Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of IolR in Streptomyces coelicolor A3(2)

Properties
Regulator type: Transcription factor
TF locus tag: SCO6974, SCO6256
Regulator family: GntR/Others
Regulation mode:
Biological process: Inositol utilization
Effector:
Regulog: IolR - Streptomycetaceae
Statistics of regulated genes:
- Genes 24
- Operons 10
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 35 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -153
Score: 4.9
Sequence: GCAATGTCCGGACAATGT
Locus tag: SCO6257
Name: iolTA2
Funciton: Inositol ABC transport system, sugar-binding protein
Locus tag: SCO6258
Name: iolTB2
Funciton: Inositol ABC transport system, permease protein
Locus tag: SCO6259
Name: iolTC2
Funciton: Inositol ABC transport system, ATP-binding protein
iolTA2
Inositol ABC transport system, sugar-binding protein
iolTB2
Inositol ABC transport system, permease protein
iolTC2
Inositol ABC transport system, ATP-binding protein

Position: -103
Score: 4.6
Sequence: TCTTTGTCCTGTCAAAAG
Locus tag: SCO6988
Name: iolG3
Funciton: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)
iolG3
Myo-inositol 2-dehydrogenase (EC 1.1.1.18)

Position: -57
Score: 4.9
Sequence: CGTTTGTCAGGACAAGAA
Locus tag: SCO6985
Name: SCO6985
Funciton: Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin
Locus tag: SCO6984
Name: iolG2
Funciton: Myo-inositol 2-dehydrogenase 1 (EC 1.1.1.18)
SCO6985
Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin
iolG2
Myo-inositol 2-dehydrogenase 1 (EC 1.1.1.18)

Position: -86
Score: 5.1
Sequence: CGAATGTCCGGACAAAAC
Locus tag: SCO2727
Name: iolD
Funciton: Epi-inositol hydrolase (EC 3.7.1.-)
Locus tag: SCO2726
Name: iolA
Funciton: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
iolD
Epi-inositol hydrolase (EC 3.7.1.-)
iolA
Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)

Position: -123
Score: 4.8
Sequence: ACTTTGTCAAGACATCAT
Position: -91
Score: 4.6
Sequence: CGAATGTAAGTACAAAGT
Locus tag: SCO6978
Name: iolC
Funciton: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)
Locus tag: SCO6977
Name: iolJ
Funciton: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)
Locus tag: SCO6976
Name: iolB
Funciton: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)
Locus tag: SCO6975
Name: iolD
Funciton: Epi-inositol hydrolase (EC 3.7.1.-)
Locus tag: SCO6974
Name: iolR
Funciton: Inositol utilization transcriptional regulator, GntR family
iolC
5-keto-2-deoxygluconokinase (EC 2.7.1.92)
iolJ
5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)
iolB
5-deoxy-glucuronate isomerase (EC 5.3.1.-)
iolD
Epi-inositol hydrolase (EC 3.7.1.-)
iolR
Inositol utilization transcriptional regulator, GntR family

Position: -153
Score: 4.9
Sequence: GCAATGTCCGGACAATGT
Locus tag: SCO6257
Name: iolTA
Funciton: Inositol ABC transport system sugar-binding protein
Locus tag: SCO6258
Name: iolTB
Funciton: Inositol ABC transport system permease protein
Locus tag: SCO6259
Name: iolTC
Funciton: Inositol ABC transport system ATP-binding protein
Locus tag: SCO6260
Name: SCO6259
Funciton: Putative sugar kinase
iolTA
Inositol ABC transport system sugar-binding protein
iolTB
Inositol ABC transport system permease protein
iolTC
Inositol ABC transport system ATP-binding protein
SCO6259
Putative sugar kinase

Position: -55
Score: 5.4
Sequence: CGATTGTCCGGACATACG
Locus tag: SCO6255
Name: iolG
Funciton: Inositol 2-dehydrogenase (EC 1.1.1.18 )
iolG
Inositol 2-dehydrogenase (EC 1.1.1.18 )

Position: -180
Score: 4.6
Sequence: ACTTTGTACTTACATTCG
Position: -148
Score: 4.8
Sequence: ATGATGTCTTGACAAAGT
Locus tag: SCO6979
Name: iolTA2
Funciton: Inositol ABC transport system sugar-binding protein
Locus tag: SCO6980
Name: iolTB2
Funciton: Inositol ABC transport system permease protein
Locus tag: SCO6981
Name: iolTC2
Funciton: Inositol ABC transport system ATP-binding protein
Locus tag: SCO6982
Name: iolE2
Funciton: Inosose dehydratase (EC 4.2.1.44)
iolTA2
Inositol ABC transport system sugar-binding protein
iolTB2
Inositol ABC transport system permease protein
iolTC2
Inositol ABC transport system ATP-binding protein
iolE2
Inosose dehydratase (EC 4.2.1.44)

Position: -90
Score: 4.9
Sequence: TTCTTGTCCTGACAAACG
Locus tag: SCO6986
Name: iolR2
Funciton: Transcriptional regulator for inositol utilization, LacI family
iolR2
Transcriptional regulator for inositol utilization, LacI family

Position: -91
Score: 5.4
Sequence: CGTATGTCCGGACAATCG
Locus tag: SCO6256
Name: iolR
Funciton: Inositol utilization transcriptional regulator, GntR family
iolR
Inositol utilization transcriptional regulator, GntR family
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