosphate pyrophosphohydrolase MazG

Position: -98
Score: 6
Sequence: ATGTGAACGCGTTCACAA
Locus tag: SAV_4260
Name: cydA
Funciton: Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-)
Locus tag: SAV_4259
Name: cydB
Funciton: Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-)
Locus tag: SAV_4258
Name: cydCD
Funciton: ABC transporter permease CydC / ATP-binding protein CydD
cydA
Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-)
cydB
Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-)
cydCD
ABC transporter permease CydC / ATP-binding protein CydD
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