Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of LexA in Actinosynnema mirum DSM 43827

Properties
Regulator type: Transcription factor
TF locus tag: Amir_3974, Amir_1434
Regulator family: LexA
Regulation mode: repressor
Biological process: SOS response
Effector: DNA damage
Regulog: LexA - Frankineae/Propionibacterineae/Pseudonocardiaceae
Statistics of regulated genes:
- Genes 12
- Operons 8
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 68 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -157
Score: 3.8
Sequence: ACGACCTCGTGCTCGA
Locus tag: Amir_3974
Name: lexA
Funciton: SOS-response repressor and protease LexA (EC 3.4.21.88)
lexA
SOS-response repressor and protease LexA (EC 3.4.21.88)

Position: -87
Score: 4.2
Sequence: TCGACCACCCGGTCGT
Position: -26
Score: 5.8
Sequence: TCGAACAGACGTTCGA
Locus tag: Amir_5585
Name: dprA
Funciton: DNA protecting protein DprA
dprA
DNA protecting protein DprA

Position: -58
Score: 5
Sequence: TCGAACTGGTGTTCGC
Locus tag: Amir_1692
Name: ruvC
Funciton: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)
Locus tag: Amir_1691
Name: ruvA
Funciton: Holliday junction DNA helicase RuvA
Locus tag: Amir_1690
Name: ruvB
Funciton: Holliday junction DNA helicase RuvB
ruvC
Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)
ruvA
Holliday junction DNA helicase RuvA
ruvB
Holliday junction DNA helicase RuvB

Position: -184
Score: 5.6
Sequence: TCGAACAACCGTTCGA
Position: -168
Score: 5.3
Sequence: TCGAACGCCCGTGCGA
Position: -103
Score: 5.6
Sequence: TCGAACAGGTGTTTGA
Locus tag: Amir_1434
Name: lexA
Funciton: SOS-response repressor and protease LexA (EC 3.4.21.88)
lexA
SOS-response repressor and protease LexA (EC 3.4.21.88)

Position: -100
Score: 5.5
Sequence: TCGAACGCGTGTTTGA
Locus tag: Amir_2280
Name: gyrB
Funciton: Topoisomerase IV, subunit B (EC 5.99.1.-)
Locus tag: Amir_2281
Name: gyrA
Funciton: Topoisomerase IV, subunit A (EC 5.99.1.-)
gyrB
Topoisomerase IV, subunit B (EC 5.99.1.-)
gyrA
Topoisomerase IV, subunit A (EC 5.99.1.-)

Position: -38
Score: 5.6
Sequence: TCGAACATGTGTTCGG
Locus tag: Amir_5483
Name: uvrA
Funciton: Excinuclease ABC, subunit A
uvrA
Excinuclease ABC, subunit A

Position: -264
Score: 4.2
Sequence: CCGACCAGGCGTTGGA
Position: -151
Score: 5.7
Sequence: TCGAACACCTGTTCGG
Locus tag: Amir_1419
Name: recA
Funciton: Recombinase A
Locus tag: Amir_1420
Name: recX
Funciton: Regulatory protein RecX
recA
Recombinase A
recX
Regulatory protein RecX

Position: 16
Score: 4.1
Sequence: ACGAATCCGCGTTCGG
Locus tag: Amir_0958
Name: hsdR
Funciton: Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)
hsdR
Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD